智通财经APP获悉，中金发布研报称，维持石药集团(01093)"跑赢行业"评级，考虑对外授权持续兑现上 调目标价9.1%到12港元。该行维持公司25/26年盈利预测47.60亿元/53.53亿元，引入2027年56.95亿元预 期。石药集团公告与阿斯利康签订研发合作与授权协议。 中金主要观点如下： 2025年11月，辉瑞经过与诺和诺德激烈竞价最终以100亿美元对价实现对减肥药研发企业Metsera的收 购，Metsera基于其专有NuSH平台实现了MET-097(GLP-1，临床II期)的超长半衰期，使其具备每月注射 一次的药代动力学基础。而公司SYH2082是一款正推进至临床I期的每月一次注射长效GLP1R/GIP激动 剂，该行期待有更多优异疗效和安全性数据读出。 中国创新药授权出海再获里程碑式突破 对外授权持续兑现，有望形成常态化收入 根据公告，石药集团及附属公司授权阿斯利康在全球范围内(除中国内地/港澳台)独家开发、生产和商业 化8个创新长效多肽药物项目(包括SYH2082及3个临床前阶段分子，并就另4个新增项目进行合作)，阿 斯利康将支付合计12亿美元预付款以及后续累计最高35亿/138亿美元的开发/ ...

内容概要：医药终端指的是药品被消费者购买的市场。医药工业是关系国计民生和国家安全的重要产 业。我国是世界工业医药大国，产业链完整，医药产品品种数量、生产能力位居全球前列。近年来，我 国医药工业高质量发展成效显著，医药终端是药品流通的最终交付环节在中国医药市场的广阔天地中， 长久以来，第一终端（公立医院）与第二终端（零售药店）一直占据着舞台的中心。中国药品终端市场 近年来总体保持稳定增长，但增速有所放缓。2025年前三季度，我国医药三大终端六大市场药品销售总 额达到13924亿元，其中，对公立医院终端药品销售额8290亿元，占终端销售额的59.5%；对零售药店 终端药品销售额4385亿元，占终端销售额的31.5%；对公立基层医疗终端药品销售额1249亿元，占终端 销售额的9.0%。 上市企业：益丰药房[603939]、一心堂[002727]、大参林[603233]、老百姓[603883]、漱玉平民 [301017]、健之佳[605266]、达嘉维康 [301126]、华人健康[301408] 2018-2025年前三季度中国医药三大终端六大市场药品销售总额 在中国医药市场的广阔天地中，长久以来，第一终端（公立医 ...

Macro and Strategy Research - The US economy is expected to maintain resilience due to Trump's tax cuts and tech capital expenditures, with the Fed likely to keep interest rates unchanged amid mixed signals on employment and inflation [2] - The Eurozone is experiencing weak recovery, with uncertainties stemming from geopolitical issues, particularly related to Greenland, which may affect economic stability [2] Domestic Economy - China's GDP growth in Q4 2025 slowed due to high base effects, but overall growth targets were met, with a stronger supply than demand and external demand outpacing internal demand [3] - High-frequency data suggests that exports may remain strong in early 2026, supported by tax policy adjustments and semiconductor industry performance, while domestic consumption faces challenges [3] - Investment is expected to gradually recover, driven by manufacturing and infrastructure investments, although the real estate sector remains cautious [3] Domestic Policy Environment - The People's Bank of China announced a package of structural monetary policies, indicating potential for further rate cuts and reserve requirement ratio reductions [3] - Fiscal policies, including interest subsidies and risk-sharing measures, are aimed at stimulating economic activity and improving corporate financing willingness [4] Fixed Income Research - The bond market has shown a strong oscillation, with the central bank injecting over 9 trillion yuan into the market, and MLF operations reaching 900 billion yuan [6] - The issuance of local government bonds has lengthened in duration, reflecting strategies to take advantage of low interest rates [6] - The bond market is expected to continue its oscillation, with inflation and monetary policy being key factors influencing market dynamics [7] Industry Research - The pharmaceutical industry is witnessing significant collaborations, such as the strategic partnership between CSPC Pharmaceutical and AstraZeneca for innovative long-acting peptide drug development [8] - The SW Pharmaceutical sector index shows a TTM P/E ratio of 51.60, with a valuation premium of 259% over the CSI 300 index [9] - Investment opportunities are identified in innovative drugs, CXO, and upstream life sciences, with a focus on AI applications in healthcare and pharmaceuticals [9]

来源：光大证券微资讯 热点聚焦 HOT 1、沙特股市2月1日大幅下挫，沙特全指跌幅一度达到2.6%，创2025年6月中旬以来最大盘中跌幅。此 前，伊朗军方警告称，德黑兰可能对以色列发动打击。伊朗其他官员也称正在采取措施，为可能的袭击 做准备。2月1日，以军称对黎巴嫩南部发动打击。以美军方高层被曝周末密集会谈，讨论对伊朗打击行 动。另据报道，白宫下令美海军舰艇前往中东，市场对美国可能发动打击的担忧加剧。 2、2月2日7:20，现货白银延续跌势，日内跌幅扩大至10%，报76.89美元/盎司。现货黄金跌破4700美 元，日内跌3.33%。此前，白宫提名前美联储理事凯文·沃什担任下任美联储主席。美东时间上周五，因 担忧沃什的鹰派立场，贵金属获利抛压激增，金、银出现崩盘式跳水，现货白银盘中一度暴跌36%，现 货黄金最高跌超12%。现货铂金重挫17.59%。现货钯金重挫14.89%。 3、1月31日，美股三大指数集体收跌。道指1月累涨1.73%；纳指1月累涨0.95%；标普500指数1月累涨 1.37%。黄金、白银股大幅下挫，全球最大白银ETF--iShares Silver Trust跌28%。纳斯达克中国金龙指数 1 ...

Investment Rating - The report suggests focusing on innovative drugs, brain-computer interfaces, and AI medical applications, indicating a positive outlook for these sectors [1]. Core Insights - The pharmaceutical industry index decreased by 3.31% this week, underperforming the CSI 300 index by 3.39 percentage points. However, since the beginning of 2026, the pharmaceutical sector has increased by 3.14%, outperforming the CSI 300 by 1.49 percentage points [5][12]. - The current valuation level (PE-TTM) for the pharmaceutical industry is 29.40 times, with a premium of 61.10% relative to the entire A-share market [22]. - Notable sub-sectors include blood products, which had the best performance this week with a decline of only 1.0%, while the top three performing sectors since the beginning of the year are hospitals (+12.0%), offline pharmacies (+9.3%), and medical R&D outsourcing (+6.7%) [28]. Summary by Sections Investment Strategy - The report highlights a robust combination of companies including 恒瑞医药 (Hengrui Medicine), 百济神州-U (BeiGene), 美好医疗 (Meihua Medical), and others, indicating their potential for growth and investment [19]. Market Performance - The pharmaceutical industry index's performance this week was ranked 23rd, while its year-to-date performance ranked 22nd among all sectors [5][20]. - The report notes that 60 stocks in the pharmaceutical sector had positive returns this week, while 420 stocks declined [35]. Company News - 先声药业 (Xiansheng Pharmaceutical) has authorized勃林格殷格翰 (Boehringer Ingelheim) for its drug SIM0709, with an upfront payment of €42 million and a total deal value of €1.058 billion [13]. - 石药集团 (Shijiazhuang Pharmaceutical) has partnered with 阿斯利康 (AstraZeneca) for a long-acting peptide project, which includes an upfront payment of $1.2 billion and potential milestone payments totaling $3.5 billion [14]. - 同源康 (Tongyuan Pharmaceutical) has its drug TY9591 included in the priority review list, expected to be launched in 2026, targeting EGFR mutation NSCLC brain metastasis patients [15]. Financial Data - The total market capitalization of the pharmaceutical industry is approximately ¥52,861.60 billion, with a circulating market value of ¥48,153.47 billion [3]. - The industry’s TTM PE ratio stands at 37.3, compared to the CSI 300's PE ratio of 14.2, indicating a significant premium for the pharmaceutical sector [3]. Additional Insights - The report emphasizes the importance of innovative drug development and strategic partnerships in driving growth within the pharmaceutical industry, particularly in the context of emerging therapies and technologies [1][19].

Investment Rating - The report maintains an "Outperform" rating for multiple companies in the healthcare sector, including BeiGene, JD Health, WuXi Biologics, and others, while China National Pharmaceutical Group is rated "Neutral" [1]. Core Insights - The Hong Kong healthcare sector experienced a broad-based correction due to capital pressures, with pharmaceutical distribution remaining relatively stable [4][28]. - The Hang Seng Healthcare Index fell by 3.0% this week, underperforming the Hang Seng Index by 5.4 percentage points, but has gained 8.6% year-to-date, outperforming the Hang Seng Index by 1.7 percentage points [14][27]. - The top five gainers in the sector included Leads Biolabs-B (+19.3%), Sihuan Pharmaceutical (+17.9%), and Tigermed (+7.6%), while the bottom five decliners included Medlive Technology (-16.2%) and Laekna-B (-14.1%) [4][29]. Summary by Sections Market Performance - The report indicates that various sub-sectors within the healthcare market have experienced declines, with pharmaceutical distribution down by 0.3%, internet healthcare down by 2.1%, and medical devices down by 5.0% [4][28]. Company Updates - Rongchang Biopharmaceutical announced a revenue forecast of 3.25 billion yuan for 2025, representing a year-on-year increase of 89%, and has turned a profit [11]. - A collaboration agreement was signed between CSPC Pharmaceutical and AstraZeneca, involving a total payment of $18.5 billion for the licensing of GLP-1 long-acting assets [11]. - AstraZeneca plans to invest $15 billion in China by 2030, focusing on expanding drug manufacturing and R&D capabilities [12]. - Kangzheng Pharmaceutical's lebrikizumab cream has been approved for the treatment of non-segmental vitiligo in patients aged 12 and older [12]. Regulatory Developments - The National Health Commission approved a pilot program for internet-based first consultations in Beijing, which is expected to accelerate prescription outflow [13].

Group 1 - The article highlights the top short-selling ratios for various companies, with JD Health-R, Anta Sports-R, and Lenovo Group-R leading the list at 100.00%, 89.98%, and 89.87% respectively [1][2] - The top three companies by short-selling amount are CSPC Pharmaceutical Group at 1.268 billion, Zijin Mining Group at 1.031 billion, and Xiaomi Group-W at 1.014 billion [1][2] - The highest deviation values in short-selling are recorded for Kuaishou-WR at 36.02%, Xiaomi Group-WR at 30.00%, and Heptagon Pharmaceuticals-B at 26.77% [1][2] Group 2 - The top ten short-selling ratios include JD Health-R at 100.00%, Anta Sports-R at 89.98%, and Lenovo Group-R at 89.87%, with Kuaishou-WR and Xiaomi Group-WR also featuring prominently [2] - The top ten short-selling amounts show CSPC Pharmaceutical Group leading with 1.268 billion, followed by Zijin Mining Group and Xiaomi Group-W [2] - The top ten deviation values indicate significant short-selling activity, particularly for Kuaishou-WR and Xiaomi Group-WR, suggesting potential volatility [2]

Investment Rating - The report maintains an "Outperform" rating for multiple companies in the healthcare sector, including BeiGene, JD Health, WuXi Biologics, and others, while China National Pharmaceutical Group is rated "Neutral" [1]. Core Insights - The Hong Kong healthcare sector experienced a broad-based correction due to capital pressures, with pharmaceutical distribution remaining relatively stable [4][28]. - The Hang Seng Healthcare Index fell by 3.0% this week, underperforming the Hang Seng Index by 5.4 percentage points, but has gained 8.6% year-to-date, outperforming the Hang Seng Index by 1.7 percentage points [14][27]. - The top five gainers in the sector included Leads Biolabs-B (+19.3%), Sihuan Pharmaceutical (+17.9%), and Tigermed (+7.6%), while the bottom five decliners included Medlive Technology (-16.2%) and Laekna-B (-14.1%) [4][29]. Summary by Sections Market Performance - The report indicates that various sub-sectors within the Hong Kong healthcare market experienced declines, with pharmaceutical distribution down by 0.3%, internet healthcare down by 2.1%, and medical devices down by 5.0% [4][28]. Company Highlights - Rongchang Biopharmaceutical announced a revenue forecast of 3.25 billion yuan for 2025, representing an 89% year-on-year increase, and reported a turnaround to profitability [11]. - A collaboration agreement was signed between CSPC Pharmaceutical and AstraZeneca, involving a total payment of $18.5 billion for the licensing of GLP-1 long-acting assets [11]. - AstraZeneca plans to invest $15 billion in China by 2030, focusing on expanding drug manufacturing and R&D capabilities [12]. - Kangzheng Pharmaceutical's lebrikizumab cream has been approved for the treatment of non-segmental vitiligo in patients aged 12 and older [12]. Regulatory Developments - The National Health Commission approved a pilot program for internet-based first consultations in Beijing, which is expected to accelerate prescription outflow and improve access to healthcare services [13].

证 券 研 究 报 告 行业周报 技术加持稳定原料药出口竞争力 医药行业周报 分析师：胡博新 SAC编号：S1050522120002 分析师：吴景欢 SAC编号：S1050523070004 医 药 行 业 观 点 2 诚信、专业、稳健、高效 请阅读最后一页重要免责声明 医 药 行 业 观 点 投资评级： 报告日期： 推荐 （ 维持 ） 2026年02月01日 1.技术加持稳定原料药出口竞争力，重视供给变量 根据医保商会数据，2025年中国医药保健品出口额1113.41亿美元，增长3.14%，其中西药原料出口额428.67亿美元，占西 药总出口的76.8%，同比微降0.27%。原料药出口能保持出口总量的相对稳定，是克服全球贸易变局和内部价格竞争内卷下 实现的，是中国原料药产业竞争力的体现。受关税贸易影响，2025年中国对美国医药出口下降了10.6%，而非美市场，欧 盟增长11.38%，新兴市场增长4.49%。展望2026年原料药贸易依然存在较多的不确定性，中国与印度之间原料药竞争合作 将进一步演绎。价格方面，价格竞争内卷是一方面，另一方面合成生物学等新技术加持，新工艺新产能的投产，单位成本 下降是重要一面。 ...

Investment Rating - The industry investment rating is "Outperform the Market" (预计6个月内，行业指数表现强于市场表现5%以上) [31] Core Insights - On January 30, 2023, the report highlights that the company has signed a strategic R&D cooperation and licensing agreement with AstraZeneca to develop innovative long-acting peptide drugs using its proprietary sustained-release drug delivery technology and peptide drug AI discovery platform [3] - AstraZeneca will gain global exclusive rights to the company's weight management product portfolio, which includes a clinical-ready project SYH2082 and three preclinical projects targeting obesity and weight-related issues [3] - The company is set to receive $1.2 billion in upfront payments, with potential milestone payments of up to $3.5 billion for R&D and up to $13.8 billion in sales milestone payments, along with a double-digit percentage royalty on annual net sales of the licensed products [3] Summary by Sections Industry Overview - The report emphasizes the increasing recognition of Chinese innovative pharmaceutical companies by international multinational corporations (MNCs), particularly through the recent collaboration with AstraZeneca [4] - The report also notes AstraZeneca's plan to invest $15 billion in China by 2030 to expand drug manufacturing and R&D, leveraging China's scientific capabilities and manufacturing strengths [4] Investment Strategy - The report suggests that the global competitiveness of Chinese innovative pharmaceutical companies is continuously improving, with a focus on potential treatment areas such as metabolic diseases, chronic diseases, and central nervous system disorders [5] - It recommends paying attention to emerging fields like small nucleic acid drugs, radioactive drugs, and CAR-T therapies, highlighting specific companies to watch [5] Market Performance - The pharmaceutical sector experienced a decline of 3.31% last week, ranking 20th among 28 industries, while the Hong Kong pharmaceutical sector fell by 2.98% [9][30] - The report indicates that the valuation of the pharmaceutical sector is at 32.45 times (TTM), with a premium of 15.83% compared to the overall A-shares [23]