Core Insights - A new study published in "Nature Cell Biology" reveals that human cells can change their shape to close wound gaps, providing insights into cellular self-repair mechanisms and potential applications in wound healing and tissue regeneration [1] Group 1: Cellular Mechanisms - Epithelial cells, which cover internal and external surfaces of the body, play a crucial role in protecting against physical damage, pathogen invasion, and water loss [1] - The endoplasmic reticulum (ER) in epithelial cells alters its shape in response to wound curvature; it forms tubular structures at convex curves and flat sheet-like structures at concave curves [1] Group 2: Cellular Movement - The driving force at the edges of convex curves and the pulling force at concave curves change the shape of the endoplasmic reticulum through different mechanisms [1] - At the edges of convex cracks, cells extend flat membrane structures through "crawling" movements to fill the gap, while at concave edges, cells contract the edges through "tethering" movements, akin to tightening a rope to close the gap [1] Group 3: Role of Endoplasmic Reticulum - The endoplasmic reticulum reorganizes itself based on the curvature of the wound edges, influencing the migration patterns of epithelial cells, highlighting its critical role in cellular behavior [1]

Core Viewpoint - Heilongjiang Province is striving to build a national-level aerospace industry cluster, with Jiamusi positioned as a leader in the construction of a strong aerospace nation [1] Group 1: Geographic and Industrial Advantages - Jiamusi is located at a strategic latitude, allowing it to receive up to 6.5 satellite signals daily, making it an ideal site for satellite ground stations [2] - The city has established itself as a northern node in the national measurement and control network, with significant projects like the 66-meter deep space detection station supporting major space missions [2] - Over the past two years, Jiamusi has launched 21 satellite industry projects with a total investment of 4.323 billion, and an additional 31 projects are in negotiation, exceeding 4 billion [2] Group 2: Policy Support and Development Initiatives - In June, Heilongjiang Province introduced policies to support high-quality development in the aerospace industry, promoting integrated development in research, manufacturing, and services [3] - Jiamusi has also implemented city-level policies to further solidify the foundation for industrial development with substantial financial support [3] Group 3: Collaborative Efforts and Economic Acceleration - The signing ceremony at the conference included agreements with companies for satellite measurement and control ground station construction, remote sensing data application platforms, and "Aerospace + Agriculture" initiatives [4] - A commercial measurement and control station project in Fuyuan City has been initiated, with a total investment of 120 million, marking a significant expansion of previous collaborations [4] - The collaboration between Harbin Institute of Technology and Jiamusi in satellite remote sensing and smart agriculture aims to create a full-chain ecosystem from technology research to industrial service [5]

研究团队将目光聚焦于人类基因组中一类特殊区域——人类加速区（HAR）。这些区域在人类进 化过程中积累了异常多的基因突变。他们推测，正是这些快速演变的HAR区域，帮助人类获得了区别 于其他灵长类动物的独特特征。 在众多HAR区域中，HAR123脱颖而出。研究表明，这个DNA片段实际上是一个转录增强子，能够 精确调控基因的开启程度和时间。具体而言，它既能促进神经祖细胞（产生神经元和神经胶质细胞的细 胞）的发育，又能调控神经元和神经胶质细胞的比例。这种精妙的调控机制，最终造就了人类独有 的"认知灵活性"，即更新替代旧有知识的能力。 科技日报北京8月19日电 （记者刘霞）究竟是什么让人脑与众不同？美国加州大学圣迭戈分校研究 团队发现了一个名为HAR123的小型DNA片段，这将是解开人类大脑独特性之谜的关键。相关研究成果 发表于新一期《科学进展》杂志。 最新研究表明，HAR123并非普通基因，而是一个精妙的"大脑发育调控器"。它就像一位经验丰富 的指挥家，精确指导脑细胞的生成方式和比例分配。值得注意的是，人类版本的HAR123与黑猩猩的表 现大相径庭，这种差异可能赋予了人类更强大的思维和学习能力。 实验显示，在培养皿中 ...

在大足石刻宝顶山大佛湾，一场和水害斗智斗勇的"战争"已经持续多年。裂隙渗水，可诱发岩体失 稳、表层风化、盐析结晶等多重病害，对文物安全与长久保存造成严重威胁。 中国文化遗产研究院副院长李黎讲起了团队用八年时间完成的大足石刻小佛湾造像本体保护修复工 作。 考古调查研究、病害调查评估、生物病害防治、修复材料研究、效果监测评估、物理防护、石质修 复、彩绘金箔修复、结构变形加固……八年来，一项项工作扎实落地，成就今天重焕光彩的小佛湾。 李黎总结，石窟寺的保护涉及多领域多学科交叉融合，需要协同发力攻关技术难题。而且，保护理 念并非一成不变，要充分考虑文物价值、保存现状和保护需求，对石窟寺保护理念进行发展和完善。 8月19日，在河南洛阳开幕的2025石窟寺保护国际论坛上，大足石刻研究院院长蒋思维带来了多学 科协同水害治理工程的阶段性成果：工程结束后，历经五年的跟踪监测发现，卧佛表面原渗水点不再出 水，造像本体盐析现象也明显减轻，治理效果显著。 在石窟寺中治水，不用和洪水打交道，但"神出鬼没"的径流也令人头疼，传统的岩土与水利工程中 的成熟技术在石窟治水中显得有些"水土不服"。 大足石刻水害治理团队采用精细地质勘察手段，用 ...

中国科学院新疆理化技术研究所科研人员从新疆昌吉地区采集的千叶蓍全草中分离出16个倍半萜， 其中12个为新化合物。通过高分辨质谱、核磁共振波谱等方法，科研人员成功确定了这些化合物的平面 结构以及绝对构型。 记者8月18日从中国科学院新疆理化技术研究所获悉，该所资源化学研究室科研人员在对菊科蓍属 植物千叶蓍进行大量分析测试后发现，其倍半萜类成分具有抗神经炎症相关活性。这一发现为开发治疗 神经炎症疾病的相关天然先导化合物提供了坚实研究基础。相关研究成果近日发表于国际期刊《分子结 构杂志》。 据了解，千叶蓍在众多国家和地区被当作传统医药使用，可用于治疗胃肠疾病、肝胆疾病、高血 压、呼吸道感染、发热以及风湿性疾病等，还能促进伤口愈合，缓解皮肤炎症，具有良好的药用价值。 倍半萜类成分作为千叶蓍中的重要活性成分之一，因其结构丰富多样且活性优异，一直是天然药物化学 研究领域的热点，也是药物先导化合物研究的热门靶向化合物。 （原载于《科技日报》 2025-08-20 第06版） 图为千叶蓍。视觉中国供图 在进一步的研究中，科研人员利用脂多糖诱导的小胶质细胞模型，测试了化合物的抗神经炎症相关 活性。结果显示，有5个化合物可有效抑 ...

研究人员此次探索的是一种名为"电—机械重塑"的方法，其原理是许多富含胶原蛋白的组织（包括角 膜）依靠带相反电荷分子的吸引力维持形态，当在组织中施加电流时，会改变其pH值，使这些分子间 的吸引力暂时减弱，从而让组织变得柔软可塑。当pH值恢复后，组织则固定在新形态上。 实验中，12只兔眼中有10只模拟了近视情况。结果显示，这些"近视眼"在处理后均达到了预设的聚焦效 果，意味着其恢复了清晰视力。同时，研究人员通过严格控制pH值梯度，确保角膜细胞在处理后仍能 存活。进一步实验还表明，该方法能逆转部分由化学损伤造成的角膜混浊，而这一病症目前只能通过角 膜移植治疗。 尽管初步成果令人鼓舞，但研究人员强调，实验仍处在非常早期的阶段。下一步，他们将测试该方法在 不同类型屈光不正（如远视和散光）中的适用性。 （文章来源：科技日报） 不少人选择通过LASIK等激光矫正技术矫正视力。但这种手术需切削角膜组织，存在一定风险。美国加 州大学尔湾分校研究人员正在探索一种通过电流重塑角膜，而不是切割角膜的"去激光化"视力矫正新技 术。相关成果18日在美国化学会秋季年会上公布。 在最新的实验中，研究人员制作了特殊的铂金"隐形眼镜"。它们既能 ...

Core Viewpoint - Princeton University's research team has developed an innovative "curved wave" system capable of transmitting ultra-high frequency signals rapidly and stably, addressing the challenges posed by the increasing demand for data and the Internet of Things [1][2]. Group 1: Technology and Innovation - The new system utilizes a neural network to dynamically shape the transmission path of wireless signals, allowing them to bypass obstacles and maintain stable, high-speed communication [1]. - The technology focuses on the sub-terahertz frequency band, which has the potential to transmit ten times the data volume of current wireless systems, making it crucial for high-bandwidth applications such as virtual reality and fully autonomous vehicles [1]. - Traditional methods rely on external reflectors to navigate around obstacles, which are often unreliable or difficult to deploy in real-world scenarios [2]. Group 2: Methodology - The research team employs a special radio wave technology known as "Airy beams," which can propagate along curved trajectories rather than in straight lines, enabling effective transmission in non-line-of-sight conditions [2]. - A neural network is introduced to select and optimize the best curved path in real-time, similar to how professional basketball players make shooting decisions based on experience rather than complex calculations [2]. - A high-fidelity simulator was developed to allow the neural network to learn efficiently in a virtual environment, adapting to various obstacle layouts and dynamic changes [2]. Group 3: Future Implications - This work addresses a long-standing challenge in high-frequency wireless communication within dynamic environments, paving the way for future transmitters to intelligently navigate complex settings [2]. - The advancements in this technology are expected to support ultra-fast and highly reliable wireless connections for applications that are currently difficult to realize, such as immersive virtual reality and fully autonomous transportation [2].

Core Viewpoint - Recent advancements in gene editing technology, particularly through pioneering editing techniques, show promise in treating severe neurological diseases, although significant technical and funding challenges remain to be addressed [1][4]. Group 1: Breakthroughs in Gene Editing - Harvard University and Jackson Laboratory successfully utilized pioneering editing technology to correct pathogenic gene mutations in a mouse model of Alternating Hemiplegia of Childhood (AHC), achieving an 85% mutation correction rate [2]. - The treatment led to significant improvements in the mice's brain function, reducing seizure frequency and doubling their lifespan, alongside enhancements in motor and cognitive abilities [2]. - A separate team, led by Professor Qiu Zilong, demonstrated the ability to reverse behavioral abnormalities in MEF2C mutation mice using base editing technology, which is crucial for addressing epilepsy and developmental disorders in children [2][3]. Group 2: Safety and Feasibility - The precision of gene editing technology allows for targeted correction of pathogenic mutations, making it an ideal treatment for neurodevelopmental disorders and autism in children [3]. - The pioneering editing technique requires only a single brain injection for treatment, with minimal off-target effects, confirming its safety and feasibility [3]. - The technology has shown the capability to simultaneously correct five mutations, indicating its broad applicability [3]. Group 3: Challenges Ahead - Despite promising results in mouse models, significant hurdles remain before gene editing can benefit human patients, including the need for advanced delivery systems to target brain cells effectively [4]. - The use of adeno-associated virus 9 (AAV9) as a delivery vehicle poses risks of severe immune reactions at high doses, necessitating the development of improved viral vectors and exploration of non-viral delivery methods [4]. - The biotechnology sector is currently facing a funding crisis, which complicates the lengthy and complex development processes for gene therapies, potentially deterring investors [5].

记者从南方电网储能股份有限公司了解到，截至8月15日，我国首个大型锂钠混合储能站——南方电网 宝池储能站充放电量突破1亿千瓦时，有效发挥新型储能前沿技术对新能源高占比电网的保障作用，为 电力系统迎峰度夏负荷调节和新能源消纳提供有力支撑。 今年5月，占地约50亩的宝池储能站在云南文山投产，规模200兆瓦/400兆瓦时，装有52套可独立接受电 网调度的储能系统。"宝池储能站投产以来充放电量达到1.03亿千瓦时，累计启动272次，长期保持着单 日'两充两放'的高频次调用。特别是迎峰度夏期间，电站每天处于高功率运行状态，助力周边30多个风 电、光伏等新能源厂站发出的绿电稳定接入电网，相当于给电力系统增加了40万台家用空调同时开启的 调节能力。"宝池储能站站长王辉介绍。 作为我国新型储能试点示范项目，宝池储能站不仅首次实现锂、钠两种不同电力储能材料的同站性能对 比，还应用了5种差异化的构网型储能技术路线，创下自主研制应用"全球首套构网型钠离子储能系 统""全球最大单机高压直挂式构网型储能系统"等多项世界第一，推动我国储能新技术加快由试点示范 迈向成熟应用。 "我们把宝池储能站打造为服务新能源并网的'构网储能技术大擂台' ...

Core Insights - Anhui Wanrui Cold Electric Technology Co., Ltd. has developed a low-temperature refining and neon removal device that achieved helium purity of 99.99997% (6N9 grade) at a natural gas helium extraction project site in Yan'an, Shaanxi [1] - This device is the first of its kind in China to extract ultra-pure helium from natural gas, marking a significant breakthrough in the low-abundance natural gas helium extraction field [1] - Helium is a non-renewable strategic resource essential in various fields such as large scientific installations, advanced medical applications, and aerospace, often referred to as the "blood of industry" [1] Technology and Process - The research team has pioneered a new "combined method" helium extraction process that integrates four stages: hydrogen removal, membrane separation, pressure swing adsorption, and low-temperature refining [1] - The process begins with catalytic hydrogen removal to enrich helium, followed by membrane separation and pressure swing adsorption to eliminate nitrogen, methane, and other impurities, and concludes with a 30K deep low-temperature refining process to remove neon impurities [1] Operational Capacity - The device can operate continuously for 24 hours without downtime, with an annual extraction capacity of 400,000 cubic meters of high-purity helium [2]