急性痛风药物产业链上游为生产提供基础原料，中游企业负责研发生产出高质量药物，下游通过多种渠 道将药物送达患者手中。各环节相互关联，上游的稳定供应和中游的高效生产是保障下游供应的关键， 而下游市场需求的变化又反作用于中上游产业的发展。 华经产业研究院研究团队使用桌面研究与定量调查、定性分析相结合的方式，全面客观的剖析急性痛风 药物行业发展的总体市场容量、产业链、经营特性、盈利能力和商业模式等。科学使用SCP模型、 SWOT、PEST、回归分析、SPACE矩阵等研究模型与方法综合分析急性痛风药物行业市场环境、产业 政策、竞争格局、技术革新、市场风险、行业壁垒、机遇以及挑战等相关因素。根据急性痛风药物行业 的发展轨迹及实践经验，精心研究编制《2025-2031年中国急性痛风药物行业市场调查研究及发展趋势 预测报告》，为企业、科研、投资机构等单位投资决策、战略规划、产业研究提供重要参考。 内容全面 急性痛风药物是指在痛风急性发作期，用于快速缓解关节红、肿、热、痛等炎症症状的药物，其核心作 用是抑制炎症反应、减轻患者痛苦，而非直接降低血尿酸水平（降尿酸治疗多在缓解期进行）。这类药 物需在急性发作后尽早使用，以快速控制症 ...

华鑫证券研报指出，长春高新控股子公司长春金赛药业有限责任公司与丹麦ALK-AbellóA/S公司达成变 应原特异性免疫治疗（AIT）产品合作。此次合作金赛药业将获得ALK自主开发的3款产品在中国大陆 范围内的独家代理权益，其中皮下注射剂型已在中国大陆上市，舌下片剂型正处于Ⅲ期桥接临床研究阶 段。中国也是全球最大尘螨脱敏治疗市场，2023年市场总量超过11亿人民币，3年复合增速12%。金赛 药业与ALK合作期限至2039年，经过长期培育，脱敏领域有望成为金赛药业重要的新增长点。另外， 公司伏欣奇拜单抗为国内首款抗白介素1β（IL-1β）全人源单抗，2025年6月正式获批上市，填补了我国 痛风抗炎领域长效精准靶向治疗的空白。研发投入的增加，子公司金赛药业得以吸引新进人才，并构建 起以ADC为核心的肿瘤新药开发平台。给予"买入"投资评级。 ...

Investment Rating - The report maintains a "Buy" investment rating for the company [1][9]. Core Insights - The collaboration with ALK-Abelló A/S aims to expand the desensitization treatment market, potentially creating new growth points for the company [5]. - The launch of Fuxin Qibai monoclonal antibody addresses the acute treatment of gout, filling a gap in the long-acting targeted therapy market in China [6]. - The company is increasing its R&D investment, particularly in the oncology sector, with a focus on developing new drugs based on ADC technology [7][8]. - Revenue forecasts for 2025-2027 are projected at 133.25 billion, 136.94 billion, and 137.85 billion yuan respectively, with corresponding EPS of 5.66, 5.88, and 6.00 yuan [9][11]. Summary by Sections Market Performance - The current stock price is 120.5 yuan, with a total market capitalization of 49.2 billion yuan and a total share count of 408 million [1]. Investment Highlights - The partnership with ALK allows the company to exclusively distribute three products in mainland China, enhancing its market share in the desensitization treatment sector [5]. - The pediatric market for allergy treatments is significant, with a prevalence rate of 18.46% among children aged 0-18 in China, indicating a strong potential for growth [5]. - Fuxin Qibai has shown promising clinical results, with a 90% reduction in gout recurrence risk at 12 weeks, suggesting a sales potential exceeding 20 billion yuan [6]. R&D Investment - In the first half of 2025, the company invested 1.335 billion yuan in R&D, a 17.32% increase year-on-year, representing 20.21% of its revenue [7]. - The increase in R&D spending is aimed at attracting new talent and establishing a new drug development platform focused on oncology [8]. Financial Projections - The company anticipates a decline in revenue growth rates, with a forecasted decrease of 7.6% in 2024, followed by a slight recovery in subsequent years [11]. - The projected net profit for 2025 is 2.308 billion yuan, reflecting a 10.6% decrease from the previous year [11].

Core Viewpoint - Changchun High-tech is facing significant challenges due to price reductions from centralized procurement of its core products and a lack of new business development, leading to a dramatic decline in net profit by 42.85% in the first half of 2025, marking a potential fall from grace for this once-prominent stock [1][2]. Financial Performance - In the mid-year report of 2025, the company reported revenue of 6.603 billion yuan, a year-on-year decrease of 0.54%, and a net profit attributable to shareholders of 983 million yuan, down 42.85% year-on-year, indicating a continuous decline in both revenue and profit for the first time in 20 years [2][3]. - The second quarter of 2025 showed revenue of 3.605 billion yuan, a slight increase of 4.16% year-on-year, but net profit fell by 48.83% to 463 million yuan, primarily due to rising sales and R&D expenses [2][3]. - Over the past five years, revenue growth has significantly slowed, with figures of 4.963 billion yuan, 5.831 billion yuan, 6.168 billion yuan, 6.639 billion yuan, and 6.603 billion yuan from 2021 to 2025, while net profit has dropped from 1.923 billion yuan in 2021 to 983 million yuan in 2025 [2][3]. Business Structure and Risks - The decline in net profit is largely attributed to the poor performance of its core subsidiary, Jinsai Pharmaceutical, and losses at Baike Biotechnology, highlighting potential risks in the company's business structure and pipeline layout [3][4]. - The company is overly reliant on a few products, making it vulnerable to market changes, increased competition, or quality issues [3][4]. - The shift in the industry from "generic-driven" to "innovation-driven" poses additional challenges for Changchun High-tech, as it faces high R&D costs and long commercialization cycles [4]. Expense Management - The company's mid-year report for 2025 revealed sales expenses of 2.386 billion yuan, up 23.43% year-on-year, and R&D expenses of 1.155 billion yuan, up 30.22%, together accounting for 53.6% of total revenue, significantly squeezing profit margins [5][6]. - The increase in sales expenses is attributed to the promotion of new products and expansion into new medical departments, while the rise in R&D expenses is due to advancements in technology platforms and clinical trials [6][7]. - The high ratio of total expenses to revenue (46.97%) is above the industry average of 35%, indicating structural inefficiencies within the company [7][8]. Future Outlook - The company faces significant challenges in its transformation journey, and how it navigates these business difficulties will be closely monitored [8].

Core Viewpoint - Changchun High-tech is facing significant challenges due to price reductions from centralized procurement of its core product, growth hormone, and a lack of new business opportunities, leading to a dramatic decline in net profit by 42.85% in the mid-2025 report [2][3]. Financial Performance - In the mid-2025 report, the company reported revenue of 6.603 billion yuan, a year-on-year decrease of 0.54%, and net profit attributable to shareholders of 983 million yuan, down 42.85% [3]. - This marks the first occurrence of simultaneous revenue and net profit decline in nearly 20 years for the company [3]. - The second quarter of 2025 showed revenue of 3.605 billion yuan, a slight increase of 4.16% year-on-year, but net profit fell by 48.83% to 463 million yuan, indicating a "revenue without profit" situation due to rising sales and R&D expenses [3]. Business Structure and Risks - The core reason for the "revenue without profit" phenomenon is the decline in net profit from the core subsidiary, Jinsai Pharmaceutical, and losses at Baike Biotechnology [4]. - The company is overly reliant on a single product, which exposes it to risks from market demand changes and increased competition [4]. - The losses at Baike Biotechnology may stem from an unreasonable pipeline layout and poor market prospects for R&D products [4]. Policy and Industry Context - The significant drop in net profit can be attributed to policy impacts and industry cycles, including the expansion of centralized procurement for growth hormone, which saw price reductions exceeding 50% in some regions [5]. - The company’s core product accounts for over 70% of revenue, highlighting its vulnerability due to reliance on a single product [5]. - The domestic innovative pharmaceutical industry is facing challenges transitioning from a "generic-driven" to an "innovation-driven" model, with high R&D costs and long commercialization cycles putting pressure on cash flow [5]. Expense Management - The company reported a significant increase in expenses, with sales expenses reaching 2.386 billion yuan (up 23.43%) and R&D expenses at 1.155 billion yuan (up 30.22%), together accounting for 53.6% of revenue [7]. - The high sales expenses are attributed to market promotion for new products and expansion into new medical departments [7]. - R&D expenses have surged due to the advancement of new technology platforms and clinical trials, with R&D investment reaching 20.21% of revenue, the highest in five years [7]. Comparative Analysis - The company's expense ratio of 46.97% is significantly higher than the industry average of 35%, indicating structural issues in expense management [8]. - The high sales expenses are driven by increased market competition and the need for extensive promotional activities [8]. - In contrast, other companies like Heng Rui Pharmaceutical have managed to reduce their expense ratios through sales team integration and digital marketing strategies, highlighting potential areas for efficiency improvement for Changchun High-tech [9].

本报（chinatimes.net.cn）记者张斯文 于娜 北京报道 曾经凭借生长激素独占市场多年的长春高新，如今正面临核心产品集采降价、新业务青黄不接的艰难局 面，2025年中报显示净利润暴跌42.85%，这家老牌白马股或已跌落神坛。 2021年5月是公司股价巅峰时期，长春高新市值曾超过2100亿元，被投资者誉为"东北药茅"。而如今， 其市值仅500亿元，已缩水超过1600亿元。 中期业绩延续颓势 2025年8月30日，公司交出的中报业绩显示：营业收入66.03亿元，同比下滑0.54%；归属于上市公司股 东净利润9.83亿元，同比下降42.85%。延续了去年年报中出现的营收和净利润双双下滑的局面，这也是 公司近20年来首次出现这一情况。 净利润创近五年中报最大降幅的同时，单季度数据进一步反映出公司"增收不增利"特征：公司2025年 Q2营收36.05亿元，同比微增4.16%，但净利润4.63亿元，同比仍下滑48.83%，这一现象主要源于销售费 用与研发投入的双高增长，对利润形成严重侵蚀。 回顾近5年公司中报数据，2021—2025年1—6月，长春高新营收分别为49.63亿元、58.31亿元、61.68亿 元 ...

Investment Rating - The report assigns an "Accumulate" rating for the company for the first time [2]. Core Views - The company is transitioning from a single large product-driven growth model to a multi-innovative drug-driven growth model, with several innovative drugs entering late-stage clinical trials and market launch [8][17]. - The company maintains a solid leading position in growth hormone products, with multiple innovative drugs opening up new growth opportunities [8][17]. - The newly launched products, such as the nano-crystal form of medroxyprogesterone and the IL-1β inhibitor, are expected to address significant market needs and have the potential to become major products [8][54]. Summary by Sections Company Overview - The company is a comprehensive development enterprise focused on gene-engineered biopharmaceuticals, with its main asset being Changchun Jinsai Pharmaceutical [13]. - The company has a broad business scope, including gene engineering drugs, biological vaccines, and modern traditional Chinese medicine [13]. Financial Performance - The company's revenue slightly declined, with a projected revenue of 13.466 billion yuan in 2024, a year-on-year decrease of 7.55% [8][16]. - The company’s net profit attributable to shareholders is expected to drop significantly in 2024, with a forecast of 2.583 billion yuan, a decrease of 43.01% year-on-year [7][16]. Product Pipeline and Innovation - The company is increasing its R&D investment, with R&D expenses rising from 349 million yuan in 2017 to 2.69 billion yuan in 2024, representing 19.97% of revenue [21][24]. - The company has multiple innovative products in the pipeline, including the recently approved IL-1β inhibitor, which marks a shift from a focus on growth hormones to a broader innovative drug strategy [23][54]. Market Opportunities - The newly launched nano-crystal form of medroxyprogesterone significantly improves patient compliance and accessibility, addressing the challenges of traditional formulations [31][53]. - The approval of the IL-1β inhibitor for acute gout attacks is expected to provide a new treatment option, enhancing the company's product offerings in the pain management market [54]. Revenue Forecast - The company is projected to achieve revenues of 134.08 billion yuan in 2025, 142.99 billion yuan in 2026, and 155.19 billion yuan in 2027, with corresponding net profits of 22.24 billion yuan, 23.01 billion yuan, and 24.58 billion yuan [8][7].

Investment Rating - The report maintains an "Accumulate" rating for Changchun High-tech [6] Core Views - The company is undergoing a critical transformation period, with short-term performance under pressure due to a decline in net profit [1][3] - The subsidiary, Jinsai Pharmaceutical, has stabilized its revenue but faces short-term profit challenges [1][2] - The company is focusing on differentiated innovation with multiple products expected to commercialize in the future [2] Summary by Sections Financial Performance - In the first half of 2025, the company achieved revenue of 6.603 billion yuan, a decrease of 0.54%, and a net profit attributable to shareholders of 983 million yuan, down 42.85% [1][6] - Jinsai Pharmaceutical reported revenue of 5.469 billion yuan, an increase of 6.17%, but a net profit decline of 37.35% [1][2] Research and Development - R&D investment reached 1.335 billion yuan, up 17.32%, accounting for 20.21% of revenue [2] - The approval of new products like Fuxin Qibai monoclonal antibody marks significant progress in the company's R&D pipeline [2] Profit Forecast and Valuation - The forecast for net profit attributable to shareholders for 2025-2027 is 2.102 billion yuan, 2.241 billion yuan, and 2.407 billion yuan, reflecting a year-on-year decline of 18.6% in 2025, followed by growth in subsequent years [3][4] - The company is expected to gradually increase its performance as new products are launched [3]

Investment Rating - The report maintains a "Buy" rating for the company, with expected earnings per share (EPS) of 5.46, 6.06, and 6.78 yuan for the years 2025, 2026, and 2027 respectively, corresponding to price-to-earnings (P/E) ratios of 21, 19, and 17 times [4]. Core Insights - The company reported a slight decrease in revenue of 0.54% year-on-year for the first half of 2025, totaling 6.603 billion yuan, while net profit attributable to shareholders fell by 42.85% to 983 million yuan [2]. - The core subsidiary, Jinsai Pharmaceutical, achieved revenue growth of 6.17% year-on-year, amounting to 5.469 billion yuan, but net profit decreased by 37.35% to 1.108 billion yuan [2]. - The company has significantly increased its R&D investment, reaching 1.335 billion yuan, a 17.32% increase year-on-year, which now constitutes 20.21% of its revenue [2]. Revenue and Profit Analysis - For the second quarter of 2025, the company reported revenue of 3.605 billion yuan, a year-on-year increase of 4.16%, while net profit attributable to shareholders decreased by 40.75% to 510 million yuan [2]. - The report forecasts a decline in net profit for 2025 to 2.225 billion yuan, a 13.85% decrease from the previous year, with a gradual recovery expected in subsequent years [4]. R&D and Product Development - Jinsai Pharmaceutical is focusing on innovative treatments in various therapeutic areas, including immunology and oncology, with new products like the IL-1β monoclonal antibody and GenSci120 injection entering clinical trials [3]. - The company is actively enhancing its R&D capabilities and talent acquisition to support the development of new products, which is reflected in the increased R&D expenses [2][3]. Financial Projections - The company is expected to achieve net profits of 2.225 billion yuan in 2025, 2.471 billion yuan in 2026, and 2.766 billion yuan in 2027, with corresponding EPS of 5.455, 6.056, and 6.779 yuan [4]. - The projected revenue for 2025 is 12.364 billion yuan, reflecting a decline of 8.18% from the previous year, with a gradual recovery anticipated in the following years [9].

Core Viewpoint - Changchun High-tech's stock surged to a six-month high despite disappointing half-year results, driven by optimistic management forecasts regarding innovative drug revenues and potential business development opportunities [1][2]. Group 1: Financial Performance - Changchun High-tech reported a revenue of 6.603 billion yuan, a slight decrease of 0.54% year-on-year, and a net profit of 983 million yuan, down 42.85% year-on-year [1]. - Its subsidiary, Jinsai Pharmaceutical, achieved a revenue of 5.469 billion yuan, an increase of 6.17% year-on-year, but net profit dropped significantly by 37.35% [2]. Group 2: Product Development and Market Position - The company anticipates that revenues from innovative drugs and overseas licensing will exceed 1 billion yuan this year and 1.5 billion yuan next year, with other revenues surpassing traditional growth hormone business by 2027 [1]. - The recently approved drug, Fuxin Qibai monoclonal antibody, is expected to generate peak sales of 5 billion yuan, with a current market price of 8,988 yuan per unit [1][6]. - Jinsai Pharmaceutical is facing increased competition in the long-acting growth hormone market, particularly from Teva Pharmaceutical's newly launched product priced at 1,798 yuan per unit [4][5]. Group 3: Future Outlook and Strategic Plans - The company plans to initiate a Hong Kong IPO in 2026 and aims to add 10-15 new INDs annually from 2025 to 2030, targeting overseas licensing revenues of 5-8 billion yuan by 2030 [1][9]. - Jinsai Pharmaceutical is also preparing for the market entry of three new products, including the promising Fuxin Qibai monoclonal antibody, which is expected to generate 1 billion yuan in sales this year and 6-10 billion yuan next year [6][7].