湖南方盛制药股份有限公司 HUNANFANGSHENGPHARMACEUTICALCO.,LTD. 证券代码：603998 证券简称：方盛制药 公告编号：2025-096 湖南方盛制药股份有限公司 关于公司《药品生产许可证》变更的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 一、《药品生产许可证》的变更内容 1、在生产地址湖南省长沙市麓松路789号，综合固体二车间 新增丸剂生产范围（仅用于注册申报），所在车间生产线为综合 固体二车间丸剂生产线1，上述剂型及车间生产线通过药品GMP 符合性检查后方可生产上市； 2、在生产地址湖南望城经济开发区铜官镇循环经济工业基 地内黄龙路368号的原料药车间（101车间）新增"原料药（雷美 替胺、非奈利酮、达普司他）（仅用于注册申报）"，车间生产 线为原料药车间（101车间）雷美替胺生产线、非奈利酮生产线、 达普司他生产线，上述品种转A并通过药品GMP符合性检查后方 可生产上市； 第 1页，共 3页 3、接受湖南湘雅制药有限公司委托生产黄藤素分散片（国 药准字Z20150032）、金刚 ...

Core Viewpoint - Fangsheng Pharmaceutical (603998.SH) announced that its subsidiary, Guangdong Fangsheng Jianmeng Pharmaceutical Co., Ltd., has successfully negotiated to include its proprietary product, Yao Xue Qu Feng Zhi Tong Granules, in the National Basic Medical Insurance, Maternity Insurance, and Work Injury Insurance Drug Catalog for 2025, which is expected to positively impact the product's market promotion and sales scale [1] Group 1 - The product Yao Xue Qu Feng Zhi Tong Granules is an innovative traditional Chinese medicine developed by the company [1] - This is the first time the product has been included in the 2025 Medical Insurance Catalog, which will facilitate its market access and hospital entry [1] - The inclusion is anticipated to have a positive effect on the company's future operating performance and market share, although it will not significantly impact short-term financial results [1]

Core Viewpoint - Fangsheng Pharmaceutical's subsidiary, Guangdong Fangsheng Jianmeng Pharmaceutical Co., Ltd., has successfully negotiated to include its exclusive product, Yao Xue Qu Feng Zhi Tong Granules, in the 2025 Medical Insurance Directory, which is expected to positively impact the company's future performance and market share, although the short-term effects will be limited [1] Summary by Categories Product Information - Yao Xue Qu Feng Zhi Tong Granules is classified as a Category 1.1 innovative traditional Chinese medicine and was approved for market launch on June 9, 2025 [1] - The payment standard for the product is set at 7 yuan per bag (8g), with an effective period until December 31, 2027 [1] Market Impact - The inclusion in the medical insurance directory is anticipated to have a positive effect on the company's future performance and market share [1] - There are no changes in the status of other major products, with no exits or additions reported [1]

Core Viewpoint - Fangsheng Pharmaceutical (603998.SH) announced that its subsidiary, Guangdong Fangsheng Jianmeng Pharmaceutical Co., Ltd., has successfully negotiated to include its proprietary product, Yao Xue Qu Feng Zhi Tong Granules, in the National Basic Medical Insurance, Maternity Insurance, and Work Injury Insurance Drug Catalog for 2025, which is expected to positively impact the product's market promotion and sales scale [1] Group 1 - The product Yao Xue Qu Feng Zhi Tong Granules is an innovative traditional Chinese medicine developed by the company [1] - The inclusion in the 2025 Medical Insurance Catalog will enhance the product's market access and sales potential [1] - The company anticipates a positive impact on future operating performance and market share, although no significant short-term effects on operating results are expected [1]

Group 1: Flu Season Overview - The flu season in China has entered a high incidence period, with flu-like cases in southern and northern provinces reaching 10.3% and 9.1% of total emergency visits, respectively, both higher than the previous week [1] - The demand for flu prevention and control has surged, prompting pharmaceutical companies to increase inventory and supply across all segments, including vaccines, diagnostics, treatments, and drug distribution [1] Group 2: Prevention Efforts - Hualan Biological Engineering Co., Ltd. has reported a significant increase in public awareness regarding flu vaccination, leading to a rise in demand orders from disease control centers compared to the same period last year [1] - The company has efficiently utilized its cold chain logistics to meet the vaccination needs across the country [1] Group 3: Diagnostic Solutions - Shengxiang Biotechnology Co., Ltd. has developed a rapid nucleic acid testing solution for respiratory infections, covering various pathogens and is suitable for outpatient, emergency, and inpatient settings [1] - The company has seen an increase in shipments of respiratory products since October and is well-prepared to meet the testing demand during the flu season [1] Group 4: Treatment Options - The industry is witnessing a collaborative approach in flu treatment, combining Western and traditional Chinese medicine [2] - Beijing Shuanglu Pharmaceutical Co., Ltd. has reported an increase in orders for its flu medications, including Oseltamivir and immune enhancers [2] - Hunan Fangsheng Pharmaceutical Co., Ltd. has noted a significant improvement in sales of respiratory products in the fourth quarter, although overall sales for the year still require monitoring [2] Group 5: Drug Distribution - From November, the sales of flu medications, particularly Oseltamivir and Mabalaoshuai (Sufuda), have seen significant growth at the pharmacy chain, Lao Bai Xing [3] - The company has initiated supply assurance plans ahead of the respiratory disease peak season, ensuring stable market supply through predictive measures and increased inventory [3] - The overall pharmaceutical industry is responding to the flu season by ramping up production and inventory, which not only meets public medication needs but also drives company performance [3]

Core Viewpoint - The article highlights the rising demand for flu vaccines, antiviral medications, and related testing services due to the increasing flu activity across various regions in China as winter approaches [2][6][8]. Group 1: Flu Vaccine and Antiviral Demand - The flu season is expected to drive significant growth in demand for flu vaccines, respiratory testing, and antiviral medications [2][6]. - Recent data indicates a notable increase in flu vaccine appointments and antiviral drug purchases, with some areas reporting over 500% growth in the number of buyers for antiviral medications [7][8]. - Specific antiviral drugs like Marbofloxacin have seen a remarkable increase in demand, with purchases rising over 600% in recent weeks [7]. Group 2: Market Opportunities - Analysts suggest that the current flu outbreak may lead to heightened public and market interest, creating investment opportunities in flu vaccines, virus testing, and cold medications [8]. - The demand for flu-related products is expected to surge, particularly for antiviral medications such as Oseltamivir and Marbofloxacin, as well as traditional Chinese medicine for flu treatment [8]. - The increase in flu cases is likely to boost the need for diagnostic testing, both in hospitals and for home monitoring, indicating a potential market expansion for testing products [8].

Core Insights - On November 24, 2023, brokerage firms set target prices for listed companies, with notable increases for Fangsheng Pharmaceutical, Juhua Co., and Meihua Biological, showing target price increases of 46.38%, 38.81%, and 32.68% respectively [1] Company Summaries - Fangsheng Pharmaceutical is in the traditional Chinese medicine sector and has the highest target price increase among the listed companies [1] - Juhua Co. operates in the chemical products industry and ranks second in target price increase [1] - Meihua Biological, also in the chemical products sector, ranks third with a significant target price increase [1] Brokerage Recommendations - A total of 23 listed companies received brokerage recommendations on November 24, 2023 [1] - Companies such as Keshun Co., Jinhong Group, and Meihua Biological received recommendations from one brokerage firm each [1]

Economic Overview - High-frequency data indicates that automotive consumption remains strong, benefiting from tax incentives and subsidies, while textile and film consumption is weak[7] - Real estate sales and land market show signs of fatigue, with infrastructure special bonds fully issued but project progress lagging[7] - Exports to South Korea are recovering, while import demand weakens post shopping festival[7] Market Performance - Major global asset prices have declined, with the Hang Seng Index dropping 5.1%, the largest decline among major indices[9] - The S&P 500 Index fell by 1.9%, while the Shanghai Composite Index decreased by 3.9%[9] - The 10-year U.S. Treasury yield fell by 8 basis points to 4.06%[9] Federal Reserve Insights - The U.S. added 119,000 non-farm jobs in September, significantly exceeding expectations of 51,000[12] - The unemployment rate rose to 4.4%, higher than the expected 4.3%[12] - Federal Reserve officials exhibit significant internal disagreement regarding future monetary policy direction[8] Investment Strategies - ETF inflows have increased significantly to 503 billion, while foreign and financing funds have seen outflows[15] - The market's trading activity has decreased, with average daily turnover dropping to 1.9 trillion[14] - The risk appetite remains low, with the overall market sentiment declining[14] Sector Analysis - The technology sector is expected to benefit from AI advancements, with recommendations for investments in internet and computing sectors[35] - The financial sector is poised for recovery, with a focus on brokerage and insurance stocks[35] - Consumer stocks are seen as undervalued, with potential growth in food and beverage sectors[35]

Investment Rating - The report assigns an "Accumulate" rating to the company with a target price of 16.60 CNY, compared to the current price of 11.45 CNY [5][12]. Core Insights - The company focuses on innovative traditional Chinese medicine, particularly in cardiovascular, musculoskeletal, and pediatric medication categories. It has been gradually divesting from non-core medical businesses, leading to rapid hospital admissions for key products post-collection [2][12]. - The company has successfully launched three Class 1 innovative traditional Chinese medicines, ranking among the top in the country for approved quantities. The commercial promotion of these innovative medicines is actively progressing, with significant coverage in public medical institutions [12]. - Despite short-term revenue pressure from collection policies, the company is expected to see a rebound in revenue growth in the coming years, particularly in its core cardiovascular medication segment [12]. Financial Summary - Total revenue is projected to be 1,629 million CNY in 2023, increasing to 2,020 million CNY by 2027, with a compound annual growth rate (CAGR) of approximately 9% [4][13]. - Net profit attributable to the parent company is expected to rise from 187 million CNY in 2023 to 427 million CNY in 2027, reflecting a significant growth trajectory [4][13]. - Earnings per share (EPS) is forecasted to grow from 0.43 CNY in 2023 to 0.97 CNY in 2027, indicating a strong performance outlook [4][13]. Revenue Breakdown - The cardiovascular medication segment is expected to generate revenues of 5.94 billion CNY in 2025, with a growth rate of 12% [15]. - The musculoskeletal medication segment is projected to maintain stable revenues, while pediatric medication is expected to face challenges with a projected decline in revenue [16]. - The report anticipates a decline in revenues from gynecological and anti-infection medications, while other business segments are expected to show modest growth [16][17].

Core Viewpoint - Fangsheng Pharmaceutical has experienced a significant stock price increase, with a 5.32% rise on November 14, reaching 13.06 CNY per share, and a total market capitalization of 5.734 billion CNY. The stock has risen for six consecutive days, accumulating a total increase of 5.35% during this period [1]. Company Overview - Fangsheng Pharmaceutical Co., Ltd. is located in Changsha, Hunan Province, and was established on October 13, 1997. The company was listed on December 5, 2014. Its main business includes the research, production, and sales of traditional Chinese medicine for cardiovascular and cerebrovascular diseases, orthopedic medicine, pediatric medicine, and anti-infection drugs. The revenue composition is 94.62% from product sales and 5.38% from services [1]. Shareholder Insights - Guotai Fund's Guotai Jinniu Innovation Growth Mixed Fund (020010) has entered the top ten circulating shareholders of Fangsheng Pharmaceutical, holding 3 million shares, which is 0.68% of the circulating shares. The fund has gained approximately 1.98 million CNY in floating profit today and 1.89 million CNY during the six-day price increase [2]. Fund Performance - Guotai Jinniu Innovation Growth Mixed Fund (020010) was established on May 18, 2007, with a current size of 1.494 billion CNY. Year-to-date returns are 43.83%, ranking 1608 out of 8140 in its category, while the one-year return is 34.22%, ranking 1713 out of 8056. Since inception, the fund has achieved a return of 403.92% [2]. Top Holdings - Another fund under Guotai, Guotai Juli Value Periodic Open Flexible Allocation Mixed Fund (005746), holds 89,900 shares of Fangsheng Pharmaceutical, accounting for 0.51% of the fund's net value. The fund has gained approximately 59,300 CNY in floating profit today and 56,600 CNY during the six-day price increase [4]. Fund Manager Information - The fund manager for both Guotai Jinniu and Guotai Juli is Cheng Zhou, who has a cumulative tenure of 17 years and 230 days, managing assets totaling 7.788 billion CNY. The best fund return during his tenure is 368.13%, while the worst is -37% [3][5]. Cheng Yao, co-manager of Guotai Juli, has a tenure of 4 years and 130 days, with a best return of 15.89% and a worst return of 5% [5].