Core Viewpoint - The article emphasizes the importance of biomanufacturing as a key focus for enhancing economic competitiveness in various countries, including China, which is advancing its manufacturing capabilities through initiatives like green manufacturing and intelligent manufacturing [1]. Group 1: Event Overview - The Fourth Synthetic Biology and Green Biomanufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI and biomanufacturing, along with four major application areas: green chemicals and new materials, future food, future agriculture, and beauty raw materials [1]. - The conference aims to explore the development trends of the biomanufacturing industry during the 14th Five-Year Plan period and identify innovative technologies and products that will sustain the industry's vitality [1]. Group 2: Organizing Institutions - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and co-organized by Ningbo Meisai Biological Engineering Co., Ltd. It is supported by various professional committees and alliances in the field of biomanufacturing [2]. Group 3: Highlights of the Conference - The conference will feature forums and closed-door activities to gain insights into the development trends of biomanufacturing, explore new products and technologies, and foster new collaborations [4]. - There will be over 100 financing project roadshows to discover new cooperation opportunities and showcase innovative technological achievements [4]. - Key industry leaders, top universities, capital from parks, and the entire industry chain will gather to discuss advancements and opportunities in biomanufacturing [4]. Group 4: Agenda and Activities - The first day will include a closed-door seminar focusing on the development trends and growth points of biomanufacturing during the 14th Five-Year Plan, inviting 30 industry leaders and experts for in-depth discussions [9]. - The second and third days will feature a macro forum on biomanufacturing, specialized sub-forums on green chemicals, AI in biomanufacturing, future food and agriculture, and beauty raw materials, addressing various key topics and innovations in these fields [13]. - A special session for showcasing scientific achievements and project matchmaking will also be held, inviting 100 innovative projects in the biomanufacturing sector for display and collaboration [14].

Core Viewpoint - The article emphasizes the importance of biomanufacturing as a key focus for enhancing economic competitiveness in various countries, including China, which is advancing its manufacturing capabilities through initiatives like green manufacturing and intelligent manufacturing [1]. Group 1: Event Overview - The Fourth Synthetic Biology and Green Biomanufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI and biomanufacturing [1]. - The conference aims to explore the development trends of the biomanufacturing industry during the 14th Five-Year Plan and identify innovative technologies and products that will sustain the industry's vitality [1]. Group 2: Organizing Institutions - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and supported by various institutions, including the Chinese Society of Biotechnology and the Zhejiang Synthetic Biology Industry Technology Alliance [2]. Group 3: Conference Highlights - Key highlights include forums and closed-door discussions on biomanufacturing trends, youth innovation technology sharing, and over 100 financing project roadshows to discover new cooperation opportunities [4]. - The event will gather leading enterprises, top universities, investment institutions, and industry stakeholders to foster collaboration [4]. Group 4: Agenda and Activities - The first day features a closed-door seminar focusing on the development trends and growth points of biomanufacturing, inviting 30 industry leaders and experts for in-depth discussions [9]. - The second and third days will include a macro forum on biomanufacturing, specialized sub-forums on green chemicals, AI in biomanufacturing, future food and agriculture, and beauty raw materials [13]. Group 5: Specialized Topics - Sub-forums will cover various topics, including the development of bio-based chemicals, AI applications in enzyme discovery, and the biomanufacturing of high-value food ingredients [13]. - The conference will also showcase innovative projects and facilitate connections between research teams and industry players [12][14].

Core Viewpoint - The article emphasizes the importance of biomanufacturing as a key focus for enhancing economic competitiveness in various countries, including China, which is advancing its manufacturing capabilities through synthetic biology initiatives [1]. Group 1: Event Overview - The Fourth Synthetic Biology and Green Biomanufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI and biomanufacturing, along with four application areas: green chemicals and new materials, future food, future agriculture, and beauty raw materials [1]. - The conference aims to explore the development trends of the biomanufacturing industry during the 14th Five-Year Plan, identify innovative technologies and products, and promote the transfer and commercialization of scientific achievements [1]. Group 2: Organizing Institutions - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and supported by various institutions, including the Chinese Society of Biotechnology and the Zhejiang Synthetic Biology Industry Technology Alliance [2]. Group 3: Conference Highlights - Key highlights include forums and closed-door activities to gain insights into the biomanufacturing development trends, sharing of innovative technologies, and over 100 financing project roadshows to discover new cooperation opportunities [2]. - The event will also feature a youth innovation technology forum to connect talents and share valuable insights [2]. Group 4: Conference Agenda - The first day will include a closed-door seminar focusing on the development trends and growth points of biomanufacturing, inviting 30 industry leaders and experts for in-depth discussions [7]. - The second and third days will feature a macro forum on the biomanufacturing industry, covering various specialized topics such as green chemicals, AI in biomanufacturing, future food and agriculture, and beauty raw materials [10][12]. Group 5: Specialized Topics - Specialized forums will address topics like the development of bio-based chemicals, AI applications in enzyme discovery, and the biomanufacturing of high-value food ingredients [10][11]. - The conference will also showcase innovative projects and technologies in the field of synthetic biology and biomanufacturing, encouraging participation from research institutions and enterprises [12].

Core Viewpoint - The article emphasizes the importance of biomanufacturing as a key focus for enhancing economic competitiveness in various countries, including China, which is advancing its manufacturing capabilities through initiatives like green manufacturing and intelligent manufacturing [1]. Group 1: Event Overview - The Fourth Synthetic Biology and Green Biomanufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI and biomanufacturing [1]. - The conference aims to explore the development trends of the biomanufacturing industry during the 14th Five-Year Plan, discussing innovative technologies and products that can sustain the industry's vitality [1]. Group 2: Organizing Institutions - The conference is organized by Ningbo Detai Zhongyan Information Technology Co., Ltd. (DT New Materials) and co-organized by Ningbo Meisai Biological Engineering Co., Ltd. [2]. - Supporting organizations include the Chinese Society of Biotechnology's Biobased Materials Committee and various local industry alliances [2]. Group 3: Highlights of the Conference - The conference will feature forums and closed-door activities to gain insights into the development trends of biomanufacturing and explore new products, technologies, and collaborations [5]. - There will be over 100 financing project roadshows to discover new cooperation opportunities [5]. - Key industry leaders, top universities, and investment institutions will gather to discuss advancements in the biomanufacturing sector [5]. Group 4: Agenda and Activities - The first day will include a closed-door seminar focusing on the development trends and growth points of biomanufacturing [10]. - The second and third days will feature a macro forum on biomanufacturing, specialized sub-forums on green chemicals, AI in biomanufacturing, future food and agriculture, and beauty raw materials [14]. - A special session for showcasing scientific achievements and project matchmaking will also be held, inviting innovative projects from the biomanufacturing field [15].

Group 1: Forum Overview - The 2025 Changping Pharmaceutical Health Financial Investment Innovation Forum was successfully held to promote the development of China's pharmaceutical health industry and enhance Changping's status as an innovation hub [1][2] - The forum featured 18 prominent guests and nearly 200 participants from academia, industry, healthcare, and investment sectors, discussing industry development and capital support [2] Group 2: Government and Financial Support - Beijing State-owned Capital Operation Management Co., Ltd. is actively supporting the pharmaceutical health industry through capital layout optimization and industry transformation, establishing a 100 billion yuan municipal government investment fund [3] - The Beijing Pharmaceutical Health Industry Investment Fund, with a scale of 20 billion yuan, was established in Changping in 2024, focusing on innovative drugs and medical devices [3] - As of mid-2025, the fund has invested over 4 billion yuan, attracting more than 5 billion yuan in social investment [3] Group 3: Innovation and Technology Integration - AI technology is becoming a key driver for the clinical transformation of regenerative medicine, addressing challenges such as individual variability and complex tissue construction [4] - The integration of AI in drug development is reshaping the pharmaceutical industry, with platforms like PandaOmics and Chemistry42 enhancing efficiency in target discovery and molecular design [8] Group 4: Industry Trends and Future Outlook - China's pharmaceutical industry is transitioning from policy-driven to capability-driven, with a significant increase in innovative drug approvals expected by 2024 [7] - The market for innovative drugs in China is projected to exceed 300 billion USD by 2030, with a growing global market share [7] - The domestic medical device industry is accelerating its globalization, with increasing independence from foreign technologies and a focus on high-end medical equipment [11]

Core Viewpoint - The article emphasizes the importance of biomanufacturing as a key focus for enhancing economic competitiveness in various countries, including China, which is advancing its manufacturing capabilities through initiatives like green manufacturing and intelligent manufacturing [1]. Group 1: Event Overview - The Fourth Synthetic Biology and Green Biomanufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI and biomanufacturing [1]. - The conference aims to explore the development trends of the biomanufacturing industry during the 14th Five-Year Plan, discussing innovative technologies and products that can sustain the industry's vitality [1]. Group 2: Organizing Institutions - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and co-organized by Ningbo Meisai Bioengineering Co., Ltd. [2]. - Supporting organizations include the Chinese Society of Biotechnology's Biobased Materials Committee and various local industry alliances [2]. Group 3: Highlights of the Conference - The conference will feature forums and closed-door activities to gain insights into the development trends of biomanufacturing and explore new products, technologies, and collaborations [5]. - There will be over 100 financing project roadshows to discover new cooperation opportunities [5]. - Key players from leading enterprises, top universities, investment institutions, and industry stakeholders will gather to discuss advancements in the field [5]. Group 4: Agenda and Activities - The first day will include a closed-door seminar focusing on the development trends and growth points of biomanufacturing [10]. - The second and third days will feature a macro forum on biomanufacturing, specialized sub-forums on green chemicals, AI in biomanufacturing, future food and agriculture, and beauty raw materials [14]. - The conference will also host a technology achievement showcase to promote innovative results and projects in the biomanufacturing sector [15].

Core Viewpoint - The fourth Synthetic Biology and Green Bio-Manufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on industrial ecological development and the transfer of scientific achievements [1][10]. Group 1: Conference Overview - SynBioCon 2025 is organized by DT New Materials and supported by various organizations, aiming to facilitate over 1,000 connections between research institutions and startup projects [1]. - The conference will feature a special event showcasing 100 innovative achievements in synthetic biology manufacturing, promoting efficient technology transfer [1][9]. Group 2: Featured Project - The project "Synthesis of Selenium Protein from Microalgae" aims to address the issue of selenium deficiency in the Chinese population by using edible microalgae as a source of selenium protein [6]. - The research team has successfully transferred human selenium protein into the edible microalgae Chlorella vulgaris and has significantly increased the yield through optimized cultivation parameters [7]. Group 3: Technical Advantages - Chlorella vulgaris is recognized as a safe and reliable food source, approved by the National Health Commission, and can be cultivated through both photosynthesis and industrial fermentation [7]. - The project is currently in the pilot production stage after successful small-scale trials [7]. Group 4: Intellectual Property and Collaboration - The project is in the process of patent application, with potential collaboration modes including joint development, technology transfer, or intellectual property transfer [8]. Group 5: Industry Focus - The conference will explore the trends in the bio-manufacturing industry, focusing on AI and biological manufacturing, green chemicals, new materials, future food, future agriculture, and beauty raw materials [10].

Core Viewpoint - The article highlights the approval of alulose by the National Health Commission, marking the first instance of a company using synthetic biology to produce this new food ingredient in China [1][2]. Group 1: Approval and Technology - The AS10 strain fermentation method for producing alulose is the first case in China to receive approval for a new food ingredient using synthetic biology technology [2]. - The unique "one-step fermentation" process developed by the company simplifies production and enhances product quality compared to traditional methods [2][3]. Group 2: Cost Reduction and Market Potential - Previously, alulose production required a two-step conversion with an efficiency of only about 10%, leading to high market prices around 30,000 yuan per ton [4]. - With the optimization of synthetic biology technology, production costs are expected to decrease by 50%, potentially lowering prices to around 10,000 yuan per ton, which would significantly expand its market applications [5]. Group 3: Production Capacity and Future Plans - The company's first-phase alulose factory in Qinhuangdao has commenced operations, and a second-phase factory is set to begin production in 2027 [7]. - The company is also collaborating with traditional bio-manufacturing partners to upgrade multiple production capacities, with a 60,000-ton capacity project in North China expected to be operational by October 2025, positioning the company as the largest alulose supplier globally [8].

Core Viewpoint - Meihua Biotechnology is advancing steadily in the synthetic biology sector through diversified expansion and deepening development, highlighted by its recent acquisition of assets from Kyowa Hakko Bio, which will enhance its amino acid product lines and operational capabilities [1][2]. Group 1: Acquisition Details - The acquisition agreement between Meihua Biotechnology and Kyowa Hakko Bio is set to be completed by July 1, 2025, with a final transaction value of approximately 16.8 billion yen, equivalent to about 833 million yuan [1]. - The cash reserves of the target assets are estimated at around 11.3 billion yen, or approximately 560 million yuan, as of June 30, 2025 [1]. Group 2: Product and Market Expansion - Post-acquisition, the company will introduce various new amino acids and fermentation strains, including arginine, histidine, serine, citrulline, ornithine, and hydroxyproline, along with patents related to these amino acids [2]. - The transaction will enable the company to extend its industrial chain, enhancing its fermentation and refinement capabilities for high-value pharmaceutical-grade amino acids [2]. Group 3: Strategic Positioning - Meihua Biotechnology aims to implement its overseas development strategy through this acquisition, gaining multiple domestic and international production entities [2]. - The company will also acquire the ability to produce three types of HMO products through a precision fermentation platform, along with the associated intellectual property rights [2]. Group 4: Industry Background - Kyowa Hakko Bio has a long-standing reputation in the global synthetic biology field, with over 70 years of technological expertise and numerous patents in amino acid and HMO product development [3]. - The company has successfully commercialized various amino acids and HMO products, including 2'-fucosyllactose, 3'-sialyllactose, and 6'-sialyllactose [3]. Group 5: Financial Performance - Meihua Biotechnology reported a revenue of 25.069 billion yuan and a net profit of 2.74 billion yuan for 2024, with a significant year-on-year growth of 35.52% in net profit for the first quarter of 2025 [3].

Core Viewpoint - The fourth Synthetic Biology and Green Bio-Manufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on industrial ecological development and the transfer of scientific and technological achievements [1]. Group 1: Conference Overview - SynBioCon 2025 is organized by DT New Materials and supported by various academic and industrial organizations, aiming to facilitate over 1,000 connections between research institutions and startup projects [1]. - The conference will feature a special event showcasing 100 innovative achievements in synthetic biology manufacturing, promoting efficient technology transfer [1][10]. Group 2: Featured Project - The project "Biological Synthesis of L-Piperidine Carboxylic Acid" from Chongqing University focuses on producing L-PA, a crucial non-protein amino acid used in pharmaceuticals [6]. - The first-generation E. coli cell factory achieved a yield of approximately 52.68 g/L with a conversion rate of 90% and a productivity of 2.52 g/L-h, which is considered world-leading [6]. - The second-generation strain using yeast improved the yield to 75.54 g/L and has three core invention patents authorized [6][9]. Group 3: Technical Advantages - The engineered strain has over 90% stability and higher utilization of lysine due to pathway knockout and promoter optimization [8]. - The process benefits from shorter reaction times, lower temperatures to prevent contamination, and 100% optical purity of the product [8]. - The cost-effectiveness of the technology route contributes to high economic benefits [8]. Group 4: Intellectual Property and Collaboration - The project has three authorized core invention patents and offers collaboration opportunities through project partnerships, technology transfers, and joint laboratories [9]. Group 5: Conference Themes - The conference will explore the "1+4" theme, focusing on AI and bio-manufacturing, with applications in green chemicals, new materials, future food, future agriculture, and beauty raw materials [12]. - It aims to discuss the trends in bio-manufacturing during the 14th Five-Year Plan and identify innovative technologies and products that will sustain the industry's vitality [12]. Group 6: Service Platform - A global service platform for bio-based and bio-manufacturing industries is available at www.bio-basedlink.net [15].