本报讯 （记者金婉霞）8月28日，上海皓元医药股份有限公司（以下简称"皓元医药"）发布2025年半年 报。2025年上半年，公司实现营业收入13.11亿元，同比增长24.20%；其中，境外收入达5.6亿元，同比 增长39.78%。公司实现归母净利润1.52亿元，同比增长115.55%；毛利率达49.1%，同比提升3.7个百分 点。2025年上半年，公司资产总额升至58.43亿元，经营业绩持续稳步增长。 皓元医药表示，2025年上半年，公司秉持长期主义理念，始终紧扣"产业化、全球化、品牌化"核心战 略，以客户价值为导向，聚焦主业，积极创新，逐步完善治理体系，不断吸纳人才，通过深化"前端 +后端"一体化协同，全面推进提质增效，为实现全年战略目标奠定坚实基础。 聚焦三大引擎业务 筑牢"研发+生产"一体化服务基石 皓元医药扎根生物医药领域近二十年，始终坚持自主科技创新，是国内小分子药物"研发+生产"领域为 数不多的前端、后端一体化平台型高新技术企业。皓元医药依托技术、产品与团队优势，聚焦"工具化 合物和生化试剂""分子砌块""原料药和中间体、制剂"三大引擎业务，为全球超1.3万家合作伙伴提供服 务，持续巩固细分领域领 ...

Market Overview - The medical services sector rose by 3.64% on August 29, with the leading stock being Puris [1] - The Shanghai Composite Index closed at 3857.93, up 0.37%, while the Shenzhen Component Index closed at 12696.15, up 0.99% [1] Top Gainers in Medical Services - Zenggansi (301257) closed at 43.54, up 20.01% with a trading volume of 64,900 shares and a turnover of 278 million [1] - Haoyuan Pharmaceutical (688131) closed at 68.48, up 13.70% with a trading volume of 189,200 shares and a turnover of 1.256 billion [1] - Bidai Pharmaceutical (688073) closed at 67.11, up 10.43% with a trading volume of 28,300 shares and a turnover of 182 million [1] - Meidi Xi (688202) closed at 64.21, up 8.96% with a trading volume of 124,400 shares and a turnover of 784 million [1] - WuXi AppTec (603259) closed at 103.30, up 7.95% with a trading volume of 1,016,600 shares and a turnover of 10.18 billion [1] Top Losers in Medical Services - Digital Human (835670) closed at 17.54, down 6.20% with a trading volume of 127,200 shares and a turnover of 227 million [2] - Puri Eye Hospital (301239) closed at 40.78, down 4.63% with a trading volume of 49,600 shares and a turnover of 203 million [2] - Yingkang Life (300143) closed at 10.64, down 3.45% with a trading volume of 230,300 shares and a turnover of 250 million [2] Capital Flow in Medical Services - The medical services sector saw a net inflow of 1.259 billion from institutional investors, while retail investors experienced a net outflow of 446 million [2][3] - Major stocks like WuXi AppTec had a net inflow of 1.269 billion from institutional investors, while it faced a net outflow of 741 million from retail investors [3]

Group 1 - The A-share market saw a significant rise in CRO concept stocks, with notable increases in share prices for several companies [1] - Haoyuan Pharmaceutical experienced a rise of over 15%, while Chengdu XianDao and MeidiXi saw increases of over 11% and 10% respectively [1] - Other companies such as Bid Pharma, Boteng Co., and WuXi AppTec also reported gains exceeding 7% [1] Group 2 - The following table summarizes the performance of key CRO stocks, including their percentage increase, total market capitalization, and year-to-date performance [2] - Haoyuan Pharmaceutical: +15.19%, Market Cap: 14.7 billion, YTD: +95.07% - Chengdu XianDao: +11.02%, Market Cap: 10.7 billion, YTD: +116.70% - MeidiXi: +10.54%, Market Cap: 8.75 billion, YTD: +115.91% - Bid Pharma: +8.39%, Market Cap: 5.99 billion, YTD: +36.61% - Boteng Co.: +7.51%, Market Cap: 13.6 billion, YTD: +58.02% - WuXi AppTec: +7.43%, Market Cap: 303.4 billion, YTD: +90.82% - Sunshine Nuohe: +6.32%, Market Cap: 8.46 billion, YTD: +100.86% - Baicheng Pharmaceutical: +4.97%, Market Cap: 6.29 billion, YTD: +51.90% - Kailai Ying: +4.49%, Market Cap: 39 billion, YTD: +43.98% - NuoSiGe: +4.35%, Market Cap: 5.19 billion, YTD: +7.82% [2]

Group 1 - The A-share CRO (Contract Research Organization) sector experienced a significant rally on August 29, with notable stock price increases [1] - Haoyuan Pharmaceutical surged over 14%, while Medices and Chengdu Xian Dao saw increases of over 10% and 9% respectively [1] - Other companies such as Pruis and Boteng Co., along with Inno Laser, also showed positive performance in the market [1]

Core Viewpoint - The innovative drug concept has seen a resurgence, with Haoyuan Pharmaceutical rising over 15%, and both Kangchen Pharmaceutical and Huahai Pharmaceutical hitting the daily limit up [1] Company Summary - Haoyuan Pharmaceutical experienced a significant increase in stock price, rising more than 15% [1] - Kangchen Pharmaceutical and Huahai Pharmaceutical both reached the daily trading limit, indicating strong market interest and investor confidence [1] Industry Summary - The innovative drug sector is witnessing renewed interest, reflected in the substantial stock price movements of key players [1]

8月29日，生物医药ETF（159859）盘中走强，截至发稿涨1.16%，成交额超9400万元，居同标的第 一。成分股中，荣昌生物涨超4%，爱美客、甘李药业、药明康德等跟涨。 华源证券认为，2025年，医药行业已具备多重积极发展因素，基本完成了新旧增长动能转换（创新替代 仿制，出海能力提升），创新药打开中国医药企业增长新曲线。 Wind金融终端数据显示，生物医药ETF（159859）连续三个交易日获资金净流入，累计"吸金"超6100 万元。 万和证券表示，整体来看，指数短线或将面临震荡，但板块轮动表现，不少低位滞涨的品种开启补涨走 势说明资金高低切换迹象逐步加强，市场延续结构性行情，未来降息叠加经济复苏预期，顺周期等方向 仍可重点关注。 生物医药ETF（159859）紧密跟踪国证生物医药指数（399441.SZ），该指数布局均衡，覆盖A股创新 药，CXO，疫苗，血制品多个方向。生物医药ETF（159859）为同标的规模最大、流动性最好的产品。 该ETF还配备了联接基金（A：011040，C：011041）。 （本文机构观点来自持牌证券机构，不构成任何投资建议，亦不代表平台观点，请投资人独立判断和决 策。） 此 ...

Core Viewpoint - The innovative pharmaceutical stocks experienced a significant rebound, with Huahai Pharmaceutical and Kangchen Pharmaceutical both hitting the daily limit up, indicating strong market interest and investor confidence in the sector [1] Industry Summary - The National Medical Products Administration of China reported that the country's pharmaceutical industry ranks second globally, with approximately 30% of the world's innovative drugs currently under research [1] - Since the beginning of the 14th Five-Year Plan, a total of 387 pediatric drugs and 147 rare disease drugs have been approved for market, effectively addressing the medication needs of key populations [1] Company Summary - Huahai Pharmaceutical and Kangchen Pharmaceutical both reached the daily limit up, reflecting positive market sentiment towards their stock performance [1] - Other companies such as Puris, Duolai Pharmaceutical, Haoyuan Pharmaceutical, Huana Pharmaceutical, Medisi, Lifang Pharmaceutical, and Guangshengtang also saw stock increases, with some rising over 5% [1]

| 证券代码：688131 | 证券简称：皓元医药 公告编号：2025-104 | | --- | --- | | 转债代码：118051 | 转债简称：皓元转债 | 上海皓元医药股份有限公司 关于向不特定对象发行可转换公司债券募投项目调 整部分实施地点及延期的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈 述或者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 上海皓元医药股份有限公司（以下简称"皓元医药"或"公司"）于2025 年8月26日召开第四届董事会审计委员会第五次会议、于2025年8月27日召开第 四届董事会第十一次会议，审议并通过了《关于向不特定对象发行可转换公司 债券募投项目调整部分实施地点及延期的议案》，同意公司将向不特定对象发 行可转换公司债券募集资金投资项目（以下简称"募投项目"）"高端医药中间 体及原料药CDMO产业化项目（一期）"（以下简称"CDMO项目"）部分车 间、公用工程及辅助设施的实施地点在原厂区内进行调整，并将该项目达到预 定可使用状态的时间延期至2029年6月。公司保荐机构民生证券股份有限公司 （以下简称"保荐机构"）对该事项出具了无 ...

格隆汇8月28日丨皓元医药(688131.SH)发布中报，2025上半年实现营业总收入13.11亿元，同比增长 24.2%；归属母公司股东净利润1.52亿元，同比增长115.55%；基本每股收益为0.72元。此外，拟对全体 股东每10股派发现金红利0.8元(含税)。 ...

Market Overview - The recombinant protein sector experienced a decline of 1.01%, ranking among the top losers in concept sectors as of the market close on August 28 [1] - Notable declines within the sector included companies such as Aladdin, Bory Pharmaceutical, and Zhongyuan Union, while Chengdu XianDao, Dezhan Health, and Betta Pharmaceuticals saw increases of 7.44%, 2.38%, and 2.02% respectively [1] Concept Sector Performance - The top-performing concept sectors included Copper Cable High-Speed Connection (+5.61%), Co-Packaged Optics (+5.13%), and F5G Concept (+5.12%), while the recombinant protein sector was among the laggards with a decline of 1.01% [2] Capital Flow Analysis - The recombinant protein sector faced a net outflow of 1.348 billion yuan, with 41 stocks experiencing net outflows, and 6 stocks seeing outflows exceeding 50 million yuan [2] - Bory Pharmaceutical led the outflows with a net outflow of 548 million yuan, followed by Zhifei Biological, Hualan Biological, and Zhongyuan Union with net outflows of 149 million yuan, 88.91 million yuan, and 77.72 million yuan respectively [2] Individual Stock Performance - Bory Pharmaceutical reported a decline of 6.63% with a turnover rate of 5.33% and a net outflow of 547.71 million yuan [3] - Chengdu XianDao was the standout performer in the sector, increasing by 7.44% despite a net outflow of 203.74 million yuan [3] - Other notable stocks with significant net inflows included Dezhan Health (+2.38%) with a net inflow of 46.14 million yuan, Haoyuan Pharmaceutical (+1.82%) with a net inflow of 18.75 million yuan, and Maimai Biological (+1.82%) with a net inflow of 18.75 million yuan [4]