香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確 性或完整性亦不發表任何聲明，並表明概不就因本公告全部或任何部份內容而產生或因倚賴 該等內容而引致的任何損失承擔任何責任。 WUXI APPTEC CO., LTD. * 無錫藥明康德新藥開發股份有限公司 （於中華人民共和國註冊成立的股份有限公司） （股份代號：2359） 有關完成2025年第一次回購本公司A股 及註銷本公司A股的公告 茲提述(i)無錫藥明康德新藥開發股份有限公司（「本公司」）於2025年3月17日、 2025年5月14日及2025年7月29日刊發的公告（「該等公告」）；(ii)本公司於2025年 3月26日刊發的通函；(iii)於2025年3月26日刊發的2024年股東週年大會（「2024年 股東週年大會」）通告；及(iv)於2025年4月29日刊發的2024年股東週年大會投票 結果公告，內容有關（其中包括）2025年以集中競價交易方式回購本公司A股股 份方案（「2025年第一次股份回購方案」）以及調整A股回購價格上限。除非文義 另有所指，否則本公告已界定的詞語在通函及該等公告中具有相同涵義。 本公司於2025年 ...

证券代码：603259 证券简称：药明康德 公告编号：临 2025-057 无锡药明康德新药开发股份有限公司 关于 2025 年第一次股份回购并注销实施结果暨股份变动的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： 回购方案首次披露日 2025/3/18 回购方案实施期限 2025 年 4 月 29 日~2026 年 4 月 28 日 （但受限于 公司 A 股回购一般性授权的授权期限） 预计回购金额 10亿元~10亿元 回购价格上限 114.15元/股 √减少注册资本 回购用途 □用于员工持股计划或股权激励 □为维护公司价值及股东权益 实际回购股数 11,860,809股 实际回购股数占总股本比例 0.40% 实际回购金额 1,000,003,737.59元 实际回购价格区间 65.53元/股~102.23元/股 一、 回购审批情况和回购方案内容 无锡药明康德新药开发股份有限公司（以下简称"公司"）于 2025 年 3 月 17 日召开第三届董事会第十七次会议暨 2024 年年度董事会，并于 2025 年 ...

证券代码：603259 证券简称：药明康德 公告编号：临 2025-057 无锡药明康德新药开发股份有限公司 关于 2025 年第一次股份回购并注销实施结果暨股份变动的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： | 回购方案首次披露日 | 2025/3/18 | | | | | --- | --- | --- | --- | --- | | 回购方案实施期限 | 2025 年 4 月 29 日~2026 年 4 月 | 28 | 日 | （但受限于 | | | 公司 股回购一般性授权的授权期限） A | | | | | 预计回购金额 | 10亿元~10亿元 | | | | | 回购价格上限 | 114.15元/股 | | | | | 回购用途 | √减少注册资本 □用于员工持股计划或股权激励 | | | | | | □为维护公司价值及股东权益 | | | | | 实际回购股数 | 11,860,809股 | | | | | 实际回购股数占总股本比例 | 0.40% | | | | | 实际回购金额 | ...

Summary of Key Points Core Viewpoint - The overall trading volume of the Shanghai and Shenzhen Stock Connect reached 398.83 billion, with major stocks like WuXi AppTec and Zhongji Xuchuang leading in trading volume. All sectors experienced net outflows of capital, while the ChiNext 50 ETF saw a significant increase in trading volume by 611% [1][2][4]. Trading Volume - The total trading amount for the Shanghai Stock Connect was 181.205 billion, while the Shenzhen Stock Connect was 217.626 billion [2]. Top Stocks by Trading Volume - In the Shanghai Stock Connect, WuXi AppTec ranked first with a trading volume of 29.97 billion, followed by Northern Rare Earth and Cambricon Technologies [3]. - In the Shenzhen Stock Connect, Zhongji Xuchuang led with a trading volume of 49.17 billion, followed by NewEase and CATL [3]. Sector Performance - Sectors such as CPO, rare earths, and semiconductors showed positive performance, while real estate, liquor, beauty care, and innovative pharmaceuticals faced declines [4]. Capital Flow in Sectors - All sectors experienced net outflows of capital, with the computer sector leading the outflow at 186.83 billion, followed by pharmaceuticals and electronics [6][7]. Individual Stock Capital Flow - Northern Rare Earth saw a net inflow of 27.94 billion, while Lingyi iTech experienced the highest net outflow at 28.84 billion [8][9]. ETF Trading - The Hong Kong Securities ETF had the highest trading volume at 182.27 billion, followed by the ChiNext 50 ETF at 110.43 billion [11]. - The ChiNext 50 ETF also recorded a remarkable 611% increase in trading volume compared to the previous day [12]. Futures Positioning - Among the four major futures contracts, the IF, IC, and IM contracts saw an increase in long positions, while the IH contract saw a reduction in both long and short positions [13]. Institutional Activity - Institutional buying was notable in stocks like Hengbao Co. and Bubugao, while stocks like Yuyuan Pharmaceutical and Zhongdian Xilong faced significant selling pressure [15][16]. Retail and Quantitative Trading - Retail investors showed high activity in stocks like Yuyuan Pharmaceutical and Rock Mountain Technology, while quantitative funds increased their positions in Tianrongxin and Huasheng Tiancai [18][19].

Group 1 - WuXi AppTec announced the completion of its first share repurchase and cancellation in 2025, with a total of 11.8608 million shares repurchased, accounting for 0.40% of the total share capital [1] - The actual amount spent on the repurchase was 1 billion yuan, with a price range of 65.53 yuan/share to 102.23 yuan/share [1] - All repurchased shares will be canceled, leading to a reduction in registered capital [1]

据香港交易所披露，花旗集团对无锡药明康德新药开发股份有限公司 - H股的多头持仓比例于2025年8 月21日从5.12%降至4.11%。 ...

Core Insights - As of August 27, a total of 613 stocks in the Shanghai and Shenzhen markets have experienced net outflows of main funds for five consecutive days or more [1][2] - The stock with the longest continuous net outflow is Hongchuang Holdings, with 24 days of outflows, followed by Xinrui Technology with 22 days [1] - The largest total net outflow amount is from Inner Mongolia First Machinery Group, with a cumulative outflow of 4.82 billion yuan over 10 days [1] Summary by Category Continuous Net Outflow Stocks - Hongchuang Holdings has the longest net outflow duration at 24 days [2] - Xinrui Technology follows with 22 days of net outflows [1] - Other notable stocks include Dongxin Co., with 12 days, and Changcheng Military Industry, with 10 days [1] Total Net Outflow Amount - Inner Mongolia First Machinery Group leads with a net outflow of 4.82 billion yuan over 10 days [1] - WuXi AppTec follows closely with a net outflow of 4.596 billion yuan over 9 days [1] - Wolong Electric has a net outflow of 4.098 billion yuan over 9 days [1] Proportion of Net Outflow to Trading Volume - Fangda Special Steel has the highest proportion of net outflow to trading volume, with a 11.80% outflow rate [1] - Other stocks with significant outflow proportions include WuXi AppTec at 7.42% and Wolong Electric at 5.09% [1]

Market Overview - The Shanghai Composite Index fell by 1.76% on August 27, with only one industry, communication, showing an increase of 1.66%. The beauty care and real estate sectors experienced the largest declines, down 3.86% and 3.51% respectively. The pharmaceutical and biotechnology sector also saw a decrease of 2.73% [1]. Capital Flow Analysis - The main capital outflow from both markets totaled 129.75 billion yuan, with all sectors under the Shenwan classification experiencing net outflows. The computer industry led with a net outflow of 16.31 billion yuan, followed by the pharmaceutical and biotechnology sector with a net outflow of 12.33 billion yuan. Other sectors with significant outflows included electronics, automotive, and machinery equipment [1]. Pharmaceutical and Biotechnology Sector Performance - The pharmaceutical and biotechnology sector had 474 stocks, with 36 gaining and 438 losing value. Five stocks hit the daily limit up, while one stock hit the limit down. The sector saw a net outflow of 12.33 billion yuan, with 114 stocks experiencing net inflows, and 28 stocks seeing outflows exceeding 100 million yuan [2]. Top Gainers in Pharmaceutical Sector - The top gainers in the pharmaceutical sector included: - Jimin Health: +9.97% with a net inflow of 118.04 million yuan - Nanxin Pharmaceutical: +20.00% with a net inflow of 109.05 million yuan - BGI Genomics: +0.09% with a net inflow of 106.94 million yuan [2]. Major Outflows in Pharmaceutical Sector - The stocks with the largest net outflows included: - Hengrui Medicine: -3.45% with a net outflow of 901.64 million yuan - WuXi AppTec: -1.45% with a net outflow of 482.18 million yuan - Guangsheng Tang: -10.32% with a net outflow of 378.57 million yuan [3].

Core Viewpoint - The company, WuXi AppTec, is experiencing a decline in stock price while maintaining a strong position in the CRO and CMO sectors, benefiting from the depreciation of the RMB and showing significant revenue growth in recent reports [1][3][7]. Company Overview - WuXi AppTec is a leading international open-access capability and technology platform providing comprehensive and integrated new drug research and production services for the global biopharmaceutical industry [2]. - The company is a domestic leader in the pharmaceutical outsourcing industry and has been involved in CRO and CMO services since its inception, holding over 200 authorized and pending patents [2]. - The main business focuses on the discovery, research, and production of small molecule chemical drugs, offering a full range of integrated platform services to global pharmaceutical companies [2][7]. Financial Performance - For the first half of 2025, WuXi AppTec achieved revenue of 20.799 billion yuan, representing a year-on-year growth of 20.64%, and a net profit attributable to shareholders of 8.561 billion yuan, which is a 101.92% increase year-on-year [7]. - The company's overseas revenue accounted for 78.67% of total revenue, benefiting from the depreciation of the RMB [3]. Shareholder Information - As of July 15, the number of shareholders in WuXi AppTec was 235,500, with no change in the average circulating shares per person [7]. - The company has distributed a total of 13.027 billion yuan in dividends since its A-share listing, with 9.373 billion yuan distributed over the past three years [8]. Market Activity - On August 27, WuXi AppTec's stock price fell by 1.45%, with a trading volume of 6.037 billion yuan and a turnover rate of 2.50%, resulting in a total market capitalization of 282.705 billion yuan [1]. - The stock has seen a net outflow of 441 million yuan from major funds today, with a continuous reduction in holdings over the past two days [4][5].

Summary of Conference Call Records Industry or Company Involved 1. **Gaming Industry** [3][4][6][7] 2. **CDMO (Contract Development and Manufacturing Organization)** [2][16][20] 3. **Baijiu (Chinese Liquor) Industry** [9][10][15] 4. **Chlor-alkali Industry** [2][21][22][28] Key Points and Arguments Gaming Industry 1. **Record Number of Game Approvals**: In August 2025, a total of 166 domestic games were approved, marking a historical high, with 1,050 approvals in the first eight months of the year, significantly higher than 850 in the same period last year [3][4]. 2. **Strong Performance Indicators**: High-frequency data and better-than-expected mid-year reports suggest continued growth in the gaming sector, particularly during the summer peak season [6][7]. 3. **Revenue Growth**: Tencent reported domestic and overseas game revenues of 40.4 billion yuan (up 17% YoY) and 18.8 billion yuan (up 35% YoY) respectively for Q2 2025, driven by popular titles [6]. 4. **Market Recovery**: The gaming market is showing signs of strong recovery, with significant increases in daily active users for key games, indicating a positive trend for the industry [7]. CDMO Industry 1. **Revenue and Profit Growth**: CDMO companies have shown accelerated revenue and profit growth in the first half of 2025, with a positive order trend. Notably, WuXi AppTec raised its performance guidance [16][20]. 2. **Order Backlog**: WuXi AppTec reported a backlog of 56.69 billion yuan (up 37.2% YoY) and WuXi Biologics had a backlog of 20.34 billion USD, indicating strong future revenue potential [16]. 3. **Segment Growth**: The large molecule CDMO segment is recovering, with significant growth in dual antibodies and antibody-drug conjugates (ADC) [18][19]. Baijiu Industry 1. **Asset Pricing Recovery**: The Baijiu sector is at a turning point for asset pricing recovery, with signs of demand improvement as the Mid-Autumn Festival and National Day approach [9][10][15]. 2. **Market Dynamics**: The recent rebound in Baijiu stocks is attributed to a combination of market conditions, including a bull market and improved liquidity, which may attract long-term investment [10][15]. 3. **Performance Trends**: Despite some companies reporting declines in earnings, leading brands like Kweichow Moutai have shown resilience, maintaining positive growth in revenue and net profit [12]. Chlor-alkali Industry 1. **Profitability at a Low Point**: The chlor-alkali industry is currently experiencing low profitability, with expectations for recovery driven by demand and supply-side stimuli [21][28]. 2. **Market Dynamics**: The industry is closely tied to GDP growth, with steady increases in caustic soda and PVC exports. The transition to more efficient production methods is seen as a potential growth driver [21][22]. 3. **Production Statistics**: In 2024, the domestic caustic soda production was 42.18 million tons, and PVC production was 24.68 million tons, with significant economic implications for the industry [22][23]. Other Important but Possibly Overlooked Content 1. **Investment Opportunities**: The reports highlight potential investment opportunities in specific companies within the gaming, CDMO, Baijiu, and chlor-alkali sectors, suggesting a focus on firms with strong performance indicators and growth potential [8][20][33]. 2. **Regulatory Environment**: The gaming industry is benefiting from favorable regulatory changes, while the chlor-alkali sector is facing stricter environmental regulations that could impact production methods and costs [21][31]. 3. **Long-term Trends**: The reports emphasize the importance of long-term trends in consumer behavior and market dynamics, particularly in the context of economic recovery and changing consumer preferences [15][28].