基金管理人在二季报中表示，对内，我们寻找能分享银发经济和国内需求迭代的投资标的，包括但不限于创新药械、CXO、药店等领域；对外，我们挖掘 积极拥抱出海浪潮的公司，包括但不限于医疗耗材和设备、原料药、创新药械等领域。在持有基本面持续向好板块的同时，加大布局业绩有望迎来改善或者 即将见底的板块和个股。我们始终坚持寻找产业周期和企业经营周期共振的公司，希望打造一支能较为稳定战胜业绩基准的产品，并持续拓展认知边界，优 化组合管理能力，为持有人的利益不断努力。 截至7月18日，财通资管医疗保健混合A近三个月复权单位净值增长率为27.15%，位于同类可比基金71/138；近半年复权单位净值增长率为38.72%，位于同 类可比基金73/138；近一年复权单位净值增长率为40.05%，位于同类可比基金68/133。 AI基金财通资管医疗保健混合A（018484）披露2025年二季报，第二季度基金利润2479.39万元，加权平均基金份额本期利润0.1341元。报告期内，基金净值 增长率为12.31%，截至二季度末，基金规模为1.31亿元。 该基金属于偏股混合型基金，长期投资于医药医疗股票。截至7月18日，单位净值为1.2元。基 ...

Core Viewpoint - The AI Fund Huashang Medical Healthcare Industry Stock (008107) reported a profit of 10.4658 million yuan for Q2 2025, with a weighted average profit per fund share of 0.0867 yuan, and a net asset value growth rate of 9.27% during the period [2]. Fund Performance - As of July 18, the fund's unit net value was 1.185 yuan, with a one-year cumulative net value growth rate of 31.43%, the highest among its peers [2]. - The fund's performance over different time frames includes a three-month growth rate of 25.30%, a six-month growth rate of 39.08%, and a three-year growth rate of 5.05% [3]. - The fund's Sharpe ratio over the past three years is 0.0875, ranking 16 out of 46 comparable funds [8]. Fund Management Insights - The fund manager noted that global economic variables in Q2 were primarily influenced by tariff and fiscal policies, with a shift from extreme pessimism to stability in tariff policies [2]. - The domestic economy showed slight overall slowdown, with resilience in the industrial sector and structural differences driven by the "old-for-new" consumption policy [2]. Sector Performance - In Q2, sectors such as military industry, non-ferrous metals, new consumption, innovative drugs, overseas computing power chains, and large finance performed well, indicating a recovery in market sentiment and risk appetite [2]. - Within the pharmaceutical sector, innovative drugs stood out, supported by multiple clinical data releases and significant business development (BD) agreements [2]. Fund Holdings - As of Q2 2025, the fund's total assets amounted to 139 million yuan, with the top ten holdings including companies like Innovent Biologics, WuXi AppTec, and Mindray Medical [15][18].

Summary of Conference Call Records Industry Overview - The conference call discusses the **Chinese innovative drug development industry**, highlighting improvements in the sector's profitability and investment landscape [1][2][20]. Key Points and Arguments 1. **Profitability Cycle**: Innovative drug companies are entering a profitability cycle, with leading firms like **Innovent Biologics** and **BeiGene** expected to exceed performance expectations in the second half of the year [1][3]. 2. **Supportive Factors**: The market for innovative drugs is anticipated to continue its upward trend, supported by policy changes, industry developments, and strong performance metrics. Key policy changes include the acceleration of clinical licensing from 60 days to 30 days and the upcoming implementation of commercial insurance directories [3][21]. 3. **Investment Opportunities**: The call recommends focusing on companies such as **Kangchen Pharmaceutical**, **One Biotech**, **Innovent Biologics**, **3SBio**, and **China Biologic Products** for their promising performance in the A-share and H-share markets [4][5]. 4. **CXO and Life Sciences Services**: The CXO (Contract Research and Manufacturing Organization) and life sciences services sector is experiencing growth, particularly in overseas markets where CDMO companies have seen order growth of over 15% [6][22]. 5. **Funding Sources**: The funding sources for innovative drug development in China have diversified, with business development (BD) upfront payments becoming a significant source of capital, surpassing traditional investment levels [7][22]. 6. **Stem Cell Industry**: Both China and the U.S. have made significant advancements in the stem cell industry, with approvals for stem cell products aimed at treating graft-versus-host disease [10][11]. 7. **IVD Industry Trends**: The IVD (in vitro diagnostics) industry has stabilized after a period of decline, with expectations of a 10% growth in diagnostic volumes next year [16][17]. 8. **AI in Healthcare**: The integration of AI in healthcare is still in its nascent stages, with no significant commercialized products yet, but ongoing developments are being monitored [18]. 9. **Pharmacy Industry Dynamics**: The pharmacy sector is facing challenges due to regulatory scrutiny, which may lead to increased industry consolidation [19]. Additional Important Insights - **Market Recovery**: The innovative drug IPO market in Hong Kong is showing signs of recovery, with a notable increase in the number of IPOs and fundraising amounts [21][22]. - **Performance Metrics**: Companies like **Guan Li Tonghua** and **Lianbang Pharmaceutical** are expected to perform well in their insulin business, indicating strong market potential [14]. - **Weight Loss Drugs**: **Kangyuan Pharmaceutical** has two promising weight loss drugs that are gaining attention due to their favorable safety data [13]. This summary encapsulates the key insights and developments discussed in the conference call, providing a comprehensive overview of the current state and future outlook of the innovative drug development industry in China.

2025 年 07 月 20 日 投资评级：看好（维持） 医药生物 行业走势图 -24% -12% 0% 12% 24% 36% 2024-07 2024-11 2025-03 医药生物 沪深300 数据来源：聚源 相关研究报告 《CXO 龙头中报业绩超预期，重点关 注板块后续行情 — 行 业 周 报 》 -2025.7.13 《艾伯维收购 Capstan，加码体内 CAR-T—行业周报》-2025.7.6 《多款减肥药亮相 2025 ADA，重点关 注 AMYR 与 ActRII 靶点—行业周报》 -2025.6.29 集采政策明确优化，继续推荐制药板块性机会 ——行业周报 | 余汝意（分析师） | 刘艺（联系人） | 聂媛媛（联系人） | | --- | --- | --- | | yuruyi@kysec.cn | liuyi1@kysec.cn | nieyuanyuan@kysec.cn | | 证书编号：S0790523070002 | 证书编号：S0790124070022 | 证书编号：S0790124050002 | 集采政策持续优化，仿创 pharma 有望估值重塑 集采政策优化基调明确， ...

Group 1 - The top three companies with the highest short positions are WuXi AppTec (02359), CATL (03750), and COSCO Shipping Holdings (01919), with short ratios of 23.99%, 17.39%, and 14.14% respectively [1][2] - The companies with the largest increase in short positions are Giant Biogene (02367), WuXi AppTec (02359), and Henderson Land Development (00012), with increases of 2.05%, 1.43%, and 1.41% respectively [1][2] - The companies with the largest decrease in short positions are SF Holding (06936), Far East Horizon (03360), and Jiumaojiu International Holdings (09922), with decreases of -1.94%, -1.22%, and -1.18% respectively [1][3] Group 2 - The top ten companies with the highest short ratios include Ganfeng Lithium (01772) at 13.09%, Xiexin Technology (03800) at 12.57%, and Shandong Gold (01787) at 12.35% [2] - The companies with the largest increase in short ratios also include Fuyou Glass (06865) at 12.07% and Tigermed (03347) at 9.81% [2] - The companies with the largest decrease in short ratios include Vanke Enterprise (02202) at 11.38% and Green Leaf Pharmaceutical (02186) at 11.96% [3][4]

Group 1 - Senyuan Electric signed a strategic cooperation agreement with Xuchang Digital Supply Chain Management Co., aiming for annual business cooperation not exceeding 500 million yuan over 36 months [1] - CICC's subsidiary, CICC Wealth, reported a net profit of 987 million yuan for the first half of the year, with total assets of 193.37 billion yuan [2] - Shuangjie Electric expects a net profit of 100 million to 120 million yuan for the first half of the year, representing a year-on-year increase of 16.03% to 39.23% [3][4] - Shentong Technology reported a net profit of 64.28 million yuan for the first half of the year, a year-on-year increase of 111.09% [5] - Suqian Nongfa's net profit for the first half of the year decreased by 27.72% to 213 million yuan [6] Group 2 - Fuan Pharmaceutical expects a net profit decline of 39.95% to 53.81% for the first half of the year, estimating between 100 million to 130 million yuan [8] - Xingwang Yuda anticipates a net loss of 11 million to 21 million yuan for the first half of the year [9] - Pulaike received a new veterinary drug registration certificate for a vaccine aimed at preventing chicken diseases [10] - Yuandong Biological's ephedrine injection received a drug registration certificate for treating low blood pressure during anesthesia [11] - Suqian Liansheng's subsidiary obtained two invention patent certificates [12] Group 3 - Oke Technology signed a 176 million yuan equipment order with Jiangxi Tianhong New Materials [13] - Publishing Media announced the resignation of its chief accountant due to work changes [15] - Zhongxin Co. plans to use 40 million yuan of idle funds for cash management [16] - Huiyun Titanium plans to use up to 58 million yuan of idle convertible bond funds for cash management [18] - Haineng Technology intends to apply for a credit facility of up to 200 million yuan from a bank [20] Group 4 - Jiabiou expects a net profit increase of 57.61% for the first half of the year, estimating around 107 million yuan [21] - Nanjing Gaoke reported a 1185% year-on-year increase in contract sales area for the second quarter [22] - Shuguang Co. received approval for a specific stock issuance application [23] - Huadong Pharmaceutical's subsidiary received approval for a clinical trial of a new drug targeting advanced solid tumors [23] - Quicheng Co. plans to invest 900 million yuan in two new projects [25] Group 5 - Shenlian Biological's vaccine for avian adenovirus received a new veterinary drug registration certificate [26] - Rike Chemical signed a strategic cooperation framework agreement with Dongming Petrochemical [28] - Jincheng Pharmaceutical's subsidiary received a renewed tobacco production license [29] - Magmi Te's stock issuance application was accepted by the Shenzhen Stock Exchange [29] - Zhongyin Securities received approval to issue bonds totaling up to 14 billion yuan [29] Group 6 - Hewei Electric's executives plan to reduce their holdings by a total of 2.24% of the company's shares [44] - Guo Wang Xintong reported a net profit of 266 million yuan for the first half of the year, a decrease of 10.82% [45] - Guo Wang Xintong's subsidiary won a 966 million yuan tender from the State Grid [46] - Jicheng Electronics won contracts worth approximately 83.79 million yuan from the State Grid [48] - Helen Piano is planning a change of control, leading to a temporary stock suspension [48]

Market Overview - The Hang Seng Index closed at 24,518, down 0.08% for the day but up 22.13% year-to-date[3] - The Hang Seng China Enterprises Index ended at 8,861, decreasing by 0.09% daily and up 21.44% year-to-date[3] - The Hang Seng Tech Index rose by 0.56% to 5,418, with a year-to-date increase of 21.95%[3] Sector Performance - Biopharmaceutical stocks surged, with Kanghua rising 14.5% and other companies like Kangfang Bio and Baiji Shenzhou increasing over 10%[9] - Major tech stocks showed mixed results, with Meituan up over 1% while Baidu fell over 3%[9] - Li Auto's stock increased by over 9% following the announcement of pre-orders for its new model priced between 350,000 to 400,000 RMB[9] U.S. Market Highlights - The Nasdaq Composite rose by 0.74%, the S&P 500 increased by 0.54%, and the Dow Jones Industrial Average gained 0.52%, all reaching new closing highs[9] - Nvidia's stock rose by 0.95%, while Microsoft increased by 1.20%, both achieving historical closing highs[9] - Netflix reported a net profit of $3.125 billion for Q2 2025, a 45.6% year-on-year increase, and raised its revenue and profit margin guidance for the year[9] Economic Indicators - U.S. retail sales rose by 0.6% in June, exceeding expectations, primarily driven by a rebound in auto sales[12] - The U.S. unemployment claims fell to 221,000, indicating a resilient job market despite a slowdown in hiring[12] - U.S. tariff revenues surged to $87.2 billion in the first half of the year, with June alone accounting for $26.6 billion, four times the usual level[12]

Core Viewpoint - China National Pharmaceutical Group (中生制药) has acquired the innovative drug company Lixin Pharmaceutical (礼新医药) for $950 million (approximately 6.8 billion RMB), with the deal being characterized as a high-value acquisition despite initial market skepticism regarding Lixin's product pipeline [1][4]. Group 1: Acquisition Details - The acquisition was completed in a short span of two months, indicating strong mutual interest from both parties [1][4]. - The net cost of the acquisition is effectively reduced to $500 million after accounting for Lixin's cash reserves of $450 million and other operational expenses [4]. - Lixin Pharmaceutical has a strong track record, having raised significant funding and established partnerships with major pharmaceutical companies like AstraZeneca and Merck [1][5]. Group 2: Financial Implications - Lixin's valuation during its last funding round was approximately 2.9 billion RMB, and the acquisition price reflects a significant return for early investors, exceeding 100% [4][5]. - The acquisition is expected to enhance China National Pharmaceutical's revenue from innovative products, which is projected to rise from 16% in 2018 to 42% by 2024 [9]. Group 3: Product Pipeline and Development - Lixin has developed a robust pipeline with eight self-researched innovative drugs currently in clinical trials, including promising candidates like CCR8 monoclonal antibody LM-108 and CLDN18.2 ADC drug LM-302 [6][11]. - The acquisition will bolster China National Pharmaceutical's capabilities in large molecule drug development, particularly in oncology, where it has 36 candidates in clinical development [9][10]. Group 4: Strategic Positioning - The acquisition aligns with China National Pharmaceutical's strategy to transition from traditional pharmaceutical operations to a more innovation-driven model, aiming to launch five innovative products annually over the next three years [9]. - Lixin's integration is seen as a strategic move to enhance R&D capabilities and accelerate the commercialization of innovative drugs in a competitive market [8][11].

Market Performance - The Shanghai Composite Index rose by 0.37% to 3516.83 points, while the Shenzhen Component increased by 1.43% and the ChiNext Index gained 1.76%[1] - The Hong Kong Hang Seng Index fell by 0.08% to 24498.95 points, with the Hang Seng Tech Index up by 0.56% and the Hang Seng China Enterprises Index down by 0.09%[1] Legislative Developments - The U.S. Congress passed a stablecoin bill, paving the way for broader use of this technology in finance[9] - The U.S. Department of Commerce proposed a 93.5% anti-dumping tariff on Chinese graphite, a key material for batteries, which is expected to impact the electric vehicle supply chain[9][13] Economic Indicators - U.S. retail sales rebounded in June, increasing by 0.6%, surpassing economists' expectations, with auto sales being a significant contributor to this growth[13] - In June, China's exports grew by 5.8% year-on-year, while imports increased by 1.1%, resulting in a trade surplus of $114.77 billion[18]

Core Viewpoint - The AI Fund for Healthcare Industry Mixed A/B reported a profit of 16.87 million yuan for Q2 2025, with a fund size of 660 million yuan and a net value growth rate of 2.59% [2][14]. Fund Performance - As of July 17, the fund's unit net value was 1.628 yuan, with a three-month growth rate of 8.32%, a six-month growth rate of 10.97%, a one-year growth rate of 12.27%, and a three-year growth rate of -29.52% [2][3]. - The fund's Sharpe ratio over the past three years was -0.2967, ranking 96 out of 105 comparable funds [7]. - The maximum drawdown over the past three years was 43.62%, with the largest single-quarter drawdown occurring in Q1 2024 at 26.26% [10]. Investment Strategy - The fund manager emphasized two main focus areas: 1) Industry logic and cost-effectiveness, with a higher demand for certainty and future potential in stock selection, especially in the A-share market; 2) Directions with improvement expectations, including previously underappreciated areas in the healthcare sector that may see revaluation [2]. - The fund maintained an average stock position of 86.75% over the past three years, peaking at 94.16% in Q1 2024 and dropping to 67.75% in Q1 2025 [13]. Top Holdings - As of Q2 2025, the fund's top ten holdings included companies such as Heng Rui Medicine, San You Medical, WuXi AppTec, and others [17].