Revenue Highlights - In FY2025, the company's operating revenue reached 30.6 billion yuan, representing a year-on-year growth of 13%, primarily driven by the rapid growth of its pharmaceutical platform business [1] - The self-operated pharmaceutical revenue was 26.1 billion yuan, up 10% year-on-year, mainly due to the continuous enrichment of B2C retail product SKUs, which increased by 33.6% to 1.23 million, along with growth in medical devices driven by national subsidies [1] - E-commerce platform service revenue amounted to 3.6 billion yuan, a year-on-year increase of 54%, benefiting from the injection of health category advertising business, with the number of platform merchants growing by 35% to 48,300 and SKUs increasing by 91% to 133 million [1] - Revenue from healthcare and digital services was 890 million yuan, showing a year-on-year decline of 8% [1] Profitability Insights - The adjusted net profit for FY2025 was 1.95 billion yuan, reflecting a year-on-year increase of 36%, with an adjusted net profit margin of 6.37%, up 1 percentage point [2] - Gross margin improved to 24.3%, an increase of 2.5 percentage points, primarily driven by the consolidation of higher-margin advertising business [2] - The fulfillment expense ratio was 8.4%, down 0.5 percentage points, with fulfillment expenses accounting for 9.8% of self-operated business revenue, a decrease of 0.4 percentage points, mainly due to improved operational efficiency in warehousing, logistics, and customer service [2] - The sales expense ratio was 7.4%, up 0.8 percentage points, while the management expense ratio remained stable at 1.3% [2] - The R&D expense ratio was 2.4%, down 0.2 percentage points, attributed to cost control and optimized R&D strategies [2] Future Outlook - The company is actively exploring AI in healthcare, enhancing operational efficiency across various scenarios such as optimizing pharmaceutical search models, smart supply chains for pharmacies, intelligent product operations, and smart customer service [2] - The company aims to empower consumers with an AI-driven product search engine and plans to develop more AI knowledge platform products for doctors, facilitating medical knowledge exchange [2] - Revenue projections for FY2026 and FY2027 are estimated at 33.5 billion yuan and 36.4 billion yuan, respectively, with adjusted net profits of 2.3 billion yuan and 2.8 billion yuan [3] - The company anticipates FY2028 revenue to reach 39.4 billion yuan, with an adjusted net profit of 3.2 billion yuan, currently trading at a FY2025 PE ratio of 31x [3]

Investment Rating - The investment rating for the company is "Outperform the Market" [7] Core Views - The company's revenue for FY2025 reached 30.6 billion yuan, representing a year-on-year growth of 13%, primarily driven by the rapid growth of its pharmaceutical platform business [10][11] - The adjusted net profit for FY2025 was 1.95 billion yuan, an increase of 36% year-on-year, with an adjusted net profit margin of 6.37% [11] - The company is actively exploring AI in healthcare to enhance operational efficiency across various scenarios, including AI-driven product search engines and knowledge platforms for medical professionals [11] Revenue Summary - The company's pharmaceutical self-operated revenue was 26.1 billion yuan, up 10% year-on-year, supported by a 33.6% increase in the number of self-operated B2C retail SKUs to 1.23 million [10] - E-commerce platform service revenue was 3.6 billion yuan, a significant increase of 54%, driven by the health category advertising business, with the number of platform merchants growing by 35% to 48,300 [10] - Revenue from healthcare and digital services declined by 8% to 890 million yuan [10] Profit Summary - The adjusted net profit margin improved by 1 percentage point year-on-year, while the gross margin increased by 2.5 percentage points to 24.3% [11] - The fulfillment expense ratio decreased by 0.5 percentage points to 8.4%, indicating improved operational efficiency in warehousing, logistics, and customer service [11] - The company has potential for further optimization in sales and fulfillment expense ratios, suggesting continued improvement in profitability [11] Financial Forecast - Revenue projections for FY2026 and FY2027 are estimated at 33.5 billion yuan and 36.4 billion yuan, respectively, with adjusted net profits of 2.3 billion yuan and 2.8 billion yuan [3][18] - The forecast for FY2028 includes revenue of 39.4 billion yuan and an adjusted net profit of 3.2 billion yuan [3][18]

Group 1 - The innovative drug concept is gaining strength, with the Shanghai Stock Exchange Sci-Tech Innovation Board Biomedicine Index rising by 0.10% as of the report time, and stocks like Sanofi and others experiencing significant gains [1] - The Sci-Tech Innovation Medicine Index ETF (588700) is closely tracking the Biomedicine Index, showing a 0.20% increase and an active trading volume exceeding 15 million yuan, with a turnover rate of over 5.7% [1] - The Biomedicine Index reflects the overall performance of 50 major listed companies in the biomedicine sector on the Sci-Tech Innovation Board, covering various fields such as biomedicine, biomedical engineering, and biopharmaceuticals [1] Group 2 - Industry analysts predict a recovery in demand by 2025, with expectations of improvement in the consumption medical sector, including medical services and traditional Chinese medicine OTC products [2] - The medical device sector is also anticipated to see improvements by 2025, alongside the emergence of AI in healthcare, which is expected to bring significant changes to the pharmaceutical industry [2] - The pharmaceutical sector is believed to have completed the transition between old and new growth drivers, with enhanced capabilities for innovation and international expansion [2]

Group 1 - The high payment capacity of the European and American markets, along with the premium space for innovative drugs, drives the export of domestic innovative drugs [1] - For example, the pricing of Zepzelca in the US is approximately 63,000 yuan per bottle, while the domestic medical insurance price is only 1,912 yuan per bottle, showing a price difference of over 30 times [1] - In Q1 2025, Zepzelca's sales in the US reached 563 million USD, a year-on-year increase of 60%, confirming the business logic of entering developed markets [1] Group 2 - The Hong Kong stock market's innovative drug sector continues to digest valuations, with the price-to-earnings ratio of the Hong Kong innovative drug index dropping from 64 times on February 21 to 25 times on May 22 [1] - The current layout offers significant cost-effectiveness, as the index's valuation has halved in less than two months [1] - On May 22, the Hong Kong innovative drug sector saw a quick rebound after an initial drop, with several stocks like King’s Glory Biotechnology rising over 5% [1] Group 3 - The Hong Kong innovative drug ETF (159567) has seen a net inflow of 250 million yuan over the past 10 trading days, indicating high market enthusiasm [1] - The ETF tracks the National Index of Hong Kong Innovative Drugs, with 90% of its weight in innovative drug companies, the highest among all medical theme indices [1] - The ETF is expected to benefit from trends such as AI-enabled innovative drug research, the export of domestic innovative drugs, and the gradual improvement of commercial health insurance [1] Group 4 - The innovative drug ETF (159992) tracks an index that includes leading companies in the innovative drug industry, benefiting from AI advancements and the export of domestic innovative drugs [2] - The license-out transaction value has surged from 11 billion USD in 2020 to 51.1 billion USD in the first ten months of 2024, reflecting the growing influence of Chinese pharmaceutical companies in the global market [2] - The emergence of the NewCo model enhances financing capabilities and commercial efficiency for biotech companies, while innovative technologies significantly improve drug development efficiency [2] Group 5 - Leading Hong Kong innovative drug companies like BeiGene and Innovent Biologics show steady growth in revenue and net profit, with the overall sector's price-to-earnings and price-to-book ratios at low levels, indicating a high safety margin [2]

在国内强手如林的公募医药基金经理中，宝盈基金的姚艺相对还是一个低调的名字，这位南开大学商学院硕士毕业的医药 基金掌门，目前的任职年限刚满4年；但就是这样一位低调内敛的基金经理，却在今年以来交出了一张优异的成绩单。 来自银河的数据显示，截至5月16日，姚艺所管理的基金年内收益全部飘红，特别是他管理时间最长的宝盈医疗健康沪港深 股票基金，A类过去六个月收益已经达到了21.14%。同时，由他所挂帅的宝盈创新医疗混合发起式基金正在发行中。 问：在医药行业中，普遍认为创新药是目前逻辑最顺的子行业，能否具体解释一下原因所在？ 姚艺：对国内而言，创新药是内需、刚需、必选费品，政策很支持；对海外而言，出海多以BD方式，即专利使用费授权， 后续生产销售、注册归海外大药企，我们仅收首付款、里程碑付款和净销售分成，大概率不受关税影响。美国也不会单方 面限制美企买中国企业产品，否则会降低美制药企业全球竞争力，与美国科技优先政策不符。 | 基金简称 | 过去六个月增长 | 过去一年净值增长率 | 排序 | 过去两年净值增长率 | 排序 | | --- | --- | --- | --- | --- | --- | | | 率(%) | ...

Group 1: Market Performance - The Hong Kong pharmaceutical and biotechnology sector has shown strong performance, with the Hang Seng Healthcare Index ETF (159557) rising 1.9% as of May 21, aiming for a fourth consecutive increase, with a premium rate of 0.23% [1] - Over the three trading days from May 16 to May 20, the Hang Seng Healthcare Index ETF (159557) accumulated a total increase of approximately 6.4% [1] - Notable individual stock performances include Ascentage Pharma-B rising over 10%, and other companies like CanSino Biologics, Innovent Biologics, and 3SBio increasing by over 6% [1] Group 2: Company Developments - 3SBio announced a significant agreement with Pfizer on May 20, granting exclusive rights for the global development, production, and commercialization of its PD-1/VEGF bispecific antibody SSGJ-707, excluding mainland China [2] - The agreement includes an upfront payment of $1.25 billion and potential milestone payments totaling up to $4.8 billion, leading to a total potential transaction value of $6.05 billion, which exceeds 43 billion RMB at current exchange rates [2] - This transaction sets a new record for the highest upfront payment for a domestic innovative drug license-out deal [2] Group 3: Industry Outlook - The innovative drug sector is expected to maintain its growth trajectory, driven by "innovation + internationalization," supported by policy backing and enhanced global competitiveness [3] - There is an anticipated recovery in demand for domestic healthcare services by 2025, with potential improvements in the medical device sector as well [3] - AI in healthcare is highlighted as a significant technological trend that could bring new changes to the pharmaceutical industry [3] - Long-term prospects suggest that companies with strong innovation capabilities and rich product pipelines will benefit from ongoing procurement initiatives in pharmaceuticals and consumables [3]

生物医药ETF（159859）紧密跟踪国证生物医药指数（399441.SZ）。该指数以沪深北交易所属于生物 医药产业相关上市公司为样本空间，根据市值规模和流动性的综合排名，选出前30只证券作为指数样本 股，反映了生物医药行业的整体运行情况，向市场提供了细分行业的指数化投资标的。该ETF还配备了 联接基金（A：011040，C：011041）。 创新药沪港深ETF（517380）紧密跟踪恒生沪深港创新药50指数（HSSSHID.HI），该指数为唯一横跨 三地的创新药指数，精选50只优质创新药龙头。截至5月20日，该指数近5年市销率分位数32.18%。 创新药沪港深ETF 100%布局创新药产业链，前十大权重合计占比超50%，涵盖恒瑞医药、百济神州、 信达生物等热门标的。 招银国际认为，受益于创新药出海交易、国内集采政策优化、创新药丙类医保目录落地、医疗设备招标 复苏、内需复苏等积极因素推动，医药行业有望在2025年继续迎来估值修复。 5月21日，A股三大指数集体上涨，创新药概念延续强势。 相关ETF方面，生物医药ETF（159859）截至发稿涨0.85%，成交额超2876万元，换手率0.83%，盘中 交投活跃。 ...

Group 1 - The pharmaceutical sector is showing signs of recovery after four consecutive years of decline, with over 80% of pharmaceutical-related thematic funds rising as of May 16, and 11 products achieving over 30% growth, led by Changcheng Pharmaceutical Industry Select A with a 42.48% year-to-date return [1] - The performance of Hong Kong stocks in innovative drugs is notable, with the Hong Kong Stock Connect Innovative Drug Index rising by 28.37% year-to-date. The concentration in innovative drug stocks is a key factor in the performance of pharmaceutical thematic funds, with top-performing funds heavily invested in Hong Kong innovative drug stocks [3] - There has been significant capital inflow into innovative drug-themed ETFs, with several funds receiving net inflows of hundreds of millions since the second quarter. Additionally, there has been an increase in applications for new pharmaceutical funds, with at least 23 funds applying for approval in the last three months, over half of which are initiated products [3] Group 2 - The rise of innovative drugs is attributed to policy support, optimized procurement rules, and accelerated R&D progress by leading pharmaceutical companies. The future of the sector looks promising as domestic innovative drugs expand internationally and commercialization efforts advance [3] - Comparisons between A-share and Hong Kong markets indicate that Hong Kong innovative drug companies have less valuation bubble and more quality assets, while A-shares have many companies transitioning from generic to innovative drugs, suggesting greater potential for valuation increases [4] - AI in healthcare is becoming a focal point for institutional investors, with innovative drugs seen as mid-term high-probability assets and AI healthcare as a favorable opportunity, introducing new variables to the pharmaceutical sector [4]

Group 1 - The Hong Kong stock market experienced a collective rise, with the Hang Seng Index up by 0.74% and the Hang Seng Tech Index up by 0.8% [1] - The Hong Kong Innovative Drug ETF (159567) increased by 1.71%, with a turnover rate of 6.72% and a trading volume exceeding 115 million yuan, indicating active trading [1] - Key stocks in the ETF saw significant gains, with Junshi Biosciences rising over 9%, CanSino Biologics up over 8%, and Kelun Pharmaceutical increasing over 7% [1] Group 2 - Industry analysts believe that the innovative drug sector's growth is sustainable, driven by a combination of innovation and internationalization, supported by policies and increasing global competitiveness [1] - The innovative drug sector is expected to be a key investment theme for the pharmaceutical sector in 2025, with signs of recovery in domestic demand and improvements in the medical device sector [2] - AI in healthcare is anticipated to bring new changes to the pharmaceutical industry, highlighting the importance of this trend [1]

Core Viewpoint - Alibaba Health reported strong financial results for the fiscal year 2025, marking the third consecutive year of revenue and net profit growth, driven by increased user engagement and innovation in its business model [1][2][4]. Financial Performance - For the fiscal year 2025, Alibaba Health achieved a revenue of 30.598 billion yuan, representing a year-on-year growth of 13.2% [2]. - The net profit for the same period was 1.432 billion yuan, showing a significant increase of 62.2% year-on-year [2]. - Adjusted net profit reached 1.95 billion yuan, up 35.6% compared to the previous year [1][2]. Historical Performance - Alibaba Health's revenue has shown a consistent upward trend, increasing from 9.596 billion yuan in fiscal year 2020 to 30.598 billion yuan in fiscal year 2025 [3]. - The net profit has fluctuated but generally trended upwards, from a loss of 6.586 million yuan in fiscal year 2020 to a profit of 1.432 billion yuan in fiscal year 2025 [3]. Business Development - The company has enhanced its one-stop healthcare service capabilities, focusing on improving user experience through better product offerings and services [4]. - The Tmall Health platform has seen steady growth, with a significant increase in annual GMV and active users, and the number of online products grew by over 91% to 133 million [4]. Investment in Innovation - Alibaba Health invested 720 million yuan in product development during fiscal year 2025, focusing on AI technology, business optimization, and digital traceability [5]. - The company’s self-operated pharmaceutical business generated over 26.124 billion yuan in revenue, reflecting a year-on-year growth of 10% [5]. Market Position and Stock Performance - Alibaba Health's stock price saw a cumulative increase of over 60% in February and March due to the recovery of the Hong Kong tech sector and interest in AI healthcare concepts, but has since declined [7]. - As of May 20, the stock price was 4.89 HKD per share, with a total market capitalization of 78.7 billion HKD [7].