Core Viewpoint - The successful IPO of InnoCare Pharma (映恩生物) marks the largest scale IPO in the Hong Kong 18A biotech sector since 2022, raising a total of $211 million, significantly exceeding initial plans, indicating strong market confidence in its innovation capabilities [1] Group 1: IPO Details - The IPO achieved a threefold increase in valuation, making it the project with the largest valuation increase among Hong Kong 18A biotech companies that raised over $50 million [1] - The international placement was oversubscribed by 14.9 times, the highest subscription multiple for 18A biotech since 2022 [1] - The company attracted 15 top international long-term funds and leading domestic public funds, with cornerstone investors agreeing to subscribe for a total of $65 million (approximately HKD 505 million) under certain conditions [1] Group 2: Company Overview - InnoCare Pharma, operational since 2020, is a global leader in the field of antibody-drug conjugates (ADC), conducting seven global clinical trials across 230 clinical trial centers in 17 countries, enrolling over 2,000 patients, with 50% of patients from overseas [2] - The company has two core products in development: DB-1303/BNT323 targeting HER2 cancers and DB-1311/BNT324 targeting B7-H3 cancers [2] Group 3: Regulatory Approvals and Collaborations - Five clinical-stage assets have received Investigational New Drug (IND) approvals from the FDA and the National Medical Products Administration of China [3] - The company's innovative ADC assets have attracted leading global biopharmaceutical companies, establishing several global partnerships with a total transaction value exceeding $6 billion [3] - The "platform technology output + global clinical collaboration" model accelerates the R&D process and reduces financial pressure, generating approximately $500 million in upfront revenue as of the end of 2024 [3] Group 4: Financial Performance and Market Recognition - The company is expected to achieve revenues of approximately RMB 1.787 billion and RMB 1.941 billion for 2023 and 2024, respectively, benefiting from the international expansion of ADCs [3] - The successful issuance of shares signifies international capital's recognition of the global capabilities of Chinese innovative pharmaceutical companies, providing a new path for 18A companies to break through valuation bottlenecks [4] - As the ADC sector continues to heat up, leading companies with platform technology and clinical differentiation advantages are likely to see further value reassessment [4]

智通财经APP讯，映恩生物-B(09606)于2025年4月7日至4月10日招股，公司拟全球发售1507.16万股股 份，其中，香港发售占10%，国际发售占90%，另有超额配股权15%。每股发售价94.6-103.2港元，每手 100股，预期股份将于2025年4月15日(星期二)开始在联交所买卖。 我们于2019年注册成立，是全球抗体偶联药物(ADC)领域的关键领跑者，致力于为癌症和自身免疫性疾 病等患者研发ADC创新药物。我们拥有自主研发的两款核心产品，即DB-1303/BNT323(一款靶向癌症 (包括子宫内膜癌(EC)及乳腺癌(BC))的HER2 ADC候选药物)及DB-1311/BNT324(一款靶向癌症(包括小细 胞肺癌(SCLC)、去势抵抗性前列腺癌(CRPC)、食管鳞状细胞癌(ESCC)及头颈部鳞状细胞癌(HNSCC))的 B7-H3 ADC候选药物)。 除核心产品外，我们还自主研发了：五款其他临床阶段ADC(即DB-1310、DB-1305/BNT325、DB- 1312/BGC9074、DB-1419及DB-2304)，在广泛适应症中具有潜力，根据Frost & Sullivan，就总体或主 ...