Core Viewpoint - The article discusses the ongoing dispute over the exclusive distribution rights of AestheFill, a popular facial filler product, between ST Suwu and REGEN, which has implications for both companies' financial performance and market positioning [2][3][6]. Summary by Sections Company Background - ST Suwu's medical beauty segment, which began generating revenue in 2022, is expected to be a significant contributor in 2024, with AestheFill projected to generate sales of 3.26 billion yuan [4][22]. - AestheFill has been approved for sale in 34 countries and regions, giving it a competitive edge in the global market [21]. Dispute Overview - The dispute arose when REGEN terminated its exclusive distribution agreement with ST Suwu's subsidiary, Datuo Medical, citing serious breaches of contract [2][6]. - ST Suwu denies any wrongdoing and claims that there was no transfer of distribution rights [7][8]. Financial Implications - The sales discrepancy of 2.3 billion yuan between Datuo Medical's reported revenue and ST Suwu's AestheFill sales figures raises questions about revenue attribution [9]. - ST Suwu's overall revenue for 2024 is projected to decline by 28.6%, with the medical beauty segment's contribution becoming critical [22][23]. Market Reactions - Medical beauty practitioners express concern over potential supply disruptions and the need for clear communication from suppliers regarding the distribution changes [14][16]. - Despite the ongoing dispute, REGEN assures that the supply chain for AestheFill remains intact and operational [15]. Future Outlook - The outcome of the dispute may affect AestheFill's brand positioning and market share, with potential implications for consumer trust and sales [17][20]. - Love Beauty, the parent company of REGEN, aims to leverage AestheFill to enhance its product portfolio and address declining growth rates in its core business segments [20][22].

Core Viewpoint - The announcement from Jiangsu Wuzhong Pharmaceutical Development Co., Ltd. (ST Wuzhong) regarding the termination of the exclusive distribution agreement for AestheFill in mainland China has highlighted a significant dispute involving multiple parties, including REGEN Biotech and Aimeike [2][4]. Company Overview - ST Wuzhong's subsidiary, Datuo Medical, received a termination notice from REGEN, which has been acquired by Aimeike, leading to the withdrawal of Datuo Medical's exclusive rights to distribute AestheFill, a popular facial filler in China [2][3]. - AestheFill, developed by REGEN, is a medical aesthetic injection that stimulates collagen regeneration to improve skin tightness and reduce wrinkles [3]. Financial Impact - In 2024, AestheFill's sales in China reached 326 million yuan, accounting for approximately 20% of ST Wuzhong's total revenue [4][6]. - Datuo Medical reported a revenue of 96 million yuan with a gross profit of 37 million yuan, marking its first appearance in ST Wuzhong's significant subsidiaries list [6]. - There is a discrepancy of 230 million yuan between Datuo Medical's reported revenue and AestheFill's sales figures, raising questions about revenue attribution [6]. Legal and Compliance Issues - Aimeike's reasons for terminating the agreement include allegations of Datuo Medical transferring its rights to its parent company, Wuzhong Meixue, and ST Wuzhong's history of financial misconduct leading to regulatory penalties [5][8]. - ST Wuzhong refuted these claims, asserting that no transfer of rights occurred and that the agreement did not stipulate that administrative penalties would trigger termination [5][8]. Market Dynamics - The dispute over AestheFill's distribution rights has not yet significantly impacted the operations of medical aesthetic institutions, which continue to procure the product from Wuzhong Meixue [9][10]. - Concerns remain regarding potential brand and trademark disputes, especially with the recent change in the registration agent for AestheFill [11]. Strategic Importance - For Aimeike, regaining control over AestheFill aligns with its internationalization strategy and aims to enhance its product portfolio, especially as its core product lines face declining growth rates [12][13]. - AestheFill has been approved in 34 countries, positioning it as a competitive product in the global market [14]. Future Outlook - ST Wuzhong has warned investors that the termination of AestheFill's distribution rights could lead to a significant decline in revenue and profits for its medical aesthetics segment in the second half of the year [15]. - Aimeike has indicated that REGEN's new factory in South Korea will ensure a stable supply of AestheFill to meet global demand, including the Chinese market [15].

Investment Rating - The report maintains an "Overweight" rating for the pharmaceutical and biotechnology industry, expecting the industry index to outperform the market index by over 10% in the next six months [1][40]. Core Insights - The SW pharmaceutical and biotechnology industry outperformed the CSI 300 index, rising by 7.84% from July 11 to July 24, 2025, exceeding the CSI 300's performance by approximately 4.13 percentage points [4][14]. - Most sub-sectors within the industry recorded positive returns during the same period, with the medical research outsourcing and raw materials sectors leading with increases of 14.23% and 9.30%, respectively [4][15]. - Approximately 91% of stocks in the industry achieved positive returns, with notable performers including Borui Pharmaceutical, which saw a weekly increase of 78.98% [16]. Summary by Sections 1. Market Review - The SW pharmaceutical and biotechnology industry outperformed the CSI 300 index, with a rise of 7.84% from July 11 to July 24, 2025, surpassing the CSI 300 by about 4.13 percentage points [14]. - Most sub-sectors recorded positive returns, particularly medical research outsourcing and raw materials, which increased by 14.23% and 9.30%, respectively [15]. - About 91% of stocks in the industry had positive returns, with Borui Pharmaceutical leading at 78.98% [16]. 2. Industry News - The report highlights the ongoing progress of the 11th batch of national drug procurement, with significant updates provided during a government open day event on July 22, 2025 [4][28]. - The announcement of the 11th batch of national drug procurement included a notification for drug information submission, which was highly anticipated [4][28]. 3. Company Announcements - Yekang Pharmaceutical announced that its subsidiary received FDA approval for clinical trials of YKYY029 injection for hypertension treatment [29]. 4. Industry Outlook - The report maintains an "Overweight" rating for the industry, citing a continuous rise in the pharmaceutical and biotechnology sector driven by positive sentiment towards innovative drugs and improved financing data [30]. - The report suggests focusing on investment opportunities within the innovative drug supply chain and highlights several companies across various segments, including medical devices, pharmaceutical commerce, and innovative drugs [30][32].

Core Viewpoint - The medical device sector is showing strong performance, with multiple ETFs related to the sector experiencing gains of over 1% in half a day of trading [1][4]. Group 1: ETF Performance - The medical ETF (512170) recorded a half-day increase of 1.37%, with a total scale of 74.95 billion units and a trading volume of 922 million yuan [4]. - The medical device ETF fund (159797) also saw a half-day increase of 1.38%, with a smaller scale of 130 million units and a trading volume of 11.61 million yuan [6]. - Other ETFs in the medical device sector, such as the medical device ETF (562600) and the medical device index ETF (159898), are also tracking the performance of the sector [6][9]. Group 2: Industry Trends - The regulatory approach in China's medical device sector is shifting from "compliance control" to "innovation-led" development, driven by aging populations and increasing chronic diseases, indicating a dual-driven period of policy and technology [4]. - The core trends in the industry include domestic substitution and technology going abroad [4]. Group 3: Index Composition - The CSI Medical Index includes companies involved in medical devices, medical services, and medical information technology, reflecting the overall performance of listed companies in the medical sector [4][7]. - Major weighted stocks in the CSI Medical Index include Mindray Medical (14.04%), United Imaging Healthcare (9.42%), and Aimeike (4.12%) [8][10].

Core Viewpoint - The medical device sector is experiencing significant growth, with the medical device ETF (159797) showing strong performance and attracting substantial investment, indicating a positive outlook for the industry [1][4]. Group 1: Market Performance - As of July 25, 2025, the CSI All Medical Device Index (H30217) rose by 1.07%, with notable increases in individual stocks such as Kangtai Medical (300869) up 20.03% and Tianzhihang (688277) up 13.81% [1]. - The medical device ETF (159797) saw a peak increase of over 2% during the trading session, currently up 1.13%, marking its eighth consecutive day of gains [1]. - Over the past week, the medical device ETF has accumulated a rise of 4.61% [1]. Group 2: Trading Activity - The medical device ETF recorded a turnover rate of 10.77% during the trading session, with a transaction volume of 11.3369 million yuan, indicating active market participation [1]. - The average daily trading volume for the ETF over the past week was 7.7187 million yuan [1]. Group 3: Fund Inflows and Size - The medical device ETF has seen a net subscription of 7 million shares, marking a continuous inflow of funds for seven days [1][2]. - The latest fund size of the medical device ETF reached 103 million yuan, a new high for the past year [2]. - The total shares of the medical device ETF have reached 130 million, also a new high for the past year [2]. Group 4: Policy and Industry Outlook - The National Healthcare Security Administration recently held a meeting to discuss support for innovative medical devices, highlighting new pricing policies aimed at accelerating the clinical application of high-level technological innovations [4]. - According to CITIC Construction Investment Securities, the medical device sector is expected to see a recovery in valuations and performance, with several companies anticipated to experience high growth in Q3 due to product innovation and international expansion opportunities [4][5]. - The medical device ETF covers core areas such as medical equipment, in vitro diagnostics, and high-value consumables, with the top ten weighted stocks accounting for nearly 46% of the ETF [5].

Summary of Key Points from Conference Call Records Industry Overview - The conference call primarily discusses the medical aesthetics (医美) industry and related companies, including New Oxygen (新氧), Love Beauty (爱美客), and others in the beauty and healthcare sectors. Core Insights and Arguments 1. **New Oxygen's Business Model**: New Oxygen is leveraging standardized projects and private traffic to reduce costs and attract price-sensitive consumers. However, the increasing demand for high-end projects may raise costs for doctors, posing a challenge for the company's long-term strategy [8][9][11]. 2. **Impact of Market Sentiment**: Runben's stock price rebounded nearly 30% due to market sentiment influenced by the outbreak of diseases in Foshan, despite limited actual sales impact [1][3]. 3. **Acquisition Benefits for Love Beauty**: Love Beauty's acquisition of Region and obtaining the agency rights for Isophane in China has significantly boosted its stock price, with expected profit contributions of over 450 million yuan in the coming year [1][20]. 4. **Challenges for Juzi Biotechnology**: Juzi's sales have declined due to public sentiment issues, leading to a drop in valuation. The recovery of sales through influencer marketing will be crucial for its stock price rebound [1][4][31]. 5. **LePu Medical's Performance**: LePu's main business is affected by centralized procurement, but its medical aesthetics segment is progressing well, with expected revenue contributions from new products [1][13]. 6. **Market Dynamics**: The medical aesthetics industry is experiencing increased competition and price wars, driven by the entry of new products and the need for traditional institutions to adapt to New Oxygen's model [10][12]. Additional Important Insights 1. **Digital Transformation in Beauty Sector**: Companies like Beautiful Farm are enhancing business uniformity and customer acquisition costs through digital systems and training, positioning themselves for growth [2][17]. 2. **Emerging Trends in Marketing**: The rise of short videos and live-streaming as marketing channels is reshaping how brands engage with younger consumers, necessitating innovative strategies [6][8]. 3. **Regulatory Changes**: New regulations on advertising may impact smaller brands more significantly than larger listed companies, potentially improving the competitive landscape for established players [23]. 4. **Future Outlook for Companies**: Companies like Beautiful Farm and Love Beauty are expected to see significant growth due to strategic acquisitions and market positioning, while others like Juzi may need to recover from recent setbacks [17][20][31]. This summary encapsulates the key points discussed in the conference call, highlighting the dynamics within the medical aesthetics industry and the performance outlook for various companies involved.

Core Viewpoint - The article discusses the ongoing dispute between Jiangsu Wuzhong and Aimeike over the exclusive distribution rights of the AestheFill product, a popular imported facial filler, highlighting the implications for both companies amid a competitive medical aesthetics market [2][4][44]. Group 1: Dispute Overview - The dispute involves Jiangsu Wuzhong and Aimeike regarding the exclusive distribution rights of AestheFill, with Aimeike's subsidiary REGEN Biotech seeking to terminate the agreement with Jiangsu Wuzhong's subsidiary [4][10]. - Jiangsu Wuzhong claims that the exclusive distribution rights are valid until August 28, 2032, and that the agreement has not been violated [28][40]. - The conflict arises from allegations of business transfer violations and regulatory issues faced by Jiangsu Wuzhong, which could impact the reputation of AestheFill in the Chinese market [10][11]. Group 2: Financial Implications - Jiangsu Wuzhong's stock price fell to a 60-day low following the dispute, while Aimeike's stock price increased, indicating market reactions to the news [6][30]. - AestheFill significantly contributed to Jiangsu Wuzhong's financial turnaround, with sales revenue of approximately 326.41 million yuan in 2024, accounting for 20.42% of the company's total revenue [37][33]. - Aimeike's revenue from its injection products, including AestheFill, was approximately 3.0257 billion yuan in 2024, reflecting a 5.44% increase from the previous year [38]. Group 3: Market Context - The dispute highlights the intensifying competition in the medical aesthetics sector, with multiple players vying for market share, including established cosmetic companies and new entrants [44][46]. - The market has seen a rise in the number of approved facial fillers, with nine products currently available, indicating a growing demand and competition in the sector [45]. - The outcome of the dispute will likely influence the market positions and future prospects of both Jiangsu Wuzhong and Aimeike in the medical aesthetics industry [47].

沪指7月24日上涨0.65%，申万所属行业中，今日上涨的有28个，涨幅居前的行业为美容护理、有色金 属，涨幅分别为3.10%、2.78%。美容护理行业位居今日涨幅榜首位。跌幅居前的行业为银行、通信、 公用事业，跌幅分别为1.42%、0.15%、0.09%。 资金面上看，两市主力资金全天净流入89.13亿元，今日有16个行业主力资金净流入，有色金属行业主 力资金净流入规模居首，该行业今日上涨2.78%，全天净流入资金77.36亿元，其次是非银金融行业，日 涨幅为2.06%，净流入资金为56.44亿元。 美容护理行业资金流向排名 | 代码 | 简称 | 今日涨跌幅（%） | 今日换手率（%） | 主力资金流量（万元） | | --- | --- | --- | --- | --- | | 300896 | 爱美客 | 6.45 | 3.68 | 13655.56 | | 603630 | 拉芳家化 | 10.02 | 7.75 | 8470.57 | | 603605 | 珀莱雅 | 3.15 | 2.76 | 8385.03 | | 688363 | 华熙生物 | 5.65 | 2.03 | 8336.93 | ...

Group 1 - The Shanghai Composite Index rose by 0.65% to close above 3600 points, marking a new high for the year [1] - The medical device ETF (159797) increased by 2.32%, achieving a seven-day consecutive rise and reaching new highs in scale and shares [1] - The medical device ETF has attracted over 13 million yuan in funds over the past six days [1] Group 2 - The National Healthcare Security Administration announced that the selection process for medical supplies will no longer solely rely on the lowest bid, indicating a shift in procurement strategy [3] - In the second half of 2025, the medical device sector is expected to see performance improvements due to inventory clearance and the gradual easing of compliance impacts [3] - The overall procurement scale for new medical devices in China showed a 41% year-on-year increase in the first half of 2025, with specific categories like CT and MR showing significant growth [3] Group 3 - Continuous implementation of equipment renewal policies is expected to drive long-term growth in medical device procurement levels [4] - The medical device and consumables sector is currently valued at historical lows, indicating potential for recovery as market conditions improve [4] - The medical device ETF (159797) covers key areas in the medical device sector, with the top ten weighted stocks accounting for nearly 46% of the fund [4][5]

Core Viewpoint - The dispute between Aimeike and Jiangsu Wuzhong regarding the exclusive agency rights for AestheFill has escalated, with Aimeike asserting legal grounds for terminating the agreement due to alleged violations by Jiangsu Wuzhong and its affiliates [1][3][4]. Group 1: Company Actions and Responses - Aimeike claims that Jiangsu Wuzhong's subsidiary, Datou Medical, has transferred its exclusive distribution rights to its controlling shareholder, Wu Zhongmei, which violates the exclusive distribution agreement [1][3]. - Aimeike emphasizes that the termination of the agreement with Datou Medical is legally justified and will rely on judicial rulings for any disputes [1]. - Aimeike refutes allegations of supply delays, stating that the last shipment to Datou Medical occurred in mid-July and that supply to the Chinese market has slightly increased compared to the same period last year [1][2]. Group 2: Jiangsu Wuzhong's Position - Jiangsu Wuzhong disputes Aimeike's claims, asserting that Datou Medical has not transferred agency rights and that the exclusive agency agreement does not allow for termination based on administrative penalties against related parties [4]. - Jiangsu Wuzhong accuses Aimeike of intentionally delaying shipments to Datou Medical, which has led to product shortages and harmed consumer rights [4]. - Jiangsu Wuzhong's official statement claims that Aimeike is abusing its market position to disrupt the supply chain, which contradicts the spirit of the contract [4]. Group 3: Market Reactions - Following the announcement of the dispute, Jiangsu Wuzhong's stock price fell to 1.62 yuan per share, a decline of 4.71%, with a market capitalization of 1.154 billion yuan [6]. - In contrast, Aimeike's stock rose to 186.83 yuan per share, an increase of 0.99%, with a market capitalization of 56.533 billion yuan [6].