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恒润达生IPO迷局:未盈利却估值百亿元,是创新先锋还是资本泡沫|创新药观察
Hua Xia Shi Bao· 2025-07-10 08:37
Core Viewpoint - Hengrun Dazheng, a biotech company focused on immune cell therapy, is attempting to go public on the Sci-Tech Innovation Board despite being unprofitable and facing significant financial losses. The company has not yet commercialized any products and is at risk of delisting if it fails to meet financial performance criteria post-IPO [1][2][5]. Financial Performance - Hengrun Dazheng has reported substantial losses over the past three years, with net losses of CNY 274 million, CNY 283 million, and CNY 188 million from 2022 to 2024. As of the end of 2024, the cumulative undistributed profits stand at -CNY 904 million [2][3]. - The company has incurred high R&D expenses, amounting to CNY 242 million, CNY 256 million, and CNY 152 million from 2022 to 2024, contributing to its financial losses [3]. - Cash flow from operating activities has been negative, with net cash flows of -CNY 209 million, -CNY 226 million, and -CNY 141 million during the same period, leading to a significant reduction in liquid assets [3]. Liquidity and Solvency - Hengrun Dazheng's liquidity ratios, including current and quick ratios, have been declining, indicating insufficient debt repayment capacity. The debt-to-asset ratio has increased significantly, reaching 84.76% by the end of 2024, which is considerably higher than the average of comparable companies [3][4]. Product Development and Market Position - The company is developing a pipeline of 11 projects, including CAR-T and CAR-NK therapies, with the most advanced products HR001 and HR003 expected to enter the market by 2025. However, these products face competition from at least six already approved CAR-T therapies in China [7][8]. - The efficacy and safety of Hengrun Dazheng's core products have been questioned, with HR001 showing an overall response rate (ORR) of 68%, which is lower than competitors, and HR003 showing an ORR of 86%, also below market standards [9][10]. IPO and Valuation - Hengrun Dazheng plans to issue up to 50 million shares, aiming to raise CNY 2.539 billion for R&D and operational expenses. The estimated post-IPO valuation exceeds CNY 10 billion, which is considered high given the competitive landscape and the company's current lack of revenue [11].
华东医药(000963):25Q1扣非净利YOY+17%,符合预期
2025 年 05 月 09 日 王睿哲 C0062@capital.com.tw 目标价(元) 47.8 公司基本信息 | 产业别 | | | | 医药生物 | | --- | --- | --- | --- | --- | | A 股价(2025/5/8) | | | | 39.03 | | 深证成指(2025/5/8) | | | | 10197.66 | | 股价 12 个月高/低 | | | | 40.8/25.63 | | 总发行股数(百万) | | | | 1754.08 | | A 股数(百万) | | | | 1751.94 | | A 市值(亿元) | | | | 683.78 | | 主要股东 | | | | 中国远大集团有 | | | | | | 限责任公司 | | | | | | (41.67%) | | 每股净值(元) | | | | 13.72 | | 股价/账面净值 | | | | 2.85 | | | 一个月 | | 三个月 一年 | | | 股价涨跌(%) | | 5.8 | 13.5 18.8 | | | 近期评等 | | | | | | 日期 | 收盘价 | | 评级 ...
群益证券:给予华东医药增持评级,目标价47.8元
Zheng Quan Zhi Xing· 2025-05-09 07:09
Company Performance - In Q1 2025, the company reported revenue of 10.74 billion yuan, a year-over-year increase of 3.1%, and a net profit attributable to shareholders of 920 million yuan, up 6.1% year-over-year [1] - The company's non-recurring net profit was 900 million yuan, reflecting a year-over-year growth of 7.0%, while the actual year-over-year growth of non-recurring net profit was 17.2%, indicating double-digit growth [1] - The core subsidiary, China Medical East, achieved revenue of 3.62 billion yuan in Q1 2025, a year-over-year increase of 6.5%, with a consolidated net profit of 843 million yuan, up 12.2% year-over-year [2] Product Performance - The sales of innovative drugs are gaining momentum, with the CAR-T product, Saikeze, seeing a steady increase in effective orders, now covered by over 70 insurance providers [2] - The company’s overseas medical beauty segment faced challenges, with revenue from UK-based Sinclair down 12.3% year-over-year, while domestic medical beauty subsidiary achieved revenue of 250 million yuan, a slight decline of 1.4% [2] - The company’s medical commercial segment performed steadily, with Q1 2025 revenue of 6.93 billion yuan, a year-over-year increase of 3.2%, and a net profit of 120 million yuan, up 7.3% year-over-year [2] Financial Metrics - The overall gross margin for Q1 2025 was 32.9%, an increase of 0.9 percentage points year-over-year, driven by changes in sales structure [3] - The company’s expense ratio was 22.0%, an increase of 0.8 percentage points year-over-year, primarily due to a 2.1 percentage point increase in R&D expense ratio [3] Future Outlook - The company is expected to see continued growth, with diminishing marginal impacts from centralized procurement and the launch of new innovative drugs and medical beauty products [3] - Projected net profits for 2025, 2026, and 2027 are 4.07 billion yuan, 4.78 billion yuan, and 5.57 billion yuan, representing year-over-year growth rates of 15.9%, 17.6%, and 16.5% respectively [3] - The company has received a "buy" investment rating with a target price of 47.8 yuan [1][3]