Core Viewpoint - The company reported a positive performance in Q1 2025, with revenue and net profit showing significant year-on-year growth, driven by the recovery in innovative drug financing and an increase in new orders [1][2][4]. Revenue Summary - In Q1 2025, the company achieved revenue of 3.099 billion yuan, representing a year-on-year increase of 16.03% [1][2]. - Revenue breakdown by service: - Laboratory services: 1.857 billion yuan (+15.74%) - CMC services: 693 million yuan (+19.05%) - Clinical research services: 447 million yuan (+14.25%) - Large molecule and cell & gene therapy services: 99 million yuan (+7.94%) [2]. Profit Summary - The company reported a net profit attributable to shareholders of 306 million yuan in Q1 2025, reflecting a year-on-year growth of 32.54% [3]. Order and Project Delivery Summary - The company experienced a recovery in new orders, with a year-on-year increase of over 10% in Q1 2025, attributed to the resurgence in innovative drug financing [5]. - Core business is expected to grow steadily, with projected revenue growth of 10%-15% for 2025 [5]. - Specific growth in laboratory services includes a revenue increase of 15.7% and new orders growth of over 10% [5]. Investment Outlook - Projected net profits for the company from 2025 to 2027 are 1.928 billion yuan, 2.148 billion yuan, and 2.389 billion yuan, respectively [6]. - The expected EPS for 2025 is 1.08 yuan per share, with a target price of 27.00 yuan per share based on a 25x PE ratio, suggesting a "Buy-A" investment rating [6].

Summary of the Conference Call for 康龙化成 (Crown Bioscience) Q1 2025 Company Overview - 康龙化成 reported a revenue of 30.96 billion CNY in Q1 2025, representing a year-on-year growth of 15.4% [2][3] - The company maintains its revenue growth guidance for 2025 at 10% to 15% and expects to continue generating positive free cash flow [2][9] Key Financial Performance - The adjusted net profit for Q1 2025 was 3.49 billion CNY, a year-on-year increase of 3.1%, while the net profit attributable to shareholders was 3.06 billion CNY, up 32.5% [3][4] - The laboratory services segment generated 18.57 billion CNY, with a gross margin of 45.5%, up 1.4 percentage points [2][5] - The small molecule CDMO services segment reported revenue of 6.93 billion CNY, with a gross margin of 30.4%, an increase of 2.5 percentage points [2][5] - Clinical services revenue was 4.47 billion CNY, with a gross margin of 11.8%, up 2.5 percentage points [2][5] - The revenue from large molecule and cell & gene therapy services was 99 million CNY, showing a year-on-year growth of 7.9% [2][5] Revenue Breakdown by Region and Client Type - Revenue from Chinese laboratories and factories grew by 15.7%, accounting for 88% of total revenue; overseas revenue increased by 18.3%, making up 12% [2][6] - North American client revenue rose by 16.8%, representing 65% of total revenue; European client revenue increased by 26%, accounting for 18% [2][6] Order Growth and Market Trends - New orders maintained a double-digit growth of over 10% in Q1 2025, continuing the trend from the previous year [2][7] - The CMC business is focused on early clinical stages, with expectations for several large projects to advance into later stages, which will enhance CMC revenue and overall performance [4][23] Strategic Initiatives and Future Outlook - The company is investing in advanced technologies in the biosciences field, including 3D cell culture and organ-on-a-chip models, to stay at the forefront of industry developments [4][12] - The company anticipates that the adjusted net profit growth will accelerate from Q2 2025 onwards as operational efficiencies improve [3][4] - The overall market for laboratory services and biosciences is expected to continue its recovery, with double-digit growth anticipated in both sectors [9][20] Challenges and Considerations - The company faces challenges related to increased operational costs and depreciation due to new capacity coming online in 2024 [4][3] - The impact of geopolitical factors, such as tariffs and the IRA Act, on client R&D and production needs is being monitored, but the company remains optimistic about its growth trajectory [14][19] Conclusion - 康龙化成's Q1 2025 performance reflects strong growth across its segments, with a positive outlook for the remainder of the year, driven by strategic investments and a robust order pipeline [29]

Core Insights - The global and US innovative drug VC&PE financing amounts are expected to grow by 1.93% and 5.29% respectively in 2024, indicating a recovery in the innovative drug financing environment [1] - The demand for research and development in fields such as peptides and ADCs is strong, leading to an increase in outsourcing needs in these areas [1][2] Macro Perspective - The global innovative drug financing environment is recovering, with significant growth in the demand for innovative research in specific fields like peptides and ADCs, which is expected to enhance the CXO industry's outlook [1] - According to Crunchbase, the VC&PE financing for innovative drugs in 2024 shows positive growth, marking an improvement in the financing environment [1] Micro Perspective - CXO listed companies are seeing a recovery in new orders, with many companies like WuXi AppTec, WuXi Biologics, and others reporting a year-on-year increase of over 20% in new orders [3] - The production capacity of domestic CXO companies is mature, ensuring timely delivery of orders, which is expected to lead to double-digit revenue growth for several companies in 2025 [3] Target Companies - Recommended companies to watch include WuXi AppTec (603259.SH, 02359), WuXi Biologics (02269), WuXi AppTec (02268), Kelun Pharmaceutical (002821.SZ, 06821), and others [4]

Investment Rating - The report maintains a "Buy-A" investment rating with a target price of 27.00 CNY per share for the next six months [4][6]. Core Insights - The company has shown a recovery in new orders and project deliveries, leading to improved performance in Q1 2025, with revenue reaching 3.099 billion CNY, a year-on-year increase of 16.03%, and a net profit of 306 million CNY, up 32.54% year-on-year [1][2][3]. Revenue and Profit Growth - The revenue breakdown for Q1 2025 includes laboratory services at 1.857 billion CNY (+15.74%), CMC at 693 million CNY (+19.05%), clinical research services at 447 million CNY (+14.25%), and large molecule and cell & gene therapy services at 99 million CNY (+7.94%) [2][3]. - The company expects a revenue growth of 10%-15% year-on-year for 2025, driven by a recovery in the innovative drug investment and financing sector [3]. Financial Projections - The projected net profits for 2025, 2026, and 2027 are 1.928 billion CNY, 2.148 billion CNY, and 2.389 billion CNY respectively, with an expected EPS of 1.08 CNY per share for 2025 [4][5]. - The report anticipates a steady increase in revenue from 13.792 billion CNY in 2025 to 17.759 billion CNY in 2027 [5][11]. Market Performance - As of April 25, 2025, the company's stock price was 23.19 CNY, with a market capitalization of approximately 41.236 billion CNY [6][7]. - The stock has shown a 12-month absolute return of 27.1% [7].

Group 1: Economic Indicators - In the first quarter, the total profit of industrial enterprises above designated size reached 150.936 billion yuan, a year-on-year increase of 0.8% [4] - The Ministry of Commerce and six other departments announced an optimization of the departure tax refund policy, raising the cash refund limit to 20,000 yuan [4][6] Group 2: Company Earnings - Gujing Gongjiu reported a net profit of 5.517 billion yuan for 2024, a year-on-year increase of 20.22%, and proposed a dividend of 50 yuan per 10 shares [8] - Gree Electric reported a net profit of 32.185 billion yuan for 2024, a year-on-year increase of 10.91%, and proposed a dividend of 20 yuan per 10 shares [8] - Luzhou Laojiao reported a net profit of 13.473 billion yuan for 2024, a year-on-year increase of 1.71%, and proposed a dividend of 45.92 yuan per 10 shares [8] - Yake Technology reported a net profit of 872 million yuan for 2024, a year-on-year increase of 50.41%, and proposed a dividend of 2.6 yuan per 10 shares [8] - Yunda Holdings reported a net profit of 1.914 billion yuan for 2024, a year-on-year increase of 17.77%, and proposed a dividend of 2 yuan per 10 shares [8] Group 3: Significant Corporate Announcements - National City Mining reported a net profit of 612 million yuan for the first quarter of 2025, a year-on-year increase of 18,279.65%, primarily due to increased investment income from the sale of subsidiaries [9] - Zhenghe Ecology signed a strategic cooperation agreement with Yanshan (Hebei) Cultural Tourism Development Group, planning a total investment of 2 billion yuan for a tourism integration project [9] - New Life Fortune announced plans to issue shares and pay cash to acquire 100% of Guangzhou Jinnan Magnetic Materials, which is expected to constitute a major asset restructuring [9] - Chengdi Xiangjiang announced that its subsidiary won a bid for a project with a contract value of 1.632 billion yuan, with a construction period of 92 days [10]

Financial Performance - The company's revenue for Q1 2025 reached ¥3,098,813,569.89, representing a 16.03% increase compared to ¥2,670,740,738.16 in the same period last year[6] - Net profit attributable to shareholders was ¥305,575,186.04, up 32.54% from ¥230,557,834.70 year-on-year[6] - The adjusted net profit attributable to shareholders was ¥349,441,031.17, reflecting a 3.14% increase from ¥338,816,299.13 in the previous year[6] - Total revenue for the period reached CNY 3,098,813,569.89, an increase of 15.9% compared to CNY 2,670,740,738.16 in the previous period[35] - Net profit for the period was CNY 279,654,565.09, representing a 29.5% increase from CNY 215,919,833.12 in the prior period[36] - The company reported a profit before tax of RMB 363,587,000, compared to RMB 268,619,000 in the previous year, an increase of 35.4%[42] - Total comprehensive income for the period reached RMB 389,670,737.53, compared to RMB 162,642,198.05 in the previous period, representing an increase of approximately 139.5%[37] Revenue Breakdown - Revenue from laboratory services was ¥1,857,202,616.77, a 15.74% increase from ¥1,604,576,678.01 year-on-year, with a gross margin of 45.54%[8] - Revenue from CMC (small molecule CDMO) services was ¥693,023,486.59, up 19.05% from ¥582,104,488.92, with a gross margin of 30.44%[8] - Revenue from clinical research services reached ¥447,320,929.08, a 14.25% increase from ¥391,531,326.06, with a gross margin of 11.76%[8] - Revenue from the top 20 global pharmaceutical companies was ¥455,746,000, a 29.05% increase, accounting for 14.71% of total revenue[9] Shareholder Metrics - Basic earnings per share increased by 33.54% to CNY 0.1736, reflecting the growth in net profit attributable to shareholders[14] - Diluted earnings per share rose by 33.51% to CNY 0.1733, also attributed to the increase in net profit[15] - The total number of common shareholders at the end of the reporting period was 79,841[20] - The company announced a profit distribution plan for the year 2024, which is expected to enhance shareholder value[28] Cash Flow and Assets - The company's cash flow from operating activities amounted to ¥852,829,144.27, a 14.38% increase compared to ¥745,630,586.78 in the same period last year[6] - Cash flow from investing activities resulted in a net outflow of RMB 1,212,095,238.52, worsening from a net outflow of RMB 467,094,044.67 in the previous period[40] - Cash flow from financing activities showed a net outflow of RMB 98,926,715.92, an improvement compared to a net outflow of RMB 1,512,600,594.24 last period[41] - The total current assets decreased from CNY 7,608,179,522.72 to CNY 7,384,443,685.17, representing a decline of approximately 2.95%[30] - Cash and cash equivalents decreased from CNY 1,689,916,082.15 to CNY 1,262,763,166.96, a reduction of about 25.3%[30] Expenses and Liabilities - Total operating costs amounted to CNY 2,713,717,115.43, up from CNY 2,439,362,705.75, reflecting a growth of 11.2%[35] - Research and development expenses grew by 30.56% to CNY 122,210,590.15, indicating a continued commitment to R&D investment[18] - Income tax expenses rose by 59.27% to CNY 83,932,205.84, corresponding to the increase in total profit[19] - The total liabilities decreased slightly to CNY 9,686,700,206.35 from CNY 9,704,526,037.38, a reduction of 0.2%[33] Other Financial Metrics - Other comprehensive income increased significantly by 1,370.30% to CNY 98,545,941.98, driven by foreign currency translation differences and cash flow hedging[18] - The company's total non-current assets increased to CNY 16,948,379,035.81 from CNY 16,319,218,798.51, marking a growth of 3.9%[31] - The equity attributable to the parent company increased to RMB 14,042,172 thousand from RMB 13,619,335 thousand, marking a growth of 3.1%[44] - The company's goodwill increased to RMB 2,947,429 thousand from RMB 2,760,736 thousand, reflecting a growth of 6.8%[43]

证券代码：300759 证券简称：康龙化成 公告编号：2025-026 康龙化成（北京）新药技术股份有限公司 关于非执行董事辞职暨 补选公司第三届董事会非执行董事的公告 事会任期届满之日止。 胡柏风先生在任职期间勤勉尽责，致力于公司的规范运作和健康发展，并凭 借自身积累的丰富投资经验，为公司可持续发展提供了诸多宝贵建议，公司董事 会对胡柏风先生在任职期间为公司及董事会所做出的贡献表示衷心感谢！ 特此公告。 康龙化成（北京）新药技术股份有限公司董事会 2025 年 4 月 28 日 2 本公司及董事会全体成员保证信息披露内容的真实、准确和完整，没有虚假 记载、误导性陈述或重大遗漏。 康龙化成（北京）新药技术股份有限公司（以下简称"公司"）于 2025 年 4 月 25 日召开第三届董事会第十四次会议，审议通过了《关于补选公司第三届董 事会非执行董事的议案》。胡柏风先生因本职工作调整，申请辞去公司第三届董 事会非执行董事及董事会战略委员会委员职务（第三届董事会原定任期至 2026 年 6 月 20 日），辞职后胡柏风先生将不再担任公司任何职务。胡柏风先生自愿继 续履行非执行董事及董事会战略委员会委员职责至公司股东 ...

证券代码：300759 证券简称：康龙化成 公告编号：2025-024 康龙化成（北京）新药技术股份有限公司 第三届董事会第十四次会议决议公告 本公司及董事会全体成员保证信息披露内容的真实、准确和完整，没有虚假 记载、误导性陈述或重大遗漏。 一、董事会会议召开情况 康龙化成（北京）新药技术股份有限公司（以下简称"公司"）第三届董事 会第十四次会议于 2025 年 4 月 25 日上午 11：00 以通讯方式召开，本次会议通 知及会议材料于 2025 年 4 月 11 日以邮件形式向全体董事发出。会议应出席董事 8 名，实际出席董事 8 名。本次会议由公司董事长 Boliang Lou 博士主持，公司 部分高级管理人员列席了本次会议。本次会议的召集和召开符合《中华人民共和 国公司法》等有关法律、行政法规、部门规章、规范性文件和《康龙化成（北京） 新药技术股份有限公司章程》的规定。 二、董事会会议审议情况 与会董事审议并以记名投票方式通过了以下议案： （一）审议通过《关于 2025 年第一季度报告的议案》 董事会认为：公司编制的《2025 年第一季度报告》符合法律、行政法规、中 国证监会和深圳证券交易所的规定，报 ...

Financial Performance - The company's revenue for Q1 2025 reached ¥3,098,813,569.89, representing a 16.03% increase compared to ¥2,670,740,738.16 in the same period last year[4] - Net profit attributable to shareholders was ¥305,575,186.04, up 32.54% from ¥230,557,834.70 year-on-year[4] - The adjusted net profit under non-IFRS was ¥349,441,031.17, a 3.14% increase from ¥338,816,299.13 in the previous year[4] - The company's cash flow from operating activities was ¥852,829,144.27, reflecting a 14.38% increase compared to ¥745,630,586.78 in the same period last year[4] - Total operating revenue for the current period reached ¥3,098,813,569.89, an increase of 15.9% compared to ¥2,670,740,738.16 in the previous period[24] - Net profit for the current period was ¥279,654,565.09, compared to ¥215,919,833.12 in the previous period, representing an increase of 29.5%[25] - Basic earnings per share increased by 33.54% year-on-year to RMB 0.1736, reflecting the growth in net profit[12] - Basic earnings per share increased to 0.1736 from 0.1300, marking a growth of 33.1%[26] Revenue Breakdown - Revenue from laboratory services was ¥1,857,202,616.77, with a gross margin of 45.54%, up from 44.14% year-on-year[5] - Revenue from CMC (small molecule CDMO) services increased by 30.44% to ¥693,023,486.59, with a gross margin of 30.44%[5] - Revenue from clinical research services was ¥447,320,929.08, showing an 11.76% increase year-on-year[5] - Revenue from North American clients was ¥200,338.79 million, a 16.81% increase, accounting for 64.65% of total revenue[7] - The company signed new orders with a year-on-year growth of over 10%, particularly in laboratory services and CMC services[7] Assets and Liabilities - Total assets at the end of the reporting period were ¥24,332,822,720.98, a 1.69% increase from ¥23,927,398,321.23 at the end of the previous year[4] - Total current assets decreased to CNY 7,384,443,685.17 from CNY 7,608,179,522.72, representing a decrease of approximately 2.95%[21] - Long-term equity investments increased to CNY 727,361,422.75 from CNY 648,983,149.15, an increase of about 12.06%[21] - Total liabilities increased to CNY 7,206,443,000.00, reflecting a growth of approximately 3.5% compared to the previous period[21] - The total liabilities decreased slightly to ¥9,686,700,206.35 from ¥9,704,526,037.38, a reduction of 0.2%[23] Expenses and Taxation - Research and development expenses increased by 30.56% year-on-year to RMB 122,210,590.15, indicating a continued commitment to R&D investment[12] - Total income tax expenses rose by 59.27% year-on-year to RMB 83,932,205.84, corresponding to the increase in total profit[13] - The company paid $1,398,959,106.45 to employees, an increase from $1,313,660,048.35[29] - The company reported a total tax payment of $146,967,843.36, a decrease from $155,141,776.68[29] Comprehensive Income - Other comprehensive income surged by 1,370.30% year-on-year to RMB 98,545,941.98, mainly due to increases in foreign currency translation differences and cash flow hedging[12] - Other comprehensive income after tax for the current period was ¥110,016,172.44, compared to a loss of ¥53,277,635.07 in the previous period[26] - The company reported a total comprehensive income of ¥389,670,737.53, up from ¥162,642,198.05, indicating a significant increase of 139.5%[26] Cash Flow - Cash inflow from operating activities totaled ¥3,472,049,631.92, compared to ¥3,137,994,335.42 in the previous period, indicating a rise of 10.7%[28] - The net cash flow from operating activities was $852,829,144.27, an increase of 14.4% compared to $745,630,586.78 in the previous period[29] - The total cash outflow from investing activities was $2,181,721,151.04, up from $1,578,554,143.99, resulting in a net cash flow from investing activities of -$1,212,095,238.52[29] - Cash inflow from financing activities was $148,201,518.67, compared to $104,094,412.63 in the previous period, while cash outflow was $247,128,234.59, down from $1,616,695,006.87[29] - The ending balance of cash and cash equivalents was $1,173,579,263.69, down from $4,561,507,266.77[29] Future Plans and Investments - The company plans to invest in new product development and market expansion strategies in the upcoming fiscal year[18] - The company is collaborating with professional institutions for equity investments, indicating a strategic move towards enhancing its investment portfolio[18] - The company has announced a profit distribution plan for the fiscal year 2024, which is expected to be disclosed in detail soon[18] Miscellaneous - The company did not execute any new accounting standards adjustments for the first quarter report[30] - The first quarter report was not audited[30]

证券代码：300759 证券简称：康龙化成 康龙化成（北京）新药技术股份有限公司投资者关系活动记录表 编号：2025-03 问：请问目前中美关税情况对公司是否有影响？ 答：截至目前，美国加征关税对公司业务产生的影响有限。公司主要 是为客户提供研发服务，CMC 涉及的商业化货物出口的业务占比较 小，目前公司并未收到客户或其他合作伙伴向公司反馈关税问题对业 务合作造成影响。对于宏观的不确定性风险，公司会密切关注相关政 策动向。地缘政治背景下，也敬请投资者注意投资风险。 问：小分子 CDMO 产能利用率和毛利率趋势？ 答：从目前公司管线看，预计公司交付项目和收入规模会进一步提 高，产能利用率和毛利率也会同比提升。 | | □特定对象调研 □分析师会议 | | --- | --- | | | □媒体采访 □业绩说明会 | | 投资者关系 活动类别 | □新闻发布会 √路演活动 | | | □现场参观 | | | □其他 | | 参与单位名称及 | | | 人员姓名 | Manulife、TruMed、SinoPac、Library Group、华凯资产管理 | | 时 间 | 年 月 日 2025 4 24 | | ...