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“基因魔剪”携手AI提升DNA编辑精度 为未来精准基因疗法发展奠定基础
Ke Ji Ri Bao· 2025-08-13 00:09
Core Insights - Scientists from Swiss Federal Institute of Technology Zurich, University of Zurich, and Ghent University have developed an innovative gene editing method that combines advanced "gene scissors" technology with artificial intelligence (AI), significantly enhancing the precision of DNA editing [1][2] - The new AI tool named "Pythia" allows scientists to predict the outcomes of gene editing with unprecedented accuracy, particularly in how cells will repair DNA breaks caused by techniques like CRISPR/Cas9 [1][2] Group 1 - The technology aims to ensure that "gene scissors" do not cause unintended genetic mutations while maintaining overall genomic stability, which is crucial for safe treatments [1] - Pythia has been validated in human cell culture systems, achieving efficient and precise gene editing and foreign gene integration [2] - The method has been tested in various biological models, including African clawed frogs and live mice, successfully editing DNA in non-dividing tissues such as the brain [2] Group 2 - Pythia utilizes identifiable and learnable repair patterns, indicating that DNA repair processes are not random but follow specific rules [2] - The technology can modify single bases, insert foreign genes, and label specific proteins, enabling direct observation of protein behavior in healthy and diseased tissues [2] - Its versatility allows application in various cell types, including non-dividing cells like neurons, providing new hope for targeting difficult-to-treat neurological diseases [2] Group 3 - The predictive capability of Pythia is likened to meteorologists using AI to forecast weather, emphasizing its importance for safe, reliable, and clinically applicable gene editing [2]
我国构建世界最大规模原子量子计算系统
Ke Ji Ri Bao· 2025-08-13 00:09
(文章来源:科技日报) 传统的重排方法受限于随阵列规模增长的时间复杂度、原子丢失、计算速度等,阵列规模停留在几百个 原子的水平,难以进一步扩展。为攻克该难题,研究团队创新性地研发AI技术,实时驱动高速空间光 调制器进行动态刷新,通过对光镊阵列位置和相位的精确控制,同时移动所有原子。 在该研究中,研究团队演示了二维和三维原子阵列的任意构型重排,实现了高达2024个原子的无缺陷阵 列,总耗时仅为60毫秒。随着原子阵列规模增大,该重排方法耗时保持不变,未来可以直接应用于数万 原子规模的无缺陷阵列重排。目前,该系统单比特门保真度达99.97%,双比特门保真度达99.5%,探测 保真度达99.92%,已追平以美国哈佛大学为代表的国际最高水平,为构建基于中性原子阵列的容错通 用量子计算机奠定了技术基础。 记者12日从中国科学技术大学获悉,该校潘建伟院士、陆朝阳教授等与上海量子科学研究中心/上海人 工智能实验室钟翰森研究员等团队合作,利用人工智能(AI)技术,实现了高度并行性以及与阵列规 模无关的常数时间消耗,在60毫秒内成功构建了2024个原子的无缺陷二维和三维原子阵列,刷新了中性 原子体系无缺陷原子阵列规模的世界纪录。 ...
中国社科院人工智能研究促进中心揭牌
Ke Ji Ri Bao· 2025-08-13 00:07
Group 1 - The establishment of the Artificial Intelligence Research Promotion Center by the Chinese Academy of Social Sciences aims to address fundamental questions regarding the direction of the intelligent revolution and to provide a "Chinese solution" for global AI governance reform [1] - The center will focus on the intersection of artificial intelligence and major theoretical and practical issues in philosophy and social sciences, striving to create a leading research platform that reflects national will and mission [1] - The development and governance of artificial intelligence are not only technological issues but also involve economic, social, cultural, legal, ethical, diplomatic, and international political aspects [1] Group 2 - Artificial intelligence has become a core force driving industrial transformation and enhancing national competitiveness, with large models rapidly becoming foundational technologies across various application fields [2] - The introduction of large language models into social science research methods is reshaping traditional research approaches, enabling automation and efficiency in text analysis, data generation, and simulation experiments [2] - The emergence of code large models significantly lowers programming barriers, facilitating more efficient data processing and analysis for researchers, thus promoting innovation and development in social science research [2]
电化学海水提铀关键技术攻克
Ke Ji Ri Bao· 2025-08-13 00:05
记者12日从西南科技大学获悉,该校核素分离与核环境安全团队开发出一种协同配位—还原界面一体化 电极新材料,其能够从海水中电化学提取黑色二氧化铀产物,为全球铀资源开发提供了新思路。相关研 究成果近日发表于国际期刊《自然·通讯》。 在全球对清洁能源需求与日俱增的当下,核能作为高效、低碳能源的重要性愈发凸显。然而长期以来, 陆地铀资源的稀缺阻碍着核能产业稳健前行。电化学海水提铀技术被视为弥补铀资源空缺的可行方案。 目前,电化学海水提铀一直受到杂质共沉积的影响,这一问题始终制约其工业化进程。 针对海洋环境的复杂多变,研究团队提出将铀酰捕捉位点与还原位点在空间上进行统一,从而构筑协同 配位—还原位点,保证了四价铀的原位形成和保存,防止了碱在晶体转化过程中的共沉积。实验结果显 示,该电极新材料在实际海水中表现出每克每天产生2.65毫克铀的电化学铀提取能力,处于目前同类型 电极的国际最高水平。 此外,该团队还搭建了国际首台能源自持式流动型电化学海水提铀装置,将广袤海上的太阳能直接转化 为电能,实现无外加电场下的电化学海水提铀。在自然光日照条件下,该装置能够稳定输出3—5伏电 压。在海南棋子湾海域的中核集团海南海试平台,该装 ...
伪科普坑农 网络平台难辞其咎
Ke Ji Ri Bao· 2025-08-13 00:03
因此,打击伪农业科普,平台须扛起主体责任。专家的资质审核要严格,必要的学历核验、身份核查等 不可或缺。在内容审核方面,各平台也要提高专业化水平,对伪科普真带货、夸大农资农药功效等有害 视频和直播要加强监测和治理。同时,要畅通投诉举报渠道,发现问题及时作出禁言、封号等处理。 互联网监管部门也应"利剑出鞘",既加强对涉农信息的日常监管,也针对涉农科普领域的突出问题强化 专项治理。对那些屡出问题、影响恶劣的平台,该约谈的约谈,该处罚的处罚,以"强监管"督促平台落 实主体责任。 "味精加啤酒,增产又增收""量子赋能农作物,抗病抗灾还增产"……近日,媒体调查发现,一些荒诞的 伪农业科普在短视频平台肆意传播,不法分子借伪科普打造虚假人设,带货假冒伪劣农资产品,以"助 农"之名行"坑农"之实。 这些伪专家深谙流量密码:白大褂、农药架与"免费指导"的话术,营造权威的"专家形象";"花生膨大 粒粒饱"之类的噱头产品,精准戳中农民追求丰产的心理;啤酒灌根、食盐除草等似是而非的"小妙 招",把不明就里的农民轻松拿捏。 农业生产专业性强,需要真专家的科学指导,而伪科普的泛滥,混淆了农民的认知,可能让他们耽误农 时、蒙受损失。这种伤害 ...
正式发布!我国主导制定→
Ke Ji Ri Bao· 2025-08-12 10:29
Core Points - The China Aerospace Science and Technology Corporation has led the development of two international standards recently published by the International Organization for Standardization (ISO) [1] - A total of 30 international standards in the aerospace field have been published under China's leadership, with a cumulative total of 38 standards either published or in development [1] Group 1 - The first standard, "Aerospace Systems - Launch Window Estimation and Collision Avoidance" (ISO 21740:2025), outlines requirements for launch window analysis and safety launch timing identification, as well as a collision avoidance risk assessment matrix [1] - This standard is applicable to collision risk analysis between newly launched objects and any space objects along the flight path, facilitating the determination of optimal launch windows and timing [1] - The standard was jointly proposed by China, the United States, France, and Japan, with the China Aerospace Standardization Research Institute responsible for the drafting [1] Group 2 - The second standard, "Aerospace Systems - Requirements for Stable Operation of Satellite Attitude and Orbit Control Systems" (ISO 16615:2025), defines the stable operation of satellite attitude and orbit control systems in orbit [2] - It establishes principles and requirements for constructing the stable operation capability of satellite attitude and orbit control systems based on influencing factors [2]
中温固体氧化物燃料电池研制成功,有望大幅加快商业化进程
Ke Ji Ri Bao· 2025-08-12 07:23
Core Insights - Solid Oxide Fuel Cells (SOFC) are gaining attention due to their high efficiency and long lifespan, but their high operating temperatures (700-800 degrees Celsius) require expensive high-temperature materials, limiting widespread application [1] - A research team from Kyushu University in Japan has developed a new type of SOFC that can operate efficiently at a medium temperature of 300 degrees Celsius, potentially accelerating the commercialization of low-cost, low-temperature SOFCs [1] Group 1 - SOFCs utilize ceramics as electrolytes, and lowering the operating temperature can reduce manufacturing and maintenance costs [1] - Previous research attempted to enhance proton transport speed through chemical doping, but this often led to lattice blockage, slowing proton movement [1] - The new study aims to find oxide crystals that can accommodate a large number of protons while allowing them to move freely [1] Group 2 - The research team discovered that high concentrations of scandium doped into barium tin oxide and barium titanate can achieve a proton conductivity of over 0.01 S/cm at 300 degrees Celsius, comparable to the performance of traditional SOFC electrolytes at high temperatures [1] - Structural analysis and molecular dynamics simulations show that scandium atoms connect surrounding oxygen atoms into "ScO6 high-speed channels," allowing protons to pass through with very low migration barriers [2] - The findings address the long-standing challenge of balancing doping levels with ionic transport efficiency, providing a new pathway for developing low-cost, low-temperature SOFCs [2] Group 3 - The principle discovered is not only applicable to fuel cells but can also be extended to low-temperature electrolyzers, hydrogen pumps, and reactors that convert carbon dioxide into valuable chemicals, potentially having a broader impact on hydrogen energy adoption and carbon reduction [2]
最古老黑洞已有133亿岁“高龄”
Ke Ji Ri Bao· 2025-08-12 07:23
由美国得克萨斯大学奥斯汀分校科学家领衔的国际天文学家团队,利用詹姆斯·韦布空间望远镜,捕捉 到宇宙大爆炸后仅5亿年就已存在的超大质量黑洞。它的质量相当于3亿个太阳的质量,并以133亿岁"高 龄"刷新了迄今发现最古老黑洞纪录,为揭开宇宙黎明时期的奥秘打开了新窗口。相关研究成果发表于 最新一期《天体物理学杂志快报》。 天文学家借助光谱学,将光分成许多不同波长来研究物体特征。当气体绕黑洞旋转并落入黑洞时,远离 地球的气体发出的光会被黑洞拉伸成更红的波长;而靠近地球的气体发出的光则会被压缩成更蓝的波 长。这种红蓝交错的光谱成为分析遥远物体物理性质的独特武器。 研究团队此次通过分析韦布空间望远镜CAPERS项目——旨在确认和研究最遥远星系的光谱数据,发现 目标星系CAPERS-LRD-z9呈现独特的"小红点"特征。这类诞生于宇宙婴儿期(前15亿年)的星系通常 体积紧凑、色泽红艳且异常明亮。 团队表示,新发现星系有助于揭示"小红点"星系呈现明亮红色的原因。这可能是由于黑洞周围存在一团 厚厚的气体云,将穿过的光线扭曲成更红的波长。在早期宇宙中发现如此巨大的黑洞,也为研究这些天 体的演化历程提供了宝贵的机会。天文学家推测,要 ...
浙江试点分布式光伏电站气象数据上云
Ke Ji Ri Bao· 2025-08-12 02:25
Group 1 - The core point of the article is the successful cloud integration of meteorological data from the 10 kV Xiao Qiao photovoltaic power station, which is expected to enhance the renewable energy generation capacity in Zhejiang Province [1] - The meteorological data, particularly real-time irradiance information, is crucial for predicting photovoltaic power output, and the current challenges in data collection and management hinder accurate monitoring of distributed photovoltaic output fluctuations [1] - The 10 kV Xiao Qiao photovoltaic power station is the first pilot station in Zhejiang for integrating distributed photovoltaic meteorological data, equipped with micro-meteorological devices that collect nine key meteorological parameters [1] Group 2 - The company has deployed over 50 micro-meteorological devices in distributed photovoltaic stations in Chuzhou City, standardizing meteorological monitoring data formats and establishing a data mapping model for real-time synchronization to the dispatch automation system [1] - Accurate monitoring and forecasting of meteorological conditions will assist grid dispatch departments in more scientifically arranging conventional power output, reducing backup demand, and improving system operational efficiency [1] - The next steps involve deepening pilot applications, continuously optimizing data models, and promoting this model across Zhejiang Province to support the green energy transition and ensure the safe and economical operation of the power system [2]
我国新型储能装机规模全球占比超40%
Ke Ji Ri Bao· 2025-08-12 02:23
Core Insights - The report indicates that by the end of 2024, China's new energy storage capacity will reach 73.76 million kilowatts and 168 million kilowatt-hours, accounting for over 40% of the global total installed capacity [1] - The installed capacity of new energy storage projects has increased by over 130% compared to the end of 2023, with an annual addition of 42.37 million kilowatts and 101 million kilowatt-hours [1] - The average energy storage duration has increased to 2.3 hours, showing a rising trend since the start of the 14th Five-Year Plan [1] Application Effectiveness - The report highlights a significant improvement in the utilization of new energy storage in 2024, with an average equivalent utilization hours of 911 hours, an increase of approximately 300 hours compared to 2023 [1] - The average equivalent charge and discharge cycles have risen to 221 times, up by about 59 times from 2023 [1] - Several provinces, including Zhejiang, Jiangsu, Chongqing, Xinjiang, and Guangdong, have achieved average equivalent utilization hours exceeding 1,000 hours [1] Technological Landscape - As of the end of 2024, lithium-ion battery storage dominates the new energy storage technology landscape, accounting for approximately 96.4% of the installed capacity [2] - Other technologies such as compressed air storage and flow battery storage each represent about 1.0% of the total capacity [2] - Innovative technologies like gravity storage, liquid air storage, and compressed carbon dioxide storage are accelerating in application, indicating a diversified development of new energy storage technologies [2] Policy and Industry Development - The report suggests that the policy framework for new energy storage development in China has been initially established since the start of the 14th Five-Year Plan, supporting steady industry growth [2] - The diverse technological routes in new energy storage are contributing to the overall improvement in dispatch and operational levels, effectively supporting the construction of a new power system [2]