Sinobioway Medicine(002581)

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六成营收产品被叫停,未名医药触发ST警报,股价火速跌停
Ge Long Hui· 2025-04-25 09:28
Core Viewpoint - Unimed Pharmaceutical is facing its most severe survival test since its establishment due to significant production management deficiencies identified by the Tianjin Drug Administration, leading to a suspension of production and sales [1][3][5]. Financial Performance - Unimed's subsidiary, Tianjin Unimed, generated revenue of 217 million yuan in 2024, accounting for 60.09% of the company's total revenue, with interferon products contributing over 70% to this figure in the past three years [7][8]. - The company's total revenue for 2024 was approximately 360 million yuan, a decrease of 16.14% compared to 2023, with the interferon segment experiencing a 28.59% decline in revenue [8][10]. - The net loss for the company has been increasing, reaching 137 million yuan in 2024, with a significant quarterly loss of 167 million yuan in Q4 due to the suspension of core products [10][12]. Regulatory and Compliance Issues - This incident marks the second major quality issue for Tianjin Unimed in 2024, following a previous failure of the "human interferon α2b spray" to meet biological activity standards, resulting in procurement suspensions from several provinces [9][12]. - The company has faced continuous non-standard audit opinions for eight consecutive years, raising concerns about the fairness of drug pricing and ownership disputes of subsidiaries [9][12]. Market Reaction - Following the news of the production suspension, Unimed's stock price plummeted to 7.42 yuan per share, hitting the daily limit down, with a total market capitalization of approximately 4.895 billion yuan [3][10]. - The stock has been trading below 10 yuan since the second half of 2024, reflecting a nearly 90% decline from its peak in 2015 [10][12]. Future Outlook - The suspension of production has cut off the company's main cash flow and led to the urgent recall of inventory valued at 23.16 million yuan. If production does not resume within three months, the company may face ST (special treatment) status and potential delisting risks [12]. - The company is attempting to establish a special rectification team, but historical issues and a lack of market confidence complicate recovery efforts [12].
未名医药核心子公司被停产,所产干扰素已遭多地停购
Xin Lang Cai Jing· 2025-04-25 09:04
Core Viewpoint - Unimed Pharmaceutical faces significant operational challenges due to regulatory issues with its subsidiary Tianjin Weiming Biopharmaceutical Co., which has been ordered to suspend production and sales due to non-compliance with drug production quality management standards [1][2]. Group 1: Regulatory Issues - Tianjin Weiming was found to have production practices that do not meet the 2010 revised Drug Production Quality Management Standards, leading to a suspension of production and sales [1]. - The company must complete rectification and inspection before resuming production, which could take up to three months [1]. - If production is not restored within three months, Unimed may face additional risk warnings and could be subject to special treatment (ST) [1]. Group 2: Financial Impact - Following the announcement, Unimed's stock price dropped by 9.95%, closing at 7.42 yuan per share, with a market capitalization of 4.895 billion yuan [1]. - In 2024, Tianjin Weiming generated revenue of 217 million yuan, accounting for 60.09% of Unimed's total revenue, but reported a net loss of 14.0037 million yuan [1][2]. - The recall of a specific batch of interferon α2b spray due to non-compliance resulted in a revenue reduction of 23.1672 million yuan for Unimed [2]. Group 3: Historical Performance - Unimed has experienced fluctuating performance, with five out of the last seven years resulting in losses, particularly since 2018 [3]. - The company has faced multiple operational setbacks, including the suspension of its subsidiary Weiming Tianyuan due to environmental regulations and significant revenue declines in its core products [3][4]. - The ongoing control disputes over Beijing Kexing have further complicated Unimed's operational stability and financial performance [4]. Group 4: Current Business Structure - Unimed's operations are heavily reliant on three key subsidiaries: Tianjin Weiming, Xiamen Weiming, and Beijing Kexing [5]. - The revenue from the previously significant product, nerve growth factor, has decreased to 139 million yuan, representing only 38.59% of total revenue in 2024 [5]. - With Tianjin Weiming's current regulatory issues, Unimed faces potential operational crises as it relies on this subsidiary for a substantial portion of its income [5].
未名医药跌停!子公司停产暴露生产乱象,药品安全岂能儿戏
Mei Ri Jing Ji Xin Wen· 2025-04-25 05:15
Core Viewpoint - Unimed Pharmaceutical's subsidiary Tianjin Unimed has been suspended from production and sales due to non-compliance with drug production quality management standards, significantly impacting the company's operations and raising concerns about its internal controls and compliance management [1][2]. Group 1: Company Impact - Tianjin Unimed, a key subsidiary, accounted for 60.09% of Unimed Pharmaceutical's revenue in 2024, generating 217 million yuan [1]. - The suspension of production is expected to exacerbate Unimed Pharmaceutical's operational difficulties, with a projected revenue decline of 16.14% to 360 million yuan and a net loss of 137 million yuan in 2024, representing a 58.70% increase in losses [2]. - The company's stock price fell to the daily limit on April 25, reflecting investor concerns about the ongoing situation [2]. Group 2: Regulatory and Compliance Issues - The suspension was triggered by violations of the 2010 revised Drug Production Quality Management Standards, indicating serious quality management issues within the company [1]. - The company has established a special rectification team to address the root causes and develop a corrective action plan, although the timeline for resuming production remains uncertain [2]. - The incident serves as a warning for the entire industry regarding the importance of adhering to drug production quality standards to ensure patient safety [1].
21健讯Daily | 七部门:开展“人工智能赋能医药全产业链”应用试点;万泰生物第一季度净亏损5277.69万元
2 1 Shi Ji Jing Ji Bao Dao· 2025-04-25 01:10
Policy Developments - Seven departments, including the Ministry of Industry and Information Technology, issued the "Implementation Plan for the Digital Transformation of the Pharmaceutical Industry (2025-2030)", emphasizing the integration of artificial intelligence across the pharmaceutical supply chain [1] Drug and Device Approvals - Kangtai Biological announced that its subsidiary Minhai Biological's application for the marketing authorization of an adsorbed tetanus vaccine has been accepted by the National Medical Products Administration [2] - Hendi Pharmaceutical received approval for the marketing application of arginine ibuprofen, a non-steroidal anti-inflammatory drug with superior solubility and faster absorption compared to regular ibuprofen [3] - Tianyao Pharmaceutical's subsidiary obtained a drug registration certificate for injectable hydrocortisone sodium succinate, used for critical conditions such as allergic shock and severe adrenal insufficiency [4] Financial Reports - Wantai Biological reported a net loss of 52.78 million yuan in Q1 2025, with revenue of 401 million yuan, a year-on-year decline of 46.76%, primarily due to market adjustments and government procurement impacts [5] - Heng Rui Pharmaceutical's Q1 2025 report showed a revenue of 7.206 billion yuan, a year-on-year increase of 20.14%, and a net profit of 1.874 billion yuan, up 36.9%, largely due to a licensing payment from IDEAYA [6] - Kingstone Pharma reported a revenue of 291 million yuan in Q1 2025, down 19.65%, with a net profit of 62.85 million yuan, a decrease of 30.02% [8] - Baijun Medical achieved a revenue of 100 million yuan in Q1 2025, a 31.3% increase, with a net profit of 32.50 million yuan, up 290.69%, driven by stable sales of existing products and successful new product launches [9] Capital Market Activities - Tonghe Pharmaceutical plans to invest 11 million yuan to increase its stake in Hangzhou Boya Biomedical Co., Ltd., raising its ownership from 16.34% to 24.93% [10] - Chengyuan Biotechnology announced the completion of several million yuan in equity financing, aimed at upgrading its gene synthesis technology platform [11] Industry Developments - Zhang Wenhong's team announced significant progress in developing a broad-spectrum antiviral drug for monkeypox, which is set to enter clinical approval stages [12] - Qianxin Biotechnology signed a licensing agreement with Caldera Therapeutics for its long-acting dual antibody QX030N, granting global exclusive rights for development and commercialization [13] Public Sentiment Alerts - Weiming Pharmaceutical announced that its important subsidiary, Tianjin Weiming, was suspended from production and sales, which could trigger further risk warnings if production does not resume within three months [14]
上市公司动态 | 爱尔眼科一季度净利润降11.82%,同花顺2024年净利润增30%,亿纬锂能一季度营收扣非净利双增
Sou Hu Cai Jing· 2025-04-24 15:49
Group 1: Aier Eye Hospital - In 2024, Aier Eye Hospital achieved an outpatient volume of 16.94 million, a year-on-year increase of 12.14% [1] - The company reported a total revenue of 20.98 billion yuan, reflecting a growth of 3.02% compared to the previous year [2] - The net profit attributable to shareholders was 3.56 billion yuan, up by 5.87% year-on-year [2] - The company introduced several advanced medical technologies and products, including the INTENSITY™ intraocular lens and new dry eye treatment technology [1][3] Group 2: Tonghuashun - Tonghuashun reported a revenue of 4.19 billion yuan in 2024, marking a 17.47% increase from the previous year [5] - The net profit attributable to shareholders reached 1.82 billion yuan, a significant growth of 30% year-on-year [4][5] - The increase in revenue and profit was primarily driven by a recovery in the securities market and rising demand for financial information services [4] Group 3: Yiwei Lithium Energy - Yiwei Lithium Energy achieved a revenue of 1.28 billion yuan in Q1 2025, with a net profit of 110.11 million yuan, reflecting a 16.60% increase in net profit [7] - The company reported a significant increase in the shipment of energy storage batteries, with a year-on-year growth of 80.54% [8] - The company is expanding into emerging markets such as eVTOL and drones, with ongoing projects and production facilities being established [9] Group 4: Huadong Medicine - Huadong Medicine reported a revenue of 10.74 billion yuan in Q1 2025, a 3.12% increase year-on-year [10] - The net profit attributable to shareholders was 914.71 million yuan, up by 6.06% compared to the same period last year [11] - The company achieved its highest historical level of net profit excluding non-recurring gains and losses, reaching 897.34 million yuan [10] Group 5: Muyuan Foods - Muyuan Foods reported a revenue of 36.06 billion yuan in Q1 2025, a year-on-year increase of 37.26% [17] - The company turned a profit with a net profit of 44.91 billion yuan, compared to a loss of 23.79 billion yuan in the same period last year [18] - The significant growth was attributed to increased pig prices and sales [17] Group 6: China Aluminum - China Aluminum reported a revenue of 55.78 billion yuan in Q1 2025, with a net profit of 3.54 billion yuan, reflecting a year-on-year increase of 58.78% [21] - The company successfully managed market price fluctuations, resulting in increased product sales and profits [21] Group 7: Hengrui Medicine - Hengrui Medicine achieved a revenue of 72.06 billion yuan in Q1 2025, a 20.14% increase year-on-year [22] - The net profit attributable to shareholders was 18.74 billion yuan, up by 36.9% compared to the previous year [22] - The increase in profit was significantly influenced by a licensing payment received during the reporting period [22] Group 8: Bull Group - Bull Group reported a revenue of 16.83 billion yuan in 2024, reflecting a 7.24% increase year-on-year [13] - The net profit attributable to shareholders was 4.27 billion yuan, a growth of 10.39% compared to the previous year [13] - The company experienced growth in its electrical connection and smart lighting businesses, as well as rapid development in its new energy sector [14]
突发公告!重要子公司被罚停产,这家A股公司触发ST情形
21世纪经济报道· 2025-04-24 14:56
Core Viewpoint - Unimed Pharmaceutical's subsidiary, Tianjin Unimed Biopharmaceutical Co., has been suspended from production and sales due to non-compliance with GMP standards, which may significantly impact the company's operations and could lead to further risk warnings if production does not resume within three months [1][6]. Financial Performance - In 2024, Tianjin Unimed generated revenue of 217 million yuan and a net profit of -14.0037 million yuan, accounting for 60.09% of Unimed's total revenue and 9.8% of its consolidated net profit [4]. - Unimed's 2024 annual report indicated a total revenue of 360 million yuan, a year-on-year decrease of 16.14%, and a net loss of 137 million yuan, with losses widening by 58.70% compared to the previous year [8]. Regulatory Actions - The suspension was initiated following a GMP compliance inspection by the Tianjin Municipal Drug Administration, which found that Tianjin Unimed's production practices did not meet the required standards [5][6]. - In response, Unimed has established a special rectification team to identify issues and develop a corrective action plan while cooperating with regulatory authorities to address deficiencies [7]. Market Reaction - Following the announcement, Unimed's stock price fell by 2.49%, closing at 8.24 yuan per share, with a total market capitalization of 5.436 billion yuan [9].
突发公告!重要子公司被罚停产,这家上市药企或触发ST情形
2 1 Shi Ji Jing Ji Bao Dao· 2025-04-24 14:11
关于应对措施,未名医药公告表示,公司已成立专项整改小组,全面排查问题根源,制定整改方案,并 积极配合监管部门完成缺陷整改工作,争取尽快恢复生产。 公开资料显示,未名医药主营业务为为干扰素、神经生长因子、生物医药CRO/CDMO、疫苗和医药中 间体等五大生物医药板块,公司重点发展人干扰素α2b系列产品,主要产品捷抚-重组人干扰素α2b喷雾 剂(假单胞菌),是全球第一支干扰素喷雾剂。其子公司天津未名是我国率先进入基因工程制药产业化 领域的企业之一。 4月23日晚,未名医药披露了2024年年报。财报显示,公司去年实现营业收入3.60亿元,同比减少 16.14%;归母净利润-1.37亿元,亏损同比扩大58.70%。 截至今日收盘,未名医药下跌2.49%,最新价报8.24元/股,总市值达54.36亿元。 (声明:文章内容仅供参考,不构成投资建议。投资者据此操作,风险自担。) 4月24日晚间,未名医药(002581.SZ)突发公告称,公司控股子公司天津未名生物医药有限公司(简 称"天津未名")于4月22日被天津市药品监督管理局采取暂停生产、销售风险控制措施。 未名医药表示,天津未名为公司重要子公司,本次暂停生产、销售事项 ...
未名医药:重要子公司被暂停生产 若三个月内无法恢复生产公司可能触发其他风险警示
news flash· 2025-04-24 11:58
Core Viewpoint - The company, Weiming Pharmaceutical, faces significant operational challenges due to the suspension of production and sales at its key subsidiary, Tianjin Weiming, which may lead to further risk warnings if production is not resumed within three months [1] Group 1: Company Impact - Tianjin Weiming, a major subsidiary, was ordered to suspend production and sales by the Tianjin Municipal Drug Administration on April 22, 2025 [1] - In 2024, Tianjin Weiming generated revenue of 217 million yuan and reported a net loss of 14.0037 million yuan, accounting for 60.09% of the company's total revenue and 9.8% of the consolidated net profit [1] - The suspension of operations is expected to have a significant impact on the company's overall business performance [1] Group 2: Risk Factors - If Tianjin Weiming is unable to resume production within three months, the company may trigger additional risk warnings [1]
未名医药(002581) - 关于控股子公司暂停生产、销售及风险提示的公告
2025-04-24 11:55
2、根据《深圳证券交易所股票上市规则》(2024 年修订)9.8.1 条第(五) 项规定:公司生产经营活动受到严重影响且预计在三个月内不能恢复正常,公司 股票将被实施其他风险警示。公司因天津未名停产导致主营业务受到严重影响。 截止本公告披露之日,公司仍具有生产经营的能力,且天津未名预计停产时间不 超过三个月。如天津未名三个月内无法恢复生产,则公司可能触发其他风险警示 的情形。 一、暂停生产、销售概况 2025 年 4 月 22 日,天津市药品监督管理局发布《关于暂停天津未名生物医 药有限公司生产销售的公告》,天津市药品监督管理局对天津未名生物医药有限 公司进行了药品 GMP 符合性检查。经综合评定、研判,天津未名生物医药有限公 司相关药品生产行为不符合《药品生产质量管理规范》(2010 年修订)要求。为 控制药品质量安全风险和隐患,依据《中华人民共和国药品管理法》第九十九条 证券代码:002581 证券简称:未名医药 公告编号:2025-020 山东未名生物医药股份有限公司 关于控股子公司暂停生产、销售及风险提示的公告 本公司及董事会全体成员保证信息披露内容的真实、准确和完整,不存在虚假 记载、误导性陈述或重 ...
4月24日早间重要公告一览
Xi Niu Cai Jing· 2025-04-24 05:05
Group 1 - Yilida plans to repurchase shares worth 30 to 50 million yuan for employee stock ownership plans, with a maximum price of 6.5 yuan per share [1] - Yinglian shares two major shareholders plan to reduce their holdings by up to 5% [1][2] - Zhongbing Hongjian reports a net loss of 327 million yuan for 2024, with a revenue decline of 25.29% [2][3] Group 2 - Zhongke Electric reports a net profit increase of 626.56% for 2024, with a revenue growth of 13.72% [3][4] - Yong'an Futures reports a net profit decline of 21.07% for 2024, with a revenue decrease of 8.76% [5][6] - Yongjie New Materials reports a net profit increase of 34.28% for 2024, with a revenue growth of 24.71% [7][8] Group 3 - Xibu Securities reports a net profit increase of 20.38% for 2024, despite a revenue decline of 2.64% [9][10] - Jinying Heavy Industry reports a net profit decline of 35.54% for 2024, with a slight revenue increase of 1.13% [10][11] - Haineng Industry reports a net profit decline of 40.45% for 2024, despite a revenue growth of 16.26% [12][13] Group 4 - Penghui Energy reports a net loss of 252 million yuan for 2024, with a revenue increase of 14.83% [14][15] - Weiming Pharmaceutical reports a net loss of 137 million yuan for 2024, with a revenue decline of 16.14% [16][17] - Huachang Technology reports a net profit increase of 184.26% for 2024, with a revenue growth of 6.74% [18][19] Group 5 - Ancar Detection reports a net loss of 213 million yuan for 2024, with a revenue decline of 3.05% [20][21] - Saiwei Intelligent reports a net loss of 507 million yuan for 2024, with a significant revenue decline of 68.03% [22][23] - Qinglong Pipe Industry reports a net profit increase of 976.43% for 2024, with a revenue growth of 36.71% [24][25] Group 6 - Huayin Electric reports a net loss of 113 million yuan for 2024, with a revenue decline of 16.00% [26][27] - Zhongqi New Materials reports a net profit decline of 61.59% for 2024, with a revenue decrease of 22.88% [28][29] - Guangzheng Eye Hospital reports a net loss of 175 million yuan for 2024, with a revenue decline of 16.94% [30][31] Group 7 - Zhenlan Instrument reports a net profit increase of 2.16% for 2024, with a revenue growth of 11.63% [32][33] - Zaiseng Technology reports a net profit increase of 137.99% for 2024, despite a revenue decline of 10.87% [34][35] - Haitai High-tech reports a net profit increase of 51.34% for 2024, with a revenue growth of 25.26% [36][37] Group 8 - Runze Technology reports a net profit increase of 1.62% for 2024, with a revenue growth of 0.32% [38][39]