Workflow
青蒿素
icon
Search documents
焦点访谈 | 李博洋:细胞“打工”造万物 解码生物制造的产业潜能
Xin Lang Cai Jing· 2026-01-08 11:43
主持和参与国家级课题3项、省部级课题40余项,国际合作项目5项,联合出版专著15部,在国内外期刊发表文章50余篇,获日本废弃物学会优秀成果奖1 次、年度优秀论文奖1次。参与起草《促消费扩内需对策研究报告》《消费品工业"三品"专项行动实施效果评估报告》《关于开展工业产品生态设计的指 导意见》《中国降低荧光灯含汞量路线图》等多项重要技术报告和政策规划文件。 赛迪智库·消费品工业研究所 李博洋 消费品工业研究所 所长 长期从事消费品工业高质量发展、工业产品绿色设计、工业绿色低碳转型等领域的管理政策研究、产业规划制定与战略决策咨询等工作。 生物制造,是"十五五"规划《建议》提出的六大未来产业之一。什么是生物制造?它又能干什么?比如细胞,它无时无刻不在进行新陈代谢,吃下食物, 然后把代谢的产物排出体外,这是大自然的精妙设计。但今天,人类已经开始掌握其中的奥秘,把它变成了工业生产的一个环节。生物制造,就是科学家 们把这些微小生物体的内部,变成一个小工厂,吃下原材料,生产出我们需要的产品,比如把秸秆变成环保材料,把二氧化碳变成饲料蛋白,把贝壳做成 牙齿修复材料。这不是一个变魔法的过程,而是以生物工程、基因工程等科学技术为源 ...
焦点访谈|生物制造,万亿赛道如何跑出“加速度”?
Yang Shi Wang· 2025-12-26 13:28
央视网消息(焦点访谈):生物制造,是"十五五"规划《建议》提出的六大未来产业之一。什么是生物制造?它又能干什么?比如细胞,它无时无刻不 在进行新陈代谢,吃下食物,然后把代谢的产物排出体外。这是大自然的精妙设计。但今天,人类已经开始掌握其中的奥秘,把它变成了工业生产的一个环 节。生物制造,就是科学家们把这些微小生物体的内部,变成一个小工厂,吃下原材料,生产出我们需要的产品,比如把秸秆变成环保材料,把二氧化碳变 成饲料蛋白,把贝壳做成牙齿修复材料。这不是一个变魔法的过程,而是以生物工程、基因工程等科学技术为源头到工业化生产的一个完整产业链。 衣服、药品、吸管......这些东西看起来似乎有些普通,但这些产品却有些不同,它们的生产都属于一个大产业——生物制造。 这里最重要的生产车间就是一个个大发酵罐,里面不断搅动的液体,满是正在工作的细胞。 在企业实验室里,借助显微镜能更近一步看到每个正在生产的细胞到底是什么样的。 微构工场副总裁欧阳鹏飞:"这个细胞可以看到里面有五个不同的小区域,每个小区域就代表一个PHA的颗粒,里面不同的颗粒挤在一起,填满了整个 细胞,这就代表着一个细胞已经积累了非常非常多的PHA。我们的终极目 ...
广州南方学院成立青蒿创新研究中心
Nan Fang Du Shi Bao· 2025-12-16 10:58
南都讯 日前,广州南方学院举行青蒿创新研究中心揭牌仪式暨产教融合人才培养研讨会。据悉,此次 青蒿创新研究中心的成立,是广州南方学院深化产教融合、响应"中医药传承创新发展"国家战略的关键 举措。研究中心汇聚学校、企业、政府与研究机构等多方力量,致力于通过产学研协同,推动青蒿领域 的科技创新、产业升级与人才培养,为探索产学研深度融合的新路径、形成可推广的实践经验作出积极 贡献。 从化区卫健局副局长张科指出,青蒿创新研究中心的成立,是对接"双百行动"、服务"百千万工程"的关 键落子。从化区卫健局将积极发挥桥梁作用,推动中心与区属医疗机构的深度合作,让科研成果优先在 从化转化应用,让中医药红利惠及百姓。 在揭牌环节,学校科研处处长严五胤教授宣读中心成立文件,王新华教授、宋健平教授受聘为中心学术 顾问。与会嘉宾共同为研究中心揭牌。 专题研讨环节,专家学者围绕青蒿研究展开深入交流。广州医科大学原校长王新华教授回顾青蒿素研发 历程,广州中医药大学宋健平教授介绍疟疾防治中国方案,广东新南方集团青蒿药业潘隆华总经理分享 产业链布局,广东省科学院生态环境与土壤研究所副所长刘同旭研究员阐述种植生态机制,国家农科中 心部长胡玉伟研究 ...
超越青蒿素,克服耐药性!首个非青蒿素抗疟疾药物即将上市
生物世界· 2025-11-16 03:34
Core Viewpoint - The article highlights the significant advancements in malaria treatment, particularly focusing on the development of a new drug, Ganaplacide–Lumefantrine (GanLum), by Novartis, which shows promise against drug-resistant malaria strains [8][10]. Group 1: Historical Context and Current Situation - In 1972, Chinese scientists, led by Tu Youyou, extracted artemisinin from sweet wormwood, significantly reducing malaria mortality rates and earning Tu the Nobel Prize in 2015 [2]. - The compound artemisinin led to the development of artemether-lumefantrine, marketed as Coartem, which became a first-line treatment for malaria and has saved millions of lives since its approval in 1999 [3][5]. - Malaria, caused by Plasmodium parasites transmitted through mosquito bites, infects hundreds of millions globally each year, resulting in nearly 600,000 deaths, primarily among children under five [5]. Group 2: New Drug Development - Novartis announced promising results from Phase 3 clinical trials for GanLum, a new imidazopyridine-based antimalarial drug, which targets the internal protein transport system necessary for the survival of the malaria parasite in human red blood cells [8]. - The clinical trial involved 1,688 malaria patients across 12 African countries, showing GanLum cleared artemisinin-resistant malaria mutations in about 47 hours, compared to 71 hours for artemether-lumefantrine [8]. - GanLum achieved a cure rate of 97.4%, surpassing the 94% cure rate of the standard treatment, with comparable safety profiles [8]. Group 3: Implications and Future Prospects - GanLum is expected to be effective in areas with known artemisinin resistance and can also be used in regions without resistance to slow down the development of drug resistance [10]. - Novartis is currently seeking regulatory approval for GanLum, with expectations for market availability within 12-18 months, marking the first new class of antimalarial drug approved since artemether-lumefantrine [11].
青蒿素概念涨0.40%,主力资金净流入这些股
Group 1 - The core viewpoint of the news is that the Artemisinin concept sector experienced a slight increase of 0.40%, ranking 9th among concept sectors in terms of growth, with two stocks rising and several others declining [1] - Among the stocks in the Artemisinin concept sector, Delong Huineng reached a daily limit increase, while Baihua Pharmaceutical, Fosun Pharmaceutical, and Zhejiang Pharmaceutical saw declines of 1.91%, 1.42%, and 1.30% respectively [1] - The overall market saw a net outflow of 300 million yuan from the Artemisinin concept sector, with only one stock, Rundu Co., receiving a net inflow of 246,700 yuan, marking it as the top stock in terms of net inflow [2] Group 2 - The top-performing concept sectors today included China-Korea Free Trade Zone with an increase of 1.45%, while the worst-performing sector was the military equipment restructuring concept, which fell by 2.91% [2] - The trading volume and turnover rates for stocks in the Artemisinin concept sector varied, with Rundu Co. showing a turnover rate of 1.66% and a slight decline of 0.23%, while other stocks like Baihua Pharmaceutical and Zhejiang Pharmaceutical experienced larger declines and negative net inflows [2]
镜观·回响丨巾帼共绘新时代
Xin Hua She· 2025-10-12 14:01
Core Viewpoint - The articles highlight the significant contributions of women in various fields, emphasizing their roles in advancing society and the economy, particularly in the context of China's modernization and development efforts [1][5]. Group 1: Contributions in Science and Technology - Tu Youyou, a recipient of the "Republic Medal," discovered artemisinin, which significantly reduced malaria mortality rates, saving millions of lives globally [7]. - Shan Xinghua led the development of the 12306 China Railway ticketing system, establishing it as a leading real-time ticketing platform worldwide [8]. - Liang Daihua, a director at Heilongjiang Gushi Biological Group, developed over a hundred nutritional plans that helped farmers increase their income by over 1 billion [10]. Group 2: Participation in Governance and Democracy - The proportion of female representatives in the National People's Congress (NPC) has increased, with 790 women representing 26.5% in 2023, up by 3.1 and 1.6 percentage points from previous sessions [13]. - Female representatives in the NPC proposed 29,328 suggestions, criticisms, and opinions from 2018 to 2025, accounting for 42.3% of the total [14]. - Women accounted for 42.3% of judges and 43.78% of prosecutors in 2024, with female jurors making up 51.5% [15]. Group 3: Cultural Contributions - Fan Jinshi, honorary director of the Dunhuang Research Institute, has made significant contributions to the protection and preservation of the Dunhuang Mogao Caves, establishing regulations and methods for cultural heritage protection [18]. - Women represent 25% of the 3,997 national-level intangible cultural heritage representatives, with 57% of the 51,000 training participants being women [20]. - Young women are becoming key figures in the "national trend" and the living inheritance of intangible cultural heritage, integrating it into contemporary life [21]. Group 4: Sports Achievements - The Chinese women's volleyball team achieved a remarkable victory at the 2023 Hangzhou Asian Games, winning gold for the ninth time, showcasing the spirit of teamwork and resilience [23]. Group 5: Community and Social Services - The "Peaceful Big Sister" team utilizes traditional Chinese mediation methods to resolve disputes and conflicts within communities [24]. - Wang Lanhua, a retired community committee director, has led volunteer services for over 20 years, addressing the needs of the elderly and children in her community [27]. - Women's volunteer fire brigades in Mushan Village conduct fire safety drills and promote fire safety knowledge to protect their community [29]. Group 6: Environmental Protection and Green Development - Yin Yuzhen has transformed over 70,000 acres of desert into arable land, contributing to ecological restoration and sustainable agriculture [31]. - Zhang Jinmei has dedicated decades to cultivating suitable tree species for high-altitude regions, promoting afforestation efforts [32]. - A women's team in Kunming has been actively involved in cleaning up the Dianchi Lake area, contributing to local environmental protection [34].
全释硬科技丨这盛世如您所愿!9组数字致敬中国科学脊梁
Core Viewpoint - The article highlights the contributions of patriotic scientists in China, emphasizing their dedication and sacrifices for the nation's progress and development [1][16]. Group 1: Contributions of Scientists - Qian Weichang, despite his initial struggles in physics, chose to pursue science to serve the country, embodying the spirit of "the needs of the nation are my profession" [4]. - Hua Luogeng, upon hearing about the founding of New China, wrote an open letter urging overseas students to return and contribute to the nation, inspiring many top scientists to come back [6]. - Huang Xuhua dedicated 30 years to developing China's first nuclear submarine, prioritizing national duty over family [6]. - Gu Fangzhou developed a polio vaccine, personally testing it on his own child to ensure its safety, ultimately saving millions of children [6]. Group 2: Research and Innovations - Yuan Longping spent seven years searching for a natural male-sterile rice variety, leading to breakthroughs in hybrid rice research, aiming to eliminate hunger [8]. - Tu Youyou, through extensive research, developed artemisinin, a drug that has saved approximately 6.2 million lives globally [11]. - Deng Jiaxian risked his life during a nuclear test to collect debris, demonstrating his commitment to national security and scientific advancement [13]. - Nan Rendong dedicated 22 years to the construction of the world's largest radio telescope, FAST, showcasing perseverance in scientific endeavors [15]. Group 3: National Pride and Innovation - Ma Weiming led a 20-year effort to develop a key technology for naval power systems, achieving a breakthrough that surpassed American technology [15]. - The article concludes with a reflection on the sacrifices made by these scientists, emphasizing that the nation's stability and progress are due to their relentless efforts and dedication [16].
谭天伟院士:加强生物制造顶层设计,助力我国在未来产业格局竞争中把握主动
Core Viewpoint - The development of biomanufacturing is crucial for enhancing new productive forces in China, with the potential to account for one-third of global manufacturing output by the end of the century, creating a market worth $30 trillion [4]. Group 1: Biomanufacturing Industry Insights - Biomanufacturing is becoming a focal point in national strategic competition, with the U.S. aiming to replace 90% of traditional plastics with bio-based products within 20 years, and the EU implementing a carbon border adjustment mechanism by 2027 [4]. - The technology demonstrates significant potential in addressing resource and environmental challenges, such as using a 50 cubic meter bioreactor to produce artemisinin, which saves 30,000 acres of arable land [4]. - Each ton of bio-based plastic can reduce carbon dioxide emissions by 0.6 tons compared to traditional plastics, contributing to carbon neutrality goals [4]. Group 2: Applications and Innovations - Revolutionary breakthroughs in biomanufacturing are emerging, including the development of biological pheromones for precise pest control, which can replace high-residue pesticides [5]. - The cost of products like hyaluronic acid has significantly decreased due to biomanufacturing, and carbon dioxide is being explored as a third-generation raw material [5]. - The integration of artificial intelligence accelerates innovation, enabling the industrial production of scarce components like catechin from green tea [5]. Group 3: Challenges and Recommendations - Despite holding 70% of global fermentation capacity, the biomanufacturing industry in China faces challenges such as a lack of proprietary strains and limitations in core software tools [5]. - There is a call for enhanced top-level design to focus on cutting-edge areas like carbon dioxide bioconversion and future food manufacturing, aiming to address both green chemical alternatives and protein supply security [5].
致敬历史!那些展品背后的星辰大海
Core Viewpoint - The article emphasizes the importance of university museums and historical exhibits in reflecting the history, culture, and spirit of higher education institutions in China, showcasing their contributions to national development and scientific progress over the past 70 years [1][2]. Group 1: Historical Contributions - Tsinghua University and Peking University have dedicated exhibition areas that honor the contributions of notable figures in China's scientific history, such as the "Two Bombs, One Satellite" pioneers [3][4]. - The "Beijing No. 1" aircraft, designed and built by students and faculty at Beijing University of Aeronautics and Astronautics, represents a significant achievement in China's aviation history, completing its first flight in 1958 after just 100 days of development [5][7]. Group 2: Educational Impact - University museums serve as educational resources, providing students with insights into the historical context of scientific achievements and encouraging them to inherit the spirit of dedication and innovation from their predecessors [9][12]. - The integration of historical exhibits into educational programs, such as the "Aerospace Spirit" lessons at Beijing University of Aeronautics and Astronautics, aims to inspire students to contribute to national defense and technological advancement [12][13]. Group 3: Scientific Achievements - The article highlights various scientific breakthroughs, including the development of the first Chinese laser typesetting system and the discovery of artemisinin by Tu Youyou, showcasing the universities' roles in advancing technology and medicine [9][11]. - The narrative of self-reliance and innovation is prevalent, with universities like Tsinghua and Beihang University leading in research and development across multiple fields, including aerospace and artificial intelligence [11][13].
“诺奖风向标”拉斯克奖出炉,相分离研究先驱获奖,他们阐明了低复杂度结构域的结构和功能
生物世界· 2025-09-12 04:07
Core Points - The Lasker Awards are prestigious biomedical awards in the U.S., established in 1946, recognizing significant contributions in the medical field, often seen as a precursor to the Nobel Prize [2][3] - The 2025 Lasker Award winners include six scientists recognized for their groundbreaking work in basic and clinical medicine [3] Group 1: Lasker Basic Medical Award - Winners: Dirk Görlich and Steven L. McKnight for their discoveries regarding the structure and function of low-complexity domains (LCDs) in proteins, which elucidate new principles of intracellular transport and organization [7][26] - Their research challenges traditional views that LCDs, composed of a limited number of amino acids, are insignificant, revealing that approximately 15%-20% of eukaryotic proteins contain such domains that play crucial roles in various physiological functions [7][26] Group 2: Lasker Clinical Medical Award - Winners: Michael J. Welsh, Jesús González, and Paul A. Negulescu for their pivotal role in developing a three-drug combination therapy for cystic fibrosis, transforming it into a manageable condition [29] Group 3: Lasker Special Achievement Award - Winner: Lucy Shapiro for her 55 years of contributions in bacterial cell biology and national leadership, including the establishment of Stanford University's developmental biology department and her advisory role on issues like antibiotic resistance [30]