LEXINGTON, Mass., July 2, 2025 /PRNewswire/ -- Curis, Inc. ("Curis") (NASDAQ: CRIS), a biotechnology company focused on the development of emavusertib (CA-4948), an orally available, small molecule IRAK4 inhibitor, today announced that it has entered into a definitive agreement with a combination of existing and new investors for the purchase of 1,538,460 shares ("Shares") of its common stock in a registered direct offering priced at-the-market under Nasdaq rules. In a concurrent private placement, Curis al ...

Core Insights - Altria Group, Inc. is committed to transitioning towards a smoke-free future, with a focus on its oral tobacco portfolio, particularly the on! nicotine pouch brand, which has shown significant growth in shipment volumes and market share [1][2][9] - The company's oral tobacco revenues increased by 0.5% to $654 million in Q1 2025, driven by pricing power despite macroeconomic challenges [2] - Altria faces challenges in the vapor segment, particularly after regulatory issues led to the discontinuation of its NJOY ACE product, but plans to introduce compliant alternatives [3][4] Oral Tobacco Performance - The on! nicotine pouch brand's shipment volumes rose 18% year-over-year, exceeding 39 million cans, and its market share in the oral tobacco category increased by 1.8 percentage points to 8.8% [1][9] - The nicotine pouch market share for on! reached 17.9%, indicating strong consumer loyalty and brand strength despite retail price increases [1] Vapor Segment Challenges - Regulatory setbacks have impacted Altria's vapor products, leading to the discontinuation of NJOY ACE, but the company is working on launching new compliant products to regain market share [3][4] Competitive Landscape - Altria competes with Philip Morris International and British American Tobacco in the smoke-free category, both of which are also focusing on reduced-risk products [5][6][7] - Philip Morris reported a 20.4% increase in net revenues and a 33.1% rise in smoke-free gross profit, with significant growth in its ZYN and VEEV products [6] - British American Tobacco aims for 50 million consumers by 2030 and reported a 2.5% increase in New Category revenues in 2024 [7] Financial Performance and Valuation - Altria's stock has gained 12.5% year-to-date, while the industry has grown by 37.7% [8] - The company trades at a forward price-to-earnings ratio of 10.76X, below the industry average of 15.36X [11] - Earnings estimates for 2025 and 2026 suggest year-over-year growth of 4.9% and 3.3%, respectively, with recent upward revisions [12]

Core Viewpoint - The U.S. Supreme Court ruled that individuals adversely affected by FDA orders can challenge the agency in court, affirming the right of retailers to contest FDA decisions that impact their sales [1][2][3]. Group 1: Legal Context - Under the Family Smoking Prevention and Tobacco Control Act (TCA), manufacturers must obtain FDA approval to sell certain vaping products, such as R.J. Reynolds' "Vuse" e-cigarettes [2]. - The FDA denied R.J. Reynolds' application, which led to a ban on the sale of Vuse e-cigarettes by retailers who were previously allowed to sell them while the application was pending [2]. - Retailers argued that the FDA's decision adversely affected them by resulting in lost sales, leading to a petition for review in the U.S. Court of Appeals for the Fifth Circuit [2]. Group 2: Court Rulings - The Fifth Circuit ruled that retailers have standing to challenge the FDA's decision, rejecting the FDA's argument that only the manufacturer could be considered "adversely affected" under the TCA [2]. - The Supreme Court affirmed the Fifth Circuit's judgment, reinforcing the broad interpretation of "adversely affected" as it relates to judicial review of agency actions [3]. Group 3: Implications of the Ruling - The ruling prevents the FDA from narrowing the scope of judicial review provisions under the TCA and other statutes, allowing those harmed by agency actions to seek relief in federal court [3]. - The decision is seen as a significant affirmation of the ability for individuals and entities to challenge federal regulations, even if they were not directly involved in the agency's decision-making process [4].

Key Takeaways Altria sees over 60% of the U.S. e-vapor market controlled by unauthorized disposable products. MO's smoke-free growth faces pressure from illicit competition and softening cigarette volumes. MO trades at 10.96X forward P/E vs. 15.74X industry average, with 5.3% 2025 EPS growth forecast.Altria Group, Inc. (MO) is facing growing challenges as it shifts its focus toward smoke-free alternatives. The company's efforts are being threatened by the rapid rise of illicit flavored disposable e-vapor ...

Key Takeaways PM's smoke-free products made up 44% of Q1 gross profit, led by IQOS and ZYN shipments. ZYN shipments soared 53% in Q1, with PM raising 2025 shipment guidance to 800-840 million cans. PM's smoke-free gross margin topped 70%, far exceeding combustibles, with products in 95 markets.Philip Morris International Inc. (PM) is accelerating its shift from traditional tobacco to reduced-risk products, with strong momentum in its flagship offerings — IQOS and ZYN. In the first quarter of 2025, smoke-f ...

证券研究报告·行业点评报告 2025 年 6 月 11 日 江海证券研究发展部 消费行业研究组 分析师：张婧 执业证书编号：S1410525010001 行业评级：增持（维持） 近十二个月行业表现 % 1 个月 3 个月 12 个月 相对收益 4.33 4.58 5.82 绝对收益 4.83 2.59 13.97 数据来源：聚源 注：相对收益与沪深 300 相比 注：2025 年 6 月 10 日数据 -27% -16% -5% 6% 18% 29% 2024-06 2024-10 2025-02 2025-06 轻工制造 沪深300 相关研究报告 1. 江海证券-行业点评报告-轻工制造：中 美日内瓦联合声明发布，出口链有望得到 修复 – 2025.05.16 2. 江海证券-行业点评报告-轻工行业： 2025 年智能眼镜进入新品密集发布期 – 2025.02.22 英美烟草发布 2025H1 业绩前瞻，关注 新品 Glo Hilo 日本表现 事件： 投资要点： ◆投资建议：关注 6 月份日本仙台市场及后续日本全国上市之后的销售表现，HNB 产业链将会迎来机会。 HNB 由于替烟减害效果出色，在全球渗透率提升 ...

本周研究跟踪与投资思考：英美烟草更新 2025 上半年交易，收入略超指引， Glo Hilo 6 月 9 日正式进入日本市场，关注日本消费者产品反馈；布鲁可 6 月 9 日调入港股通，建议继续关注全人群、全价位与全球化策略推进节奏。 英美烟草 2025H1 收入略超指引目标，Glo Hilo 于 6 月 9 日在日本上市。1） 英美烟草 BAT 更新 2025 上半年交易，H1 收入略超此前指引，H2 有望加速增 长。新型烟草方面，上半年电子烟 Vuse 收入预计下降 15%左右，主要系受美 国和加拿大非法电子烟市场影响；口含烟 Velo 实现双位数增长，其中美国 市场预计三位数增长；加热不燃烧Glo预计低个位数增长，塞尔维亚Glo Hilo 表现较好，试用转化率翻番，下半年将继续在主要市场分阶段推广，公司预 计有望加速增长。2）Glo Hilo 正式进入日本市场：根据 BAT 日本公司，6 月 9 日 Glo Hilo 与其专属烟弹 Virto 将在仙台主要便利店及 Glo 官网面向 居住在宫城县的消费者正式发售，自 6 月 14 日起 Hilo 也将在仙台快闪店售 出。日本是全球最成熟的 HNB 消费市场 ...

行业报告 | 行业研究周报 新兴产业 证券研究报告 英美烟草下半年聚焦 Glo 新品市场扩张；25 年 4 月中国电子烟出口额保持平稳！ 本周关注：英美烟草下半年聚焦 Glo 新品市场扩张；25 年 4 月中国电子烟出口额保持平稳 英美烟草发布业绩预告：预计 25 财年营收表现好于预期，期待下半年创新产品驱动业绩增长 2025 年 6 月 3 日，英美烟草发布《2025 年上半年收盘前交易更新》公告，公告显示其 25 年上半 年营收好于同期，25 财年营收预计将增长 1-2%，调整后营收利润将增加 1.5%-2.5%，业绩整 体符合预期且韧性较强。 受可燃烟草产品交付能力增强及现代口含烟 Velo Plus 推动，美国市场上半年及全年有望恢复收入 和利润增长。尽管行业销量同比下降约 9%，但英美烟草在美国的价值份额和销量份额均实现巩 固。排除其未涉及的细分市场，凭借 Natural American Spirit 和 Lucky Strike 品牌的推动，英美 烟草正在占取市场份额。同时美洲、中东和欧洲地区（AME）持续表现强劲；亚太、中东和非洲地 区（APMEA）如先前指引所述受到孟加拉国和澳大利亚消费税及 ...

Investment Rating - The industry investment rating is "Hold" [1] Core Insights - British American Tobacco (BAT) forecasts a revenue growth of 1-2% for H1 2025, with adjusted operating profit expected to increase by 1.5%-2.5% [3][18] - The Glo Hilo product has shown positive market response, with a significant increase in conversion rates in Serbia and expected revenue acceleration in the second half of the year [3][19] - The heated tobacco market is projected to reach approximately $34.463 billion in 2023, with a year-on-year growth of 12.22% [3][23] Summary by Sections Weekly Topic - BAT's H1 2025 performance forecast indicates a slight decline in market share in key markets, but a recovery in the US market with a 10 basis point increase in sales volume and revenue share [3][18] - The Velo product line has seen a market share increase to 29.7%, with double-digit revenue growth, while the Glo Hilo's innovative launch is expected to boost performance in the latter half of the year [3][18] Weekly Market Review - From June 2 to June 6, 2025, the Shanghai Composite Index rose by 1.13%, with the light industry manufacturing sector increasing by 2.18%, ranking 8th among 31 sectors [4][28] - The textile and apparel sector saw a 1.89% increase, ranking 11th among the same sectors [4][28] Key Data Tracking Home Furnishing - In the week of May 25 to June 1, 2025, the transaction area of commercial housing in 30 major cities was 2.1262 million square meters, a 3.25% increase month-on-month [7][36] - The sales area of commercial housing for the first four months of 2025 was 28.3 million square meters, a year-on-year decrease of 2.8% [7][36] Packaging and Paper - As of June 6, 2025, the prices for various paper products showed slight fluctuations, with needle pulp priced at 5977.5 yuan/ton, a decrease of 0.43% [8][48] - The price of waste paper products remained stable, with waste yellow board paper priced at 1478 yuan/ton [8][48] Textile and Apparel - As of June 6, 2025, the cotton price index in China was 14561 yuan/ton, showing a slight decrease of 0.12% [10][10] - In April 2025, the retail sales of clothing and textiles reached 108.8 billion yuan, a year-on-year increase of 2.2% [10][10]

行业报告 | 行业研究周报 新兴产业 证券研究报告 英美烟草下半年聚焦 Glo 新品市场扩张；25 年 4 月中国电子烟出口额保持平稳！ 本周关注：英美烟草下半年聚焦 Glo 新品市场扩张；25 年 4 月中国电子烟出口额保持平稳 英美烟草发布业绩预告：预计 25 财年营收表现好于预期，期待下半年创新产品驱动业绩增长 2025 年 6 月 3 日，英美烟草发布《2025 年上半年收盘前交易更新》公告，公告显示其 25 年上半 年营收好于同期，25 财年营收预计将增长 1-2%，调整后营收利润将增加 1.5%-2.5%，业绩整 体符合预期且韧性较强。 受可燃烟草产品交付能力增强及现代口含烟 Velo Plus 推动，美国市场上半年及全年有望恢复收入 和利润增长。尽管行业销量同比下降约 9%，但英美烟草在美国的价值份额和销量份额均实现巩 固。排除其未涉及的细分市场，凭借 Natural American Spirit 和 Lucky Strike 品牌的推动，英美 烟草正在占取市场份额。同时美洲、中东和欧洲地区（AME）持续表现强劲；亚太、中东和非洲地 区（APMEA）如先前指引所述受到孟加拉国和澳大利亚消费税及 ...