康龙化成(北京)新药技术股份有限公司 关于 2022 年 A 股限制性股票激励计划 第三个归属期归属结果暨股份上市的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 重要内容提示： 证券代码：300759 证券简称：康龙化成 公告编号：2026-009 1、本次归属股票数量及归属人数：本次归属限制性股票的激励对象共计 276 名，归属限制性股票数量合计 565,698 股，占公司目前总股本的 0.0308%； 2、本次限制性股票归属上市流通时间为 2026 年 1 月 29 日。 康龙化成（北京）新药技术股份有限公司（以下简称"公司"或"本公司"） 于 2025 年 8 月 21 日召开的第三届董事会第十五次会议、第三届监事会第十三次 会议，审议通过了《关于 2022 年 A 股限制性股票激励计划第三个归属期归属条 件成就但股票暂不上市的议案》。近日公司办理了 2022 年 A 股限制性股票激励 计划（以下简称"本次激励计划"）第三个归属期归属股份的登记工作，现将有 关事项说明如下： 一、本次激励计划实施情况概要 （一）本次激励计划简述 1、授予限制性股票 ...

证券代码：300759 证券简称：康龙化成 公告编号：2026-008 康龙化成(北京)新药技术股份有限公司 关于 2021 年 A 股限制性股票激励计划 第四个归属期归属结果暨股份上市的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 重要内容提示： 1、本次归属股票数量及归属人数：本次归属限制性股票的激励对象共计 44 名，归属限制性股票数量合计 81,643 股，占公司目前总股本的 0.0044%； 一、本次激励计划实施情况概要 （一）本次激励计划简述 1、授予限制性股票的股票来源及授予数量 本次激励计划的标的股票来源为公司向激励对象定向发行的本公司人民币 A 股普通股股票。 2、本次限制性股票归属上市流通时间为 2026 年 1 月 29 日。 康龙化成（北京）新药技术股份有限公司（以下简称"公司"或"本公司"） 于 2025 年 8 月 21 日召开的第三届董事会第十五次会议、第三届监事会第十三次 会议，审议通过了《关于 2021 年 A 股限制性股票激励计划第四个归属期归属条 件成就但股票暂不上市的议案》。近日公司办理了 2021 年 A 股限 ...

截至2026年1月27日 10:12，中证医药及医疗器械创新指数(931484)成分股方面涨跌互现，三生国健领涨 8.29%，大博医疗上涨6.58%，特宝生物上涨2.64%；神州细胞领跌。医疗创新ETF(516820)最新报价0.36 元。 国信证券指出，2025年创新药板块呈现显著超额收益，核心驱动力来自BD出海密集落地、临床数据持 续超预期及政策端支持；展望2026年，具备全球竞争力、差异化创新能力及已实现高质量授权的创新药 企业仍具长期配置价值。荣昌生物PD-1/VEGF双抗RC148获艾伯维6.5亿美元首付款、最高达49.5亿美元 的重磅授权交易，进一步验证中国ADC平台型企业的国际商业化能力。 医疗创新ETF紧密跟踪中证医药及医疗器械创新指数，中证医药及医疗器械创新指数从医药卫生行业的 上市公司中，选取30只盈利能力较好且具备一定成长性和研发创新能力的上市公司证券作为指数样本， 以反映兼具盈利性与成长性的医药及医疗器械上市公司证券的整体表现。 数据显示，截至2025年12月31日，中证医药及医疗器械创新指数(931484)前十大权重股分别为药明康 德、恒瑞医药、迈瑞医疗、爱尔眼科、片仔癀、新和成、华 ...

格隆汇1月27日丨根据联交所最新权益披露资料显示，2026年1月22日，康龙化成(03759.HK)获Norges Bank在场内以每股均价22.82港元增持1025万股，涉资 约2339.05万港元。 | 表格序號 | 大股東/董事/最高行政人員名稱作出披露的 買入 / 賣出或涉及的 每般的平均價 | | | | 持有權益的股份數目 佔已發行的 有關事件的日期 | | | --- | --- | --- | --- | --- | --- | --- | | | | 原因 | 股份數目 | | (請參閱上述 * 註 | 有投票權股 (日 / 月 / 年) | | | | | | | | 份自分比 | | CS20260123E00561 | Norges Bank 10.250.000(L | 1001(L) | | HKD 22.8200 | 21.474.224(L) | 6.09(L)22/01/2026 | 增持后，Norges Bank最新持股数目为2147.422万股，持股比例由3.81%上升至6.09%。 ...

智通财经APP获悉，香港联交所最新资料显示，1月22日，Norges Bank增持康龙化成(03759)1025万股， 每股作价22.82港元，总金额约为2.34亿港元。增持后最新持股数目约为2147.42万股，最新持股比例为 6.09%。 ...

香港联交所最新资料显示，1月22日，Norges Bank增持康龙化成（300759）(03759)1025万股，每股作价 22.82港元，总金额约为2.34亿港元。增持后最新持股数目约为2147.42万股，最新持股比例为6.09%。 ...

Investment Rating - The report maintains a "Cautious" investment rating for the pharmaceutical sector, highlighting the need to focus on specific investment opportunities within the CXO segment and AI pharmaceutical developments [2]. Core Insights - The pharmaceutical sector is currently experiencing a mixed performance, with the Shenwan Pharmaceutical and Biological Index down by 0.4% this week, ranking 27th among 31 Shenwan primary sub-industries [3][5]. - The overall valuation of the pharmaceutical sector stands at 30.3 times earnings, placing it 12th among 31 Shenwan primary industries [5]. - The report emphasizes the ongoing transformation of the pharmaceutical retail industry towards comprehensive health services, driven by a joint opinion from nine government departments [13][14]. - New drug development remains active, with significant advancements such as the NDA acceptance for Bai Li Tianheng's EGFR×HER3 dual antibody ADC and Moderna's personalized mRNA cancer vaccine showing promising results [15][16]. Market Performance - The Shenwan Pharmaceutical and Biological Index decreased by 0.4%, while the Shanghai Composite Index increased by 0.84% [3]. - Among the secondary sectors, the performance varied, with raw materials (+2.4%) and offline pharmacies (+9.7%) showing positive growth, while medical research outsourcing (-4.0%) and chemical preparations (-1.7%) faced declines [5][12]. Industry Dynamics - By the end of 2025, China's total population is projected to be approximately 1.40489 billion, with a birth rate of 7.92 million, indicating a slight decrease in population compared to the previous year [12]. - The pharmaceutical retail industry is undergoing a critical transformation, with a focus on enhancing pharmacy services and optimizing industry structure [13][14]. - The report outlines five key measures to promote high-quality development in the pharmaceutical retail sector, including improving pharmacy service capabilities and enhancing emergency service functions [14]. Company Developments - Bai Li Tianheng's NDA for the EGFR×HER3 dual antibody ADC has been accepted, targeting esophageal squamous cell carcinoma [15]. - Moderna's personalized mRNA cancer vaccine has shown a 49% reduction in recurrence or death risk compared to monotherapy with Keytruda [16]. - The launch of Insilico Medicine's large language model training framework aims to enhance drug discovery capabilities significantly [16]. Financing Dynamics - OpenEvidence, an AI medical platform, successfully raised $250 million in Series D funding, achieving a post-money valuation of $12 billion [22]. - Qixing Pharmaceuticals completed a $287 million D1 round of financing to advance its clinical pipeline for cardiovascular and metabolic diseases [22]. Performance Forecasts - Several companies in the pharmaceutical sector have released optimistic earnings forecasts for 2025, indicating a clear industry trend [2]. - Notable companies to watch include WuXi AppTec, Kanglong Chemical, and Tigermed, among others, as they are expected to benefit from the ongoing industry developments [2].

Investment Rating - The report indicates a cautious outlook on the pharmaceutical sector, with a focus on investment opportunities in the CXO segment and AI pharmaceutical development [2][3]. Core Insights - The pharmaceutical sector's performance has been mixed, with the Shenwan Pharmaceutical and Biological Index declining by 0.4% while the Shanghai Composite Index rose by 0.84% [4][6]. - The report highlights the ongoing transformation in China's pharmaceutical retail industry, emphasizing the shift from traditional drug sales to comprehensive health services, supported by government initiatives [13][14]. - New drug development remains active, with several significant clinical trial applications and promising results from innovative therapies, particularly in oncology and AI-driven drug discovery [15][16][17]. Market Performance - The Shenwan Pharmaceutical and Biological Index ranked 27th among 31 Shenwan first-level sub-industries, with a current overall valuation of 30.3 times earnings, placing it 12th among all first-level industries [4][6]. - Various sub-sectors showed differing performance, with raw materials (+2.4%) and offline pharmacies (+9.7%) performing well, while medical research outsourcing (-4.0%) and chemical preparations (-1.7%) faced declines [6][8]. Recent Key Events - The report notes the significant population dynamics in China, with a total population of approximately 1.40489 billion by the end of 2025, which continues to support economic growth [12]. - The Ministry of Commerce and other departments have issued guidelines to promote high-quality development in the pharmaceutical retail sector, focusing on enhancing service capabilities and optimizing industry structure [13][14]. - Several companies, including BaiLi Tianheng and Moderna, have made strides in drug development, with notable advancements in cancer therapies and AI applications in pharmaceuticals [15][16][17]. Company Dynamics - The report identifies several companies with promising performance forecasts for 2025, including WuXi AppTec, Kanglong Chemical, and Tigermed, highlighting their potential as investment targets [23][26]. - The AI healthcare platform OpenEvidence successfully raised $250 million in Series D funding, reflecting strong growth and increasing adoption among healthcare professionals [23][24].

Investment Rating - The report maintains a positive investment rating for the pharmaceutical sector [5] Core Views - The report emphasizes three main investment themes for 2026: innovation, overseas expansion, and turnaround impulses, with a focus on BD2.0, small nucleic acids, and supply chain (CXO and upstream) [2][3] - The report suggests that the pharmaceutical sector is currently experiencing a rotation in investment focus, particularly in areas such as brain-computer interfaces, AI integration, small nucleic acids, and medical robotics [3] Summary by Sections Public Fund Holdings Update for Q4 2025 - Overall, the market value of public funds holding pharmaceutical stocks has decreased, with a total market value of 217.6 billion yuan, down by 51 billion yuan from the previous quarter [14] - The pharmaceutical sector's allocation in public funds is 7.96%, a decrease of 1.74 percentage points [19] - Chemical preparations remain the most heavily weighted sub-industry, while allocations to medical devices have increased [14][25] Market Review and Analysis - The pharmaceutical and biotechnology index decreased by 0.39% week-on-week, outperforming the CSI 300 index but underperforming the ChiNext index [1] - The total trading volume in the pharmaceutical sector was 554.24 billion yuan, accounting for 4.00% of the total trading volume in the Shanghai and Shenzhen markets [1] Investment Opportunities - The report identifies specific companies for potential investment, including: - CXO and innovative drug companies such as Tigermed, Zhaoyan New Drug, and Hai Si Ke, which have seen significant increases in fund holdings [16][38] - AI innovative drug companies like Jingtai Holdings and small nucleic acid firms such as Frontier Biotech and Yuyuan Pharmaceutical [3][38] - The report also highlights the importance of exploring CROs, essential drugs, and companies showing signs of bottoming out [3]

机构：招银国际 研究员：Benchen HUANG/Jill WU A vibrant ecosystem built on synergistic business segments. 1) Lab services have been the backbone of Pharmaron. New bookings of lab services increased by >15% YoY in 2024, with a similar trend in 9M25, supporting growth of this segment. 2) Small molecule CDMO services is highly complementary to lab services. Given the commercial-stage projects obtained in 2024 and its rich pipeline dominated (>95%) by early-phase projects, the CDMO segment is poised to see increasing comme ...