民以食为天，《零售圈》便在这一年的诸多事件中，遴选十大事件，和诸位一起，尝一口2025年食品零 售行业的真实滋味。 文 |零售圈 刚刚过去的2025年，零售食品行业仿佛一锅慢炖的浓汤，在看似平静的表面下，滋味却悄然发生了变 化。走进超市、打开外卖软件，甚至刷一刷短视频，你会发现：我们每天关心的"吃"，正被一系列事件 悄悄改写。 从年初辣条巨头卫龙的"老将回归"，到年末香飘飘从货架走向街边店；从千禾因"零添加"三个字引发的 信任风波，到养乐多关闭在华第一家工厂的背影——这一年的食品行业，既有老品牌的转身探索，也有 新消费故事的起落更迭。零售食品不再只是货架上的普通商品，它被不断演进的消费时代，赋予了如代 际传承，渠道边界，中国胃口等更加丰富的标签。 如果说过去我们谈论食品行业，总绕不开"销量""渠道""营销"这些词，那么2025年，话题明显变得更丰 富了：消费者开始认真查看配料表，企业重新思考谁该掌舵，老品牌努力靠近年轻人，外资巨头加紧整 合本土资产。这一切，都让"吃"这件事，在2025年显得既充满变数，又始终扎根于最真实的生活需求。 01 "辣条第一股"卫龙掌舵人变动，回归创始人家族掌控 2025年3月，"辣 ...

浙江省农业科学院食品科学研究所李进军主任详解"膳食纤维与益生元科学营养评价"方法，为产业发展 提供技术支撑；上海大学附属411医院赵珺主任、首都医科大学附属北京天坛医院刘君副主任医师等， 分别从慢病管理、癫痫防治、肿瘤免疫等临床视角，分享了膳食纤维在疾病干预中的实践经验与研究发 现；清华海峡研究院医学营养研究中心邹爱标主任发布"十万例真实世界研究二型糖尿病患者最新进展 与成果"，用详实数据验证了膳食纤维干预的临床价值。华大营养微生态检测负责人唐林仪则介绍了"菌 群检测+AI赋能"在膳食纤维研究中的应用，为精准科普、个性化健康方案制定提供技术支撑。 主题演讲后，大会学术执行主席杨怀义研究员均进行了精彩点评与解读，他提出的"可结合基因组技术 量化益生元的健康效果" 观点，为研究落地提供了新方向，进一步深化了演讲内容的学术价值。 来源：环球网 12月17日，2025益生元与"膳食纤维科普工程"年度会议暨益生元与膳食纤维临床研究合作意向开启在北 京协和医院学术会堂圆满举行。本次会议由中国生物医药技术协会膳食纤维技术分会主办、北京亦城合 作发展基金会指导，轻又清与加拿大Bionuetra联合承办。 中国生物医药技术协会 ...

Core Insights - Quaker has launched China's first fermented oat product, utilizing specialized fermentation technology to enhance gut health for consumers [1][3] Group 1: Product Development - The new product incorporates fermented oat powder, which has been developed over three years, enhancing nutritional absorption by breaking down large molecules into smaller, more absorbable active substances [3] - The fermentation process introduces five selected probiotics, resulting in beneficial metabolites known as postbiotics, which work alongside prebiotics found in oats to promote gut health [3][4] Group 2: Health Benefits - A 30-day human trial conducted in collaboration with Southeast University showed significant improvements in gut comfort, beneficial gut bacteria, and immune inflammatory factors among participants [4] - The combination of oat prebiotics and fermented postbiotics in the product, branded as "Quaker Super Fiber Q," aims to enhance gut health and self-care capabilities [4] Group 3: Market Positioning - Quaker's new product is positioned to address the common gut health issues faced by over 80% of Chinese consumers, such as abdominal pain, bloating, and constipation, which are often not widely recognized [5] - The product is designed to meet the increasing demand for functional and health-oriented food options among Chinese consumers, who seek to improve their dietary habits [5] Group 4: Brand Strategy - Quaker is launching a "30 Days to Rebalance" challenge on social media to encourage consumers to improve their gut health through consistent consumption of the new fermented oat product [5] - The brand's new mission reflects a commitment to bridging traditional dietary wisdom with modern consumer needs, aiming to provide balanced nutrition for various life stages [6]

Core Insights - Metabolic dysfunction-associated fatty liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), is increasingly recognized as a global health crisis, with potential progression to severe liver conditions [3] - Currently, only one drug, Remetiro, is approved specifically for the treatment of metabolic dysfunction-associated steatohepatitis (MASH), highlighting the urgent need for alternative strategies, with prebiotics emerging as a promising candidate [3] Research Findings - A study published in Cell Metabolism revealed that individual variability in gut microbiome mediates the efficacy of resistant starch (RS) on MASLD, indicating that different baseline gut microbiomes can drive variations in intervention responses [4] - The research team conducted a randomized, placebo-controlled clinical trial showing that RS, a natural prebiotic, has therapeutic effects on MASLD, although 30% of participants exhibited limited benefits, a finding corroborated in a multicenter clinical trial [6] - Multi-omics analysis and fecal microbiota transplantation (FMT) indicated that baseline gut microbiome is a major determinant of treatment response, with Prevotella inhibiting the degradation of RS, leading to low response rates [7] - Bifidobacterium pseudocatenulatum was isolated from the cohort, which can restore RS degradation and improve the response to RS inhibited by Prevotella [7] - A predictive model integrating baseline microbiome and clinical characteristics was developed, achieving an AUC of 0.74 - 0.87 for personalized intervention [8] Key Findings - Approximately one-third of MASLD participants showed poor response to RS intervention [11] - Prevotella mediates low response to RS by inhibiting RS-degrading bacteria [11] - Bifidobacterium pseudocatenulatum enhances the efficacy of RS [11] - A machine learning model based on baseline gut microbiome characteristics can predict responses to RS treatment [11] - The study suggests that gut microbiome determines the heterogeneity of RS treatment for MASLD, offering a potential for microbiome-guided precision therapy [12]

Core Insights - The beverage industry is increasingly integrating probiotics into their products, with brands like Luckin Coffee and Nayuki Tea launching probiotic drinks at competitive prices, attracting consumer interest [1][3][4] - The trend of adding probiotics to beverages is not new, but it has evolved from simple yogurt drinks to more sophisticated formulations, enhancing consumer experience and product efficiency [4][7] - The probiotic market in China is experiencing significant growth, with a projected annual growth rate of 11% to 12%, potentially reaching a market size of 137.7 billion yuan by 2026 [12][13] Group 1: Probiotic Beverage Innovations - Recent launches include Luckin's probiotic American coffee and Nayuki's probiotic milkshake, which sold over 500,000 cups in just three days [1][4] - The introduction of instant probiotics in drinks, such as Tea Yan Yue Se's probiotic iced drinks, showcases the industry's shift towards more convenient and innovative product offerings [5][8] - The combination of ready-to-drink tea and probiotics is appealing to consumers, providing a healthier image for traditional beverages [8] Group 2: Market Dynamics and Consumer Trends - The probiotic beverage segment is gaining traction, with major dairy brands like Yili and Mengniu investing in probiotic products, indicating a shift in consumer preferences towards health-oriented options [9][10] - Probiotic dairy products accounted for 36.9% of the probiotic market share, with sales reaching 710 million yuan in Q1 2024, reflecting a growing consumer demand [10] - A significant portion of the Chinese population, 87.6%, experiences gut health issues, leading to increased interest in probiotic solutions [13][14] Group 3: Future Growth Opportunities - The ongoing innovation in probiotic beverages is expected to create new growth points, as consumers seek healthier lifestyle choices [22] - The industry is moving towards a more health-conscious approach, with products incorporating not just probiotics but also prebiotics and other functional ingredients [19][21] - The global probiotic beverage market is projected to grow significantly, with an expected market size of approximately $40.1 billion by 2025, indicating a robust demand for these products [19]

Core Insights - PepsiCo has launched a new probiotic cola, indicating a strategic move towards health-conscious beverage options [1] Company Summary - The introduction of the probiotic cola aligns with current consumer trends favoring functional beverages that offer health benefits [1] - This product launch may enhance PepsiCo's competitive positioning in the beverage market, particularly against rivals focusing on health and wellness [1] Industry Summary - The beverage industry is increasingly shifting towards products that incorporate health benefits, reflecting changing consumer preferences [1] - The launch of probiotic beverages could signify a broader trend within the industry, as companies adapt to meet the demand for healthier options [1]

Core Insights - The probiotic market in China is projected to exceed 200 billion yuan by 2025, with billion-level live bacteria products becoming the core growth category [2] - The understanding of gut microbiota's role in health is expanding, linking it to digestion, immunity, inflammation, and even mental health [2] Group 1: Definition and Characteristics of Healthy Gut Microbiota - There is currently no fixed standard to define what constitutes a "healthy" gut microbiota [4] - Healthy gut microbiota typically exhibits high diversity, the ability to produce short-chain fatty acids, and stability against external disturbances [6][20] - The ideal composition of gut microbiota remains undetermined, as research is still ongoing [7] Group 2: Probiotic Testing and Its Reliability - The accuracy of gut microbiota testing is generally reliable, with most companies capable of providing accurate reports based on fecal samples [8][10] - However, these tests do not provide comprehensive guidance on optimizing gut health, especially in healthy individuals [10] - Testing can be particularly beneficial for diagnosing specific diseases like inflammatory bowel disease [11] Group 3: Dietary Influences on Gut Health - Different dietary practices, such as consuming fermented foods and high-fiber diets, can positively influence gut microbiota [15][24] - Long-term studies indicate that high-fiber and fermented food diets can enhance microbial diversity and reduce inflammation [26] - The consumption of probiotics may yield short-term benefits, but maintaining a diverse diet is more effective for long-term gut health [23][28] Group 4: Lifestyle Factors Affecting Gut Microbiota - Regular exercise has been shown to improve gut health by enhancing the production of short-chain fatty acids [32][33] - Sleep quality also plays a role, with evidence suggesting that sleep deprivation can temporarily disrupt gut microbiota diversity [35] - Close living conditions, such as with pets or family, can lead to microbiota similarities due to shared environments [36][37] Group 5: Probiotic Supplementation and Selection - The effectiveness of probiotic supplements depends on the viability of the bacteria, with live bacteria being essential for health benefits [43] - When selecting probiotics, factors such as the number of live bacteria and the specific strains should be considered [44][45] - The market for probiotics is large, but regulatory oversight is limited, leading to potential misinformation about health benefits [51][52]

Core Viewpoint - Obesity is a global health crisis affecting over 600 million people, linked to serious complications such as type 2 diabetes, cardiovascular diseases, and cancer. Current strategies focus on direct metabolic regulation, but modulating gut microbiota to limit nutrient availability presents a promising alternative [1][2]. Group 1: Research Findings - The study published by researchers from the RIKEN Institute indicates that acetylated cellulose (AceCel) suppresses body mass gain by enabling gut commensals to consume host-accessible carbohydrates, highlighting its potential as a prebiotic [2][10]. - Gut microbiota plays a significant role in metabolizing nutrients and influencing diseases, with gut microbiota accounting for 2.5%-5% of total energy supply in humans and about 8% in mice [4]. - The research demonstrates that AceCel significantly alters gut bacterial composition and function, reducing weight gain in both wild-type and obese mice by limiting carbohydrate oxidation in the liver and promoting fatty acid oxidation [8][11]. Group 2: Mechanism of Action - AceCel enhances the fermentation of carbohydrates by gut symbionts, specifically Bacteroides thetaiotaomicron, leading to a reduction in host-accessible monosaccharides and energy intake [8][11]. - The study emphasizes the importance of acetate, a short-chain fatty acid, in modulating the interaction between gut bacteria and host metabolism, suggesting that acetate's delivery to the distal colon can improve various metabolic indicators [5][6]. Group 3: Implications for Obesity Treatment - The findings underscore the potential of AceCel as a prebiotic that can regulate carbohydrate metabolism in both bacteria and hosts, offering new hope for obesity prevention and treatment strategies [10][11].