Core Viewpoint - The innovation drug sector has seen a continuous rise in popularity this year, with various indices related to innovation drugs in both Hong Kong and A-shares showing strong performance [1] Index Comparison - The Hang Seng Hong Kong Stock Connect Innovation Drug Index focuses on Hong Kong stocks related to innovation drug research, development, and production, while the CSI Innovation Drug Industry Index targets A-share companies involved in innovation drug R&D, selecting up to 50 representative stocks [2] - The Hang Seng index excludes contract research organizations (CROs) and selects stocks based on their relevance to innovation drug business, while the CSI index does not exclude CROs and selects the largest 50 stocks by market capitalization [2] Industry Distribution - The CSI Innovation Drug Industry Index has a higher weight in chemical preparations (46.6%) and medical R&D outsourcing (21.3%), while the Hang Seng index has a greater focus on chemical preparations (48.9%) and other biological products (41.1%) [5] - The Hang Seng index excludes medical outsourcing companies, leading to a different industry distribution compared to the CSI index, which includes this segment [5] Component Stock Concentration - The Hang Seng index has a higher concentration of component stocks, with the top ten stocks accounting for approximately 75% of the index, while the CSI index's top ten stocks account for less than 50% [9] - Major stocks in the CSI index include WuXi AppTec (13.09% weight) and Hengrui Medicine (10.19% weight), while the Hang Seng index features CSPC Pharmaceutical (10.75% weight) and China National Pharmaceutical (10.31% weight) [11] Summary - Both indices focus on the innovation drug industry but differ in their compilation rules, industry distribution, and component stocks, which investors should consider based on their investment goals and risk tolerance [12]

Core Viewpoint - The SHS Innovation Drug Index has shown significant growth, reflecting the performance of listed companies involved in innovative drug research and production in both mainland China and Hong Kong [1]. Group 1: Index Performance - The SHS Innovation Drug Index increased by 4.03%, reaching 2393.56 points, with a trading volume of 54.435 billion [1]. - Over the past month, the index has risen by 11.98%, and over the last three months, it has increased by 35.45%. Year-to-date, the index has surged by 47.88% [1]. Group 2: Index Composition and Adjustments - The index is composed of up to 50 representative securities selected from mainland and Hong Kong markets, focusing on companies engaged in innovative drug development and production [1]. - The index is adjusted semi-annually, with changes implemented on the next trading day following the second Friday of June and December each year. Weight factors are generally fixed until the next adjustment [1]. - In special circumstances, the index may undergo temporary adjustments, such as when a sample company is delisted or undergoes mergers, acquisitions, or splits [1].

Group 1 - The innovative drug sector has experienced adjustments after a strong rally, with significant capital inflow into ETFs indicating renewed investor interest [1][2] - Since the beginning of the adjustment on July 30, the net subscription amount for innovative drug-themed ETFs has exceeded 10 billion yuan, reaching 100.09 billion yuan by August 11 [2] - Major ETFs such as Guangfa CSI Hong Kong Innovative Drug ETF and Huatai-PineBridge CSI Hong Kong Innovative Drug ETF have seen substantial net subscriptions, indicating strong demand [2][4] Group 2 - Long-term funds have been actively increasing their positions in innovative drug-themed ETFs, with notable performances reported, such as the Huatai-PineBridge Hong Kong Advantage Selected Mixed Fund achieving over 130% returns this year [4][6] - The innovative drug sector is expected to see further differentiation, with a focus on companies with strong fundamentals as the market evolves [6][7] - The domestic policy environment is improving, enhancing the market potential for innovative drugs, and the global expansion of these drugs is accelerating, providing significant growth opportunities [7][8] Group 3 - The valuation logic for the innovative drug sector differs from traditional industries, relying more on future product sales peaks and cash flow discount models, suggesting potential for further valuation increases as global development progresses [8] - The Chinese innovative drug industry is currently experiencing explosive growth, transitioning from a follower to a leader in the global market, with a significant increase in approved drugs and overseas licensing transactions [7][8]

Group 1 - The Hang Seng Hong Kong Stock Connect Innovative Drug Index has revised its compilation scheme, officially effective from August 11, focusing solely on core innovative drug companies by excluding CXO companies [1] - CXO companies provide outsourcing services for pharmaceutical and biotech firms and do not directly acquire core intellectual property of innovative drugs, thus not bearing the risks associated with new drug development [1] - The exclusion of 5 CXO companies, which previously accounted for approximately 20% of the index's weight and underperformed compared to the overall index, has led to improved performance metrics for the revised index, including an annualized return exceeding 47% since its publication [1] Group 2 - China's innovative drug industry has made significant progress, with reduced innovation costs and improved R&D efficiency, leading to a pipeline that ranks second globally, attracting multinational pharmaceutical companies to increase their procurement of innovative drug patents [2] - The Hang Seng Hong Kong Stock Connect Innovative Drug Index has seen a cumulative increase of about 100% year-to-date as of August 5, highlighting the strong performance of the Hong Kong pharmaceutical sector [2] - The Hang Seng Innovative Drug ETF is currently the only product tracking the revised index, with its latest scale surpassing 1 billion yuan, enabling investors to better allocate resources towards leading innovative drug companies in Hong Kong [2]

回顾这一轮创新药板块的行情，廖庆阳将今年2月至5月划分为第一波主升浪，5月以来划分为第二波主 升浪。在他看来，当前第二波主升浪行情仍在持续。 "第一波行情主要源于医保政策的推动，创新药不仅可以由医保支付，商业保险也逐步覆盖。在此过程 中，一些医药企业逐步有大额的BD项目出现，创新药在AI及机器人之后承接了市场的热点切换。而支 撑起第二轮行情的因素，一是在以ASCO年会为代表的全球创新药学术会议上，中国大量优秀的创新药 产品凭借出色的临床验证成果，获得了全球投资者的高度关注；二是全球大型跨国制药企业对国内创新 药产品进行'扫货式'抢购，大型BD交易浮出水面，正式开启了这一轮国内创新药资产的价值重估。"廖 庆阳总结道。 在廖庆阳看来，BD交易爆发的原因，一方面是全球大型跨国制药公司专利药进入了快速迭代的"悬崖 期"，另一方面是肿瘤等重大疾病的治疗方式正经历重大变革。在这样的迭代周期中，跨国公司发现， 中国的创新药企业经过多年蛰伏，已经能生产出疗效显著的创新药产品，并且成本要远低于欧美的大型 生物技术公司，工程师红利的释放使得中国创新药管线迅速扩围。因此，中国创新药企业开始在资本市 场上得到广泛认可。 差异化挖掘黑 ...

Core Viewpoint - The SHS Innovation Drug Index has shown significant growth, with a 21.77% increase over the past month, 33.51% over the past three months, and 50.42% year-to-date, indicating a strong performance in the innovative drug sector in both mainland China and Hong Kong [1]. Group 1 - The SHS Innovation Drug Index opened lower but closed higher, rising by 4.05% to 2435.18 points, with a trading volume of 68.919 billion yuan [1]. - The index is composed of up to 50 representative securities from the mainland and Hong Kong markets, focusing on companies involved in innovative drug research and production [1]. - The index was established on December 31, 2014, with a base point of 1000.0 [1]. Group 2 - The index samples are adjusted semi-annually, with adjustments occurring on the next trading day after the second Friday of June and December each year [1]. - Weight factors are generally fixed until the next scheduled adjustment, with special circumstances allowing for temporary adjustments [1]. - The index will be adjusted if a sample company is delisted or if there are significant corporate changes such as mergers or acquisitions [1]. Group 3 - Public funds tracking the SHS Innovation Drug Index include various ETFs and fund products from institutions like Guotai, Xizang Dongcai, and Fuguo [2].

Core Viewpoint - The report highlights the strong performance of the Dongwu Medical Services Stock A fund, driven by the innovation drug sector, with a significant net value growth rate and positive returns over various time frames [2][3]. Fund Performance - In Q2 2025, the fund reported a profit of 8.0949 million yuan, with a weighted average profit per fund share of 0.106 yuan [2]. - The fund's net value growth rate for the reporting period was 18.12%, and as of the end of Q2, the fund size was 52.522 million yuan [2][15]. - As of July 18, the fund's unit net value was 0.822 yuan, with a one-year cumulative net value growth rate of 75.56%, ranking it 8th out of 53 comparable funds [2][3]. Investment Strategy - The fund focuses on long-term investments in pharmaceutical and medical stocks, with a portfolio primarily composed of innovative drugs [2][3]. - The fund manager noted that despite market volatility due to international trade impacts, the innovative drug sector quickly rebounded, reflecting confidence in the industry's trends [2]. Comparative Performance - The fund's three-month net value growth rate was 47.93%, ranking 5th out of 54 comparable funds, while the six-month growth rate was 69.65%, ranking 8th out of 54 [3]. - Over the past three years, the fund's Sharpe ratio was -0.0279, ranking 21st out of 46 comparable funds [8]. - The maximum drawdown over the past three years was 51.61%, with the largest single-quarter drawdown occurring in Q3 2022 at 24.3% [10]. Portfolio Composition - As of Q2 2025, the fund's top ten holdings included companies such as Innovent Biologics, CanSino Biologics, and 3SBio, indicating a high concentration in its stock holdings [17]. - The average stock position over the past three years was 85.43%, with a peak of 91.31% at the end of Q3 2022 and a low of 78.09% at the end of Q1 2023 [13].

Group 1 - The fund is named "Innovative Drug ETF Hong Kong-Shanghai-Shenzhen" and is managed by Tibet Dongcai Fund Management Co., Ltd. [2] - The fund aims to closely track the performance of the underlying index, minimizing tracking deviation and error [2][10]. - As of the end of the reporting period on June 30, 2025, the total fund shares amounted to 236,603,238 [2][14]. Group 2 - The fund's investment strategy primarily employs a full replication method, constructing the investment portfolio based on the composition and weight of the underlying index [2][10]. - The fund's performance benchmark is the China Securities Index for the innovative drug industry, which reflects the overall performance of listed companies in this sector [4][10]. - The fund's net asset value growth rate for the reporting period was 8.60%, outperforming the benchmark return of 7.86% [10]. Group 3 - The fund's asset allocation as of the reporting period includes 97.67% in stocks, with no holdings in bonds or asset-backed securities [11]. - The healthcare sector represents 41.91% of the fund's net asset value, indicating a significant focus on this industry [12][13]. - The fund's total subscription during the reporting period was 80,000,000 shares, while total redemptions were 76,000,000 shares [14].

Group 1 - The Hong Kong pharmaceutical sector is experiencing positive momentum, with notable stock increases for companies such as Lijun Pharmaceutical (up over 13%), Green Leaf Pharmaceutical, and Fosun Pharmaceutical (both up over 8%) [1] - The State Medical Insurance Administration and the National Health Commission have introduced measures to support the high-quality development of innovative drugs, focusing on issues faced by the innovative drug sector and proposing 16 measures across five areas [1] - The measures aim to provide comprehensive support for the entire chain of innovative drug development, including research, market access, hospital usage, and diversified payment methods, emphasizing genuine support for innovation [1] Group 2 - Guoyuan Securities highlights the importance of increasing the commercial insurance innovative drug directory, indicating a strengthened role for commercial insurance in the multi-tiered medical security system, which is a significant step for market access [2] - The ongoing reform of medical insurance payment methods by the National Medical Insurance Administration is expected to create broader opportunities for commercial insurance, enhancing its flexibility and supplementary role in supporting high-priced innovative drugs and medical devices [2] - The aging population in China is driving a rigid growth in demand for pharmaceuticals and healthcare services, particularly among the elderly who face multiple chronic diseases, thus expanding the pharmaceutical market [2] Group 3 - The Chinese pharmaceutical industry has maintained steady growth, demonstrating resilience even during challenging economic conditions, with a notable anti-cyclical consumption pattern [3] - The increasing elderly population is not only raising the demand for basic medications but also creating a need for specialized treatments, rehabilitation care, and health monitoring services, providing ample opportunities for the development of niche markets within the pharmaceutical sector [3] - The demand growth driven by demographic changes is characterized by long-term stability, serving as a core driver for the sustained development of the pharmaceutical industry [3]

Group 1 - The report outlines a grid trading strategy, which is essentially a high buy low sell trading approach that capitalizes on price fluctuations without predicting market trends, making it suitable for volatile markets [3][13] - Characteristics of suitable grid trading targets include being exchange-traded, having stable long-term trends, low transaction costs, good liquidity, and high volatility, with equity ETFs being identified as appropriate candidates [3][13] Group 2 - The report highlights key ETFs for grid trading strategies, including the Medical ETF (512170.SH), which benefits from the aging global population and supportive policies for innovative drug development in China [3][14] - The Artificial Intelligence ETF (159819.SZ) is noted for its growth potential due to government initiatives promoting AI technology across various sectors, with 433 domestic large models registered as of June 30, 2025 [4][17] - The Robotics ETF (159530.SZ) is positioned as a strategic core area for China's technological innovation and high-end manufacturing, with significant government support and recent projects indicating a shift towards commercialization [5][19] - The Germany ETF (159561.SZ) tracks the DAX index and is expected to benefit from Germany's fiscal expansion plans, which include borrowing approximately €500 billion for defense and €300 billion for infrastructure, representing about 20% of GDP [7][21]