近日，桂格在上海隆重举办"桂格益生菌发酵燕麦即食燕麦片新品上市暨品牌焕新发布会"，宣布推出中国 第一个发酵燕麦片产品。桂格将专研的燕麦发酵技术用于新品中，以"后生元+益生元"双重自护助力中国 消费者肠道平衡，开启功能性燕麦时代。 相比于普通燕麦，添加了发酵燕麦粉的燕麦在营养性和功能性上都得到了强化。桂格团队历时3年开发了 专研燕麦发酵工艺，在燕麦粉中引入精选的五大益生菌[]进行24小时恒温发酵，使得燕麦粉中的大分子营 养物质被分解成更易吸收的小分子活性物质。这一过程不仅提升了燕麦的营养利用率，益生菌发酵后还产 生了有益代谢物——后生元。桂格把燕麦发酵后的这种有益营养和燕麦本身含有的益生元组合一起称之 为"桂格超能纤维Q"，形成了"燕麦.益生元+发酵.后生元"的双重营养，协同促进肠道健康，关爱自护力。 为进一步佐证后生元在燕麦中的健康效应，百事集团与东南大学等权威院校及机构合作，对产品进行了30 天真人试吃的实证研究。结果证明参与受试者的肠道舒适感、肠道有益菌和免疫炎症因子均有明显的改 善。在"燕麦益生元+发酵后生元"的营养叠加下，桂格超能纤维Q实现了肠道舒服和关爱自护力。 目前桂格益生菌发酵燕麦即食燕麦片已经 ...

排版丨水成文 代谢功能障碍相关脂肪性肝病 （MASLD） ，此前被称为非酒精性脂肪肝病 （NAFLD） ，正日益受到关注，成为全球 性的健康危机。它涵盖了从单纯脂肪变性到代谢功能障碍相关脂肪性肝炎 （MASH） 的范围，病情可能会发展为肝纤 维化、肝硬化，甚至肝细胞癌。 尽管 MASLD 的负担沉重且其病理生理学复杂，但目前仅有 1 种药物 （瑞美替罗） 获批专门用于 MASH 的治疗，这 凸显了迫切需要更多替代策略，其中 益生元 已崭露头角，成为颇具前景的候选方案。 2025 年 11 月 2 0 日， 上海交通大学医学院附属第六人民医院 李华婷 教授、上海交通大学数学科学学院 / 人工智能 学院 陈洛南 教授、上海交通大学医学院附属第六人民医院 倪岳琼 研究员、上海科技大学 / 上海临床研究中心 曾嵘 教 授及上海交通大学医学院附属第六人民医院 贾伟平 教授等， 在 Cell 子刊 Cell Metabolism 上 发表了题为： Interindividual variability in gut microbiome mediates the efficacy of resistant starch ...

Core Insights - The beverage industry is increasingly integrating probiotics into their products, with brands like Luckin Coffee and Nayuki Tea launching probiotic drinks at competitive prices, attracting consumer interest [1][3][4] - The trend of adding probiotics to beverages is not new, but it has evolved from simple yogurt drinks to more sophisticated formulations, enhancing consumer experience and product efficiency [4][7] - The probiotic market in China is experiencing significant growth, with a projected annual growth rate of 11% to 12%, potentially reaching a market size of 137.7 billion yuan by 2026 [12][13] Group 1: Probiotic Beverage Innovations - Recent launches include Luckin's probiotic American coffee and Nayuki's probiotic milkshake, which sold over 500,000 cups in just three days [1][4] - The introduction of instant probiotics in drinks, such as Tea Yan Yue Se's probiotic iced drinks, showcases the industry's shift towards more convenient and innovative product offerings [5][8] - The combination of ready-to-drink tea and probiotics is appealing to consumers, providing a healthier image for traditional beverages [8] Group 2: Market Dynamics and Consumer Trends - The probiotic beverage segment is gaining traction, with major dairy brands like Yili and Mengniu investing in probiotic products, indicating a shift in consumer preferences towards health-oriented options [9][10] - Probiotic dairy products accounted for 36.9% of the probiotic market share, with sales reaching 710 million yuan in Q1 2024, reflecting a growing consumer demand [10] - A significant portion of the Chinese population, 87.6%, experiences gut health issues, leading to increased interest in probiotic solutions [13][14] Group 3: Future Growth Opportunities - The ongoing innovation in probiotic beverages is expected to create new growth points, as consumers seek healthier lifestyle choices [22] - The industry is moving towards a more health-conscious approach, with products incorporating not just probiotics but also prebiotics and other functional ingredients [19][21] - The global probiotic beverage market is projected to grow significantly, with an expected market size of approximately $40.1 billion by 2025, indicating a robust demand for these products [19]

百事(PEP.O)推出益生元可乐。 ...

Core Insights - The probiotic market in China is projected to exceed 200 billion yuan by 2025, with billion-level live bacteria products becoming the core growth category [2] - The understanding of gut microbiota's role in health is expanding, linking it to digestion, immunity, inflammation, and even mental health [2] Group 1: Definition and Characteristics of Healthy Gut Microbiota - There is currently no fixed standard to define what constitutes a "healthy" gut microbiota [4] - Healthy gut microbiota typically exhibits high diversity, the ability to produce short-chain fatty acids, and stability against external disturbances [6][20] - The ideal composition of gut microbiota remains undetermined, as research is still ongoing [7] Group 2: Probiotic Testing and Its Reliability - The accuracy of gut microbiota testing is generally reliable, with most companies capable of providing accurate reports based on fecal samples [8][10] - However, these tests do not provide comprehensive guidance on optimizing gut health, especially in healthy individuals [10] - Testing can be particularly beneficial for diagnosing specific diseases like inflammatory bowel disease [11] Group 3: Dietary Influences on Gut Health - Different dietary practices, such as consuming fermented foods and high-fiber diets, can positively influence gut microbiota [15][24] - Long-term studies indicate that high-fiber and fermented food diets can enhance microbial diversity and reduce inflammation [26] - The consumption of probiotics may yield short-term benefits, but maintaining a diverse diet is more effective for long-term gut health [23][28] Group 4: Lifestyle Factors Affecting Gut Microbiota - Regular exercise has been shown to improve gut health by enhancing the production of short-chain fatty acids [32][33] - Sleep quality also plays a role, with evidence suggesting that sleep deprivation can temporarily disrupt gut microbiota diversity [35] - Close living conditions, such as with pets or family, can lead to microbiota similarities due to shared environments [36][37] Group 5: Probiotic Supplementation and Selection - The effectiveness of probiotic supplements depends on the viability of the bacteria, with live bacteria being essential for health benefits [43] - When selecting probiotics, factors such as the number of live bacteria and the specific strains should be considered [44][45] - The market for probiotics is large, but regulatory oversight is limited, leading to potential misinformation about health benefits [51][52]

Core Viewpoint - Obesity is a global health crisis affecting over 600 million people, linked to serious complications such as type 2 diabetes, cardiovascular diseases, and cancer. Current strategies focus on direct metabolic regulation, but modulating gut microbiota to limit nutrient availability presents a promising alternative [1][2]. Group 1: Research Findings - The study published by researchers from the RIKEN Institute indicates that acetylated cellulose (AceCel) suppresses body mass gain by enabling gut commensals to consume host-accessible carbohydrates, highlighting its potential as a prebiotic [2][10]. - Gut microbiota plays a significant role in metabolizing nutrients and influencing diseases, with gut microbiota accounting for 2.5%-5% of total energy supply in humans and about 8% in mice [4]. - The research demonstrates that AceCel significantly alters gut bacterial composition and function, reducing weight gain in both wild-type and obese mice by limiting carbohydrate oxidation in the liver and promoting fatty acid oxidation [8][11]. Group 2: Mechanism of Action - AceCel enhances the fermentation of carbohydrates by gut symbionts, specifically Bacteroides thetaiotaomicron, leading to a reduction in host-accessible monosaccharides and energy intake [8][11]. - The study emphasizes the importance of acetate, a short-chain fatty acid, in modulating the interaction between gut bacteria and host metabolism, suggesting that acetate's delivery to the distal colon can improve various metabolic indicators [5][6]. Group 3: Implications for Obesity Treatment - The findings underscore the potential of AceCel as a prebiotic that can regulate carbohydrate metabolism in both bacteria and hosts, offering new hope for obesity prevention and treatment strategies [10][11].