Group 1 - The overall market experienced a decline in the afternoon, but the pharmaceutical and medical sectors showed resilience, with only three out of 31 industries reporting gains [1] - The representative medical ETF (512170) saw a daily increase of 0.62%, with a significant trading volume of 9.82 billion, marking a 128% increase from the previous day and the highest single-day trading volume in over a month and a half [2] - The CXO-related stocks were the main contributors to the sector's performance, with notable gains from companies like Tigermed, which rose by 5.64%, while major player WuXi AppTec experienced a decline [2] Group 2 - For the week of May 19-23, the medical ETF (512170) accumulated a gain of 1.24%, outperforming major indices such as the Shanghai Composite Index, which fell by 0.57% [4] - The market for medical stocks is gradually recovering, with increased trading activity and positive catalysts such as domestic pharmaceutical companies securing overseas contracts [4] - A new "Pharmaceutical ETF" is set to launch on May 26, which will track the CSI Pharmaceutical Index, focusing on chemical drugs, biological drugs, and traditional Chinese medicine, complementing the existing medical ETF [4] Group 3 - The medical and pharmaceutical sectors have been in a prolonged adjustment period since 2021, with current valuations potentially offering high cost-effectiveness for investors [4]

Core Viewpoint - The pharmaceutical sector in China is experiencing significant growth, driven by favorable government policies and increasing international market share, with a notable rise in innovative drug development and exports [1][2]. Group 1: Market Performance - On May 23, 2025, pharmaceutical stocks collectively surged, with sectors like Helicobacter pylori, AI healthcare concepts, and weight-loss drugs rising over 2% [1]. - Hai Chen Pharmaceutical's stock hit a 20% limit up within three minutes of opening, reaching a new high in two and a half years [1]. - Heng Rui Pharmaceutical officially listed on the Hong Kong stock market, with its stock price increasing by approximately 30% post-opening, raising about 9.9 billion HKD through an IPO of 224.5 million shares, marking the largest IPO in the Hong Kong pharmaceutical sector in five years [1]. Group 2: Export and Innovation - In Q1 2025, China's pharmaceutical and healthcare product exports reached 26.632 billion USD, a year-on-year increase of 4.39%, while imports decreased by 4.42% to 20.456 billion USD, indicating a domestic industry upgrade and import substitution effect [1][2]. - The United States remains the largest single market for Chinese pharmaceutical exports, with exports amounting to 4.639 billion USD, a 9.6% increase, primarily driven by raw materials and disposable medical supplies [2]. - By the end of 2024, the number of active innovative drugs developed by Chinese companies reached 3,575, ranking first globally, with domestic products accounting for 42% of newly approved innovative drugs, up from less than 10% in 2015 [2]. Group 3: Future Outlook - Analysts predict that 2025 will be a pivotal year for the pharmaceutical industry in China, marking the beginning of significant revenue growth, profitability for many companies, and an extended valuation cycle due to improvements in payment systems [2].

Core Viewpoint - The pharmaceutical sector in Hong Kong and A-shares has experienced a significant surge, driven by the upcoming 2025 American Society of Clinical Oncology (ASCO) annual meeting where multiple innovative drug companies will showcase their research results. The market is optimistic about the potential of Chinese innovative drugs entering the global market, particularly following the collaboration between 3SBio and Pfizer on a PD-1/VEGF dual antibody [1][3][6]. Group 1: Market Performance - The Hong Kong pharmaceutical sector saw a broad rally, with the Hang Seng Healthcare Index rising over 2%. Notable stock performances included a more than 15% increase for Haijia Medical and over 11% for Green Leaf Pharmaceutical [2]. - In the A-share market, the innovative drug sector also performed strongly, with Haichen Pharmaceutical hitting a 20% limit up and multiple companies like Zhongsheng Pharmaceutical and Huason Pharmaceutical also reaching their limits [3]. Group 2: ASCO Annual Meeting Highlights - Several companies announced their participation in the ASCO annual meeting, including: 1. BeiGene will present 23 abstracts focusing on new data for its product portfolio in hematological and solid tumor treatments [3]. 2. Kelun-Biotech will share results from six clinical studies, including data on its ADC and PD-L1 monoclonal antibody [4]. 3. Ascentage Pharma will present the latest clinical data on APG-2575 and APG-115 [4]. 4. Legend Biotech will disclose updates on its CARVYKTI clinical development project for multiple myeloma [4]. 5. Hengrui Medicine will present updated data on several of its compounds [4]. Group 3: Future Outlook - Analysts predict that 2025 will mark a pivotal year for the pharmaceutical industry, characterized as the "three milestone years": a year of revenue growth post-medical insurance negotiations, a year of profitability for many companies, and a year of valuation uplift due to improved payment conditions [6]. - The Chinese innovative drug sector is transitioning from being followers to becoming significant players in the international market, with a notable increase in the number of innovative drugs developed by Chinese companies, reaching 3,575 by the end of 2024, surpassing the U.S. [6]. Group 4: Investment Recommendations - Analysts recommend focusing on Hong Kong innovative drug stocks due to several factors: 1. The potential for excess returns as companies establish global competitive advantages [7]. 2. The increasing global competitiveness of Chinese innovative drugs, particularly through licensing agreements [7]. 3. Favorable policy and regulatory changes that support the sector [7]. 4. Financial performance indicators show steady revenue growth and relatively safe valuation levels compared to other growth sectors [7].

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Core Viewpoint - JOINN Laboratories (China) Co., Ltd. has announced the further subscription of structured deposit products from Jiangsu Bank, totaling RMB 440 million, which is expected to yield reasonable interest without adversely affecting the company's financial situation [1][5]. Summary by Sections Subscription of Financial Products - The company has subscribed to four structured deposit products from Jiangsu Bank, with the total investment amounting to RMB 440 million [1][4]. - The first product has an investment of RMB 150 million with an expected annual return rate of 0.1%–2.45%, maturing on May 22, 2025 [4]. - The second product involves an investment of RMB 60 million with an expected annual return rate of 1.60%–2.50%, maturing on December 27, 2025 [4]. - The third product has an investment of RMB 200 million with an expected annual return rate of 1.00%–2.56%, maturing on August 26, 2025 [4]. - The fourth product involves an investment of RMB 30 million with an expected annual return rate of 1.50% or 2.45%, maturing on November 23, 2025 [4]. Current Status - As of the announcement date, the company confirmed that all previously subscribed financial products have been redeemed according to their terms, except for the structured deposit products from Jiangsu Bank [5]. - The company believes that the structured deposit products will yield reasonable interest and will not negatively impact its financial condition [5]. Reasoning and Benefits for Subscription - The company aims to utilize excess cash in its capital account without affecting operational liquidity by subscribing to these structured deposit products, which offer higher interest rates compared to regular bank deposits [5]. - The structured deposit products are considered low-risk and are expected to provide better returns than typical commercial bank deposits in China [5].

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不 負 責，對 其 準 確 性 或 完 整 性 亦 不 發 表 任 何 聲 明，並 明 確 表 示，概 不 對 因 本 公 告 全部或任何部分內容而產生或因倚賴該等內容而引致的任何損失承擔任何責 任。 JOINN LABORATORIES (CHINA) CO., LTD. 北京昭衍新藥研究中心股份有限公司 （於 中 華 人 民 共 和 國 註 冊 成 立 的 股 份 有 限 公 司） （股 份 代 號：6127） 須予披露交易 進一步認購金融產品 進一步認購金融產品 董 事 會 謹 此 公 佈，於2025年5月22日（交 易 時 間 後），本 集 團 成 員 公 司 剛 認 購 且 於本公告日期仍未到期的該等江蘇銀行人民幣結構性存款產品合計投資總 額分別為人民幣440,000,000元。 在 認 購 第 四 項 江 蘇 銀 行 人 民 幣 結 構 性 存 款 產 品 之 前，由 於 根 據 上 市 規 則 第 14.07條 就 首 項 江 蘇 銀 行 人 民 幣 結 構 性 存 款 產 品、第 二 項 江 蘇 銀 行 人 民 幣 結 構性存款產 ...

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不 負 責，對 其 準 確 性 或 完 整 性 亦 不 發 表 任 何 聲 明，並 明 確 表 示，概 不 對 因 本 公 告 全部或任何部分內容而產生或因倚賴該等內容而引致的任何損失承擔任何責 任。 JOINN LABORATORIES (CHINA) CO., LTD. 北京昭衍新藥研究中心股份有限公司 （於 中 華 人 民 共 和 國 註 冊 成 立 的 股 份 有 限 公 司） （股 份 代 號：6127） 須予披露交易 進一步認購金融產品 然 而，在 認 購 第 四 項 江 蘇 銀 行 人 民 幣 結 構 性 存 款 產 品 之 後，由 於 根 據 上 市 規 則 第14.07條就認購該等江蘇銀行人民幣結構性存款產品而按合併基準計算 的最高適用百分比率高於5%但低於25%，根 據 上 市 規 則 第14章，認 購 該 等 江 蘇 銀 行 人 民 幣 結 構 性 存 款 產 品 將 構 成 本 公 司 的 一 項 須 予 披 露 交 易，因 此 須 遵守上市規則第14.34條 所 載 的 通 知 及 公 告 規 定。 進一步認購金融產品 ...

昭衍新药于2025年5月13日发布公告，披露关于回购注销部分限制性股票并通知债权人相关事宜。 因激励对象变动触发回购注销 公司于2023年3月30日召开的第四届董事会第二次会议，审议通过了《关于回购注销2019年股票期权与 限制性股票激励计划部分限制性股票的议案》《关于回购注销2021年A股限制性股票激励计划部分限制 性股票的议案》；2023年4月27日召开的第四届董事会第三次会议，再次审议通过《关于回购注销2021 年A股限制性股票激励计划部分限制性股票的议案》。 根据公司《2019年股票期权与限制性股票激励计划（草案）》和《股权激励计划实施考核管理办法》， 1名激励对象因个人原因离职，不符合股权激励计划规定，董事会决定回购注销其持有的限制性股票 0.3293万股。 依据《2021年A股限制性股票激励计划（草案）》和相关考核管理办法，21名激励对象因个人原因离职 或个人业绩考核结果不达标，不符合激励对象规定，董事会决定回购注销其持有的限制性股票3.1108万 股。 2025年1月23日，公司召开2025年第一次临时股东大会，审议通过《关于公司变更注册资本的议案》。 上述回购注销完成后，公司总股本将由535, ...

证券代码：603127 证券简称：昭衍新药 公告编号：2025-020 根据公司《2021年A股限制性股票激励计划（草案）》和《股权激励计划实 施考核管理办法》等相关规定，由于21名激励对象因个人原因离职或个人业绩考 核结果不达标，已不符合公司股权激励计划中有关激励对象的规定，董事会审议 决定回购注销限制性股票3.1108万股。 公司按照规定回购注销2019年限制性股票0.3293万股，回购价格8.21元/股； 回购注销2021年限制性股票3.1108万股，回购价格59.72/股。综上，公司合计回 购注销股票3.4401万股。 公司于2025年1月23日召开的2025年第一次临时股东大会审议通过了《关于 公司变更注册资本的议案》，根据决议，上述回购注销完成后，公司总股本由 公司本次回购注销部分股权激励限制性股票将导致注册资本减少，根据《中 华人民共和国公司法》等相关法律、法规的规定，公司特此通知债权人，债权人 自本公告之日起四十五日内，有权要求公司清偿债务或者提供相应的担保。债权 人未在规定期限内行使上述权利的，本次回购注销将按法定程序继续实施。公司 债权人如要求公司清偿债务或提供相应担保的，应根据《中华人民 ...

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不 負 責，對 其 準 確 性 或 完 整 性 亦 不 發 表 任 何 聲 明，並 明 確 表 示，概 不 對 因 本 公 告 全部或任何部分內容而產生或因倚賴該等內容而引致的任何損失承擔任何責 任。 JOINN LABORATORIES (CHINA) CO., LTD. 北京昭衍新藥研究中心股份有限公司 （於 中 華 人 民 共 和 國 註 冊 成 立 的 股 份 有 限 公 司） （股 份 代 號：6127） 海外監管公告 本公告乃北京昭衍新藥研究中心股份有限公司（「本公司」）根據香港聯合交易 所有限公司證券上市規則第13.10B條 而 作 出。 茲 載 列 本 公 司 於 上 海 證 券 交 易 所 網 站 刊 登 公 告 如 下，僅 供 參 閱。 於 本 公 告 日 期，董 事 會 包 括 主 席 兼 執 行 董 事 馮 宇 霞 女 士、執 行 董 事 高 大 鵬 先 生、孫雲霞女士、羅樨女士及顧靜良先生，及獨立非執行董事張帆先生、楊福全 先 生、陽 昌 雲 先 生 及 應 放 天 先 生。 证券代码：603127 证券简称：昭衍新药 ...