Core Viewpoint - The study presented at the 2025 ASCO annual meeting indicates that the combination of Adebali monoclonal antibody, Bevacizumab, and Cisplatin/Carboplatin may provide a new treatment option for patients with advanced triple-negative breast cancer (TNBC) with brain metastases [1][2]. Group 1: Study Overview - The study is a single-center, single-arm Phase II clinical trial involving 35 patients with recurrent metastatic TNBC and brain metastases who had not previously received Bevacizumab or PD-1/PD-L1 inhibitors [2]. - Patients received Adebali monoclonal antibody (20 mg/kg) combined with Bevacizumab (7.5 mg/kg) and either Cisplatin (75 mg/m²) or Carboplatin (AUC=5) until disease progression or intolerable side effects occurred [2]. Group 2: Efficacy and Safety Results - The primary endpoint was the central nervous system objective response rate (CNS-ORR) assessed by RANO-BM criteria, with secondary endpoints including CNS clinical benefit rate (CNS-CBR), progression-free survival (PFS), overall survival (OS), and safety [2]. - As of April 10, 2025, the confirmed CNS-ORR was 77.1% (27 out of 35 patients), and the CNS-CBR was 80% (28 out of 35 patients) [2]. - The median CNS-PFS was 11.5 months (range 6.2-NR), and the overall median PFS was 8.3 months (range 5.8-11.5) [2]. Group 3: Subgroup Analysis - Subgroup analysis revealed that in the PD-L1 negative population (CPS<1), the CNS-PFS was 11.5 months, while in the PD-L1 positive population (CPS≥1), the CNS-PFS had not yet been reached due to insufficient events [3]. - The study introduced the "Fudan classification" for TNBC, showing that in the immune regulatory type (IM type), the CNS-PFS had not been reached, while in the non-immune regulatory type (Non-IM type), the CNS-PFS was 10 months [3]. - Overall PFS demonstrated significant differences between the IM type (19 months) and Non-IM type (6.1 months) [3]. Group 4: Conclusion and Future Directions - The combination treatment of Adebali monoclonal antibody, Bevacizumab, and Cisplatin/Carboplatin is the first to show high intracranial anti-tumor activity and prolonged CNS-PFS and PFS in TNBC with brain metastases, with good safety profile [3]. - The study suggests that PD-L1 status and TNBC "Fudan classification" may predict the efficacy of this combination therapy, warranting further research to validate these findings [3].

Core Viewpoint - The collaboration between Wuxi College's "Membrane Intelligent Connection" team and Jiangyin Tianhua and Wuxi Wujing aims to enhance the development of a new modified polyimide project through deep integration of industry, academia, and research [1][2] Group 1: Collaboration Details - The partnership is facilitated by the Wuxi Sensor Network National University Science Park, which focuses on transforming university technology achievements into productivity [1] - The three parties will leverage their strengths: the "Membrane Intelligent Connection" team will provide core technical support, Jiangyin Tianhua will optimize production processes, and Wuxi Wujing will assist in market promotion and application expansion [1] Group 2: Research and Development Focus - The collaboration will involve joint investment in R&D resources to address technical challenges related to the application of modified polyimide in 5G communication and electronic information fields [1] - There will be an emphasis on talent cultivation and exchange, establishing a joint talent training mechanism to nurture high-quality professionals for project development [1] Group 3: Industry Impact - Experts indicate that this collaboration represents a typical case of deep integration of industry, academia, and research, which is expected to accelerate the industrialization of the new modified polyimide project [2] - The partnership is anticipated to enhance China's independent innovation capability and market competitiveness in the high-performance materials sector, providing strong support for the development of related industries [2]

Core Insights - The Taicang Alps International Resort Phase II project, with a total investment of approximately 5 billion yuan, has commenced construction and is scheduled to open in June 2029 [1] - The project aims to create the world's largest and highest-quality one-stop ice and snow themed resort, enhancing cultural tourism consumption in the Yangtze River Delta region through a new model of government-enterprise cooperation [1] - The first phase of the project has successfully attracted over 1 million visitors, establishing itself as a benchmark tourism project in the Yangtze River Delta [1] Project Details - The Phase II project will cover a total construction area of approximately 300,000 square meters and will feature a world-class indoor ski resort, two international themed hotels, and six major entertainment projects including a polar ocean park and a hot spring water park [1] - The project aims to provide comprehensive, international one-stop vacation services that integrate ice and snow sports, themed entertainment, leisure shopping, and quality accommodation [1] Unique Features - The indoor ski resort in Phase II will create five "world firsts," including the longest indoor ski slope at 650 meters, the largest vertical drop of 100 meters, and the largest cold area exceeding 100,000 square meters [2] - The project will also be the world's first AI ski resort, utilizing artificial intelligence for dynamic monitoring and regulation of the ski area [2] - The chairman of Fosun International, Guo Guangchang, emphasized the strategic advantages of Taicang's location and business environment, aiming to position the project as a new benchmark for ice and snow tourism in China [2]

Group 1 - The core idea of the news is the collaboration between Jiangsu Rural Commercial Bank and Zijin Rural Commercial Bank to promote financial technology and enhance public awareness of technological innovation through a community event in Nanjing [1][2] - The event consists of three main sections: "Technology Promotion," "Elderly Assistance," and "Convenience Market," aimed at integrating financial technology services with public needs [1][2] - The technology promotion area showcased China's historical achievements in technological innovation and distributed the newly revised "Law on the Popularization of Science and Technology," aiming to inspire youth and cultivate future innovators [1][2] Group 2 - In the "Elderly Assistance" section, the "Little Circle Service Team" provided one-on-one training for elderly individuals on using smart devices, resulting in successful online payment experiences for participants [2] - The event included a "Fraud Prevention" segment where residents were educated on recognizing various scams, with over 120 anti-fraud manuals distributed and 95% of participants able to identify multiple new fraud methods [2] - The "Convenience Market" attracted many residents, where financial knowledge was integrated into daily services, such as haircuts and knife sharpening, demonstrating practical applications of digital payment methods [2][3] Group 3 - The initiative emphasizes that the vitality of financial technology lies in serving the public, with plans to introduce a "Mobile Financial Technology Service Vehicle" to further engage with community needs [3]

Core Insights - The traditional KTV industry is struggling with price wars and homogenization, while the company has successfully launched a self-service KTV model, creating a new wealth opportunity with its AI-driven SaaS system [1][13] - The company has signed over 180 stores and opened more than 80, showcasing the disruptive potential of its system in the KTV sector [1][11] Group 1: System Development and Market Penetration - The company introduced the first self-service KTV SaaS system in China, integrating AI, Internet, IoT, and SaaS to accelerate KTV smart operations [3] - Collaborations with partners like Que Shiying and Fan Mai have led to successful store openings, validating the system's adaptability and operational efficiency [5] - The system has undergone continuous upgrades, enhancing user experience and operational efficiency, leading to explosive growth in brand presence [9][11] Group 2: Market Opportunity and Competitive Advantage - The self-service KTV model significantly reduces costs, with initial investments being only 1/5 of traditional models and operational costs dropping by 70%, allowing for a payback period of approximately 12 months [13] - The self-service KTV market has a penetration rate of less than 5%, indicating a vast untapped market potential worth trillions [13] - Government support for nighttime economy and cultural consumption upgrades further boosts the market prospects for self-service KTVs [13] Group 3: Success Stories and Replication Potential - Brands like Fan Mai and Mai Li Space have rapidly expanded their store counts by leveraging the system's capabilities, demonstrating its effectiveness in various market segments [16] - The system's modular design and comprehensive support enable even newcomers to replicate the success of established brands in the industry [16][18] - The company has established itself as a leader in the self-service KTV sector, with a strong service network and proven operational solutions [18]

夏日骄阳似火，东鹏补水啦联合悦动圈推出的"初夏挑战赛"，为运动爱好者打造了一场专属的夏日运动盛会，展 现出品牌深耕年轻市场的创新探索。从运动赛事到影视综艺，从线上互动到线下体验，东鹏补水啦正以更贴近年 轻人的方式，构建起全方位的品牌营销新版图。 东鹏补水啦携手悦动圈发起初夏挑战赛 创新赛制设计，引领夏日运动风潮 此次活动设置了5公里、10公里、50公里和100公里四个挑战级别，让不同运动水平的参与者都能找到适合自己的 目标。比赛时间跨度为整个六月，从6月1日零点开启至6月30日晚23点59分结束，给予参与者充分的挑战时间和自 由选择空间。 活动的奖励设置极具吸引力，完赛者不仅能获得独特的"初夏补水王"数字勋章与证书，还有机会通过抽奖赢取空 气炸锅、东鹏补水啦产品礼盒、定制篮球、运动毛巾以及悦动圈商城优惠券等丰富奖品。数字化与实物奖励相结 合的方式，既满足了年轻人对虚拟荣誉的追求，也提供了实用的物质激励。 "补水啦"植入《蛮好的人生》剧照 综艺营销领域，品牌重点布局体育运动类节目。在《哎呀好身材》《我在横店打篮球》等节目中，东鹏补水啦 以"运动伙伴"的定位出现，通过展示运动员补充能量的真实场景，直观传达产品功效 ...

Core Insights - Quantum Song, a well-known comprehensive service provider in China, is strategically upgrading its mission and vision to address the diverse needs of the elderly population, marking a solid step into the silver economy sector [1] - The founder, Li Peng, emphasized the company's commitment to understanding the changing needs of the elderly and aims to enhance their life experience through high-quality services, transitioning from a single education focus to a comprehensive service model [1] Group 1 - The company is leveraging a "online + offline" integrated service platform to develop three main business areas: online education, offline study tours, and health consumer products, creating a comprehensive ecosystem that covers learning, living, and nutrition [6] - The brand Zhiqiu Tang was established as a key vehicle for Quantum Song's deep engagement in the silver economy, adhering to the philosophy of "respecting health through natural sourcing" and focusing on the concept of food as medicine [6] - Zhiqiu Tang aims to achieve three goals: promoting healthier living through quality products, achieving better health through scientific dietary therapy, and fostering cultural heritage to enhance longevity [6] Group 2 - Quantum Song is reinforcing its strategic depth in the health consumption sector through robust financial management and continuous service innovation, embodying its mission of "supporting a beautiful and long-lasting life" [6] - The company is progressing towards its vision of becoming "the most beloved and trusted long-term partner for adults" by building a service ecosystem that combines fun, affordability, and convenience [6]

Core Viewpoint - The Jiangsu branch of the Construction Bank organized a "High School Entrance Examination Support Team" to provide assistance and care for students during the examination period, offering essential supplies and services to ensure a smooth experience for both students and their families [1][5][11]. Group 1: Support Services - The "Laborer’s Harbor" transformed into "High School Entrance Examination Supply Stations," providing emergency exam supplies, water, and shade for students and their families at various examination sites [1][3][5]. - A total of 14 "Love Assistance" mobile stations were set up in Nanjing, offering free emergency exam stationery and refreshments for waiting parents [1]. - The support included setting up rest areas, providing psychological relief for anxious parents, and distributing essential items like umbrellas, water, and stationery [5][13]. Group 2: Community Engagement - Volunteers actively engaged with students and parents, offering words of encouragement and distributing supplies such as water, umbrellas, and emergency stationery [3][9][12]. - The initiative also included educational components, such as financial literacy sessions for parents to prevent fraud during the examination period [11]. Group 3: Overall Impact - The support efforts reached multiple locations across Jiangsu, including cities like Wuxi, Xuzhou, and Huai'an, with over 300 items distributed to help alleviate stress for students and their families [8][12]. - The Construction Bank's commitment to supporting students during this critical time reflects its dedication to community service and engagement [15].

6月6日至9日，2025年江苏省老字号"三进三促"活动暨第七届中国(江苏)老字号博览会在南京国际博览中心隆重举行。本次博览会由江苏省商务厅、省发展 改革委、省工业和信息化厅、省文化和旅游厅、省市场监管局、省地方金融监督管理局等单位联合主办，以"国货潮品新消费"为主题，聚焦老字号焕新升 级、文化赋能、科技融合等重点内容。来自苏州的子冈珠宝作为代表性老字号企业之一，以原创设计新品亮相展会，并凭借其独特的文创表达与非遗技艺体 验活动，赢得现场高度关注。 本次展会中，子冈珠宝首发原创文创系列"金临旺·麒麟回首"金饰产品，由子冈珠宝艺术总监、中国珠宝首饰设计大师程学林先生领衔设计。作品设计灵感 源自中国传统文化中的瑞兽麒麟，并融合"麒麟回头，万事无忧"传统寓意，将"金临旺、长平安、永富贵"凝于一体。整个系列通过将元宝、金砖、金币分别 嵌于"金""临""旺"三个字形中，以清代官服图腾"麒麟回头"为视觉母本，将历史元素注入现代美学，寓意吉祥圆满。 值得一提的是，此系列产品不仅在设计语言上传承传统文化精髓，更在制作工艺上实现科技与匠艺的深度融合。子冈珠宝率先引入"智能金工机+人工精 雕"复合工艺流程，运用数控微雕技术对黄金细 ...

Core Insights - The company is actively promoting employee health through the implementation of the "Eight Section Brocade" fitness activity, aligning with the national strategy of promoting fitness and the "Healthy China" concept [1][2] - The initiative has fostered a positive workplace atmosphere and enhanced both physical and mental well-being among employees, leading to increased team cohesion [1][2] Group 1: Employee Health Initiatives - The "Eight Section Brocade" exercise is introduced to address issues related to prolonged sitting and stress among employees, providing a simple and effective way to relieve fatigue and improve circulation [1] - Employees are encouraged to participate in daily sessions, transitioning from a mindset of obligation to one of enthusiasm for fitness [1] Group 2: Family and Community Engagement - The company has developed a "workplace-family" health promotion model, encouraging employees to involve their families in fitness activities, thereby creating a health ecosystem [2] - Employees are motivated to act as "health ambassadors," promoting the practice of "Eight Section Brocade" within their families, which reflects a holistic approach to health [2] Group 3: Impact on Business Performance - The ongoing fitness activities have contributed to alleviating common workplace ailments, such as neck and shoulder pain, and have improved overall employee morale and productivity [2] - Enhanced team collaboration and communication have been observed, leading to improved service quality and positive customer feedback during recent business challenges [2] Group 4: Future Directions - The company plans to continue enhancing health management initiatives and explore innovative forms of workplace exercise to further promote employee well-being and business development [2]