Patients treated with remibrutinib experienced improvements in weekly urticaria activity scores (UAS7) observed as early as Week 1 and sustained to 1 year (Week 52)1 Remibrutinib, an oral Bruton's tyrosine kinase inhibitor, demonstrated a favorable and consistent safety profile up to 1 year, including balanced liver function tests versus placebo1 Novartis intends to submit remibrutinib for approval in chronic spontaneous urticaria (CSU) to global health authorities starting in H2 2024, and continues to inve ...

Novartis (NVS) announced results from the six-month, double-blind trial period of the late-stage APPEAR- C3G study of Fabhalta. Fabhalta, an oral Factor B inhibitor of the alternative complement pathway, is being investigated in adult patients with C3 glomerulopathy (C3G). APPEAR-C3G is a phase III multicenter, randomized, double-blind, parallel-group, placebo-controlled study to evaluate the efficacy and safety of twice-daily oral Fabhalta (200 mg) in C3G patients. The study comprises a six-month double-bl ...

Scientists working in a laboratory. Monty Rakusen/DigitalVision via Getty Images In this life, the truth is that nothing lasts forever. Milk and eggs have an expiration date. Our lives all expire. Businesses cease to exist or are rolled up into other businesses. Think Japan's Kongo Gumi construction company, which was founded in 578 AD. In 2006, even it was liquidated. Technically, it still operates today as part of the subsidiary of Takamatsu Construction Group. But it is no longer the standalone company t ...

Basel, May 25, 2024 – Novartis today presented results from a pre-specified interim analysis of the Phase III ALIGN study of atrasentan, an investigational oral selective endothelin A (ETA) receptor antagonist, in patients with IgA nephropathy (IgAN)1. Patients treated with atrasentan, in addition to supportive care (maximally tolerated and stable dose of a renin-angiotensin system [RAS] inhibitor), achieved a 36.1% (p<0.0001) reduction in proteinuria (as measured by 24-hour urine protein to creatinine rati ...

EAST HANOVER, N.J., May 25, 2024 /PRNewswire/ -- Novartis today presented results from the 6-month, double-blind period of the Phase III APPEAR-C3G study of Fabhalta® (iptacopan) at the late-breaking clinical trials session of the European Renal Association (ERA) Congress1. Patients treated with Fabhalta in addition to supportive care achieved a 35.1% (p=0.0014) reduction in proteinuria (as measured by 24-hour urine protein to creatinine ratio [UPCR]) at 6 months when compared to placebo on top of supportiv ...

New York, USA, May 16, 2024 (GLOBE NEWSWIRE) -- Motor Neuron Disease Clinical Trial Pipeline Appears Robust With 120+ Key Pharma Companies Actively Working in the Therapeutics Segment | DelveInsight Diagnosing motor neuron diseases often presents challenges as there are no definitive tests in many cases. Motor neuron disease symptoms can vary widely among individuals and, in the early stages, may resemble those of other illnesses, complicating diagnosis. However, specific gene tests are available for condit ...

The dividend is just one reason to buy these stocks.There are many reasons to invest in excellent dividend stocks. Such investments are often worth the trouble regardless of whether you're investing for the dividend, or for making capital gains from the robust business (always a laudable goal). But here's the common thread that runs through outstanding dividend stocks: Companies that grow their dividend payouts over extended periods time all have solid fundamentals.The obvious corollary is, not every divide ...

A double beat on the latest quarterly results and raised guidance made investors happy.Scooting past analyst estimates for its latest quarter gave Novartis (NVS 2.27%) a lift on Tuesday. Investors like what they heard about the global healthcare company's inaugural earnings release for 2024, and rewarded Novartis with a more than 2% lift in its stock price today. The shares did better than the S&P 500 index, which had a relatively good trading session with a 1.2% gain.Double beats in the first quarterIn its ...

About this content About Emily Jarvie Emily began her career as a political journalist for Australian Community Media in Hobart, Tasmania. After she relocated to Toronto, Canada, she reported on business, legal, and scientific developments in the emerging psychedelics sector before joining Proactive in 2022. She brings a strong journalism background with her work featured in newspapers, magazines, and digital publications across Australia, Europe, and North America, including The Examiner, The Advocate, ...

Key TakeawaysNovartis beat first-quarter forecasts for profit and sales on rising demand for its blockbuster drugs.Revenue from the Swiss-based pharmaceutical firm's top-selling medicines, Entresto and Cosentyx, climbed 36% and 25%, respectively.Novartis also boosted its full-year sales and core operating income guidance. American depositary receipts (ADRs) of Novartis (NVS) rose in intraday trading Tuesday as the Swiss-based pharmaceutical firm reported better-than-expected first-quarter results and booste ...