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Cell子刊:浙江大学周民团队开发药食同源策略,增强抗肿瘤免疫的同时降低毒副作用
生物世界· 2025-08-25 08:10
撰文丨王聪 编辑丨王多鱼 排版丨水成文 免疫检查点阻断 (ICB) 疗法通过唤醒人体自身的免疫系统来对抗肿瘤,从而彻底改变了癌症的治疗方式。然而,许多癌症患者仍对这种疗法无响应,且有相当 一部分患者会遭受严重的副作用,尤其是肠道和肺部的损伤。最近的研究表明,我们体内数以万亿计的微生物组成的肠道微生物群,在 ICB 疗法的有效性和安全 性方面发挥着至关重要的作用。 2025 年 8 月 22 日,浙江大学 周民 教授团队在 Cell 子刊 Cell Biomaterials 上发表了题为: Enhancing anti-tumor immunity and reducing toxicity: A medicine and food homology formula for ICB therapy 的研究论文。 该研究开发了一种 药食同源 配方——使用 微球 ( MS ) 共载 普通小球藻 ( C. vulgaris ) 和 黄芪多糖 (APS ) —— CV /APS-MS ,有助于在 改善免疫检 查点阻断疗法的癌症免疫治疗效果的同时,减少 免疫相关不良事件 (irAE) 风险,为更安全、更有效的免疫检查点阻 ...
福瑞达:2025年上半年颐莲品牌收入5.54亿元,同比增长23.78%
Core Insights - The company reported a revenue of 1.79 billion yuan in the first half of 2025, with a net profit of 108 million yuan, and total assets of 6.037 billion yuan as of June 30, 2025 [1][2] Group 1: Cosmetics Business - The cosmetics segment generated a revenue of 1.094 billion yuan in the first half of 2025, with the Yilian brand achieving 554 million yuan, reflecting a year-on-year growth of 23.78% [2] - The Yilian brand launched a global spokesperson, Zhang Linghe, and held a summer spray festival, with spray product line sales reaching 482 million yuan, an increase of 43% [2] - The Aier Doctor brand reported a revenue of 451 million yuan, with new products like the 287 mask and 287 lotion, generating nearly 10 million yuan in sales within two months of launch [2] Group 2: Pharmaceutical Business - The pharmaceutical segment achieved a revenue of 207 million yuan, expanding its client base by over 200 hospitals and OTC customers [2] - Key products include children's flu medication and a popular pain relief product recognized at the Wuzhen Health Conference [2] - The company is actively developing food-medicine integration standards and collaborating with major clients to enhance raw material supply [2] Group 3: Raw Materials and Additives - The raw materials and additives segment reported a revenue of 179 million yuan, with hyaluronic acid sales reaching 116 million yuan, a year-on-year increase of 23.4% [3] - Medical-grade hyaluronic acid sales surged by 287.3%, totaling 16.08 million yuan [3] - The overall gross margin for the hyaluronic acid business improved to 47.1%, up by 8.5 percentage points [3] Group 4: Innovation and R&D - The company launched over 80 new products in the cosmetics sector, including the Aier Doctor 287 mask and Yilian purple essence water [3] - The company introduced a pioneering transdermal collagen technology, enhancing skin penetration by 27.5 times [3] - The company has made significant progress in medical device registrations and drug development, including obtaining production licenses for various products [3]
守正创新 擦亮“中华老字号”金字招牌 粤万年青积极打造大健康集团
在广东汕头,一家拥有130余年历史的中药企业正焕发新生。 广东万年青(000789)制药股份有限公司(粤万年青(301111))董事长、总裁欧先涛在接受中国证券 报记者采访时介绍,近年来,公司收购了上游饮片企业,进入健康食品领域,打造提供一站式健康管理 的万年青国际医疗港,不断完善全产业链布局,从传统药企升级为覆盖"医药+健康食品+医疗"的综合 性大健康集团。粤万年青正以"中华老字号"的深厚积淀为基,以科技创新为翼,在传承与创新中书写中 医药现代化的新篇章。 传承非遗技艺 2024年,"万年青"被商务部认定为"中华老字号",这一认证标志着粤万年青跨越三个多世纪的技艺传承 与品质坚守获得认可,成为企业在中医药市场中的金字招牌。 欧先涛介绍,粤万年青目前拥有101个药品批文,32个原研首创产品,10个独家品种,4个独家剂型,16 个国家基药目录产品,38个产品列入国家医保目录。重点产品包括参芪降糖片、益心丸、消炎利胆片 等。万年青固精补肾丸制作技艺被认定为汕头市第八批市级非物质文化遗产代表性项目,公司也被认定 为非物质文化遗产代表性项目保护单位。 粤万年青也致力于实现中药生产的现代化和智能化。公司通过技术创新实现 ...
仲景食品上市后首现半年营收下滑
Bei Jing Shang Bao· 2025-08-19 16:16
Core Viewpoint - Zhongjing Foods reported a "revenue growth without profit growth" for the first half of the year, marking the first decline in half-year revenue since its listing in 2020 [1] Financial Performance - Revenue for the first half of the year was 524 million yuan, a year-on-year decrease of 2.5% [1] - Net profit attributable to shareholders was 101 million yuan, a slight increase of 0.29% year-on-year [1] - The seasoning food and seasoning ingredient segments both experienced revenue declines, with the seasoning food segment generating 310 million yuan (down 2.31%) and the seasoning ingredient segment generating 212 million yuan (down 1.31%) [1] Product Performance and Market Challenges - The Shanghai scallion oil, launched in 2021 as a "second growth engine," saw sales reach 89.39 million yuan in the first nine months of 2023, a year-on-year increase of 113.24% [2] - Despite its initial success, the product faced challenges from counterfeit products and increased competition, leading to a decline in revenue [2] - The brand's positioning is seen as too regional, limiting its appeal beyond local markets, and it struggles to capture the younger demographic and health-conscious consumers [2] Innovation and Market Expansion - Zhongjing Foods has been focusing on product innovation, launching new products such as garlic sauce and ginger-garlic sauce, which have performed well in sales rankings [3] - The company is also targeting the B2B market with new restaurant-specific seasonings and has established partnerships with several chain restaurants [3] - Despite these efforts, new product launches have not yet significantly boosted overall revenue [3] Future Prospects - The company is exploring the health food sector, with plans for a new instant health product, "Zhongjing Vitality Ginseng," currently in the research and development phase [3] - There are challenges in consumer perception and regulatory compliance for health food products, which may delay their contribution to revenue [3]
苏州稻香村月饼生产进入中秋旺季
Bei Ke Cai Jing· 2025-08-10 02:19
Group 1 - The core viewpoint of the articles highlights that Suzhou Daoxiangcun Group has officially entered the peak production season for mooncakes with the commencement of its 2025 Mid-Autumn Festival mooncake production [1] - Suzhou Daoxiangcun has maintained an annual mooncake production of over 300 million pieces in recent years and has adopted a sales-driven production model [1] - The company anticipates better sales performance for its mooncakes this year based on order and prepayment data from recent marketing and ordering meetings [1] Group 2 - Suzhou Daoxiangcun, founded in 1773, is recognized as a time-honored brand by the Ministry of Commerce and has established 10 industrial parks across various provinces and cities in China [2] - Over the past decade, Suzhou Daoxiangcun has produced and sold nearly 2 billion mooncakes and exported over 100 million mooncakes to more than 60 countries and regions, covering nearly 90% of developed markets [2] - The company is focusing on comprehensive quality upgrades for its mooncakes, including improvements in ingredient formulation, taste, health aspects, and innovative packaging that incorporates traditional cultural elements [1]
“中医药+餐饮” 养生消费新潮流
Sou Hu Cai Jing· 2025-08-04 23:41
顾客走进北京同仁堂大栅栏店。 在同仁堂知嘛健康北京正大店内拍摄的中草药草本饮品。 广西鹿寨县拉沟乡举办第三届药王节,通过药膳美食展示等形式多样的活动,吸引游客前来体验游玩。 在广西鹿寨县拉沟乡木龙村五家屯,游客了解药膳美食的制作环节。 本版照片均为新华社发 养生茶饮、药膳糕点、中药面包……如今,越来越多的中医药养生产品走出药房,走向市场。 餐饮和传统中医药的融合越来越深入,许多老字号中药店、中医院推出了中药茶饮和食品。北京白塔寺 药店顺应节气将枇杷和梨汁融入咖啡之中,推出枇梨杷啦拿铁;天津中医药大学第一附属医院推出黄芪 养生包等中药面包;一些餐厅根据顾客不同体质和需求,制作当归羊肉汤、枸杞炖鸡等药膳…… "'中医药+餐饮'的创新融合掀起了新潮流,中药面包、中药冰淇淋、中药咖啡等产品吸引了很多消费 者,体现了当前人们的健康意识不断增强。这股潮流也带动了更多人了解中医药知识和养生理念。"中 国中医科学院西苑医院治未病中心主任张晋说。 在甘肃省定西市中医医院,工作人员在配制中药茶饮。 "过去我们认为药膳的消费群体以中老年为主,但通过调研发现,目前消费者群体具有年轻化特征,95 后到00后的年轻人消费增速明显。"国家 ...
四川:内江天冬全产业链发展助力乡村振兴
Xin Hua Cai Jing· 2025-08-01 14:05
Core Insights - The introduction of "Tian Dong" (Asparagus cochinchinensis) into the "food and medicinal" category by the National Health Commission and the State Administration for Market Regulation has created new development opportunities for the industry [1][3] - The market demand for Tian Dong products, including Tian Dong powder, beverages, and personal care items, has significantly increased, leading to higher prices and greater planting enthusiasm among farmers [1][2] Industry Overview - The Tian Dong planting area in Dongxing District has reached nearly 50,000 acres, with a comprehensive industrial output value exceeding 1.03 billion yuan [5] - The average profit per acre of Tian Dong is approximately 30,000 yuan, with fresh Tian Dong selling for about 3.5 yuan per pound [2][1] - The establishment of 54 ecological planting bases aims to ensure the quality of Tian Dong, supported by collaborations with various research institutions [2][3] Product Development - Over 40 health products derived from Tian Dong have been developed, including Tian Dong paste, powder, and beverages, generating sales of over 30 million yuan [3] - The company Sichuan Tiancao Rundong Biotechnology Co., Ltd. aims to achieve a production value of 50 million yuan for Tian Dong-related products this year [3] Strategic Initiatives - Dongxing District is implementing a "seven-in-one" strategy for the entire industrial chain, focusing on seedling cultivation, planting, processing, trading, product research and development, brand marketing, and health tourism [5] - The district is leveraging policy support and technological innovation to enhance the Tian Dong industry and contribute to rural revitalization [5]
花开橄榄 珠乡四溢—— 浦北珠乡倾情上演“健康+非遗”月饼盛宴
Zhong Guo Shi Pin Wang· 2025-07-28 03:35
Core Viewpoint - The "Flowering Olive: Zhu Township's Flourishing" event showcased the modern inheritance and industrial upgrade of intangible cultural heritage through the promotion of Zhu Township's olive mooncakes, enhancing the cultural value and market opportunities ahead of the Mid-Autumn Festival and National Day celebrations [1][3][6]. Group 1: Event Highlights - The event featured immersive experiences, including a live demonstration of traditional mooncake making, emphasizing the unique flavors and cultural significance of Zhu Township's olive mooncakes [3]. - The participation of government representatives, industry experts, and media guests highlighted the collaborative spirit and potential for business partnerships within the food industry [1][3]. Group 2: Company Developments - Zhu Township Olive Food Co., Ltd. has established three main product lines: olive mooncakes, selenium-rich olive vinegar, and olive sauce pickles, focusing on health-oriented products without artificial additives [6][8]. - The company aims to expand its market presence beyond Guangxi, targeting major cities like Beijing, Shanghai, and Guangzhou, and has secured a green channel for inspection-free sales in Hong Kong [6][8]. Group 3: Industry Strategy - The company emphasizes a "health, innovation, and sharing" development philosophy, leveraging the advantages of the health industry park to enhance collaboration with various enterprises and promote the olive industry towards high-end and international markets [8]. - The establishment of the Zhu Township Food Health Industry Park is positioned as a key driver for the local food industry, integrating various functions to support the modernization and scaling of food enterprises [8].
新茶饮飘出西北味
Jing Ji Ri Bao· 2025-07-26 22:27
Core Insights - The article highlights the rise of "sweet chaozi milk tea" in Lanzhou, which combines local flavors with modern beverage trends, becoming a popular choice among consumers and a symbol of regional cultural identity [1][5][9] Group 1: Product Innovation - The "Fang Ha" tea brand successfully transformed traditional local ingredients like sweet chaozi and fermented vegetable water into modern drinks, achieving annual sales of over 5.3 million cups for sweet chaozi milk tea [5][11] - The development process involved overcoming initial skepticism and taste challenges, ultimately leading to a balanced flavor profile that resonates with local consumers [3][4] - New product innovations, such as "lemon mint fermented water" and "lemon cucumber fermented water," have been introduced to cater to younger consumers' preferences [4][11] Group 2: Market Expansion - "Fang Ha" has expanded to 133 stores across Gansu, Shaanxi, Qinghai, and Ningxia, indicating a growing market presence and demand for local flavors [5][10] - The brand's strategy includes integrating local cultural elements into its marketing, such as collaborating with local events like marathons to enhance brand visibility [9][10] Group 3: Cultural Integration - The tea brands emphasize the importance of cultural storytelling, positioning their products as not just beverages but as experiences that reflect the rich heritage of the Northwest region [9][10] - The "Ciyuan Tea House" initiative aims to modernize traditional Chinese medicine concepts, appealing to younger demographics while maintaining cultural authenticity [7][11] Group 4: Challenges and Future Outlook - The industry faces challenges in consumer acceptance of unique local flavors, as many consumers are accustomed to sweeter, more artificial tastes [11][12] - There is a need for continuous innovation and education to bridge the gap between traditional flavors and modern consumer preferences, ensuring sustainable growth in the market [10][11]
碧生源蓝帽子袋泡茶:传统茶产业工业化升级的探索
Jing Ji Wang· 2025-07-24 08:17
Core Insights - The company Biyuan has gained popularity in the functional tea market with its "Blue Hat" certified products, Changrun Tea and Changjing Tea, which effectively combine tea with traditional Chinese herbal medicine [1][2] - Biyuan aims to modernize the traditional Chinese tea industry by utilizing industrialized methods to standardize traditional tea formulas, addressing the long-standing issue of "having categories but no brands" in the industry [1][2] - The company has initiated a partner operation mechanism in 2023 to streamline its organizational structure, ensuring efficient communication between frontline and headquarters, which has led to a significant recovery in performance [2] Company Strategy - Biyuan's brand name signifies "the source of green life," aligning with its focus on green, natural, and healthy products, while also aiming to establish long-term connections with consumers [1] - The company has implemented a flat organizational structure, allowing operational staff to become shareholders, linking their income directly to sales performance [2] - Biyuan has established a strict standardized system for product development and production, ensuring all raw materials comply with national health food regulations and maintaining real-time data connectivity with the Beijing Drug Administration [2] Cultural and Industrial Impact - Biyuan is advocating for the recognition of "Oriental Tea Art" as an intangible cultural heritage, positioning itself at the forefront of the tea industrialization movement [3] - The company combines traditional culture with innovative industrial practices through the use of bagged tea, effectively preserving and promoting Chinese heritage [3]