该行表示，近期，医药板块有所回调(MSCI中国医疗指数10月至今回调14%)。该行认为，近期的回调主 要是估值与预期的消化与再平衡，这将为后续投资创造更优的布局窗口。展望2026年，创新药出海趋势 将长期延续，该行将聚焦在已出海管线的临床进展与数据兑现此一核心催化。政策端方面，《生物安全 法案》虽已签署生效，但预期该法案对中国CXO企业实质经营影响有限。 智通财经APP获悉，招银国际发布研报称，MSCI中国医疗指数2025年初至今累计上涨51.9%，跑赢 MSCI中国指数24.3%。该行表示，布局想法更偏稳健，关注低估值个股机会。推荐买进三生制药 (01530)、固生堂(02273)、药明合联(02268)、中国生物制药(01177)，评级均为"买入"。 ...

近一年，QDII产品的业绩呈现明显分化。据统计，截至12月17日，排名首位的汇添富香港优势精选混 合A净值涨幅为111%，领先排名末位的产品124.6个百分点。受益于港股创新药整体涨幅较大，相关产 品在QDII基金业绩榜上排名居前。相较之下，沙特主题ETF和原油类产品近一年则普遍表现疲软，位列 排行榜尾端。 Choice数据显示，截至12月17日，QDII基金近一年净值平均上涨20.9%。其中，汇添富香港优势精选混 合A以111%的净值涨幅排名首位，紧随其后的是创金合信全球医药生物股票发起A、广发中证香港创新 药，净值涨幅分别为86.54%、74.14%。此外，易方达全球医药行业混合、南方港股医药行业混合发起 A、华夏恒生生物科技ETF等产品近一年净值涨幅均超过60%。 从QDII基金业绩排行榜来看，前十位主要是港股基金，其中不少产品重仓了港股医药板块。以汇添富 香港优势精选混合A为例，截至三季度末，基金前五大重仓股分别是映恩生物-B、科伦博泰生物-B、信 达生物、三生制药和康诺亚-B。而易方达全球医药行业混合前五大重仓股分别为复宏汉霖、信达生物、 科伦博泰生物-B、映恩生物-B和乐普生物-B。 （文章来源： ...

"医药行业最困难的时刻可能已经过去了。" 融通基金基金经理万民远的一句感慨道出了众多医药基金经理、基民和股民多年持仓的坚守与转折。随 着港股创新药的牛市行情仍在持续演进，今年不少基民发现，自己持有亏损多年的医药基金开始赚钱 了。 近期港股创新药板块持续走强，医药股、医药基金投资价值再次引起市场关注。证券时报·券商中国记 者采访国泰基金麻绎文、景顺长城基金金璜、融通基金万民远、金鹰基金欧阳娟、华富基金廖庆阳、诺 安基金唐晨等多位基金经理，围绕市场反弹动因、全年主线逻辑及细分赛道机会展开深度解读。 接受采访的多位基金经理均认为，港股创新药板块的上涨并非短期情绪驱动，而是政策红利、产业升 级、全球化突破等长周期逻辑的集中体现。尽管短期需关注政策落地节奏与外部环境变化，但中国创新 药从"跟跑"到"领跑"的趋势已然确立，在全球产业链中的价值重估进程方兴未艾。对于投资者而言，把 握创新药出海与技术融合主线，兼顾低估值修复与业绩兑现逻辑，或是分享产业升级红利的关键。 医药行业最困难时刻或已过去 Wind数据显示，年初低位以来，恒生医疗保健指数（HSHCI.HI）上涨达到31.89%，远超同期恒生科技 指数和恒生中国企业指数 ...

Industry Rating - The report rates the pharmaceutical industry as "Leading" [1] Core Insights - The report highlights a concentrated trend of domestic innovative drug collaborations and transactions as the year ends, with expectations for value recovery in 2026 [1][4] - The overall market performance shows a decline, with the Hang Seng Index down 0.8% and the Hang Seng Healthcare Index down 4.3% during the week [4][7] - The report emphasizes the importance of stock selection logic returning to fundamentals and valuations, focusing on stocks that are currently undervalued with expected fundamental improvements [4] Valuation Summary - The report provides a detailed valuation overview of various companies, indicating target prices and earnings per share estimates for FY25E and FY26E, along with their respective price-to-earnings ratios [3] - Notable companies with "Buy" ratings include AstraZeneca, BeiGene, and Hansoh Pharmaceutical, with target prices significantly above current trading prices [3] Market Trends - The report notes a slight decrease in domestic institutional holdings through the Hong Kong Stock Connect, while foreign holdings remain stable [33] - The report identifies a trend of increasing positions in leading innovative pharmaceutical companies by domestic investors, particularly in companies like Heng Rui Medicine and Rongchang Bio [36] Investment Insights - The report mentions several significant business development (BD) transactions exceeding $1 billion, indicating a robust pipeline for innovative drugs [4][5] - It recommends focusing on specific segments such as innovative drugs and CXO companies that are expected to benefit from downstream recovery and high market demand [4]

12月18日早盘，A股港股市场弱势震荡，医药资产逆市活跃，彰显防御力。 A股市场上，医疗板块延续较强反弹力度，全市场最大医疗ETF（512170）盘中涨超1%上穿年线！民 营医院、AI医疗相关成份股涨幅居前，美年健康两连板，卫宁健康涨超7%。 制药板块个股涨跌分化，中药龙头片仔癀涨超1%，创新药概念股甘李药业、海思科跌1%，全市场唯一 药ETF（562050）水面附近盘整。 值得一提的是，昨日，医疗ETF（512170）日K呈现"一阳包两阴"形态，技术面释放"多空转换"信号！ 今日如能成功收于年线上方，短期趋势有望反转。资金面上，近期部分资金逢跌吸筹，512170近10日累 计吸金超9300万元。 港股医药今日一枝独秀，截至发稿恒指、恒科指均飘绿，创新药龙头多股上涨，百济神州涨超1%，石 药集团涨超3%，创新药含量100%的港股通创新药ETF（520880）盘中直线拉升翻红！ 近期资金连续押注创新药反弹，截至12月17日，520880连续8日获资金净申购，最新基金份额升至41.76 亿份，继续刷新上市以来最高份额纪录！ | | | 分野 多日 1分 5分 15分 30分 60分 · | | | | | F9 ...

生物医药 2026 年度策略：十年创新，踏出海征程 20251217 摘要 2025 年 CXO 和化学制药板块表现突出，基金持仓集中度提升。诊疗端 需求稳定，医保基金结存率显著回升，控费效果明显。商保创新药目录 发布为医药行业带来新的支付增量。 2025 年前三季度 license out 交易金额达 920 亿美元，同比增长超一 倍，表明国内创新药受到海外认可。港股 IPO 回暖带动一级市场投融资 回升，多家医药企业上市。 2026 年医药行业关注创新，重点关注 IO 双抗和 GLP-1 两大主线。康方 生物 PD-1/VEGF 双抗 AK112 研发进度领先，多个关键临床数据将在明 年更新。 双抗领域备受关注，康方生物 AK112 等产品积极推进出海，并围绕非 小细胞肺癌等适应症开展全球三期临床试验，将成为明年的重要催化剂。 IO 加 ADC 是未来发展方向。科伦博泰 SKB264 在全球开展多项临床三 期试验，与默沙东 Keytruda 联合使用，有望重新定义 IO 加 ADC 治疗 格局。 Q&A 今年（2025 年）医药行业整体表现如何？有哪些重要的边际变化？ 今年（2025 年），医药行业整体估 ...

Core Viewpoint - The launch of the China Drug Price Registration System is expected to accelerate the internationalization of Chinese innovative drugs by providing a global, authoritative, standardized, and transparent market price registration platform [1] Group 1: Overview of the Drug Price Registration System - The China Drug Price Registration System is a national-level price registration platform independent of the medical insurance network, offering services such as price registration, price inquiry, price comparison, and notarization [2][8] - Pharmaceutical companies can autonomously declare and register drug prices based on their development needs, ensuring the authenticity of the submitted information, while the operating unit only processes registration applications without interfering with pricing [2][8] Group 2: Impact on Chinese Innovative Drugs - The system aims to address the pricing challenges faced by Chinese innovative drugs in international markets, which have been hindered by reliance on medical insurance negotiation prices that may undervalue these products [3][9] - The establishment of a "one drug, one file" database will provide authoritative pricing references for companies, facilitating the construction of a consistent pricing system for domestic and international markets [3][9] Group 3: Four Major Impacts on Domestic Innovative Drugs - Accelerating Internationalization: In the first three quarters of 2025, Chinese pharmaceutical companies completed over 103 overseas licensing transactions, with a total transaction value exceeding $92 billion, highlighting the increasing reference value of China's terminal prices [6][12] - Enhancing Commercial Certainty: The system operates independently from provincial medical procurement platforms, allowing companies to declare prices applicable to various healthcare settings, including private hospitals and self-funded medical services [6][13] - Attracting Multinational Pharmaceutical Companies: The system not only supports the international expansion of Chinese innovative drugs but also attracts high-quality foreign drugs to the Chinese market, enhancing competition [6][13] - Promoting Healthy Competition and Innovation Incentives: The market identity associated with the declared prices reflects the clinical value of innovative drugs, enabling companies to achieve higher returns in non-medical insurance markets, thus fostering a positive cycle of research and development [6][13]

创新药阶段调整期，资金加速"抄底"核心资产！ 以创新药含量100%的港股通创新药ETF（520880）为例，其标的指数自9月上旬开始回调，截至12月16 日收盘回撤逾22%，港股通创新药ETF（520880）近日迭创近5个月新低。 随着场内价格持续走低，港股通创新药ETF（520880）份额逆向走高，反映部分资金看好板块当前配置 性价比。截至12月16日，520880连续7日获资金净申购，最新基金份额升至41.72亿份，续创上市以来新 高！ 就港股创新药板块调整原因，分析指出，12月港股市场整体承压，创新药等前期涨幅大、估值弹性高的 板块更易成为资金出逃对象。同时，市场预期日本央行将在12月加息，外部流动性收紧预期或加剧板块 波动。此外，年底市场风险偏好下降、机构资金获利了结调仓等也有一定影响。 但从投资逻辑来看，中长期维度，驱动中国创新药发展的底层逻辑"出海加速、技术升级和商业化兑 现"并未改变。有机构表示，预计行业大会（临床数据进展，1月JPM大会）、重磅BD交易、新技术突 破等仍将持续为行业带来正面催化，时点上或可重点关注2026年一季度。 把握港股创新药低吸窗口期，认准同类最大港股通创新药ETF（52 ...

12月16日，港股通创新药加速筑底，核心标的港股通创新药ETF（520880）盘中一度下探3%，场内价 格收跌1.91%再创近5个月新低，逼近上市初价格水平。所覆盖的37家创新药研发类上市公司29跌8涨， 复星医药跌5.81%居首，权重股石药集团、三生制药跌逾2%。 12月以来的12个交易日里，港股通创新药ETF（520880）仅有2日收涨，"跌跌不休"所为何？分析指 出，12月港股市场整体承压，创新药等前期涨幅大、估值弹性高的板块更易成为资金出逃对象。同时， 市场预期日本央行将在12月加息，外部流动性收紧预期或加剧板块波动。此外，年底市场风险偏好下 降、机构资金获利了结调仓等也有一定影响。 从资金动向来看，近期逢跌分批吸筹动作明显。昨日板块大幅调整，港股通创新药ETF（520880）单日 获超7500万元净申购，至此520880已连续6日吸金合计超2亿元，份额升至41.48亿份新高！今日场内延 续宽幅溢价，显示买盘资金仍强势。 从配置性价比角度，港股通创新药ETF（520880）标的指数自9月上旬开始进入阶段调整期，截至今日 收盘回撤幅度超过22%，调整较为充分，并释放出弹性空间。 港股通创新药调整何时休？ ...

Core Insights - The pharmaceutical industry is experiencing a surge in innovative products, with clear domestic demand and significant potential for international expansion [4][14][25] - Investment opportunities are concentrated in innovative drugs and their supply chains, with a notable performance from CRO/CMO and chemical pharmaceuticals [9][15][17] - The report emphasizes the importance of innovation as the primary solution to industry challenges, driven by stable demand and supportive policies [26][32][41] Industry Overview - The pharmaceutical sector has faced revenue declines, with a 0.9% year-on-year decrease in revenue for the first three quarters of 2025, and net profit down by 2.2% [15][16] - The innovative drug sector has outperformed, with CRO/CMO and chemical pharmaceuticals showing net profit growth of 31.0% and 16.6% respectively [17][18] - The overall market is characterized by low fund holdings and historical valuation bottoms, indicating high investment value [20][25] Demand and Payment Dynamics - The demand for healthcare services is steadily increasing, with a projected 5% growth in total medical visits and hospital admissions in 2024 [26][28] - The aging population is expected to drive long-term demand, with 220 million people aged 65 and above by 2050 [28][30] - The medical insurance fund's income growth has outpaced expenditure growth, leading to a significant increase in fund reserves [32][36] Financing and Market Trends - The IPO market for healthcare has rebounded, with 28 IPOs in the first three quarters of 2025, a 100% increase from the previous year [42][43] - License-out transactions have surged, with transaction numbers increasing by 41% and total amounts reaching $92 billion, indicating a robust market for innovative drug licensing [48][50] - The number of IND applications and new clinical trials for innovative drugs has been steadily increasing, with a notable rise in NDA approvals [53][57] Technological Advancements - The report highlights the emergence of new technologies such as ADC and small nucleic acids, with domestic companies leading in these areas [60] - The focus on dual antibodies and GLP-1 drugs is expected to drive significant growth, with multiple development directions emerging [9][60] - The report notes that domestic companies are increasingly recognized for their innovative capabilities, particularly in the ADC space [60]