Core Viewpoint - Yiling Pharmaceutical's subsidiary, Beijing Yiling, has successfully negotiated for its exclusive product, Qifang Nasal Tablets, to be included in the National Medical Insurance Directory (2025 edition) for the first time [1] Group 1: Company Developments - Yiling Pharmaceutical has a total of 12 exclusive products included in the National Medical Insurance Directory (2025 edition), which includes Qifang Nasal Tablets and other products such as Tongxinluo Tablets (Capsules), Ginseng and Pine Nut Heart Nourishing Capsules, and Lianhua Qingwen Tablets (Capsules, Granules) [1] - The inclusion of these products in the medical insurance directory is expected to enhance their market accessibility and potentially increase sales [1] Group 2: Industry Impact - The addition of Yiling Pharmaceutical's products to the National Medical Insurance Directory reflects a broader trend in the industry towards integrating traditional Chinese medicine into the national healthcare system [1] - This move may encourage other companies in the industry to seek similar negotiations for their products, potentially leading to increased competition and innovation within the sector [1]

Group 1 - The core viewpoint of the news highlights the active performance of the traditional Chinese medicine (TCM) sector, particularly in the context of the flu season, with the TCM ETF (560080) rising nearly 1% and experiencing a significant increase in trading volume [1][3] - Recent data from the CDC indicates that the positive rate of flu virus tests in emergency departments nationwide has approached 45%, with some regions experiencing high levels of flu activity, leading to a surge in sales of cold-related medications [3][10] - The TCM ETF (560080) has seen a net inflow of over 24 million yuan as of November 28, with its latest scale reaching 2.581 billion yuan, leading its peers in the same category [1][3] Group 2 - The performance of individual stocks within the TCM ETF has been notable, with several flu-related stocks experiencing significant gains, such as Guangdong Wannianqing hitting the daily limit and Tai Long Pharmaceutical rising over 6% [3][4] - The TCM ETF's index has a TTM price-to-earnings ratio of 24.86, indicating it is cheaper than 79% of the time over the past decade, suggesting a favorable valuation for potential investment [5] - The TCM index has shown negative returns year-to-date, with a decline of 2.24% in 2023, and a historical trend of alternating between gains and losses over the past several years [7][8] Group 3 - The TCM industry is expected to see a short-term easing of pressure due to inventory clearance, with a positive outlook for demand recovery towards the end of the year [10] - Recent price governance initiatives across various regions aim to create a more unified and competitive market for TCM products, focusing on high-priced traditional Chinese medicines [10][11] - The ongoing price governance and centralized procurement processes are likely to reshape competition in the industry, favoring companies with strong clinical value, cost control, and market coverage capabilities [11]

Core Viewpoint - Yiling Pharmaceutical's innovative traditional Chinese medicine, Yangzheng Xiaojie Capsule, has been approved for sale in Thailand, marking a significant milestone in the company's internationalization strategy and highlighting the growing global recognition of traditional Chinese medicine in the oncology field [1][3]. Group 1: Product Approval and Significance - Yangzheng Xiaojie Capsule is the latest product from Yiling Pharmaceutical to receive registration in Thailand, following the success of Lianhua Qingwen Capsule, Shensong Yangxin Capsule, and Jinlidag Granules [1]. - The approval signifies the unique value of traditional Chinese medicine in cancer treatment is increasingly acknowledged internationally [1]. Group 2: Research and Efficacy - Joint research by Professor Jiang Wenguo from Cardiff University and Yiling Pharmaceutical found that Yangzheng Xiaojie Capsule significantly interferes with tumor cell invasion and metastasis by inhibiting the overactivation of the PI3K/Akt signaling pathway [2]. - Clinical studies led by Academician Yu Jinming showed that Yangzheng Xiaojie Capsule combined with chemotherapy significantly improved the quality of life for patients with advanced non-small cell lung cancer, with a clinical symptom improvement rate of 83.5% [2]. - Another study indicated that the combination of Yangzheng Xiaojie Capsule with interventional chemotherapy for primary liver cancer resulted in a total effective rate of 65.2%, significantly higher than the control group's 36.1% [2]. Group 3: Safety Profile - A meta-analysis involving 19 studies and 2,125 patients demonstrated that Yangzheng Xiaojie Capsule effectively alleviates gastrointestinal reactions caused by radiotherapy and chemotherapy, mitigates bone marrow suppression, and protects liver function, indicating good safety [3]. Group 4: Market Expansion - The approval of Yangzheng Xiaojie Capsule in Thailand is a vital step in Yiling Pharmaceutical's international strategy and serves as a practical example of traditional Chinese medicine contributing to the "Belt and Road" initiative [3]. - Yiling Pharmaceutical has successfully registered and launched 17 innovative traditional Chinese medicines in over 50 countries and regions worldwide [3].

Core Insights - Yangzheng Xiaojie Capsule is an innovative traditional Chinese medicine developed under the guidance of traditional Chinese medicine theory, targeting the pathological mechanisms of tumors and has been approved for use in primary liver cancer treatment in China [1][2] Group 1: Product Efficacy - Yangzheng Xiaojie Capsule integrates traditional methods with modern anti-cancer drugs, demonstrating a dual action of supporting the body while eliminating pathogens, which aligns with modern cancer treatment goals [1] - Clinical studies indicate that Yangzheng Xiaojie Capsule significantly improves the quality of life for patients with advanced non-small cell lung cancer, with a clinical symptom improvement rate of 83.5% [2] - In a study on primary liver cancer, the combination of Yangzheng Xiaojie Capsule with interventional chemotherapy resulted in a total effective rate of 65.2%, significantly higher than the control group's 36.1% [2] Group 2: Research and Validation - Research led by Professor Jiang Wenguo from Cardiff University found that Yangzheng Xiaojie Capsule can significantly interfere with tumor cell invasion and metastasis by inhibiting the excessive activation of the PI3K/AKT signaling pathway [1] - The same research also indicated that the capsule inhibits the activity of focal adhesion kinase, thereby suppressing tumor angiogenesis, which contributes to tumor starvation [1] Group 3: Market Expansion - Yangzheng Xiaojie Capsule has recently been approved in Thailand, marking a significant milestone in Yiling Pharmaceutical's internationalization strategy and demonstrating the practical application of traditional Chinese medicine in the "Belt and Road" initiative [4] - Yiling Pharmaceutical has successfully registered 17 innovative traditional Chinese medicines in over 50 countries and regions worldwide, indicating strong international market recognition [4]