Core Viewpoint - Jichuan Pharmaceutical (600566) is focusing on the commercialization of a new drug for allergic rhinitis, PG-011 nasal spray, through a partnership with Beijing Puqi Pharmaceutical Technology Co., Ltd. [1][3] Group 1: Commercialization Agreement - Jichuan Pharmaceutical's subsidiary, Jichuan Pharmaceutical Group Co., Ltd., has signed an exclusive commercialization agreement with Puqi Pharmaceutical, granting Jichuan the rights to commercialize PG-011 in China, including mainland, Hong Kong, Macau, and Taiwan [1][3] - The maximum payment for this exclusive commercialization right is capped at 100 million yuan (including tax) [1][3] Group 2: Product Details - PG-011 is a self-developed JAK1/2 inhibitor aimed at treating allergic rhinitis and is expected to be the world's first JAK inhibitor nasal spray [3] - The clinical trial application for PG-011 was approved by the National Medical Products Administration (NMPA) on August 2, 2023, and it is currently in the clinical phase III stage [3] Group 3: Financial Implications for Puqi Pharmaceutical - Puqi Pharmaceutical is currently not profitable, with projected net revenues of 11.22 million yuan and 1.158 million yuan for 2024 and the first three quarters of 2025, respectively, alongside losses of 178 million yuan and 125 million yuan during the same periods [3][4] - The commercialization agreement is expected to provide significant revenue for Puqi Pharmaceutical, which has high R&D expenditures, accounting for 78.2% and 77.7% of total operating expenses in 2024 and the first three quarters of 2025, respectively [4] Group 4: Additional Agreements - Following the agreement with Puqi Pharmaceutical, Jichuan Pharmaceutical also announced a separate exclusive commercialization rights agreement with Jiangsu Jiyuan Pharmaceutical Co., Ltd. and others for the drug Inusimab, with a payment of 80 million yuan (including tax) and potential milestone payments of up to 10 million yuan [4][5] Group 5: Financial Performance of Jichuan Pharmaceutical - Jichuan Pharmaceutical reported a revenue of approximately 3.932 billion yuan for the first three quarters of 2025, a year-on-year decrease of 32.27%, and a net profit of about 1.022 billion yuan, down 46.27% [5] - The company has experienced a decline in both revenue and net profit since 2024, with revenues of approximately 8.017 billion yuan and net profits of about 2.532 billion yuan, reflecting decreases of 16.96% and 10.32%, respectively [5]

Core Viewpoint - The securities industry is undergoing a significant restructuring, with multiple firms announcing the closure of branch offices to optimize their operations and enhance online service capabilities [2][3][4]. Group 1: Branch Office Closures - On February 2, Changcheng Securities announced the closure of its Zhengzhou Longhai Road branch, following similar announcements from other firms like Zhongyou Securities and Xibu Securities [3]. - The trend of closing branch offices is not isolated; in 2025, some firms closed over 10 branches, indicating a broader strategy to optimize the national network of offices [3][4]. - The reasons for these closures are consistent across firms, focusing on "optimizing branch layouts" and "improving operational efficiency" [4]. Group 2: Online Business Development - Despite the reduction in physical branches, firms are not scaling back their service capabilities; instead, they are enhancing their online business structures [5]. - The establishment of internet securities subsidiaries, such as China Galaxy Securities' Beijing Internet Securities subsidiary, marks a shift towards digital transformation in the industry [5]. - These internet and digital subsidiaries are designed to support online customer service, trading, and digital operations, distinguishing them from traditional branch offices [5][6]. Group 3: Impact on Customer Services - The closure of branch offices is stated to have no adverse effects on customer transactions or asset security, with services continuing through mobile apps and online platforms [6]. - The integration of online and offline resources is expected to enhance overall competitiveness in the securities industry, allowing firms to allocate resources more effectively [6].

2026/02/04 04:02 [ 农历腊月十七 ] (甘四节气) 春风轻拂寒意散 · 万物复苏迎春来 京日报客户端 来源：北 ...

该项目建设在技术创新、施工组织和产业带动等方面取得一系列突破性成果，多项指标刷新当地铁路建 设纪录。项目建设中，中国团队坚持技术引领、标准先行，首次完成32.5吨大轴重货车与160公里/小时 客车共线运营的预应力混凝土轨枕设计，顺利通过EN13230系列标准检验认证，实现了拥有100%自主 知识产权的中国铁路技术从设计、制造到应用的全链条输出。 据悉，阿尔及利亚西部铁路矿业线项目是当地重要基础设施工程之一，更被视为推动阿尔及利亚国家经 济发展的重要发展动脉。该项目可实现每年运输5000万吨铁矿石，同时配套运输来贝沙尔省工业区的 2500万吨成品和半成品，实现该国铁路运输能力升级。该项目在未来的运维中，将创造不少于3000个就 业岗位，推动当地就业，带动经济发展。 来源：北京日报客户端 当地时间2月1日，阿尔及利亚西部铁路矿业线项目全线正式通车。该项目由中国铁建承建，是中国企业 在非洲建设的首条沙漠重载铁路。 该项目全长950公里，中国铁建与当地国有企业承建了其中575公里，是中企在阿最大的基建工程。据介 绍，在最高温达50余摄氏度的撒哈拉沙漠中，8000余名中阿建设者仅用24个月就完成了575公里铁路建 设。 ...

按照北京城市总体规划，平原新城是指顺义、大兴、亦庄、昌平、房山的新城及地区，是首都面向区域 协同发展的重要战略门户，是承接中心城区适宜功能、服务保障首都功能的重点地区，也是构建现代化 首都都市圈的重要一环。 日前，由北京市、天津市、河北省联合编制的《现代化首都都市圈空间协同规划（2023—2035年）》 （以下简称《规划》）发布，《规划》提出，全面提升平原新城综合承载能力。实施战略赋能，依托资 源禀赋，抢抓发展先机，打造特色鲜明、有影响力的新城名片。实施要素赋能，围绕产业链统筹布局人 才链，营造良好人才生态和发展环境，加大人才、资金、土地等要素倾斜支持，提升资源配置能力。实 施功能赋能，打造便捷高效的交通通道，加快布局优质教育、医疗、养老、托育等公共服务资源。实施 政策赋能，加强用地功能兼容与建筑复合利用。 为将提升平原新城综合承载能力的部署落到实处，破解各区发展难题，推动政策红利精准释放，2025年 初，北京市政府根据各平原新城特点和实际，"一区一策"批复了各具特色的高质量发展实施方案，进一 步明确了平原新城各区发展定位、发展目标和具体任务。顺义区聚焦国际化水平提升，重点建设临空经 济先行区、产城融合国际新 ...

来源：京报体育 第三节，北汽队长时间处于落后，场面上有些混乱。北汽队叫了暂停，防守上更加强硬，进攻中斯佩尔 曼和杰曼接连打成2+1，三节过后，北汽队62比64落后2分。两队在末节竞争激烈，北汽队在获得领先 后没有再犯上一场的错误，将胜果攥在手中。 CBA第一阶段就此结束，在全部23轮比赛中，北汽队取得14胜9负，整体表现可谓高开低走。开局阶段 的七连胜，让球队一度领跑积分榜。然而，自此之后球队状态起伏不定，整体发挥不尽如人意。造成这 种局面有球员伤病不断的客观因素，也暴露出球队在技战术方面存在的问题。自从进入2026年以来，北 汽队还没有取得过连胜。 CBA进入休赛期，没有俱乐部杯任务的北汽队将有一个多月的调整时间，再进行比赛要到3月11日了。 定下高目标的北汽队要针对现存问题，找方法、养伤病、调状态，在后续比赛中提升名次，力争在常规 赛取得一个理想的成绩，为季后赛打下良好的基础。 2月3日，在CBA常规赛第23轮比赛中，北京北汽队经过一场苦战，以85比77战胜福建队，用一场胜利 结束本赛季第一阶段的比赛。 本场比赛之前，北汽队接连输给了天津队和青岛队，遭遇两连败，这是球队本赛季第二次出现连败的情 况。本轮面 ...

【#周生生回应足金挂坠被检测出铁银钯#】#周生生称足金挂坠符合国家标准#2月3日，@周生生 发布 情况说明：针对顾客反馈的相关情况，周生生高度重视，第一时间复核了当时出厂批次的破坏性检测报 告，报告显示该批次货品质量完全符合国家相关标准。同时，今日2月3日，周生生已将同批次同款福袋 送检至国家珠宝玉石首饰检验集团有限公司（NGTC)，采用X射线荧光光谱法(XRF)进行检测，该福袋 货品的检测结论为足金饰品(报告编号:P-ZSSA2121621)。NGTC对该货品随机选取3个检测点，检测所得 金含量结果依次为99.99%、99.99%、99.98%。 此前有媒体报道，近日，有消费者向央广网啄木鸟消费 者投诉 【下载黑猫投诉客户端】平台反映，她新购买的周生生足金福袋挂坠佩戴一天后即被刮花，并 出现白色痕迹。因对饰品含金量产生怀疑，她将挂坠送检，结果发现不同点位的金含量数据存在差异。 （周生生 央广网） #周生生官方回应# ...

Core Insights - The meeting held on February 3 aimed to strengthen communication between government, banks, and enterprises to ensure funding for key projects in Beijing, supporting investment and economic growth goals for the first quarter and the entire year [1][17]. Group 1: Meeting Overview - The meeting combined in-person and online participation, with approximately 240 attendees, including representatives from various financial institutions and key project units [3]. - The Beijing Development and Reform Commission presented investment strategies and financing needs, while other departments discussed policies to support high-quality development and technological independence [4]. Group 2: Financing Needs and Projects - A total of 165 key financing projects were announced, with a total investment of approximately 2,851 billion and a financing demand of about 763 billion [7]. - The projects are categorized into three types: - Industrial development projects (138 projects) with a total investment of about 1,641 billion and financing needs of approximately 573 billion - Infrastructure projects (10 projects) with a total investment of about 652 billion and financing needs of approximately 71 billion - Livelihood improvement projects (17 projects) with a total investment of about 557 billion and financing needs of approximately 120 billion [7]. Group 3: Financial Service Enhancement - Financial institutions are encouraged to align with the city's economic development priorities, focusing on expanding domestic demand, modernizing the industrial system, regional coordinated development, and improving public services [8][9][10][11][12]. - The meeting emphasized the importance of collaboration between government, banks, and enterprises to enhance service levels and support the real economy [13]. Group 4: Continuous Improvement Initiatives - The meeting outlined plans to improve financing matching services, enhance policy support, and optimize the business environment to facilitate project financing [14][16][17]. - Specific actions include rolling out project lists with financing needs, improving the effectiveness of financing matches, and reducing financing costs for small and micro enterprises [15][16].

Group 1 - The cultural industry in Beijing is projected to achieve a total revenue of 26,738.6 billion yuan by 2025, representing a year-on-year growth of 13.8% [1] - Major cultural enterprises in Beijing are expected to generate an operating income of 26,215.1 billion yuan, with a year-on-year increase of 14.1%, and a total profit of 4,352.3 billion yuan, reflecting a growth of 21.5% [1] - The success of the animated film "Nezha: Birth of the Demon Child," which grossed over 15 billion yuan globally, exemplifies the impact of high-quality content creation on the growth of the cultural industry [1] Group 2 - In 2025, over 60,000 ticketed performances are anticipated in Beijing, attracting more than 14 million attendees, with venues like the Bird's Nest and Huaxi LIVE becoming popular hotspots [2] - The core cultural sectors in Beijing are expected to generate a total revenue of 24,426.1 billion yuan, marking a year-on-year growth of 14.9%, with significant increases in news information services, content creation, creative design services, and cultural dissemination channels [2] - The cultural-related sectors are projected to achieve a total revenue of 2,312.4 billion yuan, with a year-on-year growth of 4.0%, and cultural consumption terminal production revenue is expected to grow by 14.0% [2] Group 3 - The development of new cultural business formats is accelerating, with cultural new economy enterprises in Beijing projected to achieve an operating income of 18,834.9 billion yuan, reflecting a year-on-year growth of 17.2% and accounting for 71.8% of the total operating income of cultural enterprises [3]

Core Viewpoint - The article highlights the comprehensive and innovative services provided during the 2026 Spring Festival travel season in Beijing, aiming to enhance the travel experience for passengers and address their diverse needs [1] Group 1: Service Innovations - Beijing Capital Airport and Daxing Airport have introduced various convenient measures, including professional packaging services for specialty foods and special wristbands for elderly travelers that include QR codes for easy access to rights and guidance [1] - The introduction of a "foreign airline international check-in" service and self-service check-in has reduced average travel time by over 15 minutes, while security check efficiency has improved by 40% with the establishment of "easy security" lanes [1] Group 2: Passenger Flow Management - During the peak travel period, the city will implement measures such as extended subway hours, preferential dispatching for ride-hailing platforms, and public transport guarantees to match capacity with passenger flow effectively [1] - An estimated 39.7 million passengers are expected to travel through the eight major train stations in Beijing during this Spring Festival, marking a significant test for the city's transportation management [1] Group 3: Human-Centric Approach - The services provided reflect a commitment to human-centered management, ensuring that every traveler feels seen and cared for, which enhances the overall experience of returning home or traveling for leisure [1] - The article emphasizes the importance of personalized service in addressing the diverse needs of travelers, showcasing the city's ability to manage the pressures of the Spring Festival effectively while maintaining a warm and welcoming atmosphere [1]