合成生物学与绿色生物制造
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同舟纵横:专注于工业流体领域的分离纯化 | SynBioCon 2025推荐
合成生物学与绿色生物制造· 2025-06-30 14:09
Core Viewpoint - The article highlights the participation of Tongzhou Zongheng in the SynBioCon 2025, focusing on the integration of material separation across various sectors, including membrane material production, process research and development, equipment manufacturing, process design, and technical services [1][20]. Company Overview - Tongzhou Zongheng (Xiamen) Fluid Technology Co., Ltd. specializes in the separation and purification of industrial fluids, operating as a national high-tech enterprise and a specialized small giant enterprise. The company has completed hundreds of engineering projects across various fields such as pharmaceuticals, chemicals, food additives, starch sugars, bio-fermentation, plant extraction, new energy, and environmental protection, establishing a strong industry reputation [6]. Product Introduction - **Ceramic Membrane**: Made from sapphire material, it offers high purity, excellent anti-pollution performance, and long lifespan with ultrafiltration level filtration precision [8]. - **Spiral Membrane**: Features a custom grid design, suitable for various special separation scenarios, resistant to high suspended solids, high temperatures, and high pressures [10]. - **Continuous Chromatography**: Reduces resin usage by 50%-90% compared to traditional fixed-bed chromatography, decreases acid-base salt wastewater generation by 50%-70%, and offers compact equipment design for space-saving and automated control [12]. - **Electrodialysis Membrane**: Used for desalination, concentration, and recovery purification of acids and bases [14]. - **Tubular Membrane**: Utilizes high-performance polymers with permanent hydrophilicity, designed to save membrane replacement costs [16]. - **High-Pressure Concentration System**: Handles high-salinity components with strong anti-fouling properties, achieving pressures up to 120 bar [18]. Event Announcement - The fourth SynBioCon 2025 will be held from August 20-22 in Ningbo, Zhejiang, focusing on the "1+4" theme: AI + Bio-manufacturing, along with four application areas: green chemistry and new materials, future food, future agriculture, and beauty raw materials. The event aims to explore the development trends of the bio-manufacturing industry during the 14th Five-Year Plan and promote the transfer and transformation of scientific achievements, product scaling, and talent acquisition [20].
我国又一合成生物智能研发平台(AI4S)发布!20+单位已合作!
合成生物学与绿色生物制造· 2025-06-30 14:09
Core Viewpoint - The establishment of the AI4S synthetic biology intelligent research platform by Anhui Normal University, University of Science and Technology of China, and Wuhu Yijiang District aims to advance key technologies in synthetic biology, focusing on gene design, enzyme optimization, and biomanufacturing applications in various strategic emerging industries [1][6][10]. Group 1: Platform Overview - The AI4S platform will collaborate with over 20 enterprises and medical institutions, emphasizing breakthroughs in genome design and enzyme molecular modification [1][6]. - The platform integrates AI technology with automated experimental equipment to enhance experimental efficiency and data collection through high-throughput operations [3][8]. Group 2: Research Directions - The platform focuses on six major research areas: gene circuit design, enzyme discovery and optimization, metabolic pathway exploration, synthetic biology big data analysis, artificial cell factory creation, and biopharmaceutical synthesis [1][6]. - It aims to address critical challenges in biomanufacturing, including efficient gene design, experimental automation, data-driven optimization, and industrial-scale production [7][10]. Group 3: Technological Integration - The platform will create an integrated AI simulation and experimental validation system, combining high-performance computing and machine learning with experimental data [3][9]. - It will support virtual screening, experimental validation, and the establishment of cell factory models, enhancing the product development lifecycle [3][10]. Group 4: Industry Landscape - Multiple institutions in China have established similar synthetic biology platforms, including the Shenzhen Institute of Advanced Technology and Peking University, indicating a growing trend in the sector [4][6]. - Companies like BGI, Huaheng Biotechnology, and others are adopting AI and automated fermentation optimization platforms to accelerate product development [11]. Group 5: Future Prospects - With increasing policy support and industry demand, more institutions are expected to enter the field of synthetic biology and AI integration [12]. - The upcoming SynBioCon 2025 conference will focus on AI and biomanufacturing, exploring technological innovations and industry trends [14][16].
川大成果!合成生物“长寿分子” 亚精胺实现量产!
合成生物学与绿色生物制造· 2025-06-30 14:09
Core Viewpoint - The article discusses the innovative production and application of spermidine, a natural polyamine with significant potential in anti-aging and cardiovascular disease prevention, through synthetic biology techniques developed by a research team at Sichuan University [1][2]. Group 1: Spermidine Production Challenges - Spermidine is recognized as a promising bioactive molecule, but its high production costs have hindered large-scale industrial application [1][2]. - Traditional extraction methods yield low purity (only 1% from wheat germ) and are inefficient, while chemical synthesis is costly, leading to market domination by foreign companies [2][3]. Group 2: Technological Innovations - The research team employs machine learning algorithms to simulate yeast metabolic networks, significantly enhancing spermidine synthesis efficiency [3]. - A breakthrough in the discovery of an extracellular secretion mechanism allows spermidine to be actively expelled from cells, reducing energy consumption and improving purity during extraction [4]. Group 3: Industry Collaboration and Education - The collaboration between academia and industry enables students to engage in practical applications, bridging the gap between laboratory research and market needs [4][8]. - The establishment of a project-based learning model in universities aims to cultivate versatile talents for the industry [4][9]. Group 4: Market Potential and Policy Support - Spermidine is positioned to drive multiple billion-dollar industries, with ongoing clinical trials in the pharmaceutical sector and product development in the food industry [6][7]. - Chengdu is emerging as a hub for synthetic biology, with supportive policies from various provinces to facilitate technology transfer and commercialization [7][8]. Group 5: Future Outlook - The global economic impact of synthetic biology is projected to yield $2-4 trillion annually between 2030 and 2040, indicating a significant opportunity for industries leveraging these technologies [6]. - The integration of academic research, industry needs, and supportive policies is expected to enhance the domestic production of critical bioactive substances like spermidine, contributing to public health initiatives [8][9].
生物制造领域 “潜力股” 团队?生物制造青年论坛,报告征集中!8月20-22日宁波
合成生物学与绿色生物制造· 2025-06-30 14:09
生物制造领域有哪些 "潜力股" 团队、技术和产品值 得关注? 为发掘合成生物学和生物制造科研团队创新成果、 促进生物制造领域优秀科研工作者成果交流和产业方对接, 第四届合成生物与绿色生物制造大会 (简称: SynBioCon 2025 ) 同期将举办特色专场——" 生物制造青年论坛 ",于8月20日在浙江宁波举办。 助力行业 15分钟了解一个方向 ,重点阐述研究领域存在的科学问题、解决思路、成果、放大可行性以及未来发展方向。 欢迎高校、科研院所申报分享! 扫码报名,请选择参会形式 报名请选择:青年论坛、科技成果展示 SynBioCon 大会 | 生物制造青年论坛 特色专场 生物制造青年论坛 8月20日,浙江·宁波 02 科技成果展示与对接专场 (同期活动) SynBioCon 2025 将设置 「科技成果展示与对接」专场 (现场展示科技成果推介墙), 公开征集100个从0—1—100的合成生物和生物制造领域创新成果 和项目 ,于现场展示、对接。 欢迎科研院所、企业报名! 往期现场: 03 大会日程 SynBioCon 2 025 8月20-22日,浙江·宁波 01 论坛信息 时 间: 8月20日(周三) 席 ...
上海美藻生物新一代藻类活性提取物首次亮相荣格PCT2025美妆展
合成生物学与绿色生物制造· 2025-06-29 11:18
荣格个人护理 . 以下文章来源于荣格个人护理 ,作者荣格研讨会 MicroZenith@紫球藻提取物 抗皱,紧致,防晒,保湿、抗 氧化、抗菌、抗病毒 我司海洋微藻细胞培养的优势: 个人护理、美容、化妆品、香水、包装等行业专业人士必读,覆盖全球资讯,关注中国市场,荣格工业 传媒旗下《happi China 国际个人护理品生产商情》杂志,美国《happi》与《Beauty Packaging》杂志在 中国唯一合作伙伴。 在竞争激烈的美妆赛道中,美妆品牌如何走向差异化与高端化,这家微藻合成生物公司希望用新一代藻类提取物 (三角褐指藻提取物、紫球藻提取物、小球藻提取物)助力国产品牌走向高端化、国际化。 MicroZenith@小球藻提取物 抗皱,紧致,祛痘、舒缓、保 湿、抗氧化 1) 微藻活性物密度高5-10倍。海洋微藻一般难以采 用异养等高密度培养方法,但通过合成生物+光控培养 技术可以将微藻细胞密度和生物活性成分提高5-10倍。 2)微藻活性物高品质。传统的跑道池、管式反应器中 重金属或塑化剂的污染难以有效避免和控制,我司开 发了独家专利的新型生物反应器,有效解决污染问题。 3)无菌、无重金属、无农残,无核污染。 ...
值得关注!肆芃科技千吨级生物基PDO、乳酸钙、香兰素等项目进展
合成生物学与绿色生物制造· 2025-06-29 11:18
Core Viewpoint - The article discusses the establishment of a new production line by SiPeng Bio-Materials (Nantong) Co., Ltd., focusing on the production of bio-based products such as 1,3-PDO, calcium lactate, vanillin, and sialic acid, highlighting the company's commitment to sustainable and innovative biomanufacturing practices [1][2]. Group 1: Company Overview - SiPeng Bio-Materials (Nantong) Co., Ltd. was established in July 2024 as a wholly-owned subsidiary of Shanghai SiPeng Technology Co., Ltd., which was founded in May 2022 [1]. - The company focuses on negative carbon synthetic biology and has completed significant funding rounds, including nearly 100 million yuan in a Pre-A round in October 2024 and several million yuan in a Pre-A+ round in May 2025 [1]. Group 2: Production Line Details - The new production line has a total investment of 50 million yuan and is located in the Rugao High-tech Industrial Development Zone [1]. - Upon completion, the production capacity will be 720 tons of 1,3-PDO, 940 tons of calcium lactate, 30 tons of vanillin, and 10 tons of sialic acid annually [1][2]. Group 3: Product Specifications - 1,3-PDO will have a purity of over 99.9% and is intended for use in new textile materials and biodegradable materials, outperforming industry standards [3][4]. - Calcium lactate, a common food additive, is noted for its high bioavailability and mild taste, making it suitable for sensitive populations [6]. - Vanillin produced from biological sources is highlighted for its environmental sustainability and wide applications in food, cosmetics, and pharmaceuticals [8]. - Sialic acid, a natural nine-carbon sugar derivative, is used in various food products, particularly for infants and health supplements [11][12].
容锐科技完成近亿元Pre-A轮融资,加速合成生物学产品商业化
合成生物学与绿色生物制造· 2025-06-29 11:18
Core Viewpoint - Zhejiang Rongrui Technology Co., Ltd. has completed nearly 100 million yuan in Pre-A round financing, which will primarily be used to accelerate product pipeline development and continue the industrialization and commercialization process [1] Company Overview - Founded in 2022, Rongrui Technology focuses on synthetic biology as its core technology, integrating the latest advancements in artificial intelligence to develop disruptive technologies for artificial life and functional molecules [2] - The company aims to achieve green biological manufacturing in areas such as health food ingredients and high-value chemicals, while also reducing product costs and improving quality [2] - The product pipeline includes dozens of successfully developed products, such as important industrial enzyme varieties (lipase, nitrile hydratase, nitrile hydrolase, amide enzyme), pharmaceuticals, pesticides, high-value fine chemicals (chiral alcohols, chiral amines, chiral non-natural amino acids, amide compounds), as well as health oils, new structural esters, vitamins, and sugar substitutes [2] - The company has established multiple collaborations with leading enterprises in its niche [2] Industry Event - The 4th Synthetic Biology and Green Biological Manufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the "1+4" theme: AI + Biological Manufacturing [3] - The conference will cover four major application areas: green chemicals and new materials, future food, future agriculture, and beauty raw materials, inviting international leading companies, representative industrial experts, government, parks, capital, associations, and alliances to explore the development trends of the biological manufacturing industry during the 14th Five-Year Plan [3] - The event aims to promote the transfer and transformation of scientific and technological achievements, product scaling, and talent acquisition [3]
生物制造青年论坛,报告征集中!聚焦科技成果对接,8月20-22日宁波
合成生物学与绿色生物制造· 2025-06-29 11:18
SynBioCon 大会 | 生物制造青年论坛 特色专场 生物制造青年论坛 8月20日,浙江·宁波 生物制造领域有哪些 "潜力股" 团队、技术和产品值 得关注? 为发掘合成生物学和生物制造科研团队创新成果、 促进生物制造领域优秀科研工作者成果交流和产业方对接, 第四届合成生物与绿色生物制造大会 (简称: SynBioCon 2025 ) 同期将举办特色专场——" 生物制造青年论坛 ",于8月20日在浙江宁波举办。 助力行业 15分钟了解一个方向 ,重点阐述研究领域存在的科学问题、解决思路、成果、放大可行性以及未来发展方向。 欢迎高校、科研院所申报分享! 扫码报名,请选择参会形式 报名请选择:青年论坛、科技成果展示 欢迎科研院所、企业报名! 往期现场: 03 大会日程 SynBioCon 2 025 8月20-22日,浙江·宁波 01 论坛信息 时 间: 8月20日(周三) 席 位 : 仅 30 席! 报告时间: 第一场:13:30-17:30; 第二场:19:00-20:30 报名须知 :扫描以上二维码,会务组将第一时间与您确认,并对接报告信息表等; 02 科技成果展示与对接专场 (同期活动) SynBioC ...
人工合成酶效率飙升100倍!生物制造或迎技术革命
合成生物学与绿色生物制造· 2025-06-27 10:42
#SynBio团队 | 以色列魏茨曼科学研究院 【SynBioCon】 获 悉 , 以色列魏茨曼科学研究院科学家在新一期《自然》杂志发表文章称:他们利用基于酶工 作原理的计算机新算法设计出高效人工合成酶。这种新型酶不仅能催化天然蛋白质无法完成的化学反应, 其效率 更达到人工智能(AI)设计酶的100倍 ,标志着"按需定制"高效酶的新阶段即将来临。 传统计算机算法辅助设计的酶往往效率低下,需要耗费大量时间进行实验室优化。为突破这一瓶颈,研究团队独 辟蹊径,选择"肯普消除"(一种涉及从特定底物碳原子上移除质子的非天然化学反应)作为验证案例。 过去十年,AI蛋白质设计大行其道,但其工作机制主要模仿现有酶。相比之下,新算法的工作机制是基于物理原 理来构建酶。研究团队表示,AI在处理某些蛋白质设计时确实无可替代,但对于复杂催化反应仍力不从心。未来 需要将两种方法优势互补,才能设计出更完美的酶。 通过算法设计的一种酶(白色)将底物(红色、黄色和蓝色)包裹于其活性位点内。图片来源:《自然》网站 ▌ 参考信息: 本文部分 素 材 来 自全网 。由 作 者重新 编写,系作者个人观点,本平台发布仅为了传达一种不同观点,不代表对该 ...
SynBioCon 2025第四届合成生物与绿色生物制造大会,8月宁波见!
合成生物学与绿色生物制造· 2025-06-27 10:42
Core Viewpoint - The article emphasizes the importance of biomanufacturing as a key focus for enhancing economic competitiveness in various countries, including China, which is advancing its manufacturing capabilities through initiatives like green manufacturing and intelligent manufacturing [1]. Group 1: Event Overview - The Fourth Synthetic Biology and Green Biomanufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI and biomanufacturing [1]. - The conference aims to explore the development trends of the biomanufacturing industry during the 14th Five-Year Plan period, highlighting innovative technologies and products that will sustain the industry's vitality [1]. Group 2: Organizers and Highlights - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and co-organized by Ningbo Meisai Biological Engineering Co., Ltd. [2]. - Key highlights include forums on biomanufacturing trends, youth innovation sharing, project roadshows, and participation from leading enterprises, top universities, and investment institutions [4]. Group 3: Agenda and Special Activities - The first day features a closed-door high-level seminar focusing on the development trends and growth points of biomanufacturing, with 30 industry leaders and experts invited [7]. - The second and third days will include a macro forum on biomanufacturing, covering the overall trends and progress in the industry [10]. Group 4: Specialized Forums - Specialized forums will cover topics such as green chemicals and new materials, AI in biomanufacturing, future food and agriculture, and beauty raw materials [11]. - The forums will discuss various aspects of biomanufacturing, including the development of bio-based chemicals, green manufacturing technologies, and the application of AI in industrial processes [11]. Group 5: Project Roadshows and Talent Engagement - The conference will feature project roadshows aimed at connecting head parks and investment institutions with innovative biomanufacturing projects [10]. - A youth forum will be held to discover potential teams and technologies in biomanufacturing, providing a platform for efficient talent and collaboration exchanges [10].