Core Insights - The new National Medical Insurance Directory has added 114 new drugs, surpassing last year's addition of 91, with 50 being first-class innovative drugs, achieving an overall success rate of 88%, an improvement from 76% in 2024 [1][2] Group 1: New Drug Additions - The total number of drugs in the directory has increased to 3,253, significantly enhancing coverage for key areas such as oncology and chronic diseases [2] - The directory includes 38 global innovative drugs and 50 first-class innovative drugs, marking a historical high for new additions [2] - Notable inclusions are the first globally approved red blood cell maturation agent, Rotecip, for treating lower-risk myelodysplastic syndromes, and the first domestically developed IL-4Rα antibody drug, Kangyueda, for multiple indications [3][4] Group 2: Oncology Innovations - Several innovative oncology drugs have been added, including Tagolizumab, the first PD-L1 monoclonal antibody approved for nasopharyngeal carcinoma, and non-covalent BTK inhibitor, Jebatib, for relapsed mantle cell lymphoma [4][5][6] - ADCs (antibody-drug conjugates) have gained attention, with new entries like Lukanasatuzumab and Ruikangquzuzumab, targeting advanced breast cancer and non-small cell lung cancer [7][8] Group 3: Chronic Disease Treatments - The directory has included innovative drugs for chronic diseases, such as Novartis' PCSK9 mRNA interference drug for cholesterol management, addressing patients who cannot reach LDL-C targets [14] - AstraZeneca's biologic drug Benralizumab for severe eosinophilic asthma has also been added, providing targeted treatment options for patients [15][16] Group 4: Influenza Treatments - The new directory has incorporated two domestic antiviral drugs for influenza, Masurashave and Angladiv, which have shown promising clinical results in reducing symptoms and viral load [17]

12月7日晚，昂瑞微（即北京昂瑞微电子技术股份有限公司；688790.SH）公布申购结果，回拨机制启动后，其网上发行最终中签率仅约为0.0345%，比摩尔 线程更难"抢"。 继摩尔线程之后，科创板成长层本月有望迎来另一家集成电路领域的京籍硬科技公司。 社保基金等"长钱"代表获配近150万股 昂瑞微0.0345%中签率水平意味着，每1万个配号里平均只有3.4个能够成功中签，比2025年12月5日刚刚上市的摩尔线程（688795.SH）申购情况还要抢手。 摩尔线程上市首日涨幅水平超过425%，这也让市场对昂瑞微登陆科创板的首日表现充满期待。 | 证券代码 | 证券简称 | | | --- | --- | --- | | 688795.SH | C摩尔-U | 20 | | 688759.SH | 必贝特-U | 20 | | 688765.SH | 木元生物-U | 20 | | 688783.SH | 西安奕材-U | 20 | 2025年内已上市的4家尚未盈利科创板成长层企业中签率等情况比较（截至2025年12月7日，数据来源：Wind） 同摩尔线程类似，从12月5日公告来看，昂瑞微本次发行的战略配售名单堪称 ...

国家发展改革委官网披露，近期国际市场油价波动运行，根据12月8日的前10个工作日平均价格与上次 调价前10个工作日平均价格对比情况，按照现行成品油价格机制，自12月8日24时起，国内汽、柴油价 格（标准品，下同）每吨均降低55元。 折合成升价，每升92号汽油、95号汽油和0号柴油的降幅分别在0.04元、0.05元和0.05元。今年国内成品 油零售价格已经经历24轮调整周期，其中7次上调，6次搁浅，11次下调。 本轮成品油零售调价周期内，国际原油价格整体呈现宽幅波动走势，受此影响，对应的原油变化率在负 值范围内低位波动。 卓创资讯成品油分析师王雪琴指出，本次下调落实后，消费者用油成本将继续减少。以油箱容量为50升 的小型私家车为例，加满一箱92号汽油将少花2元。以月跑两千公里，百公里油耗在8升的小型私家车为 例，到下次调价窗口也就是本月22日24点之前的半个月内，消费者用油成本将下降3元。物流行业，以 月跑10000公里，百公里油耗在38升的重型卡车为例，在下次调价窗口开启前，单辆车的燃油成本将减 少89元左右。 下一轮调价也将是2025自然年的最后一次调价。以当前的国际原油价格水平计算，市场人士预计，下一 轮 ...

Core Insights - The 2025 Boao Forum for Entrepreneurs, themed "Linking the World, Leading the Future: New Opportunities in the 14th Five-Year Plan," was held in Boao, Hainan, showcasing the comprehensive strength of the Wahaha Group in integrating into the new development pattern [1] - Wahaha Group's brands, including China Red Bull, Warrior, and VOSS, actively participated in various core agendas and activities during the forum, emphasizing their commitment to high-quality development [1][3] Group 1: Product Innovation and Market Response - Wahaha Group launched an upgraded Warrior energy drink series at the forum, introducing six new sugar-free flavors to meet the diverse health and taste preferences of the new generation of consumers [4][12] - The new packaging and flavors of Warrior reflect a shift towards health-conscious and personalized products, addressing the emotional value that consumers seek in their purchases [7][12] - Warrior's innovative product matrix is supported by solid research and development capabilities, including unique formulations that differentiate it in the market [7][12] Group 2: Marketing and Consumer Engagement - Warrior has integrated marketing strategies that resonate with younger consumers, focusing on immersive experiences through sponsorships and events in key areas like esports and basketball [12][14] - The brand's approach includes a seamless online and offline integration, enhancing its presence in the lives of young consumers and creating a relatable brand narrative [12][14] Group 3: Corporate Philosophy and Industry Trends - Wahaha Group's president emphasized the importance of understanding consumer emotional value as the market undergoes structural changes, shifting focus from products to services and experiences [12][13] - The company aims to align its development with national strategies and global trends, advocating for a collaborative ecosystem that fosters mutual growth among industry partners [14][15] Group 4: Cultural Exchange and Social Responsibility - The Wahaha Cultural Foundation is engaged in cultural exchange initiatives, promoting a two-way dialogue between cultures and enhancing the understanding of Chinese heritage abroad [17][19] - The foundation's projects, such as the construction of a traditional Chinese architectural landmark in Thailand, exemplify its commitment to cultural preservation and exchange [17][19]

Core Viewpoint - The article highlights the controversy surrounding liquid mask products marketed as having virus-blocking capabilities, emphasizing that these products are classified as daily necessities rather than medical devices, raising concerns about their efficacy and compliance with advertising regulations [1][10][40]. Product Classification and Claims - Liquid masks are marketed as providing physical protection by forming a barrier in the nasal cavity to block viruses and allergens, with prices ranging from tens to hundreds of yuan [2][4]. - Products like "A Dong" liquid mask claim annual sales of 1 million bottles, while other brands such as BHM and Bentrio also offer similar products [2][4]. - These products are not classified as drugs or medical devices, and their claims of preventing COVID-19 and flu viruses are considered potentially misleading [1][10]. Regulatory Concerns - There are no national standards for liquid masks, and the lack of regulatory oversight raises questions about the validity of their advertised protective claims [1][10][40]. - Experts argue that advertising these products with medical claims violates the Advertising Law of the People's Republic of China, which prohibits non-medical products from making health-related claims [10][15]. Efficacy and Testing - Many claims of high efficacy, such as "99.9% virus blockage," are based on laboratory tests rather than real-world effectiveness, leading to skepticism about their actual protective capabilities [17][24][26]. - The article notes that while some core ingredients may have demonstrated antiviral properties in studies, this does not guarantee the overall effectiveness of the final product [21][22]. Market Dynamics and Consumer Perception - Consumer reviews are mixed, with some praising the products while others criticize them as ineffective or overpriced, indicating a divide in public perception [37][40]. - The marketing strategies of these products often involve comparing them unfavorably to traditional masks, which raises ethical concerns about misleading consumers regarding their protective capabilities [35][38]. Recommendations for Industry Regulation - Experts suggest enhancing regulatory frameworks for liquid masks, including establishing unified standards and increasing oversight to prevent false advertising [40][41]. - There is a call for improved consumer reporting mechanisms to address quality issues and misleading claims in the market [42].

Core Viewpoint - Recent regulatory changes have led to a significant reduction in cooperation between local commercial banks and internet lending platforms, primarily due to concerns over "joint debt risks" and the need for banks to strengthen their own risk management capabilities [1][2][3]. Group 1: Bank Actions and Reactions - Several local banks, including Urumqi Bank and Longjiang Bank, have announced a halt to new internet lending partnerships, while others have significantly reduced the number of cooperative platforms [1]. - The introduction of new regulations has prompted banks to reassess their reliance on smaller lending platforms, which were previously favored for their lower fees and guarantees [2][3]. - Banks are now focusing on partnerships with leading platforms, reflecting a defensive strategy to mitigate potential risks associated with smaller, less reliable platforms [2][3]. Group 2: Impact on Lending Platforms - The profitability of lending platforms has been severely impacted, with profit margins dropping from approximately 4% to around 2% per loan due to regulatory changes [4][5]. - The new regulations require lending platforms to lower their comprehensive interest rates to below 24%, which poses a challenge for maintaining profitability and fulfilling guarantees [4][5]. - Increased operational costs, including rising customer acquisition costs and higher funding costs, are further straining the financial viability of many lending platforms [5][6]. Group 3: Industry Challenges and Future Outlook - The lending industry is facing a significant transformation, moving away from rapid growth towards a focus on compliance and risk management [7][8]. - Many smaller platforms may struggle to survive under the new regulatory environment, leading to a potential industry shakeout where only those with robust risk management and technological capabilities will thrive [7][8]. - The current market dynamics suggest that lending platforms must abandon previous high-risk, high-interest models and return to core lending practices to ensure long-term sustainability [8].

Core Insights - The 2025 (23rd) Influence Entrepreneur Annual Conference was held in Beijing, focusing on the theme "Emergence·Infinity - Co-creating a New Form of Intelligent Business" [1] - Over 100 prominent entrepreneurs participated in nearly 60 discussions, addressing topics such as the rise of artificial intelligence, changes in consumer environments, and how to discover new growth drivers [1][2] - The conference emphasized the transformative impact of artificial intelligence on various industries, highlighting the need for entrepreneurs to rethink value creation and organizational structures [2][7] Group 1: Artificial Intelligence and Business Transformation - The conference theme aligns with the national strategy to implement "Artificial Intelligence+" actions, which aims to accelerate scientific discovery and promote intelligent upgrades in enterprises [2] - Discussions highlighted that AI is reshaping the economic landscape and business logic at an unprecedented pace, necessitating a transformation in corporate strategies and cultures [7] - The emergence of various AI applications, particularly in the transition from large model technologies to intelligent agents, was a focal point of the discussions [6] Group 2: Industry-Specific Insights - The automotive industry is experiencing a dual advancement of oil and electric vehicles, with a notable acceleration in intelligence and export capabilities [3] - The low-altitude economy is transitioning from concept to reality, with discussions on the commercialization of low-altitude scenarios such as logistics and travel [4] - The global expansion of Chinese enterprises is evolving into a comprehensive output of technology ecosystems, value concepts, and global responsibilities [4] Group 3: Cultural Confidence and Corporate Governance - Cultural confidence is closely linked to effective corporate governance, with discussions on how to integrate cultural values into business operations [5] - Entrepreneurs shared experiences on how personal decisions can significantly impact company trajectories and individual destinies [5] - The importance of internal focus and innovation in navigating the complexities of the current global economic landscape was emphasized [8]

新京报贝壳财经讯 12月7日，广联航空（300900）发布公告称，公司收到灌南县监察委员会出具的《解 除留置通知书》，灌南县监察委员会已解除对公司控股股东、实际控制人、董事长王增夺的留置措施。 目前，王增夺已能正常履行公司法定代表人、董事长及董事会相关委员会成员等职责，公司生产经营情 况正常。董事、总经理杨怀忠不再代为履行公司法定代表人、董事长及董事会相关委员会成员等职责。 ...

新京报贝壳财经讯12月7日，古鳌科技（300551）发布公告称，公司实际控制人陈崇军正在筹划公司控 制权变更相关事宜，该事项可能导致公司实际控制人发生变更。经公司向深圳证券交易所申请，公司股 票自2025年12月8日(星期一)开市起停牌，预计停牌时间不超过2个交易日。 ...

编辑 杨娟娟 校对 杨利 新京报贝壳财经讯（记者陈维城）12月8日，Lumos Robotics鹿明机器人宣布，完成Pre-A1和Pre-A2两轮 融资，金额数亿元。其中，Pre-A1轮由鼎晖投资领投，南京创投、金景资本、金固股份跟投，Pre-A2轮 由申能诚毅投资。本轮融资将用于公司在具身智能数据和硬件领域的持续投入。 对于本轮融资，鹿明机器人创始人兼CEO喻超表示："本轮融资助力我们在具身智能的两大基础设施， 即数据和硬件这两方面深入研发、打造最好的产品和应用生态，并与生态伙伴一起，寻找最高价值的场 景进行商业化。" ...