周四（8月21日），A股市场全天震荡调整，三大指数涨跌不一。午后市场抛压逐渐加重，沪指在大金融顶盘靠近3800点失败后回落，场内炸板率激增。两 市全天成交额2.42万亿元，连续7个交易日突破2万亿元。盘面上，市场热点持续轮动，个股跌多涨少，全市场超3000只个股下跌。 展望后市，浙商证券认为，考虑到本轮牛市的性质是"系统性'慢'牛"，"雨露均沾"是行情"底色"，因此"大金融+泛科技"的搭配有望持续战胜基准。建议适度 忽略短线走势，在重要支撑附近分别增加短线、中线配置。行业配置方面，继续采取"大金融+泛科技"均衡配置（银行、非银等金融+国防军工/计算机//电子 等科技成长）。 【ETF全知道热点收评】重点聊聊化工、制药和金融科技等三个行业主题的交易和基本面情况。 一、化工板块狂飙，化工ETF（516020）摸高1.89%！机构：化工板块供需格局预期改善，估值底部弹性空间充足 化工板块今日继续猛攻！反映化工板块整体走势的化工ETF（516020）开盘后持续上攻，盘中场内价格涨幅一度达到1.89%，尾盘有所回落，但截至收盘， 仍有1.16%的涨幅。 成份股方面，钛白粉、复合肥、氮肥等板块部分个股涨幅居前。截至收盘， ...

Market Performance - The pharmaceutical sector experienced a slight decline of -0.07% on August 20, 2025, underperforming the CSI 300 index by 1.21 percentage points, ranking 31st among 31 sub-industries in the Shenwan classification [1] - Among sub-industries, hospitals (+0.63%), blood products (+0.30%), and medical research outsourcing (+0.29%) showed positive performance, while other biopharmaceuticals (-1.02%), in vitro diagnostics (-0.46%), and medical consumables (-0.38%) lagged behind [1] - Top three gainers in individual stocks were Huabang Health (+10.11%), Jimin Health (+10.02%), and Tianmu Pharmaceutical (+10.01%), while the biggest losers were Xintian Pharmaceutical (-10.01%), Fuyuan Pharmaceutical (-10.00%), and Chengyi Pharmaceutical (-9.99%) [1] Industry News - Madrigal announced that the European Commission has conditionally approved its drug Rezdiffra (resmetirom) for treating adult patients with moderate to severe liver fibrosis due to non-alcoholic steatohepatitis (MASH) [2] - Resmetirom is a "first-in-class" oral thyroid hormone receptor (THR)-β selective agonist targeting the underlying causes of MASH [2] - This approval marks the first MASH therapy to receive EU approval, based on results from the pivotal MAESTRO-NASH Phase 3 clinical trial, which showed that 25.9% and 29.9% of patients in the 80mg and 100mg Resmetirom groups, respectively, achieved symptom resolution without worsening liver fibrosis at week 52, compared to 9.7% in the placebo group (P<0.001) [2] Company News - Heng Rui Medicine (600276) reported a revenue of 15.761 billion yuan for the first half of 2025, a year-on-year increase of 15.88%, with a net profit attributable to shareholders of 4.450 billion yuan, up 29.67% [3] - Lizhu Group (000513) posted a revenue of 6.272 billion yuan for the first half of 2025, a slight decline of 0.17%, while net profit attributable to shareholders increased by 9.40% to 1.281 billion yuan [3] - Te Bao Biological (688278) achieved a revenue of 1.511 billion yuan, reflecting a growth of 26.96%, with a net profit of 428 million yuan, up 40.60% [3] - Zhong Yao Holdings (000950) reported a revenue of 41.188 billion yuan, a growth of 3.54%, and a net profit of 282 million yuan, increasing by 18.56% [3]

Core Viewpoint - The Agricultural Bank of China Healthcare Fund (000913) has shown positive performance with a recent net value of 1.9672 yuan, reflecting a growth of 0.83% [1]. Performance Summary - The fund's one-month return is 2.34%, ranking 946 out of 1025 in its category [1]. - Over the past six months, the fund has achieved a return of 43.83%, ranking 46 out of 986 [1]. - Year-to-date, the fund's return stands at 43.08%, with a ranking of 88 out of 976 [1]. Holdings Overview - The top ten holdings of the Agricultural Bank of China Healthcare Fund account for a total of 51.10% of the portfolio, with the following key positions: - Heng Rui Medicine: 8.16% - Zai Lab: 7.99% - Xin Li Tai: 5.84% - Hotgen Biotech: 5.63% - Kelun Pharmaceutical: 5.02% - HAOYOBIO: 4.36% - BeiGene: 3.61% - Eucure Biopharma: 3.58% - Ausun Pharmaceutical: 3.52% - Bide Pharmaceutical: 3.39% [1]. Fund Details - The Agricultural Bank of China Healthcare Fund was established on February 10, 2015, and as of June 30, 2025, it has a total asset size of 1.441 billion yuan [1]. - The fund manager is Meng Yuan, who has a master's degree and has held various positions in the financial sector, including roles at Bank of China Fund Management and Agricultural Bank of China Asset Management [1].

Group 1 - The A-share pharmaceutical sector showed strong performance, with the only ETF tracking the pharmaceutical index (562050) reaching a record closing price of 1.108 yuan, up 1.45% [1] - Major pharmaceutical companies like Heng Rui Medicine and Bai Jie Shen Zhou reported significant gains, with Heng Rui Medicine up 1.81% and Bai Jie Shen Zhou up 2.42% [1] - The overall market sentiment was positive, with 18 out of 50 companies in the ETF having disclosed their mid-year results, and 12 of those showing positive net profit growth [3] Group 2 - Heng Rui Medicine's mid-year report indicated a revenue of 15.76 billion yuan, a year-on-year increase of 15.9%, and a net profit of 4.45 billion yuan, up 29.7% [3] - Bai Jie Shen Zhou exceeded expectations with a projected revenue growth of 46% and a net profit increase of 115.63% [3] - Notable performers included Da Ren Tang with a net profit growth of 193% and Gan Li Pharmaceutical with a doubling of net profit [4] Group 3 - High-level discussions emphasized the need for increased support for the biopharmaceutical industry, focusing on high-quality technological supply and policy support [5] - The strategy includes promoting the modernization and industrialization of traditional Chinese medicine through innovation [5] - Investors are encouraged to consider the pharmaceutical ETF (562050) and its associated funds, which focus on leading pharmaceutical companies and innovative drugs [5]

周四（8月21日），A股市场全天震荡调整，三大指数涨跌不一。午后市场抛压逐渐加重，沪指在大金 融顶盘靠近3800点失败后回落，场内炸板率激增。两市全天成交额2.42万亿元，连续7个交易日突破2万 亿元。盘面上，市场热点持续轮动，个股跌多涨少，全市场超3000只个股下跌。 展望后市，浙商证券认为，考虑到本轮牛市的性质是"系统性'慢'牛"，"雨露均沾"是行情"底色"，因 此"大金融+泛科技"的搭配有望持续战胜基准。建议适度忽略短线走势，在重要支撑附近分别增加短 线、中线配置。行业配置方面，继续采取"大金融+泛科技"均衡配置（银行、非银等金融+国防军工/计 算机//电子等科技成长）。 【ETF全知道热点收评】重点聊聊化工、制药和金融科技等三个行业主题的交易和基本面情况。 一、化工板块狂飙，化工ETF（516020）摸高1.89%！机构：化工板块供需格局预期改善，估值底部弹 性空间充足 化工板块今日继续猛攻！反映化工板块整体走势的化工ETF（516020）开盘后持续上攻，盘中场内价格 涨幅一度达到1.89%，尾盘有所回落，但截至收盘，仍有1.16%的涨幅。 成份股方面，钛白粉、复合肥、氮肥等板块部分个股涨幅居前。截至 ...

Core Insights - The company reported a significant increase in revenue and profit for the first half of 2025, with total revenue reaching 15.76 billion yuan, a year-on-year growth of 15.88%, and net profit attributable to shareholders at 4.45 billion yuan, up 29.67% [1] - The growth is primarily driven by the continuous expansion of the innovative drug business, which accounted for over 60% of total revenue [1][2] - The company has made substantial progress in its internationalization strategy, forming high-value licensing agreements with multinational companies such as Merck and GSK, indicating increasing recognition of its R&D capabilities [1][4] Financial Performance - The company achieved a record high in operating cash flow, amounting to 4.3 billion yuan, reflecting a year-on-year increase of 41.80% [1] - R&D investment for the period was 3.87 billion yuan, with cumulative R&D spending nearing 50 billion yuan [2] - The innovative drug segment generated sales of 7.57 billion yuan and licensing income of nearly 2 billion yuan, making it the core engine of revenue growth [2] R&D and Innovation - The company has established multiple platforms for drug discovery, including the Heng Rui-Ling Shu platform and AI-assisted drug development platform, enhancing drug discovery efficiency [3] - A total of 15 new molecules entered clinical stages during the reporting period, with over 100 innovative products in clinical development globally [3] - The company holds over 1,900 authorized patents, supporting the long lifecycle of its innovative drugs [3] Internationalization and Collaborations - The company has transitioned from "product export" to "system capability export" through significant business development collaborations [4] - Notable agreements include a global licensing deal with Merck for a small molecule drug, yielding an upfront payment of $200 million and potential milestone payments of up to $1.77 billion [4] - The partnership with GSK involves the joint development of up to 12 innovative drugs, with an upfront payment of $500 million and a total potential transaction value of approximately $12 billion [4] Market Position and Future Outlook - The successful IPO on the Hong Kong Stock Exchange raised approximately 11.4 billion HKD, marking the largest IPO in the Hong Kong pharmaceutical sector in five years [1][5] - The company is building a leading domestic position while aligning with international standards in pharmaceutical innovation [5] - With ongoing commercialization of innovative drugs and strengthened international collaborations, the company is poised to gain a more significant presence in the global pharmaceutical market [5]

8月20日，恒瑞医药（股票代码：600276.SH；01276.HK）发布2025年半年度报告。报告显示，2025年 上半年，公司实现营业收入157.61亿元，同比增长15.88%；归属于上市公司股东的净利润44.50亿元， 同比增长29.67%；经营性现金流净额达43.00亿元，同比增长41.80%。营收、净利及经营性现金流净额 均创往年同期新高，业绩进入爆发增长期。公司持续加大创新力度，维持较高的研发投入，报告期内公 司研发投入38.71亿元，其中费用化研发投入32.28亿元。 为了增强团队凝聚力及公司核心竞争力，充分发挥长效激励机制，恒瑞医药还同时公告将回购10-20亿 元的股份，用于实行新的员工持股计划，2025年激励规模不超过1400万股。 创新药销售引领业绩增长，对外许可成常态化业务 从业绩角度来看，持续的高强度研发投入加快公司转型升级步伐，公司迈入了创新药丰收期，创新药收 入持续提升。2025年上半年公司创新药销售及许可收入95.61亿元，占公司营业收入比重60.66%，其中 创新药销售收入75.70亿元。瑞维鲁胺、达尔西利、恒格列净等医保内创新药优异的临床数据在实践中 得到广泛验证，临床价值获 ...

来源：环球网 8月20日，恒瑞医药发布2025年半年度报告。报告显示，2025年上半年，该公司实现营业收入157.61亿 元，同比增长15.88%；归属于上市公司股东的净利润44.5亿元，同比增长29.67%；经营性现金流净额达 43亿元，同比增长41.80%。营收、净利及经营性现金流净额均创往年同期新高，业绩进入爆发增长 期。该公司持续加大创新力度，维持较高的研发投入，报告期内公司研发投入38.71亿元，其中费用化 研发投入32.28亿元。 ...

Core Viewpoint - Heng Rui Pharmaceutical demonstrates strong performance with significant revenue growth and profitability, supported by robust R&D capabilities and a solid financial foundation [1][2][10] Financial Performance - As of June 30, 2025, Heng Rui Pharmaceutical achieved operating revenue of 15.761 billion yuan, a year-on-year increase of 15.88% [1] - The net profit attributable to shareholders reached 4.45 billion yuan, reflecting a growth of 29.67% year-on-year [1] - Operating cash flow net amount was 4.3 billion yuan, up 41.8% year-on-year [1] - The company plans to repurchase shares worth 1 to 2 billion yuan for a new employee stock ownership plan [1] R&D Capabilities - Heng Rui Pharmaceutical invested 3.871 billion yuan in R&D during the reporting period, with 3.228 billion yuan classified as expense R&D [2] - The company submitted 255 new patent applications in Greater China and 33 international PCT applications during the reporting period [2] - As of the end of the reporting period, the company held a total of 2,864 invention patent applications in Greater China and 737 PCT patents [2] Profitability and Cash Flow - Heng Rui Pharmaceutical maintained a sales net profit margin above 20% for the past five years, exceeding 28% in the first half of 2025 [3] - The company's monetary funds reached 36.12 billion yuan, a year-on-year increase of 61.89%, providing a strong safety net for high R&D investments [5] Growth Potential - The company has a rich R&D pipeline, with six class 1 innovative drugs approved for market and six new indications approved during the reporting period [6] - There are five listing applications accepted by NMPA, ten clinical trials in phase III, and 22 in phase II [6] - Heng Rui Pharmaceutical's internationalization strategy includes significant licensing agreements, with potential amounts exceeding 10 billion USD in recent years [8][9] Conclusion - Heng Rui Pharmaceutical is positioned as a leader in the innovative drug sector, leveraging its strong technical barriers and self-sustaining capabilities to drive future growth [10]

证券之星消息，8月21日化学制药板块较上一交易日上涨0.09%，*ST苏吴领涨。当日上证指数报收于 3771.1，上涨0.13%。深证成指报收于11919.76，下跌0.06%。化学制药板块个股涨跌见下表： | 代码 | 名称 | 收盘价 | 涨跌幅 | 成交量(手) | 成交额(元) | | | --- | --- | --- | --- | --- | --- | --- | | 600200 | *ST苏吴 | 0.96 | 5.49% | 43.67万 | | 4141.60万 | | 300705 | 九典制药 | 19.87 | 4.97% | 52.35万 | | 10.35 Z | | 300573 | 兴齐眼药 | 67.48 | 4.69% | 22.77万 | | 15.19 Z | | 688506 | 百利天恒 | 324.96 | 4.21% | 1.62万 | | 5.23亿 | | 002940 | 昂利康 | 51.36 | 3.86% | 15.16万 | | 7.69亿 | | 002020 | 京新药业 | 19.52 | 2.90% | 32.05万 | | 6.16 ...