Investment Rating - The report maintains an "Overweight" rating for the pharmaceutical and biotechnology industry, expecting the industry index to outperform the market index by over 10% in the next six months [1][40]. Core Insights - The SW pharmaceutical and biotechnology industry outperformed the CSI 300 index, rising by 7.84% from July 11 to July 24, 2025, exceeding the CSI 300's performance by approximately 4.13 percentage points [4][14]. - Most sub-sectors within the industry recorded positive returns during the same period, with the medical research outsourcing and raw materials sectors leading with increases of 14.23% and 9.30%, respectively [4][15]. - Approximately 91% of stocks in the industry achieved positive returns, with notable performers including Borui Pharmaceutical, which saw a weekly increase of 78.98% [16]. Summary by Sections 1. Market Review - The SW pharmaceutical and biotechnology industry outperformed the CSI 300 index, with a rise of 7.84% from July 11 to July 24, 2025, surpassing the CSI 300 by about 4.13 percentage points [14]. - Most sub-sectors recorded positive returns, particularly medical research outsourcing and raw materials, which increased by 14.23% and 9.30%, respectively [15]. - About 91% of stocks in the industry had positive returns, with Borui Pharmaceutical leading at 78.98% [16]. 2. Industry News - The report highlights the ongoing progress of the 11th batch of national drug procurement, with significant updates provided during a government open day event on July 22, 2025 [4][28]. - The announcement of the 11th batch of national drug procurement included a notification for drug information submission, which was highly anticipated [4][28]. 3. Company Announcements - Yekang Pharmaceutical announced that its subsidiary received FDA approval for clinical trials of YKYY029 injection for hypertension treatment [29]. 4. Industry Outlook - The report maintains an "Overweight" rating for the industry, citing a continuous rise in the pharmaceutical and biotechnology sector driven by positive sentiment towards innovative drugs and improved financing data [30]. - The report suggests focusing on investment opportunities within the innovative drug supply chain and highlights several companies across various segments, including medical devices, pharmaceutical commerce, and innovative drugs [30][32].

Summary of Key Points from the Conference Call Industry Overview - **Industry Focus**: The conference call primarily discusses the healthcare sector in China, particularly the medical technology (Medtech), in vitro diagnostics (IVD), retail pharmacies, hospitals, vaccines, and insulin markets [1][2]. Core Insights and Arguments Medtech - **Key Areas of Focus**: 1. Progress of capital equipment value-based procurement (VBP) and the trade-in policy [1] 2. Channel destocking trends [1] 3. Import substitution trends post-VBP, including intraocular lenses (IOLs) and IVD [1] - **VBP Impact**: The June bidding value data showed a year-on-year growth rate of 49%, but a month-on-month decline of 3%, indicating lower unit prices due to VBP [10]. IVD Market - **Weak Demand**: The IVD sector continues to face challenges, with a projected 20% year-on-year decline in the CLIA reagent market size for 2025 [19]. - **AmoyDx Performance**: AmoyDx is expected to grow against the trend due to its strong presence in compliant in-hospital sales channels, benefiting from the anti-corruption campaign [21]. Insulin Market - **Domestic Substitution**: The insulin industry has seen significant growth, particularly for insulin analogs from companies like Gan & Lee and THDB, which reported rapid revenue growth in 1Q25 [22]. Retail Pharmacies - **Market Pressure**: Retail pharmacies are under pressure due to strict reimbursement policies and weak consumer spending. However, there is a potential market-clearing trend expected by year-end [31]. Hospitals - **New Product Feedback**: Hospitals are seeing new product introductions, such as the new version of SMILE surgery and new PIOL products, which are expected to drive consumption recovery [1]. Vaccine Market - **Anti-Corruption Campaign**: The ongoing anti-corruption campaign within the CDC system is impacting vaccine demand and distribution channels [1]. Financial Performance and Estimates Earnings Revisions - **Mindray**: Annual earnings estimates revised down by 2.1% to 5.0% for 2025E-27E due to industry headwinds in medical equipment and IVD [2][37]. - **United Imaging**: Revenue and earnings forecasts adjusted down to reflect lower-than-expected bidding data [39]. - **SNIBE**: Earnings estimates revised down by 1.4% to 7.1% for 2025E-27E due to policy headwinds in the IVD sector [40]. Revenue Growth Expectations - **High Growth Companies**: THDB and Gan & Lee are expected to achieve the highest revenue growth due to a low base from VBP renewal in 2Q24 [6]. - **Mindray's Decline**: Mindray's China business is expected to decline by 26% year-on-year in 2Q25 due to IVD weakness [9]. Other Important Insights - **Trade-in Policy Concerns**: The trade-in stimulus fund is expected to run out, leading to a decline in applications and a reduced stimulus effect in the second half of 2025 [10]. - **Market Dynamics**: The healthcare market is experiencing a shift with increasing government support for procurement and a focus on innovative products [47][48]. Conclusion - The healthcare sector in China is facing various challenges, including policy headwinds, weak demand in certain segments, and the impact of ongoing reforms. However, there are also opportunities for growth, particularly in innovative products and domestic substitution trends. Companies like AmoyDx, Gan & Lee, and THDB are positioned to benefit from these trends, while others like Mindray and SNIBE are facing headwinds that may impact their performance in the near term.

Group 1 - The core index of the China Securities Index for Food and Major Consumer Goods Retail has shown a recent upward trend, with a 4.43% increase over the past month, a 0.49% increase over the past three months, and a year-to-date decline of 3.88% [1] - The index is composed of listed companies in the food and drug retail sector, reflecting the overall performance of these companies, with a base date of December 31, 2004, set at 1000.0 points [1] - The top ten weighted companies in the index include Yonghui Supermarket (6.49%), Digital China (6.34%), Shanghai Pharmaceuticals (4.65%), Yifeng Pharmacy (4.23%), and others [1] Group 2 - The market share of the index's holdings is divided between the Shanghai Stock Exchange (53.16%) and the Shenzhen Stock Exchange (46.84%) [1] - In terms of industry composition, the index shows that pharmaceutical commerce accounts for 44.64%, supermarkets and convenience stores for 20.60%, specialty retail for 20.32%, and department stores for 14.44% [2] - The index samples are adjusted biannually, with adjustments occurring on the next trading day after the second Friday of June and December each year [2]

Investment Rating - The report maintains a "Recommended" investment rating for the pharmaceutical industry as of July 20, 2025 [1] Core Insights - The establishment of a positive innovation cycle is driving value enhancement in the pharmaceutical sector, particularly through overseas collaborations and the increasing recognition of the value of PD-1/VEGF dual antibodies [2] - The focus on tri-antibodies is rising, with significant potential for competition in first-line treatments, as evidenced by recent collaborations and promising clinical data [3] - The trend towards more effective and scientifically-backed weight loss solutions is evident, with GLP-1 drugs projected to generate over $50 billion in global sales in 2024, significantly boosting capital interest [5] - The trend in autoimmune drug development is shifting towards innovative therapies, with notable advancements in dual-target fusion proteins [6] - The approval of Vuxinib (伏欣奇拜单抗) marks a significant milestone in biological treatments for gout, with a substantial market potential due to the increasing prevalence of hyperuricemia and gout [7] Summary by Sections 1. Pharmaceutical Market Tracking - The pharmaceutical industry outperformed the CSI 300 index by 2.91 percentage points in the past week, with a weekly increase of 4.00%, ranking second among 31 primary industry indices [19] - Over the past month, the pharmaceutical sector outperformed the CSI 300 index by 5.90 percentage points, with an increase of 11.51%, ranking fourth among primary industry indices [21] 2. Pharmaceutical Sector Trends and Valuation - The pharmaceutical sector has shown a 14.50% increase over the past six months, outperforming the CSI 300 index by 4.46 percentage points [36] - The current PE (TTM) for the pharmaceutical sector is 37.25, which is above the five-year historical average of 32.24 [39] 3. Recent Research Achievements - The research team has published several in-depth reports highlighting the positive trends in supply and demand within the pharmaceutical industry, including the growth of blood products and the acceleration of the import substitution process in inhalation preparations [44] 4. Recent Industry Policies and News - Recent measures from the National Medical Insurance Administration aim to support the high-quality development of innovative drugs, enhancing their market access and clinical application [46] - Notable industry news includes the approval of new indications for existing drugs and significant collaborations between major pharmaceutical companies [47][49]

截至2025年6月30日，中金公司旗下中金安心回报灵活配置混合C（920921）期末净资产0.67亿元，比上 期减少0.68%，该基金经理为顾柔刚。 简历显示，顾柔刚先生:国籍中国,管理学硕士。曾任中国农业银行信用卡中心市场部经理,瑞银集团研究 部研究助理,申万宏源证券研究所海外消费分析师,光大证券研究所海外消费首席分析师;2018年6月加盟 鹏华基金管理有限公司,现任国际业务部基金经理。2019年04月20日至2021年6月22日担任鹏华港美互联 股票(LOF)基金基金经理。顾柔刚先生具备基金从业资格。2021年6月22日起不在担任鹏华红利优选混 合型证券投资基金基金经理。现任中金安心回报灵活配置混合型集合资产管理计划基金经理。 本文源自：金融界 作者：基金君 日期期间申购（亿份）期间赎回（亿份）期末总份额（亿份）期末净资产（亿元）净资产变动率2025- 06-300.000.010.020.02-24.80%2025-03-310.000.000.020.02-2.54%2024-12-310.000.020.020.02-47.96%2024- 09-300.000.020.040.04-27.77% ...

Group 1 - The offline channels in the pharmaceutical and health industry have undergone significant changes due to industry policies, demographic shifts, and changing consumer habits, with traditional chain pharmacies reducing store numbers and transitioning to diversified operations [1] - Chinese medicine production companies are increasingly focusing on the health sector, with a notable rise in the importance of health products, as market entry barriers for these products are lower compared to pharmaceuticals [1] - Chain pharmacies are adopting a mixed business model, integrating health food sales alongside traditional products, which is seen as a growth opportunity [1] Group 2 - Yabao Pharmaceutical plans to invest over 100 million yuan to establish 500 Yabao Life Halls, targeting the elderly demographic and combining physical stores with online promotions [2] - Yabao Life Halls have rapidly expanded, with over 3,000 locations currently and plans to reach 5,000 by the end of the year, with low initial investment costs for franchisees [2] - Guangyuyuan has launched a plan to expand its store count from approximately 500 to 1,000, focusing on health products like medicinal wine and herbal teas [4] Group 3 - Chain pharmacies are experiencing a contraction phase, with major players like Dazhenlin and Laobaixing closing over 1,000 stores due to poor performance [6] - The number of retail pharmacies is projected to decline significantly, with an expected closure of 14,114 stores in 2024, indicating a turning point in the industry [6] - Many pharmacies are reducing their operational space and shifting focus to health food products, reflecting a strategic pivot in response to changing consumer purchasing behaviors [7][9] Group 4 - The sale of health food products in pharmacies is still in the exploratory phase, with staff often lacking knowledge about these products, which hinders sales [10] - Several chain pharmacies view health food products as a key area for future transformation, with some adjusting their business scope to include food sales [12][13]

Summary of Conference Call Notes Industry or Company Involved - The discussion primarily revolves around the pharmaceutical industry, particularly focusing on the implications of U.S. drug pricing policies and U.S.-China trade negotiations on Chinese pharmaceutical companies and their market opportunities. Core Points and Arguments 1. **Positive Impact of U.S.-China Negotiations on Pharmaceuticals** The recent U.S.-China negotiations are viewed as a significant positive for the pharmaceutical sector, alleviating previous concerns regarding trade impacts on drug pricing and exports of innovative drugs and raw materials [1] 2. **U.S. Drug Pricing Policy Changes** Trump's announcement of an executive order to reduce prescription drug prices by 30% to 80% is highlighted. The U.S. drug pricing system, characterized by high list prices, is under scrutiny, with the potential for significant price reductions impacting the market [2][3] 3. **Global Drug Pricing Context** U.S. drug prices are noted to be among the highest globally, particularly for innovative drugs, which are approximately 300% higher than prices in countries like Japan and Germany. This pricing structure encourages innovation but also raises concerns about affordability [3] 4. **Encouragement of Competition** The U.S. policy aims to accelerate competition among high-priced drugs, encouraging the entry of biosimilars and generic drugs, which could benefit Chinese pharmaceutical companies that can offer lower-cost alternatives [4][6] 5. **Opportunities for Chinese Pharmaceutical Companies** The reduction in U.S. drug prices is expected to create opportunities for Chinese companies, particularly in the fast-follow and biosimilar segments, as they can provide high-quality, cost-effective alternatives [6][8] 6. **Long-term Trends Favoring Chinese Innovation** The inefficiencies in innovation among multinational pharmaceutical companies may lead to increased reliance on Chinese innovation and manufacturing capabilities, especially if U.S. companies face cost pressures [7][8] 7. **Market Dynamics and Export Opportunities** The easing of trade tensions is anticipated to enhance the macroeconomic environment in China, leading to improved domestic demand and potential export opportunities for medical devices and raw materials [10][9] 8. **Impact of Drug Price Reductions on Market Dynamics** The anticipated drug price reductions in the U.S. are not expected to significantly diminish the addressable market for Chinese companies, as their market share in the U.S. remains relatively small [11][12] 9. **Long-term Supply Chain Considerations** U.S. concerns regarding supply chain security may lead to a push for domestic manufacturing, which could have long-term implications for Chinese companies seeking to penetrate the U.S. market [14][15] 10. **Investment Recommendations** The call suggests focusing on three categories of companies: innovative leaders, those with strong business development (BD) expectations, and upstream suppliers with global advantages, as the market enters a new growth cycle [16][18] Other Important but Possibly Overlooked Content 1. **Sector-Specific Insights** The discussion includes insights into specific companies and their competitive advantages, such as the potential for certain drugs to achieve significant market penetration despite pricing pressures [31][33] 2. **Emerging Trends in Medical Devices** The call also touches on the medical device sector, emphasizing the importance of high-end equipment and the potential for growth in home healthcare products, which may offer higher profit margins compared to domestic markets [25][26] 3. **Long-term Growth Projections** There is an optimistic outlook for the pharmaceutical sector, with expectations of a gradual recovery in demand and performance improvements in the coming years, driven by policy support and market dynamics [29][40] 4. **Focus on Innovation and R&D** The emphasis on innovation and the need for companies to adapt to changing market conditions is reiterated, highlighting the importance of R&D in maintaining competitive advantages [19][20] 5. **Market Sentiment and Future Outlook** The overall sentiment is cautiously optimistic, with a belief that the current market conditions present opportunities for growth and investment in the pharmaceutical and medical device sectors [46][47]

Market Overview - The Shanghai Composite Index is at 3500.42 points, slightly down by 0.13%, with a total trading volume of 674.96 billion yuan [1] - As of now, 50 A-shares have surpassed their annual line, indicating a positive market sentiment [1] Notable Stocks - The stocks with the highest deviation rates above the annual line include: - Furui Co., Ltd. (300049) with a deviation rate of 5.83% and a daily increase of 7.83% [1] - Haide Co., Ltd. (000567) with a deviation rate of 4.84% and a daily increase of 7.77% [1] - Tianye Co., Ltd. (832023) with a deviation rate of 3.71% and a daily increase of 6.35% [1] - Other stocks that have just crossed the annual line with smaller deviation rates include: - Wansheng Co., Ltd. (002739) with a deviation rate of 2.70% and a daily increase of 3.02% [1] - ST Guandian (688287) with a deviation rate of 2.14% and a daily increase of 2.67% [1] Trading Activity - The trading turnover rate for notable stocks varies, with Furui Co., Ltd. at 4.06% and Haide Co., Ltd. at 2.59% [1] - The latest prices for these stocks are as follows: - Furui Co., Ltd. at 39.40 yuan [1] - Haide Co., Ltd. at 6.52 yuan [1] - Tianye Co., Ltd. at 4.69 yuan [1]

Core Viewpoint - Fund manager Chen Qiming has managed two funds as of the end of Q2 2025, with the best-performing fund being Huafu Tianxin Flexible Allocation Mixed A (003152), which achieved a net value increase of 0.92% in the quarter [1]. Fund Performance Summary - Chen Qiming's managed funds include: - Huafu Dacai Flexible Allocation Mixed C (003153) with an annualized return of 5.68% and a Q2 increase of 0.70%, holding a major stock, Xuguang Electronics (600353.SH), at 7.23% of net value [2]. - Huafu Daxin Flexible Allocation Mixed A (003152) with an annualized return of 6.53% and a Q2 increase of 0.92%, also holding Xuguang Electronics at 7.23% of net value [2]. - During his tenure managing Huafu Value Growth Mixed A (410007), Chen achieved a cumulative return of 232.74% with an average annualized return of 11.77%, executing 96 stock adjustments with a success rate of 63.54% [2]. Stock Adjustment Cases - Notable stock adjustment cases managed by Chen Qiming include: - Boteng Co., Ltd. (300363) was bought in Q2 2018 and sold in Q3 2022, yielding an estimated return of 396.40% with a company performance growth of 1510.87% during the holding period [5]. - Yifeng Pharmacy (603939) was bought in Q2 2016 and sold in Q2 2019, yielding an estimated return of 96.12% with a company performance growth of 175.23% during the holding period [6]. - Beilu Pharmaceutical (300016) was bought in Q2 2015 and sold in Q1 2017, resulting in a loss of -59.25% despite a company performance growth of 264.70% during the holding period [7].

Group 1: Medical Devices - The medical device sector is expected to see a recovery in performance in H2 2025, driven by the resumption of hospital tenders and inventory clearance [5][34]. - High-value consumables are anticipated to benefit from significant domestic substitution opportunities and the completion of centralized procurement, leading to improved performance elasticity for companies [5][24]. - The home medical sector is projected to recover growth due to an improved consumer environment and ongoing new product investments [5][35]. - The IVD (in vitro diagnostics) sector is expected to enter a structural recovery phase, with head companies and differentiated competitors seeking innovation and overseas expansion [5][28]. Group 2: Investment Recommendations - Recommended companies in the medical device sector include Xinhua Medical, Kaili Medical, Mindray Medical, and Union Medical, with a focus on those benefiting from tender recovery and overseas expansion [5][36]. - For high-value consumables, companies like Microelectrophysiology and Microinvasive Medical are highlighted, particularly those in electrophysiology, orthopedics, and coronary intervention [5][36]. - IVD companies with high technical barriers and continuous new product launches, such as Aide Biological, are also recommended [5][36]. Group 3: Chain Pharmacies - The chain pharmacy sector is experiencing a recovery in performance expectations and valuation due to diversified product expansion [41]. - The industry is witnessing an acceleration in store closures and a slowdown in new openings, with leading companies expected to increase their market share [42][60]. - Recommended leading pharmacy companies include Dazhenlin, Yifeng Pharmacy, and Laobaixing, with a focus on those with superior management capabilities [43][87]. Group 4: Valuation and Market Dynamics - The valuation of chain pharmacies has seen recovery due to improved profit growth expectations and diversified strategies [47]. - The supply side is facing stricter drug price controls, but leading pharmacies are expected to maintain better pricing power due to their market position [56]. - The industry is undergoing adjustments, with leading companies likely to recover profit growth in 2025 as they adapt to market changes [74][79].