Financial Performance - The company has a performance assessment that includes financial metrics such as ROE and net profit margin, which hold significant weight in evaluations [3] - In 2023, the sales expense ratio began to decline due to the integration and adjustment of marketing models, with expectations for further control in 2024 [6] Business Growth and Strategy - Shanghai Pharmaceuticals has covered 25 provinces and continues to seek expansion opportunities [3] - The company has established a CSO team that has promoted over 60 products for foreign enterprises, with Sanofi packaging more than one-third of its products with the company, exceeding 5 billion [4] - The global weight loss market is projected to reach $200 billion by 2025, with China’s market size nearing $15 billion in 2023 [4] Innovation and R&D - The company has a pipeline of 68 new drugs, including 55 innovative drugs and 13 modified new drugs, with three innovative drugs already submitted for market approval [5] - The company has initiated clinical trials primarily through its in-house clinical registration team, significantly speeding up the process compared to outsourcing [5] Traditional Chinese Medicine (TCM) - The TCM segment performed well last year, with revenue approaching 10 billion, primarily from proprietary Chinese medicines [5] - Future strategies include strengthening the terminal marketing system and conducting real-world studies to further validate clinical value [5] Cost Reduction and Efficiency - The industrial sector focuses on quality, cost optimization, smart manufacturing, and green development, with ongoing efforts to enhance production efficiency [6] - Six major initiatives are in place to improve capacity utilization and reduce costs, including optimizing production layout and enhancing personnel efficiency [6]

Investment Rating - The report maintains a "Buy" rating for Shanghai Pharmaceuticals-A with a target price of RMB 22.37, down from the previous target of RMB 23.63, indicating a potential upside of 27% from the current price of RMB 17.62 [1][6][14]. Core Insights - The company experienced steady revenue growth in 2023, achieving revenue of RMB 263 billion, a year-on-year increase of 12%. However, the net profit of RMB 3.768 billion fell short of expectations, declining by 33% year-on-year [1][2]. - The pharmaceutical distribution segment showed strong performance with revenue of RMB 233.76 billion, up 14% year-on-year, while the pharmaceutical manufacturing segment saw a slight decline in revenue [1][2]. - The innovative drug pipeline is entering a harvest phase, with several new drugs in various stages of clinical trials and applications [2][14]. Financial Summary - In 2023, the company reported a net profit of RMB 3.768 billion, down 33% from the previous year, with a corresponding EPS of RMB 1.02, a decrease of 35% [1][8]. - The operating cash flow for 2023 was RMB 5.232 billion, reflecting a 10% increase year-on-year [1][8]. - The report forecasts a compound annual growth rate (CAGR) for revenue and net profit of 11% and 19%, respectively, from 2023 to 2026 [1][2]. Segment Performance - The pharmaceutical distribution segment generated revenue of RMB 233.76 billion, with a gross margin of 6.3%, down 0.27 percentage points year-on-year [1][9]. - The pharmaceutical manufacturing segment reported revenue of RMB 26.26 billion, a decrease of 2% year-on-year, with a gross margin of 58.5% [2][9]. - The retail segment achieved revenue of RMB 9.11 billion, up 10% year-on-year, but with a declining gross margin of 12.0% [9]. Earnings Forecast Adjustments - Due to lower-than-expected performance in 2023, the report has revised down the earnings forecasts for 2024 and 2025, with EPS estimates adjusted to RMB 1.56 and RMB 1.66, representing decreases of 18% and 19% respectively [3][11][13].

2024 年4 月3 日 医药: 超配 证券研究报告 / 业绩点评报告 上海医药-A (601607 CH, 买入, 目标价: RMB22.37) 2023 年营收稳健增长；创新药迎来收获期 目标价: RMB22.37 当前股价: RMB17.62 • 2023 年营收稳健增长，2023 年股息率为2.1%（最近三年平均为2.4%）。 股价上行/下行空间 +27% 52周最高/最低价 (RMB) 23.98/15.36 • 医药商业：CSO、疫苗、器械大健康等业务为未来增长点；医药工业：创新药管线进 市值 (US$mn) 11,031 入收获期。 当前发行数量(百万股) 2,842 • 维持买入评级，SOTP 目标价下调至22.37 元。 三个月平均日交易額 31 (US$mn) 流通盘占比 (%) 68 2023 年营收稳健增长，净利润低于我们预测：公司发布年报，2023 年实现营收2,630 亿 主要股东 (%) 元，同比增长12%；归母净利润37.68 亿元，同比下降33%；扣非归母净利润35.96 亿 香港中央结算 19 元，同比下降16%。其中4Q23 实现营收628 亿元，同比9%；归母净亏损28 ...

Financial Performance - Shanghai Pharmaceuticals reported a revenue of RMB 100 billion for the fiscal year 2023, representing a year-on-year growth of 15%[3]. - The company achieved a net profit of RMB 8 billion, which is an increase of 10% compared to the previous year[3]. - In 2023, Shanghai Pharmaceuticals reported a revenue of RMB 260,295,089 thousand, representing a year-on-year increase of 12.2% from RMB 231,981,300 thousand in 2022[23]. - The company's profit before tax for 2023 was RMB 7,054,297 thousand, a decrease of 20% compared to RMB 8,808,353 thousand in 2022[23]. - The net profit attributable to the owners of the company for 2023 was RMB 3,768,000 thousand, a decline from RMB 5,617,152 thousand in 2022, representing a decrease of 32.9%[23]. - The gross margin for the year was reported at 40%, maintaining stability compared to the previous year[3]. - The company reported a significant increase in other income, which rose by 101.43% to ¥793.16 million, primarily due to increased government subsidies[95]. - The company's operating revenue for the reporting period reached ¥260.30 billion, an increase of 12.21% compared to ¥231.98 billion in the same period last year[95]. - Operating costs rose to ¥228.97 billion, reflecting a 13.63% increase from ¥201.49 billion, driven by higher sales revenue[95]. Market Expansion and Product Development - Shanghai Pharmaceuticals plans to launch three new products in 2024, targeting a market expansion of 25% in the healthcare sector[3]. - The company aims to expand its market presence in Southeast Asia, with a projected growth rate of 30% in that region[3]. - The company is considering strategic acquisitions to enhance its product portfolio, with a budget of RMB 2 billion allocated for potential mergers[3]. - The company has 68 new drug pipelines in various stages, including 55 innovative drugs and 13 modified new drugs, with 3 innovative drugs submitted for pre-NDA or market application[40]. - The company has 16 ongoing projects in its rare disease platform, focusing on innovative drugs and urgently needed medications[75]. - The company is actively developing I001 for inflammatory bowel disease and diabetic nephropathy, with ongoing patient recruitment[47]. - The company has completed the enrollment for Phase II clinical trials of B013, a new drug for triple-negative breast cancer, with good safety results reported[51]. - The company has 6 projects in Phase III clinical trials, including BCD-100 for cervical cancer and non-small cell lung cancer[42]. Research and Development - The company has invested RMB 1.5 billion in R&D for new technologies, focusing on innovative drug development[3]. - Research and development investment totaled RMB 2.602 billion, with R&D expenses of RMB 2.204 billion, a year-on-year increase of 4.35%[37]. - The total R&D investment for the period amounted to RMB 260,226,000, representing 9.91% of operating revenue[106]. - The company aims to enhance its R&D capabilities by building high-quality teams and establishing open R&D platforms in collaboration with universities and research institutions[132]. - The company is increasing R&D investment and optimizing innovation resource allocation to enhance its competitive edge in innovative drug development[135]. Corporate Social Responsibility and Governance - The company emphasized its commitment to corporate social responsibility, aiming to improve public health quality through various initiatives[3]. - The company’s ESG efforts have been recognized with an AA rating from MSCI and Wind, placing it among the leading peers in the industry[73]. - The company aims to enhance corporate governance and retain talent through the stock option incentive plan, aligning the interests of management with the long-term development of the company[173]. Strategic Partnerships and Collaborations - The company established strategic partnerships with Shanghai Jiao Tong University and China Pharmaceutical University to enhance its innovation capabilities in drug research[27]. - The company has formed a strategic partnership with Sanofi for nationwide multi-channel cooperation, showcasing its strength as China's largest drug and medical device import and export platform[29]. - The company has completed the acquisition of Hunan Runji Pharmaceutical and Zhengda Tianqing's commercial segment, expanding its domestic pharmaceutical distribution network[63]. International Development - The company is actively expanding its international business, with steady growth in international revenue and substantial progress in product registrations[62]. - The company has made significant progress in the Philippines market, with the registration of Rosuvastatin Calcium Tablets and two other products approved for pre-review[64]. - The company plans to accelerate its international development, focusing on generic drugs and innovative drug layouts, while seeking overseas acquisition opportunities[132]. Stock Options and Incentive Plans - The stock option incentive plan approved in December 2019 involved granting 25,600,000 stock options to 210 incentive targets[168]. - The company aims to enhance corporate governance and retain talent through the stock option incentive plan, aligning the interests of management with the long-term development of the company[173]. - The total number of A-share stock options granted under the incentive plan is 24,355,720 shares, which does not exceed 1% of the company's total issued shares as of the report date[177]. - The exercise price for the stock options granted under the incentive plan is set at RMB 18.41 per A-share[183]. - The stock options granted under the incentive plan have a maximum validity period of 60 months from the grant registration date[185].

证券代码：601607 证券简称：上海医药 编号：临2024-033 上海医药集团股份有限公司 关于 2019 年 A 股股票期权激励计划首次授予股票期权第三 个行权期及预留股票期权第二个行权期 2024 年第一季度自主行权结果公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担个别及连带责任。 重要内容提示： 一、本次股权激励计划已履行的相关审批程序 1、2019 年 9 月 30 日，公司召开第七届董事会第五次会议及第七届监事会 第三次会议，审议通过了《关于 2019 年股票期权激励计划（草案）及其摘要的 议案》（以下简称"《股票期权激励计划（草案）》"）、《关于 2019 年股票期权激 励计划实施考核管理办法的议案》（以下简称"《考核管理办法》"）、《关于提请股 东大会授权董事会办理 2019 年股票期权激励计划相关事宜的议案》。公司董事中 作为激励对象的关联董事左敏先生、李永忠先生及沈波先生均已回避表决。公司 1 上海医药集团股份有限公司（以下简称"上海医药"或"公司"）2019 年 A 股股票期权激励计划（"本次股权激励计划" ...

国投证券股份有限公司 关于上海医药集团股份有限公司与上海上实集团财务有限公司 2023 年度《金融服务协议》暨关联交易的核查意见 国投证券股份有限公司（以下简称"国投证券"或"保荐机构"）作为上海 医药集团股份有限公司（以下简称"上海医药"或"公司"）持续督导工作的保 荐机构，根据《证券发行上市保荐业务管理办法》《上海证券交易所上市公司自 律监管指引第 11 号——持续督导》《上海证券交易所上市公司自律监管指引第 5 号——交易与关联交易》等相关规定，对上海医药与上海上实集团财务有限公司 （以下简称"财务公司"）2023 年度《金融服务协议》暨关联交易的事项进行了 核查，核查的具体情况如下： 一、财务公司基本情况与关联关系介绍 （一）关联方关系介绍 上海医药与财务公司的控股股东均为上海上实（集团）有限公司（以下简称 "上海上实"），因此公司与财务公司构成关联关系。 （二）关联人基本情况 财务公司由上海上实（股东一）、上海医药集团股份有限公司（股东二）、 上海上实资产经营有限公司（股东三）以及上海实业东滩投资开发（集团）有限 公司（股东四）合资成立。2014 年 9 月 1 日在中华人民共和国上海市注册成立 的 ...

国投证券股份有限公司 一、交易情况概述 （一）交易目的 公司进出口业务及其他外汇相关业务涉及结算币种多样，其中主要包括美元、 港币、欧元、日元、澳大利亚元、新西兰元、人民币等，当汇率出现较大波动时， 汇兑损益将对公司生产经营产生一定影响。因此，为有效规避和防范外汇市场风 险，平滑汇率波动对公司经营业绩造成的影响，合理降低财务费用，公司及合并 报表范围内下属子公司 2024 年拟根据实际情况，围绕日常经营业务，适时开展 金融衍生品交易业务。 （二）交易金额 关于上海医药集团股份有限公司 2024 年度开展金融衍生品业务的核查意见 国投证券股份有限公司（以下简称"国投证券"或"保荐机构"）作为上海 医药集团股份有限公司（以下简称"上海医药"或"公司"）持续督导工作的保 荐机构，根据《证券发行上市保荐业务管理办法》《上海证券交易所上市公司自 律监管指引第 1 号——规范运作》《上海证券交易所上市公司自律监管指引第 11 号——持续督导》以及《上海证券交易所股票上市规则》等相关规定，对上海医 药 2024 年度开展金融衍生品交易业务进行了核查，具体情况如下： 根据业务需求量，公司及公司下属子公司拟开展金融衍生品业务金 ...

国投证券股份有限公司 关于上海医药集团股份有限公司非公开发行 A 股股票 持续督导之保荐总结报告书 国投证券股份有限公司（以下简称"国投证券"或"保荐机构"）作为上海 医药集团股份有限公司（以下简称"上海医药"或"公司"）非公开发行 A 股股 票项目的保荐机构，履行持续督导职责期限至 2023 年 12 月 31 日。目前持续督 导期已经届满，现根据《证券发行上市保荐业务管理办法》《上海证券交易所上 市公司自律监管指引第 11 号——持续督导》等相关规定，出具本保荐总结报告 书。 一、保荐机构及保荐代表人承诺 1、保荐总结报告书和证明文件及相关资料的内容不存在虚假记载、误导性 陈述或重大遗漏，保荐机构及保荐代表人对其真实性、准确性、完整性承担法律 责任。 2、保荐机构及保荐代表人自愿接受中国证券监督管理委员会（以下简称"中 国证监会"）对保荐总结报告书相关事项进行的任何质询和调查。 3、保荐机构及保荐代表人自愿接受中国证监会按照《证券发行上市保荐业 务管理办法》的有关规定采取的监管措施。 二、保荐机构基本情况 | 保荐机构名称 | 国投证券股份有限公司 | | --- | --- | | 注册地址 | 深圳市 ...

国投证券股份有限公司 根据《证券法》《证券发行上市保荐业务管理办法》《上海证券交易所股票上 市规则》和《上海证券交易所上市公司自律监管指引第 11 号——持续督导》等 有关法律法规的规定以及与上海医药签订的保荐协议，国投证券股份有限公司 （以下简称"国投证券"或"保荐机构"）作为保荐机构，对上海医药进行持续 督导，持续督导期为 2022 年 4 月 8 日至 2023 年 12 月 31 日。2023 年度国投证 券对上海医药的持续督导工作情况总结如下： | 序号 | 事项 | 督导情况 | | --- | --- | --- | | 1 | 建立健全并有效执行持续督导工作制度，并针 对具体的持续督导工作制定相应的工作计划 | 保荐机构已建立健全并有效执行 了持续督导制度，并制定了相应 | | | | 的工作计划 | | 2 | 根据中国证监会相关规定，在持续督导工作开 | 保荐机构已与公司签订《保荐协 | 一、持续督导工作概述 1 | | 始前，与上市公司或相关当事人签署持续督导 | 议》，相关协议已明确了各方在 | | --- | --- | --- | | | 协议，明确双方在持续督导期间的权利义务， ...

国投证券股份有限公司 关于上海医药集团股份有限公司 2024 年度对外担保计划的核查意见 国投证券股份有限公司（以下简称"国投证券"或"保荐机构"）作为上海 医药集团股份有限公司（以下简称"上海医药"或"公司"）持续督导工作的保 荐机构，根据《证券发行上市保荐业务管理办法》《上海证券交易所上市公司自 律监管指引第 1 号——规范运作》《上海证券交易所上市公司自律监管指引第 11 号——持续督导》以及《上海证券交易所股票上市规则》等相关规定，对上海医 药 2024 年度对外担保计划进行了核查，核查的具体情况如下： 一、担保情况概述 为适应上海医药业务发展需要，满足公司及下属子公司担保融资需求，2024 年度上海医药及下属子公司对外担保额度约合人民币 1,930,528.50 万元（包括人 民币 1,891,284 万元、美金 3,000 万元、新西兰元 4,000 万元，外币按 2023 年 12 月 31 日中国人民银行公布的中间价折算），包括：（一）上海医药本部 2024 年度 对外担保计划额度为美金 3,000 万元、新西兰元 4,000 万元；（二）上海医药的控 股子公司 2024 年度对外担保计划额度 ...