中概股盘初大涨。 当地时间12月4日晚间，美股三大指数集体高开，随后震荡走低，三大股指一度纷纷转跌，小幅探底后震荡回升。截至发稿，道指涨0.04%，标普500指数跌0.01%， 纳指跌0.1%。 | 代码 | 名称 | 现价 | 涨跌 | 涨跌幅 | | --- | --- | --- | --- | --- | | DJI | 道琼斯工业平均 | 47899.83 | 16.93 | 0.04% | | IXIC | 纳斯达克指数 | 23429.61 | -24.48 | -0.10% | | SPX | 标普500 | 6849.21 | -0.51 | -0.01% | 经济数据方面，美国上周失业救济申请人数创下 2022 年 9 月以来的最低水平，截至11月29日当周（含感恩节假期），初请失业金人数减少2.7万，至19.1万人，预估 为22万人，前值为21.6万人。 芝商所美联储观察工具最新数据显示，市场对下周三降息的定价概率较昨日（90%）小幅下降，但仍有87%，远高于几周前水平。目前，华尔街普遍认为美联储将 在年内最后一次议息会议上降息25个基点。 个股方面，Meta盘初一度涨超5%，截至发稿涨 ...

Core Viewpoint - The number of billionaires globally is expected to reach a new high by 2025, driven by soaring valuations of technology companies and rising global stock markets [2][4]. Group 1: Billionaire Statistics - Currently, there are approximately 2,900 billionaires worldwide, controlling a total wealth of $15.8 trillion, up from about 2,700 billionaires and nearly $14 trillion a year ago [4]. - An estimated 287 new billionaires are expected to emerge by 2025, marking the second-highest increase since 2015, only behind the surge in 2021 [4]. - The report indicates that the growth of the billionaire population is accelerating and includes both entrepreneurs and heirs [4]. Group 2: Wealth Transfer - Among the new billionaires, 91 are heirs who collectively inherited assets worth $298 billion, including 15 members from two major German pharmaceutical families [5]. - The trend of large-scale intergenerational wealth transfer has been ongoing for over a decade and is now becoming a reality [5]. - Most inherited wealth is expected to first transfer to spouses, typically wives, before being passed on to the next generation [5]. Group 3: Investment Trends - UBS predicts that most wealth transfers will occur in the United States, followed by India, France, Germany, and Switzerland [6]. - A report from Altrata also indicates a historical high in the number of billionaires, estimating 3,508 billionaires with a combined wealth of $13.4 trillion, with about one-third from the U.S. [6]. - Interest in North America as a short-term investment destination has decreased from 81% to 63%, while interest in Western Europe, Greater China, and other Asia-Pacific regions has increased [6]. Group 4: Concerns and Preferences - Asian billionaires are primarily concerned about tariffs, while U.S. billionaires are more focused on inflation and geopolitical risks [7]. - Preferred destinations for billionaires include Switzerland, the UAE, the U.S., and Singapore [7]. - A recent Swiss vote rejected a proposal for a 50% inheritance tax on super-rich individuals, with opponents fearing it could lead to an exodus of wealthy individuals [7].

Group 1 - Hainan Junkai Biotechnology Co., Ltd. has been established with a registered capital of 1 million RMB [1] - The legal representative of the company is Wu Shenglian [1] - The company's business scope includes various services such as occupational health technology services, technical services, ecological environment material manufacturing, and sales [1] Group 2 - The company is involved in the research and development of bio-organic fertilizers and the sale of fertilizers and disinfectants [1] - It also provides environmental emergency treatment services and water pollution prevention services [1] - The company is engaged in comprehensive utilization of agricultural and forestry waste and urban greening management [1]

天眼查App显示，近日，海南省道方生物科技有限公司成立，法定代表人为杨芳芳，注册资本100万人 民币，经营范围为一般经营项目：生物基材料制造；生物基材料销售；新材料技术推广服务；技术服 务、技术开发、技术咨询、技术交流、技术转让、技术推广；节能管理服务；化工产品销售（不含许可 类化工产品）；化工产品生产（不含许可类化工产品）；专用化学产品销售（不含危险化学品）；炼 油、化工生产专用设备制造；新型催化材料及助剂销售；互联网销售（除销售需要许可的商品）；石油 制品销售（不含危险化学品）；第一类医疗器械生产；第一类医疗器械销售；美甲服务；化妆品批发； 化妆品零售；美发饰品销售；健康咨询服务（不含诊疗服务）；远程健康管理服务；日用化学产品销 售；护理机构服务（不含医疗服务）；养老服务；中医养生保健服务（非医疗）；太阳能发电技术服 务；太阳能热利用装备销售（经营范围中的一般经营项目依法自主开展经营活动，通过国家企业信用信 息公示系统（海南）向社会公示）。 ...

天眼查App显示，近日，弥勒市云芝鹿生物科技有限公司成立，法定代表人为卢万芝，注册资本200万 人民币，经营范围为许可项目：种畜禽经营；牲畜饲养；动物饲养；食品销售；食品互联网销售；食品 生产；酒制品生产；酒类经营。（依法须经批准的项目，经相关部门批准后方可开展经营活动，具体经 营项目以相关部门批准文件或许可证件为准）一般项目：牲畜销售；畜禽收购；食品互联网销售（仅销 售预包装食品）；地产中草药（不含中药饮片）购销；技术服务、技术开发、技术咨询、技术交流、技 术转让、技术推广；生物饲料研发；饲料原料销售；农业科学研究和试验发展；食用农产品零售；食用 农产品批发；农副产品销售；食用农产品初加工；货物进出口；技术进出口；中草药种植；中草药收 购。（除依法须经批准的项目外，凭营业执照依法自主开展经营活动）。 ...

根据《上市公司股份回购规则》（2025年修订）、《上海证券交易所上市公司自律监管指引第7号一一 回购股份》（2025年3月修订）等相关规定，现将公司首次回购股份情况公告如下： 2025年12月3日，公司通过上海证券交易所交易系统以集中竞价交易方式首次回购公司股份111,121股， 占公司总股本407,807,559股的比例为0.03%，回购成交的最高价为27元/股，最低价为26.8元/股，支付的 资金总额为人民币2,990,977.1元（不含交易费用）。本次回购股份符合法律法规及公司回购股份方案的 规定。 三、其他事项 登录新浪财经APP 搜索【信披】查看更多考评等级 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或者重大遗漏，并对其内容 的真实性、准确性和完整性承担法律责任。 重要内容提示： ■ 一、回购股份的基本情况 2025年10月30日，深圳微芯生物科技股份有限公司（以下简称"公司"）召开第三届董事会第十七次会 议，审议通过了《关于以集中竞价交易方式回购公司股份方案的议案》。同意公司使用不低于人民币 1,000万元（含），不超过人民币1,500万元（含）的自有资金和股份回购专项贷款 ...

Core Viewpoint - The approval of two supplemental new drug applications for Selinexor (希维奥) by the Hong Kong Department of Health marks a significant expansion for the company in the Hong Kong market, enhancing its competitiveness in the biopharmaceutical industry [1] Group 1: Company Developments - The stock price of Dechra Pharmaceuticals-B (德琪医药-B) increased by approximately 6%, reaching HKD 4.34, with a trading volume of HKD 9.4944 million [1] - The approved applications are for the treatment of multiple myeloma (in combination with bortezomib and dexamethasone for adult patients who have received at least one prior therapy) and relapsed or refractory diffuse large B-cell lymphoma (as a monotherapy for adults who have undergone at least two lines of systemic therapy and are not eligible for hematopoietic stem cell transplantation) [1] Group 2: Industry Implications - The approval signifies the company's ongoing enhancement in research and market promotion capabilities within the biopharmaceutical sector [1] - The introduction of Selinexor is expected to meet the treatment needs for relevant diseases in the Hong Kong market, thereby improving the company's competitive position in the biotechnology industry [1]

近日，圣湘生物举办第三季度业绩说明会，在回答投资者关注的基因测序仪项目相关进展时，圣湘生物 董事长、总经理戴立忠表示，在基因测序领域，公司技术平台取得进一步突破，SansureSeq1000（高通 量）、FASTASeq300Dx（桌面级）及FASTASeqS（快速版）三款测序仪形成了较为完整的产品矩阵， 构建了"仪器+试剂+数据"的一体化布局。同时，创新推出的一步法呼吸道病原靶向基因检测、生殖道 病原微生物靶向基因检测、泛感染靶向基因检测等产品已广泛辐射全国多家客户，公司前三季度测序业 务实现同比增长约150%，展现出强劲的增长势头。 戴立忠提到，今年以来，公司拟参与设立常州灵仲创业投资合伙企业、湖南金芙蓉圣湘生物基金等，将 投资于包括AI医疗应用领域及创新药械等医疗行业技术领先、潜在市场空间大的企业。圣维荣泉、维 特力新等基金合伙人均为具有多年投资专业经验、丰富行业资源、成熟管理模式的专业投资机构，借助 其资本市场资源、管理经验和平台优势，结合圣湘生物在行业内多年的专业知识和产业经验，可有效整 合各方优势资源，进一步探索产业与资本赋能良性互动的多元化发展模式，打造共创、共进、共享、共 赢的行业新生态。 此 ...

Core Viewpoint - Morgan Stanley's 2026 outlook for China's economy and stock market indicates a significant shift in global investors' perception, moving from a market lacking clear growth potential to one rich in growth opportunities, particularly in sectors like AI, new consumption, automation, and biotechnology [1][2]. Group 1: Foreign Investment Trends - Foreign investment sentiment towards the Chinese market is improving, with expectations for continued inflows in 2026 following a substantial valuation recovery in 2025 [2]. - The MSCI China Index has shown significant valuation recovery, marking a milestone for A-shares and Hong Kong stocks, leading to a renewed interest from global investors [2]. - Passive funds have seen a notable increase in inflows, while active funds remain cautious, with less than 5% of their global investment capacity allocated to Chinese stocks [3]. Group 2: Positive Economic Changes - Three positive changes in the Chinese economy have emerged since the "9·24" policy shift: 1. Enhanced policy responsiveness, with a focus on development and flexible adjustments [4]. 2. Resilience and innovation among Chinese enterprises, showcasing advancements in AI, smart vehicles, and biopharmaceuticals [4]. 3. A shift in global investor focus from dollar assets to diversified allocations, with a growing interest in China's tech innovations [4]. Group 3: Policy and Infrastructure Investment - The 2026 fiscal policy is expected to prioritize infrastructure investments in new areas such as underground pipeline renovations and green transition projects, driven by carbon reduction goals [5]. - Increased support for consumption through measures like birth subsidies and social security enhancements reflects a flexible and rich policy toolbox [5]. Group 4: Market Dynamics and Investment Strategy - The market's driving logic is set to change in 2026, with a completed valuation recovery and a stable, reasonable valuation level that can attract new capital [7]. - The anticipated easing of global liquidity, including three expected interest rate cuts by the Federal Reserve in the first half of 2026, will support stock assets [7]. - Investment strategies should focus on high-growth sectors aligned with China's long-term development, such as high-end manufacturing, AI, and biotechnology, while also including quality dividend-paying sectors like insurance [7].

以下文章来源于赛业生物订阅号 ，作者小赛 赛业生物订阅号 . 分享生命科学领域的前沿资讯、解读行业动态、讲解实用的学科知识、实验方法和技巧。 师姐 你的flox鼠和Cre鼠是同一个品系吗？实验后期很容易出现好几代交配完，才发现背 景不纯、Cre还泄露了的情况。 类似的对话，也许时常出现在你的身边，从课题启动到获得可靠数据，基因敲入模型的构建之路往往布满荆 棘： ❓ 传统ES打靶结合多代育种流程漫长，如何将模型交付周期缩短一半以上？ 如此种种，让宝贵的科研时间在反复验证中悄然流逝。 新一期线上课程 「基因敲入（KI）模型构建策略及应用案例分析」 将深入剖析。 课程时间： 12月9日（周二）晚7点 讲师： 赛业生物生产中心ES部经理李晓亮、生产中心分子部门经理王康 师妹 完蛋，我的敲入小鼠和预期的表型对不上，但我明明是按Protocol做的…… 通过这节课你可以学到什么？ ❓ 如何避免Cre工具鼠的泄露表达、重组效率低等问题对表型数据造成干扰？ ❓ 面对复杂条件性模型，如何在保证高成功率的同时，有效控制项目成本？ 1 KI、CKI模型分别对应的设计逻辑、适用场景及其在基因功能研究中的价值 2 新一代ES打靶技术如 ...