在心血管疾病领域，70%冠心病患者面临隐匿危机-非阻塞型缺血(INOCA)，其中41%患者面临的微循环障碍，成 为冠心病精准诊疗看不见的战场。临床术者需通过测量冠脉微循环阻力水平，在术前明确微循环缺血原因、在术 后评估预后风险及手术效果。然而，现有技术或测量复杂，或测量可重复性和稳定性不足，亟需更稳定高效的创 新解决方案。 2025年6月27日，深圳北芯生命科技股份有限公司(以下简称"北芯")自主创新研发的新一代TruePhysio X无线压力 微导管正式获批国家药监局(NMPA)Ⅲ类医疗器械注册证。其作为首个国产全冠脉功能学一体化评价解决方案，既 具有冠脉心外膜血管功能评估指标(FFR/cRR)，又通过创新的多传感器自适应双点流速融合技术，实现更稳定可靠 的冠脉微循环阻力指数(iMR)测量，为冠心病精准诊疗提供"导航级"工具。 | 序号 | 受理号 | 产品名称 | 申请人 | 代理人 | 注册证编号 | 批准日期 | | --- | --- | --- | --- | --- | --- | --- | | 42 | CQZ2402181 | 一次性使用压 | 深圳北芯生命科 | | 国械注准 | 202 ...

Core Insights - The collaboration between Sesame Workshop and Maichi Culture aims to establish Sesame Street Family Entertainment Centers in China, responding to the growing demand for family-oriented entertainment experiences [2][3][5] - The family entertainment center concept focuses on immersive experiences that combine entertainment, education, and retail, catering to the needs of modern families seeking quality time together [2][3] Company Overview - Sesame Workshop has been a leader in educational entertainment since the launch of "Sesame Street" in 1969, reaching children and families in over 150 countries and winning more than 200 Emmy Awards [3][6] - Maichi Culture specializes in the introduction and management of international IP-themed entertainment projects, having established partnerships with several well-known IP brands and successfully launched various cultural projects in China and abroad [7] Market Potential - The family entertainment center market is positioned to grow significantly, as it aligns with the increasing consumer demand for high-quality family interactions and educational experiences [2][3] - The partnership is expected to create a new benchmark for family entertainment projects in China, leveraging both companies' strengths to deliver engaging and educational experiences [3][4]

Core Insights - The explosive growth of instant retail is evident, with JD.com handling an average of 25 million orders daily and Meituan's flash purchase orders increasing over 60% year-on-year in Q1 2025 [1] - The gap between daily order volumes in instant retail and e-commerce logistics is narrowing, indicating a structural transformation in the supporting logistics system [1] Group 1: Logistics Models - Instant retail mirrors the e-commerce era with two logistics models: platform self-operated and third-party delivery, with the latter gaining prominence due to its efficiency and resource utilization [1][2] - Third-party delivery services are increasingly being utilized by platforms like Meituan and Ele.me to alleviate the cost pressures associated with self-operated logistics [2] Group 2: Market Dynamics - Merchants are diversifying their platform presence to reduce dependency on single platforms, leading to a demand for third-party delivery services that can facilitate multi-platform operations [3] - The competitive landscape among platforms is driving the need for cost reduction and efficiency, positioning third-party delivery as a core infrastructure in the instant retail ecosystem [3] Group 3: Profitability and Business Models - SF Express has successfully implemented a full-scenario delivery model, achieving profitability and establishing a competitive edge through efficient resource allocation and collaboration with various platforms [4] - The increasing demand for cross-platform traffic integration and high fulfillment costs are expected to enhance the scale economy of third-party delivery services [4] Group 4: Future Outlook - The third-party delivery network enables brands to reach a broader consumer base while optimizing fulfillment costs and improving service quality, creating a win-win situation for all parties involved [5] - The instant retail market is projected to reach 2 trillion yuan by 2030, with third-party delivery potentially sharing the market with e-commerce logistics, indicating a promising future for this sector [5]

Core Viewpoint - Blockchain technology is becoming essential in financial transactions but faces unprecedented security challenges, prompting the introduction of an innovative blockchain reconstruction solution by MicroCloud Hologram (NASDAQ: HOLO) to protect transactions from malicious attacks and ensure system integrity [1] Group 1: Security Challenges and Solutions - Blockchain technology is known for its decentralization and transparency, but it also introduces new security issues, particularly in permissioned blockchains where unauthorized participants can compromise the system [1] - MicroCloud Hologram has proposed a solution using Verifiable Secret Sharing (VSS) technology, allowing for immediate blockchain reconstruction without relying on trust between different blockchain parties [1][2] - The solution includes advanced encryption techniques to ensure the security of all transaction data during transmission and storage [4] Group 2: Technical Features - An improved consensus algorithm is employed to maintain blockchain integrity and consistency even if some nodes are attacked or damaged [2][4] - VSS technology enables the splitting of secret information into multiple parts stored across different nodes, allowing reconstruction only when a sufficient number of nodes collaborate [2] - The integration of smart contracts automates the reconstruction process, reducing human intervention and enhancing efficiency and security [2][4] Group 3: Advantages of the Solution - The blockchain reconstruction solution allows for a rapid initiation of the reconstruction process during an attack, with each user capable of independent reconstruction without relying on others [5] - The use of VSS technology ensures data security during the reconstruction process, and all activities are transparent, enhancing user trust [5] - This innovative technology not only improves the security of blockchain systems but also brings greater stability and trust to the financial transaction market [5]

Core Insights - Education is a cornerstone of national development, and the smart learning hardware market is experiencing unprecedented growth due to high school entrance examination reforms and the rise of educational intelligence [1] - Hainan Xuekuibang Education has emerged as a new force in the smart education sector, leveraging a unique model that combines top academic teams, smart hardware, and comprehensive learning support services [1] Group 1: Quality of Educational Content - The reliability of an educational enterprise is primarily assessed by the quality of its research and teaching team, which at Hainan Xuekuibang Education consists of top students from Tsinghua University and Peking University [2] - These elite educators possess deep academic foundations and practical examination experience, allowing them to analyze the internal logic of high school learning and exams effectively [2] - Their recent transition from student status provides them with a profound understanding of the challenges faced by current students, enabling them to create engaging and effective teaching content [2] Group 2: Features of Xuekuibang Tablet - The Xuekuibang Tablet, a flagship product of Hainan Xuekuibang Education, offers over 7,000 meticulously recorded learning videos covering all subjects for junior and senior high school [4] - The content is categorized into various types such as thematic classes, skill classes, template classes, and sprint classes, ensuring that each student can find a suitable learning path [4] - The tablet's content is regularly updated to align with annual curriculum changes, providing students with the latest and most accurate learning materials [4] Group 3: Innovative Learning Support Model - Hainan Xuekuibang Education has introduced an innovative "dual-teacher" support model that combines artificial intelligence with human assistance, addressing the common issue of "heavy sales, light service" in the smart hardware market [5] - Students purchasing the Xuekuibang Tablet receive VIP support services, including online communication with academic planners and test analysis to identify knowledge gaps and create personalized improvement plans [5] - The presence of dedicated support teachers allows students to receive timely and effective answers to learning challenges, facilitating a smoother educational journey [5] Group 4: Bridging Educational Gaps - The increasing maturity of digital technology has amplified the influence of smart educational tools, with Hainan Xuekuibang Education successfully disseminating high-quality teaching experiences from elite institutions to broader regions [8] - This initiative breaks down geographical barriers in education, providing children in remote areas access to quality learning resources and effectively narrowing the educational equity gap [8] - Hainan Xuekuibang Education's comprehensive approach, featuring a top-tier research team, rich learning resources, innovative support services, and a customized learning system, positions it as a trusted choice for students and parents [8]

Group 1 - The domestic scrap steel market is experiencing a consolidation phase with a lack of trading activity and low procurement enthusiasm from steel companies [1] - Average procurement prices for scrap steel from key steel enterprises have decreased, with heavy scrap down by 10 CNY/ton, medium scrap down by 11 CNY/ton, and mixed scrap down by 7 CNY/ton compared to the previous week [1] - In May, the import of recycled steel raw materials was 23,600 tons, a month-on-month decrease of 24.90% and a year-on-year decrease of 5.31% [1] Group 2 - In East China, scrap steel prices remain stable, with slight decreases in procurement prices from various steel companies due to high temperatures affecting processing and transportation [2] - In Central China, the scrap steel market is weakly stable, with low inventory levels and reduced procurement prices from several steel companies [2] - In South China, the scrap steel market is under pressure, with companies reducing procurement prices to mitigate risks due to narrowing profit margins [2] Group 3 - In Southwest China, scrap steel prices are declining, with low confidence among merchants and cautious procurement by steel companies [3] - In Northwest China, scrap steel prices are slightly increasing, supported by limited market circulation resources [3] - In Northeast China, scrap steel prices are fluctuating, with steel companies adopting a cautious procurement strategy amid weak supply and demand [3] Group 4 - In North China, the scrap steel market is weak, with reduced consumption by steel companies leading to downward pressure on prices [3]

Group 1 - The ginseng industry is a key advantage for Tonghua City in Jilin Province, with a comprehensive output value of 15.694 billion yuan from January to May [1] - Tonghua City is focusing on a coordinated development strategy across the entire industry chain, enhancing the primary industry, improving secondary processing capabilities, and promoting deep processing [1][2] - The city is also innovating in the tertiary sector by developing cultural tourism and wellness industries, creating unique tourism routes and educational bases that integrate ginseng cultivation and leisure [1] Group 2 - The area for under-forest ginseng cultivation in Tonghua City is 320,900 acres, accounting for 85.40% of the province's output and 86.42% of its value [2] - There are over 450 ginseng processing enterprises in the city, with 28 large-scale production companies [2] - Tonghua has two major ginseng markets, with a projected total transaction volume of 16.5 billion yuan in 2024, where the Aoyang market accounts for over 80% of the national wild ginseng trading volume [2] Group 3 - Tonghua City is implementing a "Technology-Driven Ginseng" strategy, enhancing collaboration between industry, academia, and research [3] - The city is establishing a technology innovation center for non-forest ginseng cultivation and product development in collaboration with Changchun University of Traditional Chinese Medicine [3] - Key technologies are being developed, with significant funding allocated to projects aimed at overcoming challenges in non-forest ginseng cultivation [3]

Group 1 - The domestic steel price index slightly decreased during the week of June 23-27, with both long and flat steel price indices declining, and the drop in long steel prices being greater than that of flat steel prices [1] - The China Steel Price Index (CSPI) was 89.51 points, down 0.59 points week-on-week, a decrease of 0.65%; it fell by 1.29 points compared to the end of last month, a decline of 1.42%; and it decreased by 7.96 points since the end of last year, a drop of 8.17% [1] - The long steel price index was 91.27 points, down 0.73 points week-on-week, a decrease of 0.79%; it fell by 1.03 points compared to the end of last month, a decline of 1.12%; and it decreased by 8.95 points since the end of last year, a drop of 8.93% [1] Group 2 - All six major regions in China saw a week-on-week decline in steel price indices, with the Southwest region experiencing the largest drop and the North China and Northeast regions the smallest [2] - The North China steel price index was 88.50 points, down 0.49 points week-on-week, a decrease of 0.55%; it also fell by 13.76 points year-on-year, a decline of 13.46% [2] - The Southwest region's steel price index was 90.08 points, down 0.79 points week-on-week, a decrease of 0.87%; it decreased by 12.50 points year-on-year, a drop of 12.19% [2] Group 3 - All eight major steel product prices decreased compared to the end of last month, with the largest drop in cold-rolled sheets and the smallest in angle steel [3] - The price of 6mm high-line steel was 3243 CNY/ton, down 32 CNY/ton, a decrease of 0.98%; the price of 16mm rebar was 3051 CNY/ton, down 31 CNY/ton, a decline of 1.01% [3] - The price of 1mm cold-rolled sheets was 3721 CNY/ton, down 95 CNY/ton, a decrease of 2.49% [3] Group 4 - In May, the average import price of iron ore was 96.24 USD/ton, down 1.86 USD/ton, a decline of 1.90%; it also fell by 9.56 USD/ton year-on-year, a drop of 9.04% [4] - The domestic iron concentrate price was 843 CNY/ton, down 45 CNY/ton, a decrease of 5.07%; it decreased by 100 CNY/ton year-on-year, a drop of 10.60% [4] - Coking coal price was 1189 CNY/ton, down 89 CNY/ton, a decline of 6.96%; it fell by 731 CNY/ton year-on-year, a drop of 38.08% [4] Group 5 - In June, the CRU international steel price index was 188.1 points, down 7.0 points, a decline of 3.6%; it increased by 7.5 points since the end of last year, a rise of 4.2% [5] - The CRU long steel price index was 194.2 points, down 1.4 points, a decrease of 0.7%; it fell by 10.9 points year-on-year, a drop of 5.3% [5] - The North American steel price index was 235.1 points, down 9.9 points, a decline of 4.0%; it increased by 9.3 points year-on-year, a rise of 4.1% [5] Group 6 - The China steel price index fell below 90 points, influenced by seasonal demand fluctuations due to weather conditions affecting construction progress [6] - Supply slightly increased in the latest reporting period, while raw material prices decreased, reducing support for steel prices [6] - Overall, steel prices are expected to remain weak and fluctuate in the short term due to seasonal effects [6]

Group 1: Infrastructure Development - The G1514 Ningde to Shangrao National Highway (Ning Shang Expressway) has officially opened, with a total length of 39.741 kilometers and a design speed of 100 km/h, featuring four toll stations and three major sea-crossing bridges [1] - The Ninggu Expressway, part of the G7021 Ningde to Wuhan National Highway, has also opened, significantly enhancing transportation between Ningde and Gutian, promoting economic integration and resource sharing in the region [2] - The construction of the Xiamen-Kinmen Bridge is progressing rapidly, with the main span of the Liu Wudian Channel Bridge reaching 928 meters, expected to be completed by November, facilitating a comprehensive transportation network [3] Group 2: Project Management and Execution - The expansion project of the Shenhai Expressway from Zhangzhou to Zhaoan has reached a new phase with the successful installation of the hollow slab beams, ensuring uninterrupted traffic during construction [4] - The Zhengyong Expressway's Dehua section has commenced large-scale asphalt paving, with 5.8 million square meters completed, marking the project's advancement towards its target completion by the end of 2025 [5]

船舶产品拉动出口增长。前5个月，机电产品、石化产品强势拉动大连市出口增长。其中船舶出口98.3 亿元，同比增长58.7%，占大连市外贸出口总值的10.1%。同期，保税期货原油转口快速发展，共出口 保税原油65.8亿元，去年同期无出口记录。船舶和原油拉高大连市外贸出口增长12个百分点。 国有企业、外资企业保持增长。前5个月，大连国有企业进出口214.6亿元，同比增长16.7%。外资企业 进出口646.2亿元，同比增长11.1%。民营企业进出口1055.8亿元，同比下降0.4%。 新兴市场保持强劲势头。前5个月，大连市对马来西亚进出口保持强劲增长势头，进出口实现218.7亿 元，同比增长27.5%，继续保持大连市第二大贸易伙伴。传统市场方面，对日本进出口299.5亿元，同比 增长4.2%；对韩国进出口200.4亿元，同比增长19.3%；对沙特进出口125.4亿元，下降21.2%。(大连市 商务局供稿) 据大连海关初步统计，今年前5个月，大连市累计完成进出口总额1919.8亿元，同比增长5%，增幅高于 全国2.5个百分点，高于辽宁省6.8个百分点。其中，出口975.4亿元，同比增长17.2%；进口944.4亿元， ...