Summary of Key Points from Conference Call Records Industry Overview - The conference call discusses the performance of various industries, particularly focusing on industrial enterprises, public utilities, and manufacturing sectors in a low-interest-rate environment. The overall profit share of industrial enterprises is expected to remain above 15% in 2023-2024, with a slight decline to 12.5% in the first half of 2025, still higher than the pre-pandemic average of 5.9% [1][2]. Core Insights and Arguments - **Profit Recovery in Key Sectors**: Industrial enterprises' profit share has significantly rebounded, with public utilities also seeing an increase to 12.1% as of mid-2023, up from a pre-pandemic average of 6.9% [2]. - **Manufacturing Sector Decline**: Manufacturing profit share has decreased to approximately 75%, with export-oriented industries like computers and electronics maintaining stable profits due to overseas demand recovery [1][2]. - **Mining Sector Volatility**: The mining sector's profits have been affected by fluctuations in the Producer Price Index (PPI), with a notable decline in 2023 due to commodity price adjustments and insufficient demand [1][4]. - **Investment Returns**: High capital return rates are observed in public utilities, coal, and petrochemical sectors, while the real estate sector shows lower returns, particularly since 2021 [5]. Additional Important Insights - **Driving Factors for Profit Changes**: Key drivers include price fluctuations, overseas demand, policy support for equipment updates, and consumer recovery in sectors like beverages and metals [4]. - **Sector-Specific Performance**: High-performing sub-sectors include energy metals, coal, oil and gas extraction, aerospace, and electronics, with strong growth potential in smaller segments despite overall weaker performance in some primary categories [6]. - **Impact of PPI on Utilities**: A decrease in mining PPI has alleviated cost pressures for public utilities, leading to a recovery in profit margins, although this trend may reverse due to insufficient end-demand [7]. - **China's Export Dynamics**: China's export share has improved due to pandemic-related shifts, with a temporary recovery in 2023-2024 driven by inventory replenishment in Western manufacturing [8]. - **Outward Expansion of Chinese Enterprises**: The trend of Chinese companies expanding overseas has positively impacted profitability, particularly in home appliances, non-ferrous metals, and machinery sectors [9][10]. - **Policy Support for Emerging Industries**: Recent industrial policies emphasize the importance of maintaining industrial security and promoting new industrialization, benefiting sectors like energy metals and biomanufacturing [11]. - **Growth Potential in Service Consumption**: There is significant potential for growth in service consumption, with government initiatives aimed at enhancing domestic demand and expanding service sectors such as health care and home services [12].

北京商报讯（记者 金朝力 程靓）8月13日，据北京市经济和信息化局消息，工业和信息化部于昨日发布 了《人工智能在生物制造领域典型应用案例（第一批）》，全国共有16家企业应用案例入选，北京市3 家企业上榜，入选数量与上海市并列全国第一。其中，北京诚益通控制技术集团股份有限公司"应用 SemDB数据库技术实现大规模生物制造过程全链条精准工艺控制和AI大数据分析"、北京昭衍生物技术 有限公司"智能化AI平台驱动的稳定高表达细胞株构建"获评优秀等级；百图生科（北京）智能技术有限 公司"基于AI大模型高效改造药用酶用于酶替代疗法"获评典型等级。北京市将进一步推动人工智能与生 物制造深度融合，促进生物制造全产业链提质升级。 ...

Group 1 - The article highlights the transformation of Taohua Mountain from a historical site of resistance during the Anti-Japanese War to a modern integrated tourism, leisure, and vacation forest park, leveraging red culture and ecological resources [6][10] - The local economy has diversified with the development of specialty agriculture and cultural tourism projects, leading to significant improvements in living standards and the eradication of poverty in 28 villages by 2017 [10][18] - The region has seen a substantial increase in agricultural productivity, with over 5,000 acres of wrinkled tangerines bearing fruit, indicating a successful agricultural initiative [8][10] Group 2 - Huarong County has actively aligned with the Yangtze River Economic Belt development strategy, enhancing its industrial layout, including the recent launch of a coal-water transport and storage base [12][14] - The county's industrial structure has evolved to focus on modern agriculture, green food processing, textile manufacturing, general equipment manufacturing, and biomanufacturing, with 60 national high-tech enterprises and 27 specialized enterprises [16] - The GDP of Huarong County has increased from 20.41 billion yuan in 2012 to 41.67 billion yuan in 2024, while rural residents' per capita disposable income has risen from 8,860 yuan to 30,296 yuan, marking a 241.9% increase [18]

Core Points - The fourth Synthetic Biology and Green Bio-Manufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI with bio-manufacturing, green chemicals, new materials, future food, and future agriculture [2][3] - The conference aims to explore the development trends of the bio-manufacturing industry during the 14th Five-Year Plan, innovations driven by AI, and the technologies and products that will sustain the vitality of the bio-manufacturing sector [2][3] - Various activities will take place during the conference, including a Youth Forum on Bio-Manufacturing, a high-level roundtable discussion, and a closed-door seminar on the "2025 AI Empowering Bio-Manufacturing Industry Innovation Development Blue Book" [2][3][20] Organizational Structure - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and co-organized by several institutions, including Peking University Ningbo Institute of Ocean Medicine and Ningbo Meisai Bioengineering Co., Ltd. [3] - Supporting organizations include the Chinese Society of Biotechnology's Bio-based Materials Committee and various regional bio-manufacturing alliances [3] Conference Agenda - The agenda includes registration, high-level discussions, and thematic forums on topics such as green chemicals and new materials, AI-driven innovations in bio-manufacturing, and future food and agriculture [6][7][21] - Specific sessions will cover topics like enzyme molecular engineering, bio-based carboxylic acid conversion, and the design of humanized "4D" collagen proteins [11][12][17][25] Special Acknowledgments - Several companies and institutions have been acknowledged for their support, including Ningbo Meisai Bioengineering Co., Ltd., Peking University Ningbo Institute of Ocean Medicine, and various technology firms [4] Industry Insights - The conference will also feature the release of the "China Synthetic Biology Industry Distribution Map (2025 Edition)" and a list of over 500 representative bio-manufacturing enterprises in China [50][51] - The event aims to facilitate technology transfer, product scaling, and talent acquisition within the bio-manufacturing sector [2][3]

Core Viewpoint - The article discusses the construction project of a collagen production line by Shandong Furida Biotechnology Co., Ltd., highlighting its investment, production capacity, and timeline for completion [2]. Summary by Sections Project Progress - Shandong Furida Biotechnology Co., Ltd. is expanding its collagen production line, located in Linyi City, Shandong Province, with a total investment of 12 million yuan, including 500,000 yuan for environmental protection [2]. - The project will utilize existing facilities and is expected to produce 200 kg of collagen annually upon completion in June 2025 [2]. Existing Project Status - The company has several ongoing projects, including: - Sodium hyaluronate project with an annual output of 50 tons [4]. - Various fermentation projects with different production capacities, including: - Recombinant Type II collagen: 115.2 kg/a - Recombinant Type XVII collagen: 64 kg/a - Recombinant Type III transmembrane collagen: 20.8 kg/a - The total annual production capacity for collagen will reach 200 kg [3][4]. Industry Events - The fourth Synthetic Biology and Green Bio-Manufacturing Conference (SynBioCon 2025) will be held from August 20-22, 2025, in Ningbo, Zhejiang Province, focusing on AI and bio-manufacturing, green chemicals, new materials, future food, and agriculture [8][9].

Core Viewpoint - The article highlights the approval of the "Regulations on Promoting the Development of Synthetic Biology Manufacturing Industry in Changde City," marking a significant step in the local government's efforts to foster the synthetic biology sector and establish a national-level industrial cluster [2]. Group 1: Legislative Developments - The Changde City government has prioritized the development of the synthetic biology manufacturing industry, creating a multi-faceted industrial landscape across various regions such as Jinshi City, Anxiang County, and Changde Economic Development Zone [2]. - The "Regulations" represent the first local legislation in the synthetic biology manufacturing field in China, consisting of 19 articles covering objectives, scope, government responsibilities, innovation platform construction, and more [2]. Group 2: Upcoming Events - The 4th Synthetic Biology and Green Bio-Manufacturing Conference (SynBioCon 2025) will be held from August 20-22, 2025, in Ningbo, Zhejiang, focusing on the intersection of AI and bio-manufacturing, as well as advancements in green chemicals, new materials, future food, and agriculture [4][5]. - The conference will feature various activities, including a youth forum, high-level discussions, and a closed-door seminar on the "2025 Blue Book for AI-Enabled Bio-Manufacturing Industry Innovation Development" [5].

1 # and In 大量素材料大學杭州研究 TERRET in The 实 验 金 湖 湘 XIANGHU PANI BILA © | AHT 浙江省北大信息技术高等研究院 高能级科创平台牵引下的"科创引领，数实融合"一直是萧山打破路径依赖、实现转型跃升的核心引 擎。7年时间，萧山先后打造了六大高能级科创平台，实现R&D经费投入总量从46.28亿元增长至87.05 亿元（R&D经费占GDP比重从2.57%增长至3.9%），杭州市A-E类高层次人才从437人扩大至14828人， 高新技术产业增加值占比从42.43%提高至69.07%。 案例就是路径。问及"诀窍"，萧山区科技局相关负责人表示，主要得益于处理好了"高校与政 府""高校与平台""平台与企业""平台与产业""平台与人才"的"五对关系"，同时通过"教科人一体化"改革 重塑区域创新生态，为科创新质生产力的发展营造优沃土壤。 从"补短板"到"强磁场"的七年深耕 六大高能级科创平台，是北大信息技术高等研究院、浙大杭州国际科创中心、西电杭州研究院、浙 大计算机创新技术研究院、巴顿焊接技术研究院和湘湖实验室，分别瞄准人工智能、集成电路、生物制 造、先进材料等未来 ...

菌株是生物质炼制的 "芯片"，是以生物质为原材料的新型生物制造产业链和绿色低碳生物经济的核心。 用于生物制造的菌株细胞通常面临中间代谢产物积累、毒性产物抑制，导致反应效率低、终产物浓度低的问题，严重制约了绿色生物制造的发展。因 此，" 如何构建菌株细胞并强化反应过程合成生物基产品 "是该领域重要的研究课题。 以" 菌株细胞工厂构建及产物合成强化 "为核心，以" 人工细胞器创制、菌株细胞工厂构建、反应分离耦合调控 "从微观到宏观强化产物生物合成，可 以强化生物制造过程。 多 年来， 大连理工大学薛闯教授 团队创建了多酶自组装蛋白质笼的人工细胞器，该人工细胞器可实现化学诱导、光诱导提升细胞器的可调节性，揭 示了人工细胞器的时空调控机制；创建了"多枪-多靶"快速菌株构建方法，揭示了磷酸化激酶多维度协同调控菌株的新机制，阐明了梭状芽孢杆菌群体 感应系统中信号分子自诱导肽的合成途径和调控功能；制备了碳纳米管阵列复合膜，开发了反应分离耦合技术。实现了 以生物能源为主的产品生物合 成强化 ， 为解决工业生物技术领域催化效率低的瓶颈问题提供了新突破点与新思路 。 点击更多阅读 ： 祝贺！80后生物制造专家-薛闯教授获大奖，全 ...

未来食品&农业 | 微元合成 【SynBioCon】 获 悉 ，近日，合成生物学领域的新锐力量—— 芝诺科技 ，成功完成了 数千万元 人民币的Pre-A轮融资 ，在此之前，芝诺科技已经完成了来自中信创投和嘉程资本等知名投资方的 历史 投资。 此次融资将为 芝诺科技 注入强大动力，助力公司在 生产能力提升、管线拓展、团队扩 张以及商业化落地等方面实现跨越性发展。 专题论坛3 来来最品&农业GEN 芝诺科技成立于2020年，是一家专注于合成生物学技术的国家高新技术企业，总部位于北京， 在苏 州、山东东营设有研发中心与百吨级生产基地 。公司核心团队汇聚了来自牛津大学、北京大学等顶 尖机构的跨学科人才，创始人朱天择博士深耕糖化学与代谢流优化十余年，其领衔的技术团队通过 CRISPR 等新一代基因编辑技术，实现工程菌产率较野生型提升千倍以上，生产效率较传统方法提 高十倍。 其关键技术亮点： ▌ 参考信息： 本文部分素材来自公开信息。由作者重新编写，系作者个人观点，本平台发布仅为了传达一种不同观点，不代表 对该观点赞同或支持。如果有任何问题，请联系我们：15356747796（微信同号）。 代谢流精准设计：构建覆盖模式菌 ...

Core Viewpoint - The article emphasizes that biomanufacturing is becoming a key engine for the transformation and upgrading of the chemical industry, driven by the global green transition and "dual carbon" goals [2]. Group 1: Biomanufacturing and Chemical Industry Transformation - Biobased materials, derived from renewable biomass such as starch, cellulose, and fats, are fundamentally changing the linear economic model of "mass production, mass consumption, and mass waste" through a circular economy approach [2]. - Synthetic biology and biomanufacturing utilize biomass as raw materials, leveraging the metabolic functions of microorganisms, cells, and enzymes to achieve large-scale production of target products [3]. - Key pathways for the green transformation of the chemical industry include the development of non-food biobased synthetic products, green biomanufacturing of plastic monomers like dicarboxylic acids and diols, utilization and conversion of one-carbon resources like CO2, and enzymatic recycling of waste plastics [3]. Group 2: Upcoming Conference and Expert Participation - The Fourth Synthetic Biology and Green Biomanufacturing Conference will be held from August 20-22 in Ningbo, Zhejiang, featuring a session on green chemicals and new materials with participation from prominent experts and representatives from biomanufacturing companies [4]. - Notable speakers include Professor Wang Dan from Chongqing University, Professor Xue Chuang from Dalian University of Technology, and Yang Shihui, founder of Wuhan Ruijia Kang, who will discuss various aspects of biomanufacturing and its applications [6][7]. Group 3: Conference Agenda Highlights - The conference will include discussions on cell factory design, microbial cell factories for plastic monomers, and green separation and purification technologies in synthetic biology [30][35]. - A special focus will be on the application of non-food biomass sugars in synthetic biology and green biomanufacturing, showcasing flexible production platforms [7]. - The agenda also features a series of forums on AI empowerment in biomanufacturing and future food and agriculture innovations [14][43]. Group 4: Industry Collaboration and Research - The conference is organized by DT New Materials in collaboration with various academic and research institutions, highlighting the importance of industry-academia partnerships in advancing biomanufacturing technologies [10][16]. - The event aims to promote the sharing of innovative research and practical applications in the field of biomanufacturing, contributing to the overall growth of the industry [39].