Core Viewpoint - Kelong Pharmaceutical's stock price has shown fluctuations, with a year-to-date increase of 12.54%, but recent declines over various trading periods indicate potential volatility in investor sentiment [1][2]. Financial Performance - For the period from January to September 2025, Kelong Pharmaceutical reported a revenue of 13.277 billion yuan, representing a year-on-year decrease of 20.92%. The net profit attributable to shareholders was 1.201 billion yuan, down 51.41% year-on-year [2]. - Cumulatively, Kelong Pharmaceutical has distributed 6.898 billion yuan in dividends since its A-share listing, with 3.587 billion yuan distributed over the past three years [3]. Stock Market Activity - As of November 12, Kelong Pharmaceutical's stock was trading at 32.98 yuan per share, with a market capitalization of 52.704 billion yuan. The stock experienced a net inflow of 7.8043 million yuan from main funds [1]. - The company has appeared on the "Dragon and Tiger List" twice this year, with the most recent instance on April 30, where it recorded a net purchase of 31.8792 million yuan [1]. Shareholder Structure - As of September 30, 2025, Kelong Pharmaceutical had 37,100 shareholders, an increase of 8.35% from the previous period. The average number of circulating shares per shareholder was 35,200, a decrease of 7.70% [2]. - The top ten circulating shareholders include various funds, with notable reductions in holdings for several institutional investors [3].

Investment Rating - The report suggests a cautious investment outlook for the pharmaceutical and biotechnology sector, highlighting a slow recovery influenced by various factors such as price reductions from centralized procurement and healthcare cost control measures [2][12]. Core Insights - The overall performance of the pharmaceutical and biotechnology sector is under pressure, with a slight improvement in Q3 2025. The 452 listed companies in this sector reported total revenue of CNY 1.85 trillion, a year-on-year decrease of 1.9%, and a net profit of CNY 140.6 billion, down 4.8% year-on-year [2][12]. - The sector's overall gross margin stands at 30.87%, down 0.66 percentage points year-on-year, while the net margin is at 8.00%, down 0.28 percentage points year-on-year, indicating historically low profitability [2][29]. - There is significant performance differentiation among sub-sectors, with innovative drugs showing strong growth. The top five sub-sectors by revenue growth in Q3 2025 are innovative drugs (+23.34%), CXO (+12.36%), other biological products (+8.15%), upstream reagents (+6.11%), and pharmacies (+0.74%) [2][35]. Summary by Sections 1. Industry Overview - The pharmaceutical manufacturing industry achieved revenue of CNY 1.82 trillion in the first three quarters of 2025, a year-on-year decline of 2.00%, with total profits of CNY 253.48 billion, down 0.70% year-on-year [11][12]. - The industry's revenue and profit growth rates are significantly below the national industrial growth rate of 6.20%, indicating ongoing pressure [11][12]. 2. Sub-sector Performance - The innovative drug sector continues to perform well, with a revenue increase of 23.34% and a net profit growth of 94.98% in Q3 2025 [2][35]. - The CXO sector also shows strong performance, with a revenue increase of 12.36% and a net profit increase of 55.90% [2][93]. - Other sub-sectors such as upstream reagents and pharmacies also reported positive growth, while traditional sectors like raw materials and vaccines faced significant declines [2][35][137]. 3. Company Recommendations - The report recommends focusing on investment opportunities in innovative drug chains, medical devices, healthcare services, second-class vaccines, chain pharmacies, traditional Chinese medicine, and raw materials [2]. 4. Market Trends - As of November 6, 2025, the pharmaceutical and biotechnology sector has seen an 18.61% increase, underperforming compared to the CSI 300 index [36]. - The sector's valuation is at a historical median level, with a PE ratio of 30.13, indicating a potential for recovery as market conditions improve [41].

Core Viewpoint - Tonghua Jinma's stock price has shown significant growth this year, with a year-to-date increase of 76.75%, despite a slight decline in the last five trading days [1][2]. Financial Performance - For the period from January to September 2025, Tonghua Jinma reported operating revenue of 892 million yuan, a year-on-year decrease of 7.88%, while the net profit attributable to shareholders increased by 4.35% to 24.96 million yuan [2]. - The company has cumulatively distributed 210 million yuan in dividends since its A-share listing, with no dividends paid in the last three years [3]. Stock Market Activity - As of November 11, 2023, Tonghua Jinma's stock was trading at 27.75 yuan per share, with a market capitalization of 26.82 billion yuan [1]. - The stock has appeared on the "Dragon and Tiger List" twice this year, with the most recent net purchase of 142 million yuan on September 11 [1]. Shareholder Structure - As of September 30, 2025, the number of shareholders was 38,200, a decrease of 3.20% from the previous period, with an average of 25,266 circulating shares per shareholder, an increase of 3.31% [2][3]. - Notable shareholders include Innovation Drug and Southern CSI 1000 ETF, with changes in their holdings compared to the previous period [3].

Core Viewpoint - Dezheng Health's stock price has experienced fluctuations, with a year-to-date increase of 39.30%, but a recent decline in trading performance [1][2]. Group 1: Stock Performance - On November 11, Dezheng Health's stock fell by 2.02%, trading at 4.36 CNY per share, with a total market capitalization of 9.143 billion CNY [1]. - The stock has seen a net outflow of 21.3992 million CNY in principal funds, with significant selling pressure observed [1]. - Year-to-date, the stock has risen by 39.30%, but has seen a slight decline of 1.13% over the last five trading days [1]. Group 2: Financial Performance - For the period from January to September 2025, Dezheng Health reported a revenue of 278 million CNY, a year-on-year decrease of 21.71%, and a net profit attributable to shareholders of -61.0254 million CNY, a significant decline of 854.37% [2]. - The company has not distributed any dividends in the last three years, with a total payout of 470 million CNY since its A-share listing [3]. Group 3: Shareholder Information - As of September 30, 2025, the number of shareholders decreased to 57,600, with an average of 36,404 circulating shares per person, reflecting a slight decline [2]. - The Hong Kong Central Clearing Limited has exited the list of the top ten circulating shareholders [3].

Core Viewpoint - Yipinhong's stock price has experienced significant fluctuations, with a year-to-date increase of 186.93% but a recent decline in the last five, twenty, and sixty trading days [1][2]. Company Overview - Yipinhong Pharmaceutical Group Co., Ltd. is located in Guangzhou, Guangdong Province, and was established on February 4, 2002, with its listing date on November 16, 2017. The company focuses on the research, production, and sales of its own pharmaceuticals, as well as the sales of agent pharmaceuticals [1]. - The main business revenue composition includes: Children's medicine 61.12%, Chronic disease medicine 22.71%, Others 16.17% [1]. Financial Performance - For the period from January to September 2025, Yipinhong reported operating revenue of 814 million yuan, a year-on-year decrease of 34.35%. The net profit attributable to the parent company was -136 million yuan, a year-on-year increase of 44.80% [2]. - Since its A-share listing, Yipinhong has distributed a total of 335 million yuan in dividends, with 151 million yuan distributed in the last three years [3]. Shareholder Information - As of October 31, the number of Yipinhong's shareholders reached 20,700, an increase of 9.42% from the previous period. The average circulating shares per person decreased by 8.61% to 20,156 shares [2]. - Notable new institutional shareholders include Hong Kong Central Clearing Limited, holding 4.1496 million shares, and Guangfa Healthcare Stock A, holding 3.0452 million shares [3].

Core Viewpoint - Kelong Pharmaceutical's stock has experienced a decline of 2.04% on November 11, with a current price of 32.25 CNY per share and a total market capitalization of 51.537 billion CNY. The company has seen a year-to-date stock price increase of 10.05%, but has faced recent declines over various trading periods [1][2]. Financial Performance - For the period from January to September 2025, Kelong Pharmaceutical reported a revenue of 13.277 billion CNY, representing a year-on-year decrease of 20.92%. The net profit attributable to shareholders was 1.201 billion CNY, down 51.41% compared to the previous year [2]. - Cumulatively, Kelong Pharmaceutical has distributed a total of 6.898 billion CNY in dividends since its A-share listing, with 3.587 billion CNY distributed over the last three years [3]. Shareholder Information - As of September 30, 2025, Kelong Pharmaceutical had 37,100 shareholders, an increase of 8.35% from the previous period. The average number of circulating shares per shareholder decreased by 7.70% to 35,200 shares [2]. - The top ten circulating shareholders include notable funds such as China Europe Medical Health Mixed A and Hong Kong Central Clearing Limited, with several shareholders reducing their holdings compared to the previous period [3]. Stock Market Activity - Kelong Pharmaceutical has appeared on the stock market's "Dragon and Tiger List" twice this year, with the most recent instance on April 30, where it recorded a net purchase of 318.792 million CNY [1]. - The stock has seen a trading volume of 171 million CNY on the day of the report, with a turnover rate of 0.40% [1]. Business Overview - Kelong Pharmaceutical, established on May 29, 2002, and listed on June 3, 2010, is primarily engaged in the development, production, and sales of large-volume infusion products. The revenue composition includes 48.37% from non-infusion products, 41.28% from infusion products, 7.01% from research projects, and 3.33% from other sources [1]. - The company operates within the pharmaceutical and biotechnology sector, specifically in chemical pharmaceuticals and formulations, and is involved in various concepts such as anesthesia, generic drugs, and innovative drugs [2].

11月11日，必贝特盘中下跌2.01%，截至10:29，报30.65元/股，成交7681.76万元，换手率5.33%，总市 值137.94亿元。 资金流向方面，主力资金净流出679.28万元，大单买入1631.22万元，占比21.24%，卖出2310.51万元， 占比30.08%。 必贝特今年以来股价跌1.16%，近5个交易日跌3.22%。 资料显示，广州必贝特医药股份有限公司位于广东省广州市高新技术产业开发区科学城崖鹰石路25号 A-3栋第七层、第八层，成立日期2012年1月19日，上市日期2025年10月28日，公司主营业务涉及创新 药自主研发。 必贝特所属申万行业为：医药生物-化学制药-化学制剂。所属概念板块包括：抗癌治癌、抗癌药物、生 物医药、次新股、创新药等。 截至10月28日，必贝特股东户数4.80万，较上期增加95870.00%；人均流通股968股，较上期增加 0.00%。2025年1月-9月，必贝特实现营业收入0.00元；归母净利润-1.07亿元。 责任编辑：小浪快报 今年以来必贝特已经1次登上龙虎榜，最近一次登上龙虎榜为11月5日，当日龙虎榜净买入4188.29万 元；买入总计1.11亿元 ...

Core Insights - The stock price of Anglikon increased by 2.07% on November 11, reaching 42.33 CNY per share, with a total market capitalization of 8.539 billion CNY [1] - Year-to-date, Anglikon’s stock has risen by 224.17%, with a recent 3.67% increase over the last five trading days [1] - For the first nine months of 2025, Anglikon reported a revenue of 1.055 billion CNY, a year-on-year decrease of 5.92%, while net profit attributable to shareholders increased by 55.59% to 77.6899 million CNY [2] Financial Performance - Anglikon has been listed on the stock market since October 23, 2018, and has a primary business focus on the research, production, and sales of chemical raw materials and formulations [1] - The revenue composition of Anglikon includes 43.46% from formulations, 39.82% from raw materials, 12.44% from specialty intermediates, 3.72% from others, and 0.56% from pharmaceutical excipients [1] - Cumulative cash dividends since the A-share listing amount to 341 million CNY, with 108 million CNY distributed over the past three years [3] Shareholder Structure - As of September 30, 2025, Anglikon had 28,500 shareholders, an increase of 54.58% from the previous period, with an average of 6,493 circulating shares per shareholder, a decrease of 35.31% [2] - Notable institutional shareholders include Guangfa Medical Healthcare Stock A, which increased its holdings by 95,050 shares, and new entrants such as Huatai-PineBridge Innovation Medical Mixed A [3]

Core Viewpoint - Hainan Haiyao's stock price has shown volatility, with a recent decline of 2.99% and a year-to-date increase of 28.60%, indicating mixed investor sentiment and market performance [1][2]. Company Performance - As of October 31, Hainan Haiyao reported a revenue of 640 million yuan for the first nine months of 2025, a year-on-year decrease of 20.51%, while the net profit attributable to shareholders was -24.2 million yuan, reflecting a growth of 17.91% compared to the previous year [2]. - The company has not distributed any dividends in the last three years, with a total payout of 466 million yuan since its A-share listing [3]. Stock Market Activity - The stock has experienced a 0.81% decline over the last five trading days and a 12.82% increase over the past 20 days, with a 2.84% decrease over the last 60 days [2]. - Hainan Haiyao has appeared on the stock market's "龙虎榜" three times this year, with the most recent appearance on June 3 [2]. Shareholder Information - As of September 30, 2025, the number of shareholders decreased by 2.47% to 75,600, while the average number of circulating shares per person increased by 2.53% to 15,420 shares [2]. - The seventh largest circulating shareholder is Hong Kong Central Clearing Limited, holding 6.6464 million shares, a decrease of 1.1481 million shares from the previous period [3]. Business Overview - Hainan Haiyao, established on December 30, 1992, and listed on May 25, 1994, operates in the pharmaceutical sector, focusing on traditional and Western medicine, fine chemicals, chemical raw materials, health products, and related import-export trade [2]. - The company's revenue composition includes 29.93% from other products, 25.07% from gastrointestinal products, 18.60% from medical services, 13.27% from raw materials and intermediates, and 10.19% from cephalosporin series [2]. Industry Context - Hainan Haiyao is categorized under the pharmaceutical and biological industry, specifically in the chemical pharmaceutical and chemical preparation sectors, and is associated with concepts such as Hainan Free Trade Zone, private hospitals, low-priced stocks, small-cap stocks, and state-owned enterprise reforms [2].

Investment Rating - The report does not explicitly state an investment rating for the industry [1] Core Insights - The pharmaceutical and biotechnology sector experienced a decline of 2.4% from November 3 to November 7, 2025, underperforming compared to the Wind All A index (0.63%) and the CSI 300 index (0.82%) [2][7] - The rise in flu activity was noted, with the percentage of flu-like illness (ILI) cases reported at 4.7% in the week of October 27 to November 2, 2025, indicating an increase compared to previous weeks and years [2][10] - The final overall survival (OS) results from the HARMONi-A study of Ivosidenib combined with chemotherapy for EGFR-mutant non-small cell lung cancer showed a significant improvement in OS, with a median OS of 16.8 months versus 14.1 months for the control group [2][10] Weekly Market Review - The pharmaceutical and biotechnology sector's performance was down 2.4%, with notable declines in medical research outsourcing (-4.93%), chemical preparations (-4.42%), and other biological products (-4.33%) [7][8] - The leading gainers included Hezhi China (61.1%), Wanze Shares (30.3%), and Fuxiang Pharmaceutical (23.3%), while Changshan Pharmaceutical (-20%), Yifang Bio-U (-17.8%), and Guangshengtang (-15.3%) were the biggest losers [10] Industry News and Key Company Announcements - On November 7, 2025, the final OS analysis of the HARMONi-A study was presented, showing significant results for Ivosidenib in combination with chemotherapy [10][12] - According to data from the Chinese Center for Disease Control, flu-like illness percentages in southern provinces increased to 4.6%, while northern provinces reported 5.1%, both higher than the previous week [10][12] - BeiGene reported a total revenue of $1.412 billion for Q3 2025, a 41% year-on-year increase, driven by a 51% growth in global sales of its product [12][14] - Metsera announced a merger agreement with Pfizer, with an estimated total transaction value of approximately $9 billion [12][14]