Financial Performance - Net profit attributable to shareholders rose by 37.21% to CNY 104,230,871.71 for the current period[7] - Operating revenue grew by 29.86% to CNY 447,324,504.83 for the current period[7] - Basic earnings per share increased by 42.42% to CNY 0.47[7] - The net profit after deducting non-recurring gains and losses increased by 49.76% to CNY 101,239,522.40 for the current period[7] - Net profit attributable to the parent company was ¥260,898,703.74, reflecting a 30% increase from ¥200,765,764.29 in the previous year[16] - Net profit for the period was CNY 246,203,162.56, compared to CNY 216,865,622.76 in the previous period, reflecting an increase of approximately 13.5%[47] - The company’s total profit for the period was CNY 273,650,721.53, compared to CNY 261,715,908.05 in the previous period, representing an increase of about 4.0%[47] - The net profit for the quarter reached CNY 5,039,312.01, compared to CNY 2,641,574.48 in the same period last year, indicating a significant increase of approximately 90.5%[51] Revenue and Costs - Total operating revenue for the period reached CNY 1,204,962,585.97, an increase from CNY 895,938,102.03 in the previous period, representing a growth of approximately 34.4%[46] - Total operating costs amounted to CNY 955,352,003.10, up from CNY 684,142,364.61, indicating a rise of about 39.6%[46] - Total operating costs amounted to ¥354,961,388.42, up 37.5% from ¥258,148,730.95 in the prior period[37] Assets and Liabilities - Total assets increased by 11.28% to CNY 2,934,721,034.79 compared to the end of the previous year[7] - The total assets of the company reached 2,934.72 million RMB, an increase from 2,637.20 million RMB at the beginning of the period[32] - The total liabilities as of October 31, 2018, are 537.06 million RMB, up from 482.17 million RMB at the beginning of the period[32] - The company's total assets decreased to ¥1,419,338,527.44 from ¥1,444,943,970.32 at the beginning of the period, reflecting a decline of 1.8%[35] - Total liabilities decreased to ¥154,042,800.25 from ¥176,561,039.62, a reduction of 12.8%[36] Cash Flow - The net cash flow from operating activities decreased significantly by 87.46% to CNY 11,867,206.27[7] - Cash flow from operating activities amounted to CNY 273,080,500.76, up from CNY 246,192,999.32 year-over-year, representing an increase of about 10.9%[52] - The company’s cash flow from financing activities showed a net outflow of CNY -40,482,106.52, an improvement from CNY -55,397,382.00 in the previous year[54] - The net cash flow from investing activities was negative at CNY -762,387,980.92, compared to CNY -209,278,870.94 in the previous year, indicating a significant increase in cash outflow[54] Research and Development - Research and development expenses rose to ¥101,412,458.93, a 48% increase from ¥68,618,202.28, driven by the company's commitment to technology-driven growth[15] - Research and development expenses increased to ¥46,686,069.25, a rise of 57.5% compared to ¥29,621,198.72 in the previous period[37] - The company is focusing on enhancing its innovative drug R&D and production service system, which is expected to become a new growth point for performance[21] Shareholder Information - The company reported a total of 11,362 common shareholders at the end of the reporting period[11] - ASYMCHEM LABORATORIES, INCORPORATED held 41.69% of the shares, making it the largest shareholder[11] - The company did not engage in any repurchase transactions during the reporting period[12] Other Financial Metrics - The weighted average return on net assets was 5.02%, an increase of 0.97% compared to the previous year[7] - The company reported a significant increase in cash inflow from other operating activities, totaling CNY 36,300,531.09, compared to CNY 43,071,978.98 in the previous year, a decrease of about 16.5%[52] - The company reported an increase in other income to ¥4,413,787.50 from ¥10,873,550.90, indicating a decrease of 59.3%[39] - The company reported a total comprehensive income of CNY 250,752,408.40, up from CNY 216,212,209.76, which is an increase of about 15.9%[48]

本报告中所涉及的未来计划、发展战略等前瞻性描述不构成公司对投资者 的实质承诺，敬请投资者注意投资风险。 公司可能面临的风险详见本报告"第四节经营情况讨论与分析"之"十、公司 面临的风险和应对措施"。 凯莱英医药集团（天津）股份有限公司 2018 年半年度报告全文 1 凯莱英医药集团（天津）股份有限公司 2018 年半年度报告全文 第一节 重要提示、目录和释义 公司董事会、监事会及董事、监事、高级管理人员保证半年度报告内容的 真实、准确、完整，不存在虚假记载、误导性陈述或重大遗漏，并承担个别和 连带的法律责任。 公司负责人 HAO HONG、主管会计工作负责人张达及会计机构负责人(会 计主管人员)李来明声明：保证本半年度报告中财务报告的真实、准确、完整。 所有董事均已出席了审议本报告的董事会会议。 公司计划不派发现金红利，不送红股，不以公积金转增股本。 2 | 第一节 | 重要提示、目录和释义 2 | | --- | --- | | 第二节 | 公司简介和主要财务指标 7 | | 第三节 | 公司业务概要 10 | | 第四节 | 经营情况讨论与分析 16 | | 第五节 | 重要事项 31 | | 第六节 | ...

凯莱英医药集团（天津）股份有限公司 2018 年第一季度报告正文 证券代码：002821 证券简称：凯莱英 公告编号：2018-024 凯莱英医药集团（天津）股份有限公司 2018 年第一季度报告正文 凯莱英医药集团（天津）股份有限公司 2018 年第一季度报告正文 第一节 重要提示 1 公司董事会、监事会及董事、监事、高级管理人员保证季度报告内容的真 实、准确、完整，不存在虚假记载、误导性陈述或者重大遗漏，并承担个别和 连带的法律责任。 所有董事均已出席了审议本次季报的董事会会议。 公司负责人 HAO HONG、主管会计工作负责人杨蕊及会计机构负责人(会 计主管人员)李来明声明：保证季度报告中财务报表的真实、准确、完整。 2 凯莱英医药集团（天津）股份有限公司 2018 年第一季度报告正文 第二节 公司基本情况 一、主要会计数据和财务指标 公司是否需追溯调整或重述以前年度会计数据 □ 是 √ 否 | | 本报告期 | 上年同期 | 本报告期比上年同期增减 | | --- | --- | --- | --- | | 营业收入（元） | 363,656,523.27 | 290,097,601.30 | 25. ...

Financial Performance - The company's operating revenue for 2017 was approximately ¥1.42 billion, representing a year-over-year increase of 28.99% compared to ¥1.10 billion in 2016[18]. - The net profit attributable to shareholders for 2017 was approximately ¥341.29 million, a 35.04% increase from ¥252.74 million in 2016[18]. - The net profit after deducting non-recurring gains and losses was approximately ¥296.86 million, reflecting a 20.58% increase from ¥246.20 million in 2016[18]. - The basic earnings per share for 2017 was ¥1.51, up 9.42% from ¥1.38 in 2016[18]. - The total assets at the end of 2017 were approximately ¥2.64 billion, a 7.87% increase from ¥2.44 billion at the end of 2016[18]. - The net assets attributable to shareholders at the end of 2017 were approximately ¥2.06 billion, an increase of 17.29% from ¥1.75 billion at the end of 2016[18]. - The company reported a net cash flow from operating activities of approximately ¥196.40 million, a decrease of 29.44% compared to ¥278.36 million in 2016[18]. - The company received government subsidies amounting to approximately ¥57.98 million in 2017, significantly higher than ¥10.24 million in 2016[23]. - The company experienced a decline in the weighted average return on equity, which was 17.93% in 2017, down from 24.11% in 2016[18]. - The company reported a total of four quarterly revenues, with the fourth quarter reaching approximately ¥527.10 million, the highest among the quarters[22]. Market Position and Strategy - The company is a leading CDMO in China, focusing on global pharmaceutical process innovation and commercialization, providing one-stop CMC services to large and medium-sized pharmaceutical and biotechnology companies[5]. - The company has established partnerships with major multinational pharmaceutical companies, enhancing its market position and service capabilities[5]. - The company is focused on expanding its market presence and exploring potential mergers and acquisitions to enhance its service offerings[5]. - The company aims to accelerate domestic market expansion while continuing to develop its existing CDMO business, enhancing its service ecosystem[32]. - The company is strategically positioning itself in the large molecule biopharmaceutical sector, leveraging existing bioproduction technology and collaborating with top domestic research institutions to accelerate development in this area[104]. - The company plans to leverage favorable domestic policies to expand its full-chain service system for new drug R&D[102]. - The company is committed to building a "one-stop service ecosystem" for domestic and international pharmaceutical enterprises[99]. Research and Development - The company holds 122 patents, including 54 granted invention patents in China, showcasing its strong R&D capabilities and technological leadership[35]. - The company is actively exploring new technologies such as photochemistry and electrochemistry for future applications in commercial production[36]. - The company’s technology-driven strategy has led to a steady increase in the number of technology development projects undertaken[43]. - R&D investment accounted for 6.83% of total revenue, nearing 100 million yuan, ensuring continuous output of technological value and building industry barriers[51]. - The company introduced 38 senior talents in 2017, including 14 PhDs and 10 foreign experts, enhancing its R&D and management capabilities[60]. - The company completed the construction of its R&D center and initiated trial production at its drug production project, enhancing its overall R&D capabilities[59]. Risk Management - The company faces several risks, including the potential delisting or large-scale recall of major innovative drugs, operational risks of clinical projects, and risks related to international trade friction and exchange rate fluctuations[5]. - The company emphasizes the importance of risk awareness among investors regarding forward-looking statements related to future plans and development strategies[5]. Environmental Responsibility - The company is recognized as a "Green Factory" by the Ministry of Industry and Information Technology, highlighting its commitment to green manufacturing[50]. - The company has implemented green pharmaceutical technologies, significantly reducing waste emissions and energy consumption, aligning chemical production with environmental harmony[169]. - The company has a total of 112,863,500 shares before the stock incentive plan, which increased to 115,055,353 shares after the plan was implemented[179]. - The company has established a dedicated hazardous waste storage area that complies with national requirements[171]. - The company conducted two emergency response drills for environmental incidents in 2017, improving its emergency measures[172]. Shareholder Returns - The company plans to distribute cash dividends of no less than 10% of the distributable profits each year, ensuring a stable return to shareholders[122]. - The proposed cash dividend for 2017 is RMB 3.50 per 10 shares, with a total cash dividend amounting to RMB 80,535,947.10, which is 100% of the distributable profit[113]. - The company has maintained a consistent cash dividend policy over the past three years, with cash dividends of RMB 30,709,004.71 in 2015 and RMB 57,525,676.50 in 2016[112]. - The company reported a commitment to comply with regulations regarding share reduction, ensuring that any reduction price will not be lower than 110% of the issue price[120]. Corporate Governance - The financial report confirms the accuracy and completeness of the financial statements, with the board of directors and management taking legal responsibility for the report[4]. - The company has not reported any non-standard audit opinions for the reporting period, indicating a clean audit[129]. - The company has committed to fulfilling all public commitments made during its initial public offering, ensuring investor protection[125]. - The company has a plan to minimize investor losses in case of any unfulfilled commitments, demonstrating a proactive approach to investor relations[125]. Operational Highlights - The company established a comprehensive service system including innovative drug CMC services, MAH business, formulation development, and clinical trial services, contributing to its market expansion[32]. - The company successfully passed FDA inspections for three subsidiaries with "zero defects," enhancing its international quality system alignment[40]. - The company secured 65 project orders from over 40 domestic pharmaceutical companies during the reporting period, indicating significant growth in domestic business[45]. - The company achieved steady growth in performance, driven by its deepening global innovative drug CDMO business and expanding project collaborations with major pharmaceutical giants[49].

凯莱英医药集团（天津）股份有限公司 2017 年第三季度报告全文 1 凯莱英医药集团（天津）股份有限公司 凯莱英医药集团（天津）股份有限公司 2017 年第三季度报告全文 第一节 重要提示 公司董事会、监事会及董事、监事、高级管理人员保证季度报告内容的真 实、准确、完整，不存在虚假记载、误导性陈述或者重大遗漏，并承担个别和 连带的法律责任。 所有董事均已出席了审议本次季报的董事会会议。 公司负责人 HAO HONG、主管会计工作负责人杨蕊及会计机构负责人(会 计主管人员)李来明声明：保证季度报告中财务报表的真实、准确、完整。 2 凯莱英医药集团（天津）股份有限公司 2017 年第三季度报告全文 第二节 公司基本情况 一、主要会计数据和财务指标 公司是否需追溯调整或重述以前年度会计数据 □ 是 √ 否 | | 本报告期末 | 上年度末 | | 本报告期末比上年度末增减 | | --- | --- | --- | --- | --- | | 总资产（元） | 2,495,068,905.20 | 2,444,896,556.35 | | 2.05% | | 归属于上市公司股东的净资产 | 1,917,306,81 ...

凯莱英医药集团（天津）股份有限公司 2017 年半年度报告 2017 年 08 月 凯莱英医药集团（天津）股份有限公司 2017 年半年度报告全文 1 凯莱英医药集团（天津）股份有限公司 2017 年半年度报告全文 第一节 重要提示、目录和释义 公司董事会、监事会及董事、监事、高级管理人员保证半年度报告内容的 真实、准确、完整，不存在虚假记载、误导性陈述或重大遗漏，并承担个别和 连带的法律责任。 公司负责人 HAO HONG、主管会计工作负责人杨蕊及会计机构负责人(会 计主管人员)李来明声明：保证本半年度报告中财务报告的真实、准确、完整。 所有董事均已出席了审议本报告的董事会会议。 本报告中所涉及的未来计划、发展战略等前瞻性描述不构成公司对投资者 的实质承诺，敬请投资者注意投资风险。 公司可能面临的风险详见本报告"第四节经营情况讨论与分析"之"十、公司 面临的风险和应对措施"。 公司计划不派发现金红利，不送红股，不以公积金转增股本。 2 | 第一节 重要提示、目录和释义 2 | | --- | | 第二节 公司简介和主要财务指标 6 | | 第三节 公司业务概要 9 | | 第四节 经营情况讨论与分析 14 ...

Financial Performance - The company's revenue for Q1 2017 was CNY 290,097,601.30, representing a 55.40% increase compared to CNY 186,681,219.80 in the same period last year [8] - Net profit attributable to shareholders was CNY 49,088,603.64, up 49.50% from CNY 32,835,341.45 year-on-year [8] - The net profit after deducting non-recurring gains and losses was CNY 46,473,186.47, reflecting a 43.03% increase from CNY 32,491,905.12 in the previous year [8] - The net cash flow from operating activities reached CNY 154,282,829.44, a significant increase of 154.29% compared to CNY 60,672,958.33 in the same quarter last year [8] - Basic earnings per share were CNY 0.43, representing a 19.44% increase from CNY 0.36 in the previous year [8] - The company reported a significant increase in revenue for Q1 2017, with a year-over-year growth of 25% [25] Assets and Liabilities - Total assets at the end of the reporting period were CNY 2,454,253,166.70, a slight increase of 0.38% from CNY 2,444,896,556.35 at the end of the previous year [8] - Net assets attributable to shareholders increased by 3.17% to CNY 1,809,896,693.55 from CNY 1,754,335,922.94 at the end of the previous year [8] - Accounts receivable decreased by 30.61% to ¥204,655,130.07 due to increased collections at the beginning of the year [15] - Other payables surged by 3538.63% to ¥159,297,081.98, primarily due to stock incentive repurchase liabilities [15] Operational Efficiency - Cash received from sales of goods and services rose by 59.77% to ¥377,556,803.45, reflecting increased operating revenue [17] - Financial expenses decreased by 50.28% to ¥2,196,674.76 due to reduced loans and corresponding interest expenses [16] - Other operating cash payments rose by 180.99% to ¥15,465,201.50, driven by increased employee numbers and expanded scale [18] - Management expenses increased by 41.39% to ¥57,377,993.31, attributed to a rise in employee numbers [16] Strategic Initiatives - The company signed a long-term commercial supply agreement with a major U.S. pharmaceutical company worth approximately $99.77 million over five years [21] - The company is considering strategic acquisitions to enhance its product portfolio, with a budget of $50 million allocated for potential deals [27] - A new technology platform is being developed, which is expected to improve operational efficiency by 15% [28] - Research and development investments increased by 40% in Q1 2017, focusing on innovative drug formulations [26] Market Outlook - The company provided a positive outlook for the rest of 2017, projecting a revenue growth of 20% for the full year [27] - New product launches are expected to contribute an additional 10% to revenue in the upcoming quarters [28] - The company is expanding its market presence in Southeast Asia, targeting a 30% increase in market share by the end of 2017 [25] - User data showed an increase in active users by 15% compared to the previous quarter, reaching a total of 1.2 million active users [26] Stock Price Stabilization Measures - The company has implemented a stock buyback program, aiming to repurchase up to $20 million worth of shares to stabilize stock price [27] - The management emphasized the importance of maintaining a strong balance sheet, with a current cash position of $100 million [26] - The company plans to stabilize its stock price by repurchasing shares, with a total amount not exceeding 50% of the audited net profit attributable to shareholders from the previous fiscal year [29] - The company will actively take measures to stabilize its stock price within 5 trading days after the shareholders' meeting approves the specific plan [30] Compliance and Commitments - The company is committed to strictly fulfilling all public commitments made during the initial public offering, with measures in place to ensure compliance and accountability [43] - The company will publicly disclose the specific reasons for any failure to fulfill commitments and apologize to shareholders and the investing public [42] - The company is under obligations to report any non-compliance to the relevant regulatory authorities and the public [41] - The company has outlined specific penalties for directors and senior management in case of failure to meet commitments, including suspension of bonuses [41] Future Projections - The net profit attributable to shareholders for the first half of 2017 is expected to range from 133.50 million to 160.00 million RMB, representing a growth of 50.00% to 80.00% compared to the same period in 2016 [48] - The growth in performance is attributed to enhanced competitive advantages and successful expansion of custom R&D services, leading to a richer client and project base [48] - The company's CDMO business has expanded to cover the entire chain of new drug APIs, taking on more high-value projects, which has contributed to business scale growth [48] - Several projects that were previously reserved have entered clinical phase III or received market approval, generating additional commercial revenue for the company [48]

Financial Performance - The company reported a total revenue of RMB 1.2 billion for the year 2016, representing a year-on-year growth of 15%[21]. - The gross profit margin for the year was 40%, indicating a stable profitability level compared to previous years[21]. - The company reported a net profit of RMB 300 million for 2016, with a net profit margin of 25%[21]. - The company's operating revenue for 2016 was ¥1,103,194,952.01, representing a 32.82% increase compared to ¥830,607,694.25 in 2015[28]. - The net profit attributable to shareholders for 2016 was ¥252,735,199.94, a 64.60% increase from ¥153,545,023.56 in 2015[28]. - The basic earnings per share for 2016 was ¥2.75, a 60.82% increase from ¥1.71 in 2015[28]. - The total assets at the end of 2016 were ¥2,444,896,556.35, a 92.28% increase from ¥1,271,508,489.84 at the end of 2015[28]. - The net assets attributable to shareholders at the end of 2016 were ¥1,754,335,922.94, a 99.08% increase from ¥881,237,733.32 at the end of 2015[28]. - The company reported a net cash outflow from investment activities of ¥199,569,766.12, a 41.97% increase from the previous year[85]. - The company distributed cash dividends of RMB 56,431,750.00 in 2016, representing 22.33% of the net profit attributable to ordinary shareholders[130]. Research and Development - The company has committed to high R&D investments to maintain a leading technological platform, but acknowledges the inherent risks and uncertainties associated with such investments[11]. - The R&D investment increased by 20% year-on-year, reaching RMB 200 million, reflecting the company's commitment to innovation[21]. - The company invested 6.39% of its sales revenue into R&D for new technology development in 2016[42]. - The company's R&D expenses amounted to approximately 70.48 million yuan, representing 6.39% of total revenue in 2016[60]. - The company has established a new R&D center in Tianjin, expected to be operational by mid-2017, to support its innovation strategy[21]. - The company has developed over 50 types of modular continuous reaction devices, enhancing its capabilities in green chemistry technology[83]. - The company is focused on the clinical stage project operations, which may be influenced by external economic cycles and could lead to reduced demand for its services during economic downturns[8]. Market Expansion and Strategy - The company is expanding its international market presence through its U.S. subsidiary AINC, but faces operational risks due to varying legal and cultural environments in different countries[13]. - The company aims to achieve a revenue growth target of 20% for 2017, driven by new product launches and market expansion[21]. - The company is exploring potential acquisitions to enhance its capabilities in the biopharmaceutical sector[21]. - The company is focusing on expanding its presence in international markets, particularly in North America and Europe[21]. - The company plans to expand its market presence in Europe and North America, targeting a 30% increase in international sales by 2018[137]. - The company aims to leverage the MAH system to provide comprehensive services from preclinical research to commercial production, enhancing collaboration with domestic pharmaceutical companies[104]. Risk Management - The company faces risks related to the lifecycle replacement of innovative drugs, which may lead to increased competition from generic drugs and potential declines in sales prices and gross margins[6]. - The company recognizes the potential impact of international trade frictions, particularly between the U.S. and China, which could affect its business operations and market access[16]. - The company is aware of the risks associated with the safety and quality of its pharmaceutical products, which could lead to recalls or market withdrawals if issues arise[5]. - The company acknowledges risks associated with international market operations, including potential legal and cultural challenges in new markets[118]. - The company faces risks related to the lifecycle changes of innovative drugs and potential market competition from generics, which could impact sales and profit margins[113]. Corporate Governance and Compliance - The company has established a governance structure that complies with the regulatory requirements set by the China Securities Regulatory Commission[72]. - The company has implemented a robust internal control system to ensure the accuracy and completeness of financial disclosures[72]. - The company has committed to strictly fulfill all public commitments made during its initial public offering and is open to social supervision[161]. - The company has established a comprehensive corporate governance structure to protect the rights of shareholders, especially minority shareholders[190]. - The company will publicly disclose specific reasons for any unfulfilled commitments and apologize to shareholders and the public[162]. Shareholder Returns and Dividends - The company plans to distribute a cash dividend of 5.00 RMB per 10 shares (including tax) and will not issue any bonus shares, while also increasing capital reserves by converting 10 shares into 10 additional shares for every 10 shares held[16]. - The total distributable profit for 2016 was RMB 252,735,199.94, with cash dividends accounting for 100% of the profit distribution[130]. - The company has maintained its profit distribution policy in accordance with the shareholder return plan for 2014-2016[125]. - The company has committed to a cash dividend distribution of no less than 10% of the annual distributable profit[153]. - The company plans to review its shareholder return plan at least every three years, considering feedback from independent directors and public investors[154]. Operational Efficiency and Quality Management - The company emphasizes the importance of maintaining a complete quality system to meet the stringent demands of multinational pharmaceutical companies, having successfully passed multiple audits from international regulatory bodies such as the FDA and TGA[9]. - The company has established a comprehensive cGMP quality management system, with three subsidiaries passing FDA audits, two with "zero defects"[50]. - The company has made significant progress in core technologies, including the development of modular continuous reaction devices[61]. - The company has developed a complete supply chain for pharmaceutical raw materials, enhancing market competitiveness[53]. - The company has successfully expanded its CMO business to cover the entire chain of new drug raw materials, increasing operational efficiency and profitability[59]. Employee and Talent Management - The company has established various talent incentive mechanisms to retain core technical personnel, which is crucial for maintaining its competitive edge in the pharmaceutical outsourcing industry[12]. - The company has a workforce of 2,040 employees, with 834 in R&D and QA roles, accounting for 40.88% of total staff[57]. - R&D personnel increased to 834, a growth of 31.13% from 636 in 2015[84]. Social Responsibility and Sustainability - The company actively engages in social responsibility, including establishing scholarships and supporting underprivileged individuals[193]. - The company has implemented sustainable development practices, optimizing pharmaceutical processes to reduce waste and energy consumption[193].