Group 1 - Aibo Medical's stock price dropped by 5.02% to 72.28 CNY per share, with a trading volume of 239 million CNY and a turnover rate of 1.71%, resulting in a total market capitalization of 13.979 billion CNY [1] - Aibo Medical, established on April 21, 2010, and listed on July 29, 2020, specializes in the research, production, sales, and related services of ophthalmic medical devices [1] - The company's main revenue sources include intraocular lenses (43.86%), contact lenses (30.06%), orthokeratology lenses (15.14%), myopia control products (6.01%), other surgical products (2.37%), vision care products (1.62%), and other income (0.95%) [1] Group 2 - Huabao Fund's Huabao CSI Medical ETF (512170) is among the top ten circulating shareholders of Aibo Medical, having increased its holdings by 231,800 shares in Q2, totaling 4.4169 million shares, which represents 2.33% of the circulating shares [2] - The estimated floating loss for Huabao CSI Medical ETF today is approximately 16.8725 million CNY [2] - The fund was established on May 20, 2019, with a current size of 26.147 billion CNY, yielding 18.43% year-to-date and 42.82% over the past year, ranking 2736 out of 4220 and 2434 out of 3814 in its category, respectively [2]

Summary of Key Points from the Conference Call Industry Overview - The pharmaceutical industry in China is experiencing enhanced innovation capabilities, with leading companies showing growth rates surpassing the global average, indicating an increase in global competitiveness [1][2] - Despite recent market fluctuations, the fundamentals of the pharmaceutical industry remain robust, with reasonable valuations and no signs of bubbles [1][3][4] Core Insights and Arguments - The overall valuation of the pharmaceutical sector is deemed reasonable, with potential growth for innovative drug companies projected at 50-100% over the next three years [1][4] - The medical device, CRO (Contract Research Organization), consumer healthcare, and traditional Chinese medicine sectors also show relatively low valuations, indicating manageable risks [1][4] - The current allocation in the pharmaceutical sector is at a historical low, suggesting room for improvement in future investments [5] - The innovative drug sector's logic remains unchanged, with active business development (BD) activities expected, particularly in areas like PD-L1 Plus, ADC, and dual antibodies [1][7] Market Performance and Trends - The pharmaceutical sector has shown significant performance this year, with the Hong Kong stock index rising nearly 100% and the A-share market increasing by approximately 40-50% [3][5] - The recovery of the innovative drug sector is expected to lead to nonlinear growth, with many companies in the sector having a PEG ratio of less than 1, indicating accelerated earnings growth [6][7] - The medical device sector is in a mild recovery phase, with procurement pressures easing and opportunities for domestic companies to gain market share through competitive pricing [3][24][25] Investment Opportunities - Innovative drugs are highlighted as the primary investment focus due to their potential for significant earnings growth and market interest following recent interest rate cuts [6][7] - The medical device sector is also seen as a stable investment opportunity, with leading companies showing signs of recovery in their financial performance [6][7] - Consumer healthcare and traditional Chinese medicine are currently more focused on individual stock selection, with potential for recovery in the latter half of the year [6][35] Company-Specific Insights - Key companies with strong growth potential include Heng Rui, BeiGene, and Innovent Biologics, with expectations of exceeding profit forecasts [7][10] - The performance of companies like WuXi AppTec and WuXi Biologics is also noted, with a focus on their recovery and growth potential in the coming years [19][20] Policy and Regulatory Environment - Recent policy changes, such as the optimization of centralized procurement, are expected to positively impact the pharmaceutical sector, providing better financial and profit margins for innovative drug companies [9][24] - The adjustment of the essential drug list is anticipated to have significant implications for the traditional Chinese medicine sector, with expectations for clearer guidelines in the near future [45] Risks and Challenges - While there are no significant risks currently identified in the industry, geopolitical factors, particularly U.S.-China relations, could introduce uncertainties [23] - The medical device sector faces ongoing pricing pressures, particularly in the context of centralized procurement, which could impact profitability [25][29] Conclusion - The pharmaceutical industry in China is positioned for growth, with innovative drugs and medical devices leading the way. The current market environment presents numerous investment opportunities, particularly for companies demonstrating strong fundamentals and growth potential.

Core Viewpoint - The Chinese innovative drug industry is gradually catching up with Europe and the United States in terms of technology, with some targets and technical pathways already leading globally. The number and value of new drugs authorized for overseas markets continue to increase, leading to world-class pricing and non-linear investment elasticity. The domestic market is experiencing strong growth in demand, with domestic new drug sales continuing to rise, and several innovative pharmaceutical companies have turned losses into profits, entering a stable growth phase [2]. Group 1: Innovative Drugs - The innovative drug sector is witnessing a significant increase in sales driven by strong domestic demand, with a number of innovative companies achieving profitability [2]. - The trend of domestic innovative drugs going overseas is accelerating, with increasing numbers and values of new drug authorizations [2]. - The pricing power of innovative drugs is improving, reflecting the global competitiveness of Chinese pharmaceutical companies [2]. Group 2: High-Value Medical Consumables - The orthopedic sector is expected to see mild price reductions due to continued domestic substitution and accelerated overseas business progress [2]. - The neurosurgery and neurointervention fields are experiencing stable growth post-collection, with new products being launched [2]. - The high-value consumables market is expected to benefit from ongoing domestic replacement and the introduction of new products [2]. Group 3: Medical Devices - The medical device sector is seeing a recovery in bidding prices, with ongoing high-speed growth in bidding data this year [2]. - Companies are entering a phase of inventory reduction, with performance expected to improve in the second half of the year [2]. - The low-value consumables sector is experiencing product upgrades and accelerated expansion into overseas markets [2]. Group 4: Blood Products - The supply side of the blood products industry is concentrating on central state-owned enterprises, gradually clearing the competitive landscape [2]. - The demand side is expected to see continuous upgrades to new products, with industry sentiment gradually improving [2]. Group 5: API (Active Pharmaceutical Ingredients) - The API sector is benefiting from the end of a capital expenditure peak, with three growth logic points driving upward trends: new high-end market products, integrated consolidation and overseas expansion, and cost-leading CDMO [2]. - Leading companies in the API sector are expected to see explosive growth in revenue and profits [2]. Group 6: CXO (Contract Research Organization) - The CXO sector is witnessing a recovery in A+H financing activity, with multiple significant business developments enhancing market confidence [2]. - The focus is on optimizing the supply-side landscape and increasing market share for leading CRO companies [2]. Group 7: Traditional Chinese Medicine and Retail Pharmacy - The traditional Chinese medicine sector is showing signs of recovery, with friendly pricing for new drugs and ongoing observation of collection progress [2]. - The retail pharmacy sector is influenced by the pace of supply-side clearing and business model upgrades, with expectations of increased store closures in the second half of 2025 [2]. Group 8: Research and Development Services - The domestic innovative drug business development is heating up, likely driving downstream demand recovery [2]. - The overseas market presents significant growth opportunities for domestic companies, leveraging cost-effectiveness and service differentiation [2].

Core Viewpoint - The company has not yet applied its main business product materials in the robotics field and is considering future commercialization and collaboration in related areas based on R&D and market conditions [1] Group 1: Business Operations - The company has developed multiple ophthalmic medical device products based on its existing technology platform, but none have entered the smart glasses market as of now [1] - The company is actively pursuing mergers and acquisitions of quality resources through its own funds and industrial funds, planning to evaluate these based on market research results and technical feasibility [1] Group 2: Market Position - Currently, there is no latest authoritative third-party statistical data on the company's domestic market share for its main business products [1] - In the field of artificial lenses, the company's product volume ranks first according to data disclosed by national procurement [1]

Core Viewpoint - The company has not yet applied its main business product materials in the robotics field and is considering future commercialization and collaboration in related areas based on R&D and market conditions [1] Group 1 - The company has developed multiple ophthalmic medical device products based on its existing technology platform, but none have entered the smart glasses market as of now [1] - The company currently lacks the latest authoritative third-party statistics on its domestic market share for its main business products [1] - In the intraocular lens sector, the company's product volume ranks first according to data disclosed by national procurement [1] Group 2 - The company is continuously advancing the integration of quality resources through its own funds and industrial funds [1] - Future merger and acquisition plans will be evaluated based on market research results, technical feasibility, and other multidimensional factors, with strict adherence to regulatory disclosure requirements [1]

Core Viewpoint - The company has not yet applied its main business product materials in the robotics field and is considering future commercialization and collaboration based on research and market conditions [1] Group 1 - The company has developed multiple ophthalmic medical device products relying on its existing technology platform [1] - Currently, the products produced and sold by the company do not involve the smart glasses sector [1] - Future considerations for commercialization and collaboration in related fields will depend on research and market conditions [1]

Core Viewpoint - The Chinese innovative drug industry is gradually catching up with Europe and the United States in terms of technology, with some targets and technical pathways already leading globally. The number and value of new drugs authorized for overseas markets continue to increase, leading to world-class pricing and non-linear investment elasticity. The domestic market is experiencing strong growth in demand, with domestic new drug sales continuing to rise, and several innovative pharmaceutical companies have turned losses into profits, entering a stable growth phase [2]. Group 1: Innovative Drugs - The innovative drug sector is witnessing a significant increase in sales driven by strong domestic demand, with a number of innovative companies achieving profitability [2]. - The trend of domestic innovative drugs going overseas is accelerating, with increasing numbers and values of new drug authorizations [2]. - The industry is positioned for a "Davis double" effect, where both performance and valuation are expected to improve [2]. Group 2: High-Value Medical Consumables - The orthopedic sector is expected to see mild price reductions, while domestic replacements continue to grow, and overseas business progresses rapidly [2]. - The neurosurgery and neurointervention fields are stabilizing after centralized procurement, with new products expected to contribute to growth [2]. Group 3: Medical Devices - The medical device sector is experiencing a high-speed growth in bidding data, with companies entering a destocking phase, which is expected to improve performance in the second half of the year [2]. - The low-value consumables sector is seeing continuous product upgrades and accelerated expansion into overseas markets [2]. Group 4: Blood Products - The supply side of the blood products industry is increasingly concentrated among state-owned enterprises, leading to a clearer competitive landscape [2]. - The demand side is expected to upgrade towards new products, gradually improving the industry's overall health [2]. Group 5: API (Active Pharmaceutical Ingredients) - The industry is at an upward turning point due to the end of a capital expenditure peak, combined with three growth drivers: new high-end market products, integrated consolidation and overseas expansion, and cost-leading CDMO [2]. - Leading companies are expected to see explosive growth in revenue and profits in the medium term [2]. Group 6: CXO (Contract Research Organization) - The CXO sector is seeing a revival in A+H financing activity, with multiple significant business developments enhancing market confidence [2]. - The focus is on optimizing the supply-side landscape and increasing market share for leading CRO companies [2]. Group 7: Traditional Chinese Medicine and Retail Pharmacy - The traditional Chinese medicine sector is showing signs of recovery, with friendly pricing for new drugs, while the retail pharmacy sector is influenced by supply-side adjustments and business model upgrades [2]. - The performance of offline pharmacies is expected to improve in the second half of 2025, with leading chains like YaoXingTang making progress in store upgrades [2]. Group 8: Research Reports - A series of in-depth research reports on various companies and sectors within the pharmaceutical and medical device industries have been published, highlighting their growth potential and market positioning [3][4].

Investment Rating - The report maintains a "Recommended" rating for the company, indicating an expectation to outperform the benchmark index by 10%-20% over the next six months [22]. Core Insights - The company reported a revenue of 787 million yuan for the first half of 2025, representing a year-on-year growth of 14.72%, with a net profit of 213 million yuan, up 2.53% [2]. - The high-end intraocular lens segment is experiencing rapid growth, and the company is accelerating its overseas market expansion [2][6]. - The company has a strong pipeline of innovative products, with several projects in the registration phase and expected to launch soon [6]. Financial Performance - For the first half of 2025, the company achieved a revenue of 787 million yuan, with a net profit of 213 million yuan, and a non-recurring net profit of 204 million yuan [2]. - The revenue for Q2 2025 was 430 million yuan, reflecting a year-on-year increase of 14.44%, while the net profit for the same period was 121 million yuan, up 14.85% [2]. - The company forecasts total revenue of 1,795 million yuan for 2025, with a year-on-year growth rate of 27.3% [7]. Business Segmentation - The high-end intraocular lens revenue reached 364 million yuan in H1 2025, growing by 9.70%, with artificial lens products contributing 345 million yuan, up 8.23% [6]. - The company’s near-sightedness prevention segment generated 166 million yuan, with a growth of 8.28%, while vision care revenue was 249 million yuan, increasing by 27.43% [6]. - Domestic revenue was 744 million yuan, up 12.37%, while overseas revenue surged by 80.10% to 43 million yuan, indicating a strong international market strategy [6]. Valuation and Price Target - The report sets a target price of 100 yuan, based on a DCF model that values the company at approximately 194 billion yuan [3][6]. - The expected earnings per share (EPS) for 2025 is projected at 2.40 yuan, with a price-to-earnings (P/E) ratio of 32 [7].

Investment Rating - The report assigns a "Buy" rating to the company [1][4][6] Core Views - The company reported a revenue of 787 million yuan in H1 2025, representing a year-on-year increase of 14.72%, and a net profit attributable to shareholders of 213 million yuan, up by 2.53% [1] - The growth in high-end crystals and soft lenses is accelerating, with a strong product pipeline continuing to advance [1][3] - The company is positioned as a leading domestic ophthalmic consumables manufacturer, benefiting from rapid growth in high-end consumables and capacity expansion in soft lenses [4] Financial Performance Summary - Revenue and Profit: In H1 2025, the company achieved a revenue of 787 million yuan (+14.72%) and a net profit of 213 million yuan (+2.53%) [1] - Gross Margin: The gross margin for H1 2025 was 65.25%, reflecting a decrease of 3.98 percentage points due to the dilution from the colored lens business [2] - Profitability Metrics: The net profit margin was 26.30% (-2.75 percentage points), and the attributable net profit margin was 27.11% (-3.22 percentage points) [2] Business Segments Performance - Artificial Lens: Revenue from the artificial lens business was 345 million yuan (+8.23%) with a gross margin of 86.42% [3] - Orthokeratology Lens: Revenue from orthokeratology lenses was 119 million yuan (+5.63%) with a gross margin of 84.76% [3] - Other Myopia Control Products: Revenue from other myopia control products was 47 million yuan (+15.58%) with a gross margin of 69.65% [3] - Contact Lens: Revenue from contact lenses was 236 million yuan (+28.89%) with a gross margin of 27.76% [3] Product Pipeline and R&D - The company has received approvals for several products, including the "Long Crystal" artificial lens and silicone hydrogel soft lenses [4] - Ongoing R&D includes EDoF artificial lenses and various types of hyaluronic acid for filling, with several products in clinical trials [4] Earnings Forecast and Valuation - The company is expected to generate revenues of 1.738 billion yuan, 2.229 billion yuan, and 2.751 billion yuan for the years 2025, 2026, and 2027, respectively [4] - Projected net profits for the same years are 454 million yuan, 574 million yuan, and 720 million yuan [4] - Corresponding P/E ratios for 2025, 2026, and 2027 are estimated at 33X, 26X, and 21X, respectively [4]

中国银河证券股份有限公司关于 爱博诺德（北京）医疗科技股份有限公司 2025 年半年度持续督导跟踪报告 根据《证券发行上市保荐业务管理办法》《上海证券交易所科创板股票上市 规则》和《上海证券交易所上市公司自律监管指引第 11 号——持续督导（2025 年 3 月修订）》等有关法律、法规的规定，中国银河证券股份有限公司（以下简 称"保荐人"）作为正在履行爱博诺德（北京）医疗科技股份有限公司（以下简 称"爱博医疗""公司"）持续督导工作的保荐机构，出具本持续督导半年度跟 踪报告。 一、持续督导工作概述 1、保荐人制定了持续督导工作制度，制定了相应的工作计划，明确了现场 检查的工作要求。 2、保荐人已与公司签订保荐协议，该协议已明确了双方在持续督导期间的 权利义务，并报上海证券交易所备案。 3、本持续督导期间，保荐人通过与公司的日常沟通、现场回访等方式开展 持续督导工作。 4、本持续督导期间，保荐人根据相关法规和规范性文件的要求履行持续督 导职责，具体内容包括： （1）查阅公司章程、三会议事规则等公司治理制度、三会会议材料；（2） 查阅公司财务管理、会计核算和内部审计等内部控制制度；（3）查阅公司与其 关联方的资金 ...