Core Viewpoint - The dispute between Aimeike and Jiangsu Wuzhong regarding the exclusive agency rights for AestheFill has escalated, with Aimeike asserting legal grounds for terminating the agreement due to alleged violations by Jiangsu Wuzhong and its affiliates [1][3][4]. Group 1: Company Actions and Responses - Aimeike claims that Jiangsu Wuzhong's subsidiary, Datou Medical, has transferred its exclusive distribution rights to its controlling shareholder, Wu Zhongmei, which violates the exclusive distribution agreement [1][3]. - Aimeike emphasizes that the termination of the agreement with Datou Medical is legally justified and will rely on judicial rulings for any disputes [1]. - Aimeike refutes allegations of supply delays, stating that the last shipment to Datou Medical occurred in mid-July and that supply to the Chinese market has slightly increased compared to the same period last year [1][2]. Group 2: Jiangsu Wuzhong's Position - Jiangsu Wuzhong disputes Aimeike's claims, asserting that Datou Medical has not transferred agency rights and that the exclusive agency agreement does not allow for termination based on administrative penalties against related parties [4]. - Jiangsu Wuzhong accuses Aimeike of intentionally delaying shipments to Datou Medical, which has led to product shortages and harmed consumer rights [4]. - Jiangsu Wuzhong's official statement claims that Aimeike is abusing its market position to disrupt the supply chain, which contradicts the spirit of the contract [4]. Group 3: Market Reactions - Following the announcement of the dispute, Jiangsu Wuzhong's stock price fell to 1.62 yuan per share, a decline of 4.71%, with a market capitalization of 1.154 billion yuan [6]. - In contrast, Aimeike's stock rose to 186.83 yuan per share, an increase of 0.99%, with a market capitalization of 56.533 billion yuan [6].

Group 1 - The article provides an overview of the Chinese medical beauty industry, highlighting key listed companies and their performance metrics [1][5][9] - Major players in the industry include Aimeike, Huaxi Biological, and Haohai Biological, with Aimeike maintaining the highest market share in the sodium hyaluronate filler market since 2018 [3][5] - The industry is characterized by a diverse supply chain, with upstream raw material manufacturers, midstream medical institutions, and downstream consumers [1][7] Group 2 - In 2024, Aimeike reported a revenue of 30.26 billion, while Huaxi Biological achieved 53.71 billion, indicating strong performance among leading companies [5][10] - The article notes that Aimeike has a gross profit margin exceeding 90%, outperforming other companies in the sector [9][10] - Companies are focusing on R&D innovation and brand building to enhance market competitiveness and meet evolving consumer demands [11][13] Group 3 - The geographical distribution of companies shows a concentration in coastal regions, particularly in major cities like Beijing, Shanghai, and Guangzhou, which host top research institutions and production companies [7] - Companies like Huadong Pharmaceutical and Huaxi Biological primarily focus on domestic sales, while others like Langzi and Huakan have diversified regional strategies [9][10] - Future plans for companies include enhancing R&D capabilities, expanding production projects, and improving customer service to create a win-win ecosystem [11][13]

Core Viewpoint - The termination of the exclusive distribution agreement between Regen and Datou Medical is expected to significantly impact the sales and profits of *ST Suwu's medical aesthetics segment, as it will lose the exclusive rights to sell the AestheFill product in mainland China [1][4]. Group 1: Company Actions - On July 18, 2025, Regen sent a termination letter to Datou Medical, revoking its status as the exclusive distributor for the AestheFill product in mainland China [1][3]. - Following the termination, Datou Medical is prohibited from conducting any business activities as the exclusive distributor and will not be able to place any further orders with Regen [3][4]. - *ST Suwu has initiated a response plan upon receiving the termination letter and is prepared to take legal action if necessary to protect its rights [5]. Group 2: Financial Impact - In 2024, AestheFill generated sales revenue of 326 million yuan, accounting for 20.42% of *ST Suwu's total revenue, with a gross profit of 269 million yuan, representing 34.80% of the company's gross profit [4]. - In the first quarter of 2025, AestheFill sales revenue reached 113 million yuan, making up 35.55% of the company's revenue, with a gross profit of approximately 92.44 million yuan, which is 45.77% of the total gross profit [4]. - The loss of exclusive distribution rights is expected to lead to a significant decline in revenue and profit for the medical aesthetics segment in the second half of 2025 [4]. Group 3: Background Information - The exclusive distribution agreement was originally signed between REGEN and Datou Medical, with the latter acquiring exclusive rights to AestheFill in mainland China in August 2022 [2]. - The agreement was violated by Datou Medical, which allegedly transferred the exclusive distribution business to its controlling shareholder, Jiangsu Wuzhong Meisheng Biotechnology Co., Ltd., leading to the termination [3].

Core Viewpoint - The dispute between Jiangsu Wuzhong and Aimeike over the exclusive agency rights for the AestheFill product highlights the intense competition in the medical aesthetics industry, particularly regarding the popular "childlike" injection products [1][33]. Group 1: Company Disputes - Jiangsu Wuzhong and Aimeike are involved in a conflict over the exclusive distribution rights of the AestheFill product, with Aimeike's subsidiary REGEN Biotech, Inc. sending a termination notice to Jiangsu Wuzhong's subsidiary, Datou Medical [1][2]. - Datou Medical was granted exclusive agency rights for AestheFill in China until August 28, 2032, but allegations have arisen regarding the transfer of these rights to Jiangsu Wuzhong's controlling shareholder [6][7]. - Jiangsu Wuzhong claims that the termination notice's reasons are factually incorrect and asserts that the exclusive distribution agreement remains legally binding [25][32]. Group 2: Financial Implications - Jiangsu Wuzhong is facing significant financial challenges, including a projected net loss of approximately 60 million to 40 million yuan for the first half of 2025 [26]. - The AestheFill product has been a key driver for Jiangsu Wuzhong's financial recovery, with sales revenue from AestheFill contributing significantly to the company's overall income [28][30]. - Aimeike's revenue from its injection products, including its own childlike injection, has shown growth, indicating that regaining AestheFill's agency rights could further enhance its financial performance [30]. Group 3: Industry Context - The medical aesthetics market is becoming increasingly competitive, with multiple players entering the field, including cosmetic companies and new entrants like JD Health [36][37]. - The dispute reflects broader trends in the industry, where companies are vying for market share in the lucrative childlike injection segment, which has seen a surge in demand [33][36]. - The outcome of this dispute will likely impact the market positions and future prospects of both Jiangsu Wuzhong and Aimeike within the medical aesthetics sector [32][33].

Core Viewpoint - The termination of the exclusive distribution agreement for the AestheFill product between *ST Suwu and Aimeike significantly impacts *ST Suwu's financial stability, as this product accounts for a substantial portion of its revenue and profit [2][6]. Group 1: Company Actions and Reactions - *ST Suwu received a termination notice from Aimeike regarding the exclusive distribution rights for AestheFill, which is critical to its revenue stream [2][3]. - Aimeike's acquisition of Regen and subsequent actions to reclaim distribution rights indicate a strategic move to consolidate control over high-margin products [2][4]. - In response to the termination, *ST Suwu's subsidiary, Datou Medical, is pursuing legal action to contest the termination and is considering reporting Aimeike's actions to regulatory authorities [3][4]. Group 2: Financial Implications - AestheFill contributed approximately 3.26 billion yuan to *ST Suwu's revenue in 2024, accounting for about 20% of total revenue, and over 2.69 billion yuan in gross profit, representing more than one-third of the company's profits [5][6]. - In the first quarter of 2025, AestheFill generated 1.13 billion yuan in sales and 0.92 billion yuan in gross profit, making up 35.55% and 45.77% of the company's respective totals [5][6]. - The loss of exclusive distribution rights is expected to lead to a significant decline in *ST Suwu's medical aesthetics segment revenue and profit in the latter half of the year [6]. Group 3: Market Dynamics - The competitive landscape for aesthetic products in China includes seven licensed products, with AestheFill being a key player among both imported and domestic offerings [5]. - Aimeike and *ST Suwu are both targeting the regenerative injection market, indicating a direct competition for market share in high-growth segments [4][5]. - The market for AestheFill is particularly strong in China, where it has achieved record sales, highlighting the importance of maintaining distribution rights for both companies [6].

江苏吴中表示，根据《独家代理权协议》的明确约定，达透医疗拥有AestheFill产品在中国境内的独家 代理权，有效期至2032年8月28日；且Regen承诺达透医疗前述独家代理权不存在任何法律及事实上的 障碍，有关协议有效期内不存在被取消、终止的风险。上述独家代理权协议签署后，达透医疗通过于 2024年1月取得AestheFill相关产品在中国大陆的销售许可，之后，借由其自身和其关联方的销售渠道和 资源，AestheFill相关产品在中国大陆实现了稳定且持续增长的销售额。 2024年度，AestheFill销售收入为3.26亿元，占江苏吴中营业收入的20.42%，毛利2.69亿元，占公司毛利 的34.80%；2025年一季度AestheFill销售收入为1.13亿元，占公司营业收入的35.55%，毛利9243.51万 元，占公司毛利的45.77%。 童颜针AestheFill代理权生变。7月21日晚，江苏吴中医药发展股份有限公司（股票简称：*ST苏吴，以 下简称"江苏吴中"）发布公告宣布，Regen Biotech Inc.（以下简称"Regen"）于2025年7月18日晚间以邮 件方式向公司控股孙公司达透医 ...

Core Viewpoint - Jiangsu Wuzhong (ST Suwu) faces a significant setback as its subsidiary, Datou Medical, receives a termination notice from Regen Biotech, ending their exclusive distribution agreement for AestheFill in mainland China, which may lead to a loss of market position and revenue [2][11]. Group 1: Company Developments - Jiangsu Wuzhong's subsidiary, Datou Medical, had secured exclusive rights for AestheFill in August 2022, with expectations of significant revenue contributions [5][6]. - AestheFill was projected to generate substantial profits, contributing 3.26 billion yuan in sales and 2.69 billion yuan in gross profit for Jiangsu Wuzhong in 2024 [6]. - Following the termination notice, Jiangsu Wuzhong's stock plummeted by 5.03%, reducing its market capitalization to 1.211 billion yuan [3]. Group 2: Market Context - The aesthetic medicine market, particularly the "童颜针" (youthful needle) segment, is rapidly growing, with the market size approaching 600 million yuan in 2023 [16]. - Increased competition in the market is evident, with multiple products receiving approval, intensifying the struggle for market share [16]. - The loss of AestheFill's distribution rights could significantly impact Jiangsu Wuzhong's revenue and market strategy in the aesthetic sector [16]. Group 3: Legal and Strategic Responses - Jiangsu Wuzhong has initiated a response plan and is in active communication with Regen, considering legal action to protect its interests [11][13]. - The company has publicly condemned Regen's unilateral termination of the agreement, asserting that it violates the contractual spirit and could disrupt market order [11][13].

Core Viewpoint - The medical aesthetics industry is undergoing a significant restructuring of its agency rights, highlighted by the recent dispute between REGEN and *ST Suwu over the exclusive agency rights for the injection product Aisufei, which has substantial financial implications for both companies [1][4]. Financial Impact - Aisufei, known as the "youthful needle," generated sales of 326 million yuan in its first year of launch in 2024, with a gross profit of 269 million yuan [1]. - Following the announcement of regulatory penalties against *ST Suwu for financial misconduct, the company's stock price has dropped significantly, losing over 600 million yuan in market value [7]. - In contrast, despite facing growth pressures, Aimeike's stock price increased by 3.85% during the same period, reflecting investor confidence in its fundamentals [7]. Legal and Regulatory Context - The regulatory penalties against *ST Suwu, including a 10-year ban for its chairman, triggered the agency rights dispute, as REGEN cited breaches of contract due to the company's illegal activities [4][6]. - The legal interpretation of the exclusive agency agreement is central to the dispute, with *ST Suwu arguing that there was no transfer of rights, while REGEN claims that the reputation damage from *ST Suwu's actions justifies contract termination [7]. Market Dynamics - The change in agency rights is leading to a rapid reshuffling of distribution channels, with REGEN's subsidiary now taking over the distribution of Aisufei [8]. - Aimeike plans to adopt a direct sales model, enhancing its control over pricing and service standards, which is crucial for maintaining the product's premium positioning [8]. - The market for regenerative injectables is expanding at a compound annual growth rate of 29%, indicating a significant growth opportunity for companies that can effectively navigate the changing landscape [9]. Industry Transformation - The dispute reflects a broader shift in the medical aesthetics industry from a loosely regulated agency model to a more integrated and compliant operational structure [6][9]. - The loss of the medical aesthetics segment poses a challenge for *ST Suwu, which must find ways to sustain its listing status amid declining market support [9].

Core Viewpoint - The article discusses the termination of the exclusive agency agreement for the "Tian Yan Needle" product, Aisufei, between Aimeike and *ST Suwu, following *ST Suwu's recent regulatory penalties for revenue inflation and potential delisting risks [2][3]. Group 1: Company Actions - Aimeike's subsidiary REGEN has decided to reclaim the exclusive agency rights for Aisufei in China, previously held by *ST Suwu's subsidiary Datou Medical [2][3]. - REGEN's global market head stated that the termination is a measure to protect legitimate rights, rejecting collaboration with a company involved in fraudulent activities [3][9]. - Following the termination, Aimeike plans to consider direct sales of Aisufei in mainland China [3][15]. Group 2: Regulatory Context - *ST Suwu was recently penalized by the China Securities Regulatory Commission (CSRC) for inflating revenue and may face forced delisting [1][3]. - The CSRC's investigation revealed multiple violations by *ST Suwu, including undisclosed related-party transactions and revenue inflation [7][9]. Group 3: Financial Implications - Aisufei is projected to generate significant revenue, with an expected sales income of 326 million yuan and a gross profit of 269 million yuan in 2024 [2]. - The termination of the agency agreement is likely to lead to a substantial decrease in *ST Suwu's medical aesthetics segment revenue and profit for the second half of the year [13]. Group 4: Market Reactions - As of July 22, Aimeike's stock price increased by 3.85%, reaching a market capitalization of 55.9 billion yuan, while *ST Suwu's stock fell by 5.03%, with a market capitalization of 1.2 billion yuan [16].

Core Viewpoint - Jiangsu Wuzhong (ST Suwu) faces significant challenges as its subsidiary, Datou Medical, loses exclusive distribution rights for AestheFill in mainland China due to a termination notice from Regen Biotech, which may lead to a substantial decline in revenue and profits for the company [1][6]. Company Summary - Jiangsu Wuzhong's subsidiary, Datou Medical, received a termination notice from Regen Biotech, ending its exclusive distribution agreement for AestheFill, a key product in the high-end medical aesthetics market [1][3]. - The exclusive distribution agreement was initially signed in August 2022, granting Datou Medical rights until August 2032, with Regen promising no legal obstacles to the agreement [3]. - AestheFill significantly contributed to Jiangsu Wuzhong's financial recovery, with projected sales of 10 million units in 2024 and a net profit of 70.48 million yuan, marking a 197.97% increase year-on-year [3][4]. - Following the termination notice, Jiangsu Wuzhong's stock fell to 1.7 yuan per share, a 5.03% drop, reducing its market capitalization to 1.211 billion yuan [2]. Industry Summary - The medical aesthetics industry, particularly the "童颜针" (youthful injection) market, is rapidly growing, with the market size approaching 600 million yuan in 2023 [7]. - The competitive landscape is intensifying, with multiple companies vying for market share, including the recent entry of new products and brands [7]. - The loss of AestheFill's distribution rights could significantly impact Jiangsu Wuzhong's position in the medical aesthetics sector, raising concerns about its future growth and market presence [7].