Group 1 - The pharmaceutical sector is experiencing significant activity, with notable stocks such as Sanofi and Yipinhong reaching their daily limit up of 19.99%, and others like Shutaishen rising over 9% [1] - Major pharmaceutical companies reported impressive Q1 earnings, with BeiGene achieving a revenue of 8.048 billion yuan, a 50.2% increase from the previous year, and a significant reduction in net losses [1] - Innovent Biologics reported a revenue of 381 million yuan for Q1, marking a 129.92% year-on-year growth, and a net profit of 18 million yuan, up 112.62% year-on-year, indicating a turnaround to profitability [1] Group 2 - Wanlian Securities forecasts a performance divergence in the pharmaceutical sub-sectors for Q1 2024 and 2025, with strong revenue and profit growth expected in medical R&D outsourcing, hospitals, and other biological products [2] - The chemical pharmaceutical sector is gaining market attention, focusing on innovation-driven growth, domestic production, and policy immunity [2] - China Galaxy notes that the pharmaceutical sector has undergone a long adjustment period, resulting in low valuations and underweight public holdings, with expectations for policy support and market demand recovery to drive growth [2]

证券代码：002821 证券简称：凯莱英 公告编号：2025-033 国公司法》、《深圳证券交易所股票上市规则》等有关法律、行政法规、部门规 章、规范性文件和《公司章程》的相关规定。 现场会议召开时间：2025年6月11日下午14:00 网络投票时间：2025年6月11日，其中，通过深圳证券交易所交易系统进行 网络投票的时间为2025年6月11日上午9：15-9：25，9：30-11：30，下午13:00- 凯莱英医药集团（天津）股份有限公司 关于召开2024年度股东大会、2025年第二次A股类别股东 大会及2025年第二次H股类别股东大会通知的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整， 没有虚假记载、误导性陈述或重大遗漏。 凯莱英医药集团（天津）股份有限公司（以下简称"公司"）将于2025年6月 类别股东大会及2025年第二次H股类别股东大会。现将本次会议有关事项公告如 下： 一、召开会议的基本情况 年第二次H股类别股东大会 （1）现场投票：股东本人出席现场会议或者通过授权委托书（见附件）委 托他人出席现场会议；公司H股股东可以通过现场或委托投票方式参加本次股东 大会，有关具体方式参见 ...

Group 1 - The core point of the news is the performance and holdings of the China Europe Medical Health Mixed A Fund, which has seen a recent decline in net value and varying returns over different time frames [1] - As of May 7, 2025, the latest net value of the fund is 1.5753 yuan, reflecting a decrease of 1.28%. The fund's return over the past month is -2.61%, ranking 4118 out of 4649 in its category. Over the past three months, the return is 4.24%, ranking 1179 out of 4597, and since the beginning of the year, the return is 1.73%, ranking 2415 out of 4556 [1] - The top ten stock holdings of the fund account for a total of 55.30%, with significant positions in companies such as Heng Rui Pharmaceutical (10.60%), WuXi AppTec (9.95%), and Kanglong Chemical (6.24%) [1] Group 2 - The China Europe Medical Health Mixed A Fund was established on September 29, 2016, and as of March 31, 2025, it has a total scale of 15.613 billion yuan. The fund manager is Ms. Ge Lan [1] - Ms. Ge Lan has a background in biomedical engineering with a Ph.D. from Northwestern University in the United States. She has held various research and fund management positions before becoming the manager of the China Europe Medical Health Mixed Fund [2]

Core Insights - The global and US innovative drug VC&PE financing amounts are expected to grow by 1.93% and 5.29% respectively in 2024, indicating a recovery in the innovative drug financing environment [1] - The demand for research and development in fields such as peptides and ADCs is strong, leading to an increase in outsourcing needs in these areas [1][2] Macro Perspective - The global innovative drug financing environment is recovering, with significant growth in the demand for innovative research in specific fields like peptides and ADCs, which is expected to enhance the CXO industry's outlook [1] - According to Crunchbase, the VC&PE financing for innovative drugs in 2024 shows positive growth, marking an improvement in the financing environment [1] Micro Perspective - CXO listed companies are seeing a recovery in new orders, with many companies like WuXi AppTec, WuXi Biologics, and others reporting a year-on-year increase of over 20% in new orders [3] - The production capacity of domestic CXO companies is mature, ensuring timely delivery of orders, which is expected to lead to double-digit revenue growth for several companies in 2025 [3] Target Companies - Recommended companies to watch include WuXi AppTec (603259.SH, 02359), WuXi Biologics (02269), WuXi AppTec (02268), Kelun Pharmaceutical (002821.SZ, 06821), and others [4]

Core Insights - Gao Yi Asset Management recently conducted research on a listed company, Kailai Ying, revealing positive financial performance in Q1 2025 [1] Financial Performance Summary - Kailai Ying reported a main revenue of 1.541 billion yuan, an increase of 10.1% year-on-year [1] - The net profit attributable to shareholders was 327 million yuan, reflecting a year-on-year growth of 15.83% [1] - The net profit after deducting non-recurring items was 305 million yuan, up by 20.14% year-on-year [1] - The company's debt ratio stood at 11.58% [1] - Investment income amounted to 10.2752 million yuan, while financial expenses were -44.9396 million yuan [1] - The gross profit margin was reported at 42.54% [1] Company Overview - Gao Yi Asset Management is a prominent private equity fund management company in China, known for its strong research capabilities and large management scale [2] - The firm focuses on capital markets and aims to provide top-notch research support and resources to its investment managers [2] - The investment team consists of over 30 members, including experienced managers and award-winning fund managers from leading fund companies [2] - The company is registered in Shanghai and has teams located in Shenzhen, Shanghai, and Beijing [2]

Investment Rating - The investment rating for the company is "Buy" (maintained) [4] Core Views - The company achieved a revenue of 1.541 billion yuan in Q1 2025, representing a year-over-year growth of 10.10%, and a net profit attributable to shareholders of 327 million yuan, with a year-over-year increase of 15.83%. The non-recurring net profit was 305 million yuan, reflecting a year-over-year growth of 20.14% [1] - The emerging business segment saw revenue growth exceeding 80% year-over-year, driven by increased market expansion efforts and enhanced competitiveness, particularly in peptide, oligonucleotide, and ADC businesses. The outlook for the emerging business remains positive [1][2] - The gross margin for Q1 2025 was 42.54%, with the emerging business gross margin significantly improving to 33.05%, a year-over-year increase of 15.75%. This improvement is attributed to higher capacity utilization from sustained order deliveries [2] - The company forecasts EPS for 2025-2027 to be 2.90, 3.45, and 4.19 yuan, respectively, with a PE ratio of 23 times based on the closing price on April 23, 2025. The company is expected to maintain strong growth potential, particularly in the emerging business segment [2] Financial Summary - For 2025E, the company expects revenue of 6.629 billion yuan, a year-over-year increase of 14.21%, and a net profit of 1.045 billion yuan, reflecting a growth of 10.16% [7] - The gross margin is projected to be 42.43% in 2025E, with a net margin of 15.72% [8] - The company’s total assets are expected to reach 21.751 billion yuan by 2025E, with total liabilities of 2.771 billion yuan [8]

Group 1 - The innovative pharmaceutical ETF (560900) has risen by 1.80%, with the underlying index, the China Innovative Drug Industry Index (931152), increasing by 1.60% [1] - Key stocks such as Kailaiying (002821) rose by 10.01%, Maiwei Biotech (688062) by 7.23%, and Rongchang Biotech (688331) by 6.57% [1] - Galaxy Securities indicates that innovative pharmaceutical companies are in a critical transformation period, with Changchun High-tech's R&D investment reaching 2.69 billion yuan in 2024, a year-on-year increase of 11.20%, accounting for nearly 20% of revenue [1] Group 2 - Morgan Asset Management is integrating its "Global Vision Investment Technology" product line to assist investors in capturing investment opportunities in quality tech companies globally [2] - The actively managed Morgan Emerging Power Fund aims to grasp emerging industry trends from a long-term perspective, while the Morgan Smart Connectivity Fund focuses on opportunities in the AI sector [2] - The Morgan Pacific Technology Fund selects quality tech companies in the Pacific region [2] Group 3 - The passive investment options include the Morgan Hang Seng Technology ETF (513890) for exposure to Hong Kong tech assets and the Morgan China Innovative Drug Industry ETF (560900) for Chinese innovative pharmaceutical companies [3] - The Morgan NASDAQ 100 Index Fund provides one-click access to global tech leaders [3]

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Financial Performance - The company's revenue for Q1 2025 reached CNY 1.54 billion, representing a year-on-year increase of 10.10%[7] - Net profit attributable to shareholders was CNY 326.61 million, up 15.83% compared to the same period last year[7] - The net profit margin increased by 5.73 percentage points, indicating a stronger growth in net profit relative to revenue[8] - The company experienced a significant increase in revenue from emerging businesses, which grew over 80% year-on-year[8] - Total operating revenue for the current period reached ¥1,541,215,508.36, an increase of 10.1% compared to ¥1,399,808,311.93 in the previous period[21] - Net profit for the current period was ¥324,571,255.22, representing a growth of 16.1% from ¥279,529,194.27 in the previous period[22] - Earnings per share (EPS) increased to ¥0.89 from ¥0.76, reflecting a 17.1% rise[23] Margins and Costs - The gross margin for the small molecule business was 45.17%, while the emerging business, including peptides and oligonucleotides, saw a gross margin of 33.05%[8] - Total operating costs amounted to ¥1,218,635,250.34, up 6.9% from ¥1,139,986,870.77 in the prior period[21] - Research and development expenses were ¥137,876,668.92, down 18.6% from ¥169,442,435.66 in the previous period[22] Cash Flow and Investments - The company reported a decrease in net cash flow from operating activities by 8.42%, totaling CNY 449.34 million[7] - Cash inflow from operating activities totaled ¥1,919,221,084.13, compared to ¥1,873,810,971.80 in the previous period, indicating a growth of 2.4%[24] - The net cash flow from operating activities was 449,341,852.23, a decrease of 8.4% compared to 490,666,474.36 from the previous period[25] - The net cash flow from investing activities was 843,986,349.07, a significant improvement from a negative cash flow of -284,603,126.59 in the previous period[25] - The cash inflow from investment activities was 3,083,222,004.40, down from 3,373,389,580.58 in the previous period[25] - The cash received from investment income was 50,475,852.08, an increase from 33,380,385.72 in the previous period[25] - The cash received from other investment activities was 14,158,000.00, significantly higher than 1,509,194.86 in the previous period[25] Assets and Liabilities - Total assets at the end of the reporting period were CNY 19.45 billion, a slight increase of 0.82% from the previous year[7] - The total assets of the company as of March 31, 2025, amounted to RMB 19,447,176,497.82, an increase from RMB 19,288,557,691.02 at the beginning of the period[18] - The company's cash and cash equivalents increased to RMB 6,801,983,716.00 from RMB 5,789,408,498.03, reflecting a growth of approximately 17.4%[18] - Accounts receivable decreased to RMB 1,663,505,038.74 from RMB 1,811,008,371.43, indicating a decline of about 8.1%[18] - The total current assets rose to RMB 11,151,587,441.54 from RMB 11,050,175,723.88, showing an increase of approximately 0.9%[18] - Non-current assets totaled RMB 8,295,589,056.28, up from RMB 8,238,381,967.14, representing a growth of about 0.7%[18] - The total liabilities decreased to ¥2,252,047,978.35 from ¥2,425,984,466.06, a reduction of 7.1%[20] - Total equity attributable to shareholders increased to ¥17,179,977,026.38 from ¥16,845,385,169.37, marking a growth of 2.0%[20] Changes in Liabilities - The total liabilities increased, with accounts payable rising to RMB 467,674,845.13 from RMB 450,845,943.46, an increase of about 3.7%[19] - The company's contract liabilities increased to RMB 352,634,510.47 from RMB 269,940,917.65, reflecting a significant rise of approximately 30.6%[19] - The company reported a decrease in other payables from RMB 514,561,172.27 to RMB 444,522,700.85, a decline of about 13.6%[19] Shareholder Information - The company's weighted average return on equity improved to 1.92%, up from 1.60% year-on-year[7] - The company has a total of 5,716,000 shares held in its repurchase special securities account as of March 31, 2025[15]

Financial Performance - For the first quarter of 2025, the company reported a revenue of RMB 1,541,215,508.36, representing a year-on-year increase of 10.10%[9] - The net profit attributable to shareholders was RMB 326,607,817.72, reflecting a growth of 15.83% compared to the same period last year[9] - The net profit after deducting non-recurring gains and losses was RMB 305,112,828.34, which is a 20.14% increase year-on-year[9] - Basic and diluted earnings per share increased to RMB 0.89, up 17.11% from RMB 0.76 in the previous year[9] - Operating profit amounted to RMB 358,637,868.11, reflecting a growth of 21.7% from RMB 294,688,697.62 in the prior period[26] - Net profit for the period was RMB 324,571,255.22, up 16.1% from RMB 279,529,194.27 year-over-year[27] - The total comprehensive income for the current period was RMB 325,416,000, up from RMB 279,822,000 in the previous period[35] - Adjusted net profit attributable to shareholders for Q1 2025 was RMB 330,393,000, compared to RMB 267,120,000 in Q1 2024, indicating a growth of approximately 23.7%[42] - The adjusted net profit margin for Q1 2025 improved to 21.44%, up from 19.08% in Q1 2024[42] Assets and Liabilities - Total assets at the end of the reporting period were RMB 19,447,176,497.82, a 0.82% increase from the previous year-end[9] - The equity attributable to shareholders rose to RMB 17,179,977,026.38, marking a 1.99% increase compared to the previous year-end[9] - Total liabilities decreased to RMB 2,252,047,978.35 from RMB 2,425,984,466.06, representing a reduction of 7.1%[24] - Current assets totaled RMB 11,151,587,441.54, slightly up from RMB 11,050,175,723.88 at the start of the period, indicating a 0.9% increase[22] - The company's total assets less current liabilities amounted to RMB 17,888,660,000, an increase from RMB 17,579,211,000 in the previous year[38] Cash Flow - The company's cash flow from operating activities showed a net decrease of 8.42%, amounting to RMB 449,341,852.23[9] - Operating cash flow for the current period was RMB 449,341,852.23, a decrease of 8.4% from RMB 490,666,474.36 in the previous period[30] - The net increase in cash and cash equivalents for the current period was RMB 1,307,854,379.23, significantly higher than RMB 3,058,460.18 in the previous period[31] - The company reported a net cash inflow from investing activities of RMB 843,986,000 in Q1 2025, contrasting with a net cash outflow of RMB 284,603,000 in Q1 2024[41] - Cash and bank balances at the end of the period were RMB 6,801,984,000, an increase from RMB 5,789,408,000 in the previous year[37] Investments and Expenses - Trading financial assets decreased by 50.35% to ¥764,449,856.30 due to a reduction in low-risk bank deposits[14] - Financial expenses decreased by 42.61% to ¥(44,939,637.49) primarily due to a decrease in exchange gains from currency fluctuations[14] - Investment income cash receipts increased by 51.21% to ¥50,475,852.08 due to higher fixed-term interest income[14] - Cash paid for investments decreased by 40.02% to ¥1,992,870,856.24 mainly due to a reduction in purchases of low-risk bank wealth management products[14] - The company's depreciation expense for property, plant, and equipment was RMB 114,895,000 in Q1 2025, compared to RMB 103,908,000 in Q1 2024, reflecting an increase of approximately 10.5%[40] Shareholder Information - The total number of common shareholders at the end of the reporting period was 43,585[15] - ASYMCHEM LABORATORIES, INCORPORATED holds 31.93% of shares, totaling 115,133,168 shares[16] - The top ten shareholders include various entities, with the largest being ASYMCHEM LABORATORIES, INCORPORATED[16] - The company has not reported any significant changes in the participation of major shareholders in margin financing activities[20] Business Development - The company continues to implement cost reduction and efficiency enhancement measures to support ongoing business growth[10] - The company plans to continue expanding its market presence and investing in new product development to drive future growth[26] - The company’s small molecule CDMO business maintained stable development with a gross margin of 45.17%[10] - Emerging businesses, particularly in peptides, oligonucleotides, and ADCs, achieved over 80% revenue growth year-on-year with a gross margin of 33.05%[10]