（於開曼群島註冊成立之有限公司） 網站：www.sinobiopharm.com （股票編號：1177） 截至二零二五年六月三十日止六個月之中期業績公告 | 財務摘要 | | | | | --- | --- | --- | --- | | | 截至六月三十日止六個月 | | | | | 二零二五年 | 二零二四年 | 變動 | | | 人民幣億元 | 人民幣億元 | % | | 收入 | 175.7 | 158.7 | +10.7% | | 毛利率(%) | 82.5% | 82.1% | +0.4百分點 | | （附註1） 銷售及管理費用佔收入比率(%) | 42.9% | 43.1% | -0.2百分點 | | 研發費用佔收入比率(%) | 18.1% | 16.2% | +1.9百分點 | | 來自持續經營業務之歸屬於母公司持有者盈利 | | | | | （附註2） 財務報表所示 | 33.9 | 14.1 | +140.2% | | （附註3） 基本溢利 | 30.9 | 15.4 | +101.1% | | （附註4） 創新產品收入 | 78.0 | 61.3 | +27.2% | | 佔收入 | ...

8月18日，中国生物制药(01177)盘中上涨2.05%，截至14:42，报7.98元/股，成交7.44亿元。 中国生物制药有限公司是一家创新研究和研发驱动型的医药集团，其主要业务包括医药研发、智能化生 产以及销售，主要产品包括多种生物药和化学药，特别在肿瘤、肝病、呼吸系统、外科/镇痛四大治疗 领域具有优势。公司自从2000年上市以来，在MSCI全球标准指数、恒生指数等多个指数中成为成分 股，连续六年入选《制药经理人》的"全球制药企业TOP50"，核心企业正大天晴药业集团、北京泰德制 药股份有限公司多年位列中国医药工业企业百强榜，公司产品收入占比逐年提升。 截至2024年年报，中国生物制药营业总收入288.66亿元、净利润35.0亿元。 作者：行情君 8月18日，中国生物制药披露2025财年中报。 本文源自：金融界 ...

Group 1 - The market sentiment is bullish, with both Hong Kong and A-shares rising, and the Shanghai Composite Index reaching a 10-year high [1] - The Hang Seng Innovative Drug ETF (159316) increased by over 3.3% today, marking a 76.5% rise since its launch at the end of March this year, achieving a new net asset value high [1] - The Hang Seng Innovative Drug ETF is currently the only ETF tracking the Hang Seng Hong Kong Stock Connect Innovative Drug Index, focusing on high-purity and high-elasticity stocks, including leading innovative drug companies [1] Group 2 - Recent adjustments to the Hang Seng Hong Kong Stock Connect Innovative Drug Index have removed CXO companies, resulting in a 100% concentration of innovative drug components [1] - The Hang Seng Innovative Drug ETF (159316) has attracted significant capital, with a net inflow of 663 million yuan since the second half of this year, bringing its latest scale to 1.258 billion yuan, a 357% increase since its launch [1] - Tianfeng Securities indicates that with the upcoming concentrated release period for innovative drugs and continued government policy support, the development trend and industrial upgrade of the innovative drug sector are becoming clearer [1]

Group 1 - The Chinese government has launched a national venture capital guidance fund with a scale of 1 trillion RMB, focusing on cutting-edge technology sectors such as AI, quantum technology, hydrogen energy storage, and biomanufacturing [1] - The financial asset investment company (AIC) equity investment pilot has expanded to 18 provinces, with Guangdong and Hunan leading the establishment of provincial AIC funds [1] - The optimization of exit paths for technology companies includes IPO adjustments, expansion of S fund trials, and accelerated private equity fund share transfers, enhancing capital circulation certainty [1] Group 2 - The global advanced packaging market is expected to reach $57.1 billion in 2025, with China's market growing from $35.1 billion in 2020 to $69.8 billion in 2024, achieving a compound annual growth rate of 18.7% [2] - The Chinese electric vehicle sector has seen significant growth, with production and sales reaching 6.968 million and 6.937 million units respectively in the first half of 2025, marking year-on-year increases of 41.4% and 40.3% [2] - CATL plans to invest up to 14 billion RMB to establish a core European battery base in Hungary, with an expected annual production capacity of 100 GWh by 2025 [2] Group 3 - Over 40% of the upfront payments exceeding $50 million in BD transactions by multinational pharmaceutical companies have gone to Chinese firms, indicating a strong global presence in the biopharmaceutical sector [3] - Top investment firms such as Sequoia China, Qiming Venture Partners, Hillhouse Capital, and Peakview Capital remain optimistic about the long-term value of the biopharmaceutical industry despite its high-risk nature [3] - The launch of the "Top Venture Capitalists in China" and "Top Venture Capital Institutions in China" lists aims to highlight the strengths of the venture capital ecosystem in China [3]

Group 1 - The overall performance of the Hong Kong stock market is positive, with the innovative drug sector continuing its strong performance from the previous week, supported by solid fundamentals and high trading sentiment [1] - Southbound funds net bought HK stocks worth HKD 35.876 billion on August 15, setting a new record for single-day net inflow since the launch of the mutual market access mechanism in November 2014, with the innovative drug sector receiving a net inflow of HKD 1.042 billion [1] - The Hang Seng Innovative Drug ETF (520500) attracted a net inflow of HKD 117 million from August 11 to August 15, marking the highest weekly net inflow in nearly three months, and its total size reached HKD 1.351 billion, with a year-to-date increase of over 1000% [1] Group 2 - The Hang Seng Innovative Drug ETF (520500) closely tracks the Hang Seng Innovative Drug Index, which selects listed companies in the Hong Kong market related to innovative drug research, development, and production, emphasizing the exclusion of companies primarily engaged in the CXO industry [2] - The index's top five constituent stocks as of August 15 include BeiGene, CanSino Biologics, Innovent Biologics, China National Pharmaceutical Group, and Kelun-Biotech [2] - The national medical security work mid-year meeting held on August 15 emphasized empowering the pharmaceutical industry innovation and implementing measures to support high-quality development of innovative drugs, indicating continued policy support for the innovative drug sector [2] Group 3 - The manager of the Hang Seng Innovative Drug ETF (520500), Huatai-PB Fund, is one of the first ETF managers in China, known for creating leading ETFs such as the CSI 300 ETF and A500 ETF, maintaining an 18-year record of zero errors in ETF operations [3] - As of August 15, the size of the CSI 300 ETF is CNY 393.42 billion, and the A500 ETF is CNY 20.113 billion [3] - The Hang Seng Innovative Drug ETF (520500) was established on December 16, 2024, and supports T+0 trading, enhancing its liquidity advantage [3]

Group 1 - The Hong Kong stock market experienced a rise and then a pullback, with the Hang Seng Index reaching a new high [1] - The National Healthcare Security Administration is publishing a list of drugs that have passed preliminary review for the "2025 National Medical Insurance Directory and Commercial Insurance Innovative Drug Directory," which will enter expert review and negotiation stages [1][2] - The Hong Kong Innovative Drug Selected ETF (520690) saw a nearly 2.5% increase, with a trading volume exceeding 20 million and a turnover rate over 5%, indicating strong market interest [1] Group 2 - The dual-track policy of basic medical insurance and commercial insurance for innovative drugs signals a payment closure model, suggesting that "true innovation is easier to scale" [2] - The performance of innovative drugs is expected to be positively impacted by the dual-track payment system and significant business development opportunities, leading to a systematic revaluation of the Chinese innovative drug sector [2] - The Hang Seng Medical ETF (513060) is benefiting from the dual advantages of technology penetration and market expansion, particularly in AI healthcare and innovative drug companies [3]

(Stock Code: 1177.HK) (RMB bn) 2025 2025 Interim Results Announcement 2025.8.18 Hong Kong CONTENTS Financial Highlights Pipeline Highlights 2 Financial Highlights Both revenue and profit achieved double-digit growth 1.54 3.09 2024 H1 Continuing Operations 2025 H1 Continuing Operations Revenue 15.87 17.57 2024 H1 Continuing Operations 2025 H1 Continuing Operations Profit attributable to owners of the parent (as reported) 1.41 3.39 2024 H1 Continuing Operations 2025 H1 Continuing Operations Profit attributabl ...

Key Points - The top three companies with net inflows from southbound funds are Xinda Biopharmaceutical (01801) with 835 million, China Life (02628) with 403 million, and AIA Insurance (01299) with 373 million [1][2] - The top three companies with net outflows are the Tracker Fund of Hong Kong (02800) with -6.679 billion, Hang Seng China Enterprises (02828) with -2.584 billion, and Anta Sports (02020) with -782 million [1][2] - In terms of net inflow ratio, Canggang Railway (02169) leads with 66.05%, followed by Bosideng (03998) with 49.50%, and Zhengzhou Bank (06196) with 48.61% [1][2] - The companies with the highest net outflow ratios include Skyworth Group (00751) at -52.19%, Anta Sports (02020) at -50.20%, and Ruipu Lanjun (00666) at -44.79% [1][2] Net Inflow Rankings - The top ten companies by net inflow include: - Xinda Biopharmaceutical (01801) with 835 million and a closing price of 95.000 (+8.82%) [2] - China Life (02628) with 403 million and a closing price of 22.800 (+0.71%) [2] - AIA Insurance (01299) with 373 million and a closing price of 76.400 (+3.03%) [2] - Other notable companies include Ideal Automotive (02015) with 365 million and a closing price of 97.150 (+3.30%) [2] Net Outflow Rankings - The top ten companies by net outflow include: - Tracker Fund of Hong Kong (02800) with -6.679 billion and a closing price of 26.080 (+2.35%) [2] - Hang Seng China Enterprises (02828) with -2.584 billion and a closing price of 93.760 (+2.76%) [2] - Anta Sports (02020) with -782 million and a closing price of 90.000 (+0.22%) [2] - Other significant outflows include Alibaba (09988) with -267 million and a closing price of 123.700 (+6.09%) [2] Net Inflow Ratio Rankings - The top companies by net inflow ratio include: - Canggang Railway (02169) with 66.05% and a closing price of 1.310 (-0.76%) [3] - Bosideng (03998) with 49.50% and a closing price of 4.600 (+0.66%) [3] - Zhengzhou Bank (06196) with 48.61% and a closing price of 1.410 (-2.08%) [3] Net Outflow Ratio Rankings - The top companies by net outflow ratio include: - Skyworth Group (00751) with -52.19% and a closing price of 3.260 (+1.24%) [3] - Anta Sports (02020) with -50.20% and a closing price of 90.000 (+0.22%) [3] - Ruipu Lanjun (00666) with -44.79% and a closing price of 12.160 (+5.28%) [3]

Investment Rating - The report maintains an "Overweight" rating for the pharmaceutical and biotechnology industry [1] Core Insights - The upcoming World Conference on Lung Cancer (WCLC) is expected to showcase significant advancements in innovative drugs, generating new business development expectations [1] - The A-share pharmaceutical index has increased by 3% this week and 25% year-to-date, outperforming the CSI 300 by 0.7% and 18.2% respectively [4][9] - The report highlights the strong performance of the pharmaceutical sector, particularly in innovative drugs, research services, and CXO [10][11] Industry Trends - The WCLC will take place from September 6 to September 9, 2025, in Barcelona, featuring over 1,500 presentations, with a significant number from Chinese researchers [17][18] - Chinese innovation is prominently represented, with over 400 submissions, indicating a shift towards the commercialization of innovative drugs [18][19] Stock Performance - Notable stock performances include a 69% increase for Sainuo Medical and a 94% increase for Paig Biological in the H-share market [4][9] - The report provides a detailed overview of stock performance, highlighting both top gainers and losers in the pharmaceutical sector [9][13] Recommendations - The report suggests a focus on specific sub-sectors, ranking them as follows: innovative drugs > research services > CXO > traditional Chinese medicine > medical devices > pharmacies [10] - Specific stock recommendations include companies like Bory Pharmaceutical, Singlera Genomics, and Innovent Biologics based on various therapeutic angles [11][12]

Investment Rating - The investment rating for the pharmaceutical industry is "Positive" (maintained) [4] Core Viewpoints - The report highlights the acceleration of IO tri-antibody therapies entering clinical stages, with significant potential, particularly focusing on Shanghai Yizhong [3][19] - The pharmaceutical index rose by 3.08% from August 11 to August 15, outperforming the CSI 300 index by 0.7% [5] - The report emphasizes the importance of innovative drugs as a clear industry trend, suggesting a focus on companies with strong business development catalysts in the second half of the year [5][29] Summary by Sections Market Performance - The pharmaceutical market showed a positive trend with 279 stocks rising and 200 falling during the week, with notable gains from companies like Sino Medical (+69.13%) and Innovative Medical (+51.53%) [5][30] - The report indicates that the pharmaceutical index has outperformed the CSI 300 index year-to-date by 18.22% [29] Investment Opportunities - The report suggests focusing on innovative drugs, particularly those with low valuation and potential for marginal improvement, including companies like WuXi AppTec, Tigermed, and others [5][29] - It also highlights the increasing importance of tri-antibody therapies in cancer immunotherapy, recommending attention to specific candidates like Shanghai Yizhong's YXC-001 [19][22] Industry Trends - The report notes that the domestic innovative pharmaceutical industry has reached a scale, with traditional companies like Hengrui Medicine and Hansoh Pharmaceutical successfully transitioning to innovation [29][50] - The aging population is driving demand for chronic disease treatments, which is expected to grow steadily [29][50] - The report emphasizes the potential of AI in the pharmaceutical sector, suggesting it could unlock new growth opportunities [29][50] Suggested Focus Areas - The report recommends focusing on innovative drugs and devices, manufacturing overseas, and addressing the needs of an aging population [50][51] - Specific companies to watch include Hengrui Medicine, Shanghai Yizhong, and others in the innovative drug space [52]