Group 1: Product Information - The price of Loxoprofen Sodium Gel Patch in local procurement is approximately [2] - The company believes that Loxoprofen Sodium Gel Patch and Ketoprofen Gel Patch complement each other in the market and do not compete directly [2] - Currently, the Loxoprofen Sodium Gel Patch is in the information submission phase for the 11th batch of centralized procurement [3] Group 2: R&D and Product Development - The company has six external preparations already on the market, including Loxoprofen Sodium Gel Patch and Ketoprofen Gel Patch [3] - Expected approvals in 2025 include Indomethacin Gel Patch and Flurbiprofen Gel Patch, while approvals in 2026 are anticipated for Ketoprofen Patch and others [3] Group 3: Marketing Strategy - The company focuses on continuous R&D investment to enrich its product matrix and leverage first-mover, scale, and cost advantages [3] Group 4: Financial Outlook - The company projects a revenue growth of 10-20% for 2025, with a similar expected increase in net profit [3] - There are risks associated with achieving these targets due to market conditions and industry policies, which may lead to uncertainties in forecasts [3]

Investment Rating - The industry investment rating is "Overweight (Maintain)" [1] Core Viewpoints - The report highlights that the National Medical Insurance Administration's clarification on not using the lowest price as a reference for centralized procurement is expected to continue promoting and optimizing procurement policies, enhancing the participation of pharmaceutical and medical device companies, and balancing quality and innovation in procurement [7] - LZM012 from Livzon Pharmaceutical has successfully reached its primary research endpoint in Phase III clinical trials, showcasing a dual blockade mechanism that comprehensively inhibits inflammatory responses, providing a new solution for achieving deep clearance of skin lesions and sustained relief [7] Summary by Sections Industry Overview - The report focuses on the pharmaceutical and biotechnology industry, emphasizing the recent developments in centralized procurement and the impact on drug pricing and market dynamics [3][4] Clinical Research Highlights - Livzon Pharmaceutical's LZM012 is the first IL-17A/F dual-target inhibitor to complete Phase III clinical trials in China, demonstrating faster onset and superior efficacy compared to the benchmark drug, Secukinumab [4][6] - Key findings from the clinical trial include: - LZM012 achieved a PASI 75 response rate of 65.7% at week 4, outperforming Secukinumab's 50.3% [4] - At week 12, the PASI 100 response rate for LZM012 was 49.5%, compared to 40.2% for Secukinumab, indicating significant efficacy [4] - Long-term efficacy was sustained, with PASI 100 response rates of 75.9% and 62.6% at week 52 for LZM012 under different dosing regimens, surpassing Secukinumab's 61.6% [4] - Safety profiles were comparable between LZM012 and the control group, with similar rates of adverse events [6] Investment Recommendations - The report suggests focusing on companies such as China National Pharmaceutical Group, Hengrui Medicine, and Livzon Pharmaceutical due to their promising developments and the favorable regulatory environment [7]

Investment Rating - The report indicates a positive outlook for the pharmaceutical industry, suggesting an "Overweight" rating, meaning the industry is expected to outperform the overall market [22]. Core Insights - The pharmaceutical sector saw a weekly increase of 1.9%, outperforming the Shanghai Composite Index which rose by 1.7% [2][3]. - The overall valuation of the pharmaceutical sector is currently at 32.0 times PE (Price to Earnings) for 2025E, ranking 6th among 31 primary sectors [5][9]. - The 11th batch of drug procurement has been initiated, with new rules stating that the lowest price will not be the sole reference for selection, emphasizing the need for companies to justify their pricing [10]. - The National Medical Insurance Administration is seeking opinions on how real-world data can support comprehensive value assessments for drugs and medical devices [11]. - Strategic investments are being made in companies like MicroPort Medical and Kanghua Biotech, indicating a trend of consolidation and investment in the sector [11][13]. Summary by Sections Market Performance - The pharmaceutical sector's performance is highlighted with a 1.9% increase, with various sub-sectors showing mixed results, such as vaccines (+6.6%) and medical devices (+4.9%) [5][6]. Key Events - The initiation of the 11th batch of drug procurement with revised selection criteria [10]. - The National Medical Insurance Administration's call for research on real-world data for drug value assessment [11]. - Strategic investments in MicroPort Medical and Kanghua Biotech, indicating a shift in ownership and control within the industry [11][13]. Investment Analysis - The report emphasizes the growth in innovative drug revenues and licensing deals, suggesting a focus on companies with significant product launches and business development expectations [2].

Group 1 - The core viewpoint of the news highlights the active performance of the pharmaceutical sector, particularly in medical devices, smart healthcare, internet healthcare, and CRO, with significant stock price increases for companies like Kangtai Medical, Zhengchuan Co., Hanwang Technology, and Yanhua Intelligent [1] - Kangtai Medical's stock surged by 20%, while other notable gainers included Tianzhihang-U (+13.06%), Yuncong Technology (+11.83%), and Hanshi Technology (+10.02%) [2] - The National Medical Insurance Administration reported that since the start of the 14th Five-Year Plan, 402 types of drugs have been added to the national medical insurance drug list, which now includes a total of 3,159 drugs [3] Group 2 - The National Medical Insurance Administration is optimizing the rules for the 11th batch of drug procurement, moving away from simply using the lowest bid as a reference point and requiring transparency from the lowest bidders regarding their pricing [3][4] - A recent meeting by the National Medical Insurance Administration focused on supporting innovation in drugs and medical devices, discussing new pricing policies and mechanisms to encourage the entry of high-level technological innovations into clinical applications [4] - CITIC Securities reports that the government has introduced multiple policies since 2025 to optimize drug procurement and support innovative drugs, indicating a favorable policy environment for the pharmaceutical industry [5]

Core Viewpoint - The article discusses the achievements and future plans of China's medical insurance system during the "14th Five-Year Plan" period, highlighting improvements in coverage, fund management, and the introduction of long-term care insurance [1][3]. Group 1: Medical Insurance Coverage - The national basic medical insurance coverage rate remains stable at around 95%, with a cumulative expenditure of 12.13 trillion yuan, averaging an annual growth rate of 9.1% [1][3]. - By 2024, the number of people covered by basic medical insurance is expected to reach 1.327 billion, with long-term care insurance coverage at 190 million [1][3]. - The direct settlement rate for cross-provincial medical expenses exceeds 90%, and the national medical insurance drug list has been unified, totaling 3,159 types of drugs [1][3]. Group 2: Long-Term Care Insurance - The long-term care insurance system is expected to be implemented nationwide soon, as the current pilot programs have shown positive results [4][7]. - As of June 2025, 253 million people are participating in maternity insurance, with cumulative expenditures of 438.3 billion yuan, benefiting 96.14 million people [6]. - The long-term care insurance aims to alleviate the financial burden of daily care for elderly individuals who have lost their ability to care for themselves, addressing the increasing demand for elderly care services [6][7]. Group 3: Fund Management and Regulation - The medical insurance fund is under increasing pressure, and the focus will be on ensuring fund safety and risk assessment during the "15th Five-Year Plan" period [4][8]. - The reform of payment methods has transitioned from a "post-payment" to a "pre-payment" system, promoting efficiency in medical institutions and reducing patient out-of-pocket expenses by approximately 5% year-on-year [9][10]. - The National Medical Insurance Administration has intensified efforts to combat fraud and misuse of medical insurance funds, recovering 16.13 billion yuan in the first half of the year through inspections of 335,000 medical institutions [10][11]. Group 4: Drug Price Governance - The article emphasizes the importance of drug price governance, with the government supporting market-driven pricing while also maintaining oversight to prevent price manipulation [12][13]. - Since 2018, the government has conducted 10 rounds of centralized drug procurement, covering 435 types of drugs, which has helped lower drug prices and improve accessibility [13][14]. - The National Medical Insurance Administration is committed to ensuring fair pricing practices and encourages public reporting of unusually high drug prices [14].

7月24日，国家医疗保障局副局长施子海在国新办发布会上表示，近期第11批药品集采工作已经启动， 国家医保局研究优化了具体的采购规则。在中选规则方面，优化了价差计算的"锚点"，不再以简单的最 低价作为参考，同时报价最低企业要公开说明报价的合理性，并承诺不低于成本报价。 施子海指出，集采过程中，国家医保局将按照国务院常务会议研究通过的优化集采措施，坚持"稳临 床、保质量、防围标、反内卷"的原则。 "过去简单以最低价作为药品集采参考，让企业陷入价格战漩涡。为了中标，企业拼命压低价格，甚至 不惜低于成本报价，这不仅压缩了利润空间，还导致企业无暇顾及研发创新。"国研新经济研究院创始 院长朱克力向证券时报记者表示，国家医保局相关举措，能有效遏制恶性低价竞争。企业不能再盲目压 价，而是要综合考虑成本、质量等因素合理报价，将促使企业把精力从价格战转移到提升药品质量和研 发创新上。从医药行业整体看，这有利于形成良性竞争环境，让真正有实力、有创新能力的企业脱颖而 出，推动整个行业向高质量发展迈进。 在质量保证方面，要求投标药品的生产线两年内不存在违反药品生产质量管理规范的情形，药监部门对 集采中选企业检查和产品抽检两个"全覆盖" ...

Group 1 - The National Medical Insurance Administration (NMIA) has initiated the 11th batch of drug procurement, focusing on optimizing procurement rules while ensuring clinical stability, quality assurance, and preventing price collusion [1][2] - Since 2018, the NMIA has conducted ten batches of centralized procurement covering 435 drug varieties, which has effectively reduced drug prices and improved accessibility for the public [1][2] - The 11th batch aims to include 55 drug varieties across various therapeutic areas, maintaining the principle of excluding new drugs from procurement and aligning with the medical insurance catalog negotiations [2] Group 2 - The NMIA is advancing payment reform during the 14th Five-Year Plan, transitioning from a retrospective payment system to a prospective one, and from project-based payments to disease-based payments [3] - By 2024, the basic medical insurance fund expenditure is projected to reach 2.98 trillion yuan, with a 5% decrease in patient out-of-pocket expenses year-on-year [3] - The NMIA is also enhancing the payment reform by developing version 2.0 of the disease-based payment scheme and establishing supporting mechanisms to promote medical technology innovation [3]

Core Viewpoint - The recent adjustments in China's drug procurement policies mark a shift towards a "value-oriented" approach, moving away from a simple focus on the lowest price, which is expected to foster a healthier development of the pharmaceutical industry [1][3][5]. Group 1: Policy Changes - The 11th batch of centralized procurement has been initiated, with the National Medical Insurance Administration optimizing the rules, particularly in the calculation of price differences, no longer solely relying on the lowest bid as a reference [1][4]. - The new rules require companies to justify their lowest bids and ensure they do not fall below cost, aiming to prevent irrational competition and promote quality over price [2][3]. Group 2: Market Reactions - Following the announcement of the procurement policy adjustments, the capital market responded positively, with many generic drug companies seeing significant stock price increases, with some companies like Yipinhong rising nearly 40% since July 15 [4][5]. - Analysts believe that the new measures will provide companies with more profit margins, reducing the pressure to bid at a loss, which previously compromised product quality [4][5]. Group 3: Industry Impact - The optimization of procurement rules is expected to benefit companies with strong R&D capabilities and strict quality control, promoting structural optimization and high-quality development within the pharmaceutical industry [3][6]. - Some companies are already adapting to the new environment, with reports of increased R&D investments and a shift towards innovative drug development, indicating a positive long-term outlook for the industry [3][7]. Group 4: Historical Context and Future Outlook - Since 2018, ten batches of centralized procurement have been conducted, covering 435 types of drugs, resulting in significant savings for the medical insurance fund, estimated at around 440 billion yuan [6]. - The scope of centralized procurement is expanding to include various drug categories and medical devices, with expectations for continued acceleration in the future [6][7].

Group 1 - The National Healthcare Security Administration announced that drug procurement will no longer simply reference the lowest bid, indicating a shift in policy that could benefit companies with strong quality systems and cost advantages [1] - The recent announcement led to a significant increase in Hong Kong's biopharmaceutical stocks, particularly in the vaccine sector, with notable gains for companies such as Ai Mei Vaccine (+13.5%) and CanSino Biologics (+9.03%) [1] - The 11th batch of centralized procurement has been initiated, with new rules optimizing the calculation of price differences and requiring transparency from the lowest bidders regarding the rationality of their pricing [1] Group 2 - The vaccine sector has shown remarkable performance due to multiple favorable factors, including a warning from the World Health Organization regarding mosquito-borne diseases, which has boosted market sentiment [2] - Ai Mei Vaccine has successfully commercialized eight vaccines, including leading products like rabies and hepatitis B vaccines, and has a robust pipeline of 21 vaccines in development, with three key products nearing market launch [2] - The vaccine sector is seen as having significant potential for valuation recovery, as many companies' pipeline values have not yet been fully reflected in their market valuations [2]

近期第十一批集采工作已经启动。 国务院新闻办公室7月24日上午举行"高质量完成'十四五'规划"系列主题新闻发布会，请国家医疗保障局局 长章轲介绍"十四五"时期深化医保改革，服务经济社会发展有关情况，并答记者问。 要点如下： 全国基本医保参保率稳定在95%左右 章轲在新闻发布会上介绍，"十四五"期间，全国基本医保参保率稳定在95%左右，2024年度全国基本医保 参保人数达13.27亿人。 "十四五"以来累计402种药品进入目录 章轲在新闻发布会上介绍，"十四五"以来累计402种药品进入目录。国家医保药品目录实现全国统一，目 录内药品总数达到3159种。 十四五以来医保基金累计支出12.13万亿元，年均增速9.1% 章轲在新闻发布会上介绍，全国跨省联网定点医药机构达64.4万家，四年多来全国跨省异地就医直接结算 惠及5.6亿人次，累计减少参保群众垫资5900亿元。 全国超9600万人次享受生育保险待遇 章轲在新闻发布会上介绍，截至2025年6月，2.53亿人参加生育保险，基金累计支出4383亿元，享受待遇 9614.32万人次。31个省份和新疆生产建设兵团都将辅助生殖项目纳入医保报销。 2021年至2024年累计 ...