公司研究 证 券 研 究 报 告 苑东生物（688513）深度研究报告 强推（维持） 体系整合，上海超阳打造差异化创新竞争力 目标价：87.6 元 [ReportFinancialIndex] 主要财务指标 | | 2024A | 2025E | | 2026E | 2027E | | --- | --- | --- | --- | --- | --- | | 营业总收入(百万) | 1,350 | 1,376 | | 1,567 | 1,933 | | 同比增速(%) | 20.8% | 2.0% | | 13.8% | 23.4% | | 归母净利润(百万) | 238 | 277 | | 316 | 388 | | 同比增速(%) | 5.1% | 16.2% | | 14.0% | 22.9% | | 每股盈利(元) | 1.35 | 1.57 | | 1.79 | 2.20 | | 市盈率(倍) | 44 | 38 | | 34 | 27 | | 市净率(倍) | 3.9 | 3.6 | | 3.4 | 3.1 | | 资料来源：公司公告， | 华创证券预测 | 注：股价为 2025 | 年 12 ...

Core Viewpoint - Yuan Dong Bio is focusing on innovation-driven development in the biopharmaceutical sector, with a comprehensive industrial layout in chemical raw materials, high-end chemical drugs, and biological drugs [1] Summary by Relevant Sections Innovation Drug Development - The company has over 80 ongoing research projects, with innovative drug projects accounting for 24.4% of the total, including small molecule new drugs, biological drugs, and modified new drugs [1] - In the small molecule new drug category, the drug "Yoglitin Tablets" has achieved the expected goals in its Phase III clinical trial, while EP-0108 capsules, EP-0146 tablets, and EP-0186 tablets have received clinical trial approvals [1] - In the biological drug sector, the anesthetic and analgesic drug EP-9001A monoclonal antibody has completed Phase Ib clinical trials, and the ADC innovative drug YLSH003 has submitted an IND and received clinical approval [1] - Several modified new drugs, such as oral solution of chloral hydrate and extended-release oxycodone tablets, have been submitted for production, with multiple distinctive modified new drugs entering clinical stages [1] Strategic Investments and Collaborations - The company is actively tracking global cutting-edge technologies and accelerating its innovation transformation through strategic investments, external introductions, and collaborative development [1] - Following the acquisition of shares in Shanghai Chaoyang, the company's indirect shareholding increased from 11.36% to 30.68%, and it plans to further increase its stake to achieve controlling interest, raising its indirect ownership to 51.48% [1] - This strategic control over Shanghai Chaoyang will enhance the company's pipeline in frontier technology areas such as molecular glue, PROTAC (proteolysis-targeting chimeras), and DAC (drug-antibody conjugates), strengthening its R&D capabilities in innovative drugs [1]

Investment Rating - The report maintains an "Accumulate" rating for the company [4][10] Core Views - The company's performance is under short-term pressure due to the implementation of centralized procurement, with a revenue of 654 million yuan in the first half of 2025, down 2.3%, and a net profit of 137 million yuan, down 6.8% [1][4] - The company is advancing its innovation transformation through self-research and strategic investments, with multiple new drugs making clinical progress [2][3] Financial Performance Summary - In the first half of 2025, the company reported a revenue of 654 million yuan, a decrease of 2.3%, and a net profit of 137 million yuan, a decrease of 6.8%. The gross margin was 75.81%, down 1.9 percentage points, and the net margin was 20.87%, down 1.0 percentage points [1][4] - For Q2 2025, revenue was 349 million yuan, down 1.7%, while net profit increased by 7.0% to 76 million yuan [1] - The company’s expense ratios included a sales expense ratio of 31.64% (down 3.7 percentage points), a management expense ratio of 6.91% (up 0.4 percentage points), and a research and development expense ratio of 19.79% (up 3.5 percentage points) [1] Innovation and Strategic Investment Summary - The company has made progress in its self-research pipeline, with several new drugs receiving clinical approvals, including small molecule drugs EP-0108, EP-0146, and EP-0186, as well as the monoclonal antibody EP-9001A completing phase 1b clinical trials [2] - Strategic investments are accelerating the company's innovation transformation, including an increase in equity investment in Shanghai Chaoyang Pharmaceutical to 30.68%, focusing on oncology and autoimmune areas [2] Profit Forecast - The company is expected to achieve revenues of 1.501 billion yuan, 1.795 billion yuan, and 2.202 billion yuan for 2025, 2026, and 2027 respectively, with year-on-year growth rates of 11.2%, 19.6%, and 22.7% [3] - The forecasted net profit for the same years is 282 million yuan, 345 million yuan, and 431 million yuan, with growth rates of 18.2%, 22.5%, and 24.8% respectively [3]

Group 1: Yuan Dong Bio - In the first half of 2025, Yuan Dong Bio achieved revenue of 654 million yuan, a year-on-year decrease of 2.25% [1] - The net profit attributable to shareholders was 137 million yuan, down 6.77% year-on-year, but excluding stock incentive costs, it showed a slight increase of 0.28% [1] - R&D investment was approximately 133 million yuan, accounting for 20.25% of revenue, with new drug R&D investment amounting to 44.83 million yuan, representing 33.83% of total R&D expenditure [1] - The company is responding to centralized procurement policies by enhancing innovation, deepening transformation, and improving operational efficiency across the value chain [1] - The ADC innovative drug YLSH003 has completed preclinical research and IND application, while HP-001 is undergoing Phase I clinical trials with overall safety deemed good [1] Group 2: Fei Ling Ke Si - In the first half of 2025, Fei Ling Ke Si focused on its core business while actively expanding new products and clients [2] - The top five customers accounted for 96.77% of the company's revenue, with data center switch sales increasing by 67% year-on-year [2] - R&D investment was 71.89 million yuan, making up 9.96% of revenue, and the company has completed multiple product iterations and upgrades [2] - The overseas market generated sales revenue of 15.18 million yuan, primarily through collaborations with clients in Japan and South Korea [2] - The Zhejiang Haining production base achieved revenue of 171 million yuan with a net profit of 2.86 million yuan [2]

Group 1 - The core viewpoint of the news is that KaiFeng Investment has conducted research on YuanDong Bio, revealing a decline in revenue and net profit for the first half of 2025, alongside ongoing clinical trials for new drugs [1] - YuanDong Bio achieved operating revenue of 654 million yuan, a year-on-year decrease of 2.25%, and a net profit attributable to shareholders of 137 million yuan, down 6.77% year-on-year, although excluding stock incentive costs, there was a slight increase of 0.28% [1] - The company's R&D investment was approximately 133 million yuan, accounting for 20.25% of operating revenue, with new drug R&D expenditures amounting to 44.83 million yuan, representing 33.83% of total R&D investment [1] Group 2 - The international business of YuanDong Bio includes APIs and formulations, with multiple products either registered or submitted for registration [1] - The API and CDMO segment generated operating revenue of 87 million yuan, reflecting a year-on-year growth of 3.17%, although the growth rate has slowed [1] - YuanDong Bio is responding to the impact of centralized procurement policies by enhancing innovation, deepening transformation, and improving operational efficiency across the entire value chain [1] Group 3 - The HP-001 drug is currently undergoing Phase I clinical trials, showing overall good safety [1] - The ADC innovative drug YLSH003 has completed preclinical research and IND submission [1] - The extended-release acetaminophen and morphine sulfate naloxone capsules have been submitted for production and are currently under review [1]

Group 1: Yuan Dong Bio - In the first half of 2025, Yuan Dong Bio achieved revenue of 654 million, a year-on-year decrease of 2.25%, and a net profit attributable to shareholders of 137 million, down 6.77%. Excluding stock incentive expenses, net profit increased by 0.28% [1] - R&D investment was approximately 133 million, accounting for 20.25% of revenue, with new drug R&D investment amounting to 44.83 million, representing 33.83% of total R&D expenditure [1] - The company is responding to centralized procurement policies by enhancing innovation, deepening transformation, and improving operational efficiency across the value chain [1] - The ADC innovative drug YLSH003 has completed preclinical research and IND application, while HP-001 is undergoing Phase I clinical trials with overall safety deemed good [1] Group 2: Shan Jin International - Shan Jin International reported a decrease in gold production in the first half of 2023 compared to the same period last year, but is implementing various measures to recover production in the second half [2] - The trading company experienced losses primarily due to the net profit from the consolidation of overseas entities [2] - The company has strategic plans for 2023, focusing on existing mine management and resource project development to achieve its goals [2] - The Osino project is expected to commence production in the first half of 2027, with an average annual gold output of 5 tons, contributing significantly to future production growth [2] - The dividend policy remains stable, with the main gold-producing mines expected to contribute 95.87% to the company's net profit in 2024 [2]

Group 1 - The core viewpoint of the news is that Chenyang Investment has conducted research on a listed company, Yuandong Bio, revealing its financial performance and strategic initiatives in response to market challenges [1] Group 2 - Yuandong Bio reported a revenue of 654 million yuan for the first half of 2025, a year-on-year decrease of 2.25%, and a net profit attributable to shareholders of 137 million yuan, down 6.77% year-on-year, although excluding stock incentive costs, it showed a slight increase of 0.28% [1] - The company's R&D investment was approximately 133 million yuan, accounting for 20.25% of its revenue, with new drug development expenditures amounting to 44.83 million yuan, representing 33.83% of total R&D spending [1] - The international business includes APIs and formulations, with multiple products either registered or submitted for registration [1] - The API and CDMO segment achieved a revenue of 87 million yuan, reflecting a year-on-year growth of 3.17%, although the growth rate has slowed [1] - Yuandong Bio is addressing the impact of centralized procurement policies through innovation-driven strategies, deepening transformation, and enhancing operational efficiency across the value chain [1] - The clinical trial for HP-001 is currently in Phase I, showing overall good safety, while the ADC innovative drug YLSH003 has completed preclinical research and IND submission [1] - The company has submitted production applications for Acetaminophen and Oxycodone sustained-release tablets and Morphine Sulfate and Naloxone sustained-release capsules, which are currently under review [1]

Group 1: Yuan Dong Biological - In the first half of 2025, Yuan Dong Biological achieved revenue of 654 million yuan, a year-on-year decrease of 2.25% [1] - The net profit attributable to the parent company was 137 million yuan, down 6.77% year-on-year, but excluding stock incentive costs, it showed a slight increase of 0.28% [1] - R&D investment was approximately 133 million yuan, accounting for 20.25% of revenue, with new drug R&D investment amounting to 44.83 million yuan, representing 33.83% of total R&D expenditure [1] - The company is responding to the impact of centralized procurement policies by enhancing innovation, deepening transformation, and improving operational efficiency across the value chain [1] - The ADC innovative drug YLSH003 has completed preclinical research and IND application, while HP-001 is undergoing Phase I clinical trials with overall safety reported as good [1] Group 2: Yinxi Technology - Yinxi Technology's business includes modified plastics and smart lighting, with significant growth in the modified plastics segment and a favorable gross margin [2] - The company has seen a continuous increase in drone orders, although customer details are confidential [2] - The PPO business, which includes injection-molded modified plastics and electronic chemicals, has passed downstream customer certification, with gradually increasing but still low production capacity [2] - The company has no plans for low-altitude economy asset injection, and recent share reductions are part of normal information disclosure, expected not to adversely affect stock prices [2] - Yinxi Technology collaborates with companies incubated by Professor Li Zexiang, producing modified environmentally friendly flame retardants and other additives primarily for external sales [2] Group 3: Hongcheng Investment Overview - Hongcheng Investment was founded in April 2015 by Zhang Tao and several colleagues, with complementary work experience and knowledge structures [3] - The long-term vision of the company is to create an attractive platform for excellent fund managers and generate stable long-term returns for public investors [3] - The company culture emphasizes openness, equality, sharing, and inclusiveness [3]

Group 1 - The core viewpoint of the news is that Yuandong Biological has reported a decline in revenue and net profit for the first half of 2025, while also highlighting its ongoing research and development efforts and international business expansion [1] Group 2 - Yuandong Biological achieved operating revenue of 654 million yuan, a year-on-year decrease of 2.25%, and a net profit attributable to shareholders of 137 million yuan, down 6.77% year-on-year, although excluding stock incentive costs, there was a slight increase of 0.28% [1] - The company's R&D investment was approximately 133 million yuan, accounting for 20.25% of operating revenue, with new drug development expenditures amounting to 44.83 million yuan, representing 33.83% of total R&D investment [1] - The revenue from the API and CDMO segment was 87 million yuan, showing a year-on-year growth of 3.17%, although the growth rate has slowed [1] - Yuandong Biological is responding to the impact of centralized procurement policies by enhancing innovation, deepening transformation, and improving operational efficiency across the entire value chain [1] - The clinical trial for HP-001 is currently in Phase I, showing overall good safety, while the ADC innovative drug YLSH003 has completed preclinical research and IND submission [1] - The company has submitted production applications for Acetaminophen and Oxycodone sustained-release tablets and Morphine Sulfate and Naloxone sustained-release capsules, which are currently under review [1]

Group 1 - The report highlights that the "anti-involution" trend is driving a super cycle in commodities, particularly benefiting upstream resources and midstream materials, with the true focus being on the midstream sector [2][14] - The report suggests that the "anti-involution" phenomenon is a precursor to debt reduction, indicating that future demand-side policies will be crucial following the recent supply-side adjustments [3][15] - The ROIC-WACC metric is identified as a key indicator for measuring "involution," with industries like coking coal and photovoltaic equipment being classified as "true involution" sectors that are poised for growth [4][16] Group 2 - The report recommends a stock portfolio for August 2025, including companies such as Dingjie Zhizhi (computing), Yuandong Biological (pharmaceuticals), and BYD (automotive), among others [6][11] - The report emphasizes the importance of monitoring demand-side policy implementation and potential liquidity pressures from overseas markets [5][13] - The report notes that the strong exchange rate is expected to support continued export strength, which may exceed market expectations [5][13]