Group 1 - The CRO concept stocks are experiencing a collective rebound, with the CSI Hong Kong Stock Connect Medical Theme Index rising by 2.73% as of November 24, 2025 [1] - Notable individual stock performances include Tigermed (03347) increasing over 9%, and other companies like Hansoh Pharmaceutical (03692), MicroPort Medical (00853), and WuXi AppTec (02359) also seeing gains [1][2] - The Hong Kong Medical ETF (159366) has risen over 2%, and over the past six months, it has accumulated a 29.35% increase [1][2] Group 2 - The innovative drug industry is benefiting from dual advantages of policy support and explosive demand, which are activating new drug research and development needs, positively impacting the CXO sector [3] - Among 29 listed companies in the A-share CXO sector, 20 reported year-on-year revenue growth in the first three quarters, indicating strong industry resilience [3] - WuXi AppTec's unique "integrated, end-to-end" CRDMO business model has driven steady growth, with total revenue of 32.86 billion yuan in the first three quarters of 2025, a year-on-year increase of 18.6%, and net profit attributable to shareholders rising by 84.8% to 12.08 billion yuan [3] Group 3 - The high growth of the CXO sector is supported by the trend of pharmaceutical companies outsourcing R&D and production to specialized CXO firms, which helps reduce costs and improve efficiency [4] - CXO companies are enhancing their service capabilities through continuous technological development and scale expansion, leading to deeper integration with pharmaceutical companies [4] - As of October 31, 2025, the top ten weighted stocks in the CSI Hong Kong Stock Connect Medical Theme Index accounted for 62.83% of the index, indicating a high concentration in the market [4]

资料显示，杭州泰格医药科技股份有限公司位于浙江省杭州市滨江区西兴街道聚工路19号盛大科技园A 座18层，成立日期2004年12月15日，上市日期2012年8月17日，公司主营业务涉及为国内外医药及健康 相关产品的研究开发提供专业临床研究服务,业务范围主要包括I至IV期临床试验技术服务、数据管理及 统计分析、注册申报、临床试验现场服务、SMO服务、医学检测服务、医学资料翻译、医学影像诊断 服务和培训服务。主营业务收入构成为：临床试验相关服务及实验室服务52.60%，临床试验技术服务 45.21%，其他(补充)2.19%。 泰格医药所属申万行业为：医药生物-医疗服务-医疗研发外包。所属概念板块包括：互联医疗、中盘、 融资融券、社保重仓、医疗器械等。 11月24日，泰格医药盘中上涨2.02%，截至10:24，报50.59元/股，成交1.69亿元，换手率0.59%，总市值 435.59亿元。 截至9月30日，泰格医药股东户数4.84万，较上期减少6.01%；人均流通股0股，较上期增加0.00%。2025 年1月-9月，泰格医药实现营业收入50.26亿元，同比减少0.82%；归母净利润10.20亿元，同比增长 25.4 ...

Tigermed (3347.HK) Conference Call Summary Company Overview - **Company**: Tigermed (3347.HK) - **Market Cap**: HK$33.1 billion / $4.3 billion - **Industry**: China & Korea Healthcare Services - **Current Price**: HK$38.32 - **12-Month Price Target**: HK$63.40 (Upside: 65.4%) [1] Key Points Industry and Market Context - The biotech sector presents a structural growth opportunity, supported by global R&D alignment and industry consolidation [3][18] - Domestic biotechs have not yet increased spending in clinical trials, but Tigermed's clinical registration business has begun to recover, showing a 20% year-over-year growth [2] Financial Performance - **3Q Results**: The stock initially rallied post-results due to stronger-than-expected investment income and steady order growth, but later retraced to previous levels [1] - **New Orders**: Grew at a mid-teens rate (approximately 15% year-over-year), aligning with management guidance, although no acceleration was noted [2] - **Operating Margin**: Continued pressure on operating margins, primarily due to an unfavorable mix with a rising share of lower-margin SMO services [2] - **Client Mix**: MNCs now account for about 30% of new orders, domestic large pharma close to 20%, and small biotech at 32%, down from over 50% previously [2] Investor Sentiment - Investors express cautious optimism about the biotech sector but remain hesitant to increase exposure until clearer signs of recovery emerge [3] - Concerns include expected impairment charges persisting into 4Q and perceptions of Tigermed's core-earnings valuation being relatively expensive compared to peers [3] Future Outlook - Despite challenges, growth and quality of new orders are seen as key drivers for revenue and margin improvement over the next 2-3 years [18] - The company is expected to benefit from a recovery in industry pricing in early 2026 as consolidation progresses [18] - The current valuation reflects bottoming margins, which are anticipated to normalize in 2-3 years, supported by higher clinical trial volumes and pricing recovery [18] Revenue Projections - Revenue is expected to post a 15% CAGR from 2025 to 2027, supported by net new orders growing at a mid-teens rate [19][20] - **Revenue Forecasts**: - 2024: Rmb 6,603.1 million - 2025: Rmb 6,797.4 million - 2026: Rmb 7,841.7 million - 2027: Rmb 9,007.7 million [6] Risks and Challenges - Potential risks include geopolitical factors, ongoing order impairments, and slower-than-expected global expansion [31] - The company is navigating a challenging environment with legacy low-price orders and a less favorable business mix [18] Investment Thesis - Tigermed is positioned as a market leader in China's CRO sector, with extensive project execution experience and full-spectrum R&D service capabilities [32] - The company is deepening its global footprint and enhancing service capabilities, which is expected to support long-term growth and margin resilience [32] Conclusion - Tigermed remains a compelling investment opportunity with a Buy rating, driven by robust new order momentum and improving client mix, despite current market challenges and investor caution [1][32]

Market Overview - The medical services sector experienced a decline of 2.71% on November 21, with Baihua Pharmaceutical leading the drop [1] - The Shanghai Composite Index closed at 3834.89, down 2.45%, while the Shenzhen Component Index closed at 12538.07, down 3.41% [1] Stock Performance - Notable gainers included Yangguang Nuohua, which rose by 4.47% to a closing price of 61.21, with a trading volume of 86,300 shares and a transaction value of 530 million [1] - Baihua Pharmaceutical saw a significant decline of 9.67%, closing at 9.06, with a trading volume of 292,400 shares and a transaction value of 275 million [2] - Other notable decliners included Chengda Pharmaceutical (-9.58%), Berry Genomics (-8.67%), and Guangzheng Eye Hospital (-7.26%) [2] Capital Flow - The medical services sector experienced a net outflow of 1.325 billion in institutional funds, while retail investors saw a net inflow of 1.332 billion [2] - The table of capital flow indicates that major stocks like Yangguang Nuohua had a net inflow of 10.986 million from institutional investors, while retail investors had a net inflow of 1.374 million [3]

Investment Rating - The report assigns an "Outperform" rating to Hangzhou Tigermed Consulting, indicating a positive outlook for the company's stock performance relative to the market [4][8]. Core Insights - The report highlights a recovery in performance driven by fair value net gains, with a sequential improvement in profits for the third quarter. The company is expected to benefit from a recovery in domestic demand and further supply clearance in the CRO sector, which may lead to an increase in order prices [4][8]. - Revenue forecasts for 2025-2027 are projected at 6.51 billion RMB, 7.07 billion RMB, and 7.82 billion RMB, with growth rates of -1.4%, 8.5%, and 10.7% respectively. Net profit attributable to shareholders is expected to be 1.26 billion RMB, 1.55 billion RMB, and 1.81 billion RMB, reflecting growth rates of 209.8%, 23.4%, and 17.0% [4][8]. Financial Summary - For Q3 2025, the company reported revenue of 1.78 billion RMB, a year-on-year increase of 3.86% and a quarter-on-quarter increase of 5.29%. The net profit attributable to shareholders was 637 million RMB, showing a year-on-year increase of 98.73% and a quarter-on-quarter increase of 192.42% [4][8]. - The report notes that profit recovery was primarily due to investment income and net gains from fair value changes, contributing 207 million RMB and 413 million RMB respectively [4][8]. Business Segments - The overseas clinical operations segment is experiencing rapid growth, with expectations for significant new order contributions in the second half of 2025. However, domestic clinical operations are facing challenges due to competitive pricing and order cancellations, although a gradual recovery is anticipated as low-price orders clear [4][8]. - The SMO business has shown good year-on-year growth, driven by demand from multinational pharmaceutical companies. Other segments, such as data management and statistical analysis, remain stable, while laboratory services have seen a slight decline due to intensified competition [4][8].

Core Viewpoint - The CRO sector experienced a collective decline in stock prices, influenced by recent economic data and expectations regarding interest rate changes in the U.S. [1] Group 1: Stock Performance - King’s Ray Biotechnology (01548) fell by 6.05%, trading at 14.92 HKD [1] - Kanglong Chemical (300759) decreased by 4.67%, trading at 20.8 HKD [1] - Via Biotechnology (01873) dropped by 4.57%, trading at 1.88 HKD [1] - Tigermed (300347) declined by 3.71%, trading at 36.9 HKD [1] Group 2: Economic Context - The U.S. non-farm payroll data for September exceeded expectations, leading to a reduced likelihood of interest rate cuts by the Federal Reserve in December [1] - Despite fluctuations in overseas CPI data, there is an expectation for a gradual shift towards interest rate cuts starting in 2024, which may improve investment and financing conditions [1] Group 3: Industry Outlook - Zhongtai Securities (600918) anticipates a recovery in external demand for CRO/CDMO services and domestic preclinical CROs, suggesting potential valuation recovery opportunities [1] - The CRO sector has been significantly impacted by domestic and international financing environments, but with the gradual implementation of domestic policies, a recovery in the sector is expected [1] - Continuous focus on investment opportunities in clinical CROs is recommended as the sector shows signs of recovery [1]

Core Viewpoint - The domestic R&D demand is showing marginal improvement, driven by the overseas expansion of innovative drugs, leading to a recovery in R&D orders and stabilization of industry prices after a decline in 2023. The CRO sector is expected to see better performance growth by 2026, while the CDMO industry has also reached a bottom and is poised for continued strong growth due to robust demand for new molecules and new orders [1][2][3]. CRO Sector - The domestic R&D demand is recovering, with an increase in orders and stabilization of prices, indicating a clear upward trend for CRO companies. Clinical CROs like Tigermed, Nossan, and Prasis are expected to see revenue growth turning positive by 2025, with significant contributions from overseas business [2][3]. - The recognition of domestic CRO clinical data is improving, which is beneficial for companies like Tigermed [2]. CDMO Sector - The CDMO sector has seen a recovery in performance, with new orders continuing to improve quarterly. The global demand for innovative drug R&D is driving growth in new orders and backlog [3]. - The industry is benefiting from increased capacity utilization and profitability, with a strong certainty of performance and profit growth expected to continue into 2026 [3]. Life Sciences Sector - The life sciences upstream sector is experiencing a dual drive from domestic substitution and overseas expansion, with urgent demand for domestic alternatives in areas like cell culture media and biological reagents. Companies are expected to capture market share through new product categories and cost-effective offerings [4]. - The demand for specific segments such as drug efficacy, antibodies, and proteins is increasing, indicating a clear long-term growth logic for the industry [4]. API Sector - The raw material pharmaceutical industry is currently in a phase of price bottoming and supply surplus, with traditional product performance under pressure. However, companies are extending their business into generics, innovative drugs, and specialty APIs, which may lead to value reconstruction through business structure optimization [5]. - The valuation of raw material pharmaceutical companies is at a low point, presenting opportunities based on changes in new business layouts [5]. Investment Recommendations - For clinical and preclinical CROs, companies like Tigermed, Nossan, and Yinos are recommended due to the gradual recovery of the industry and expected improvement in order structure [6]. - In the CDMO sector, companies such as WuXi AppTec, WuXi Biologics, and others with strong fundamentals and capacity advantages are highlighted for their potential benefits from industry recovery and high demand for new molecules [6]. - In the life sciences upstream sector, companies like Baitai Biotechnology and others are recommended due to accelerated domestic substitution and strong overseas growth [6]. - Companies like Pro Pharma and Huahai Pharmaceutical are noted for their new business layouts that are expected to contribute significant value increments [6].

11月20日，泰格医药盘中下跌2.00%，截至10:53，报51.32元/股，成交2.64亿元，换手率0.90%，总市值 441.88亿元。 资金流向方面，主力资金净流出2263.55万元，特大单买入253.23万元，占比0.96%，卖出287.90万元， 占比1.09%；大单买入4660.36万元，占比17.64%，卖出6889.23万元，占比26.08%。 泰格医药今年以来股价跌5.53%，近5个交易日跌13.21%，近20日跌2.49%，近60日跌22.59%。 资料显示，杭州泰格医药科技股份有限公司位于浙江省杭州市滨江区西兴街道聚工路19号盛大科技园A 座18层，成立日期2004年12月15日，上市日期2012年8月17日，公司主营业务涉及为国内外医药及健康 相关产品的研究开发提供专业临床研究服务,业务范围主要包括I至IV期临床试验技术服务、数据管理及 统计分析、注册申报、临床试验现场服务、SMO服务、医学检测服务、医学资料翻译、医学影像诊断 服务和培训服务。主营业务收入构成为：临床试验相关服务及实验室服务52.60%，临床试验技术服务 45.21%，其他(补充)2.19%。 泰格医药所属申万行业为： ...

Core Viewpoint - The announcement from Tigermed indicates that the share reduction plan by the general manager, Cao Xiaochun, has been completed, with a total of 347,600 shares reduced, which is significantly lower than the original upper limit of the plan [1] Summary by Relevant Sections - **Share Reduction Details** - Cao Xiaochun, a major shareholder and general manager, completed a share reduction plan, selling a total of 347,600 shares, which represents 0.0475% of the company's total A-share capital [1] - The reduction period has ended as of November 18, and the total shares sold are well below the planned upper limit [1] - **Impact on Company Control and Governance** - The company stated that this share reduction will not lead to any change in control and will not affect the governance structure or the ongoing operations of the company [1] - **Company Background** - Tigermed was listed on the Shenzhen Stock Exchange on August 17, 2012, and is one of the earliest CRO companies to be listed in China [1] - The company also completed a secondary listing on the Hong Kong Stock Exchange in 2020 [1]

Core Viewpoint - The announcement from Tigermed (300347) indicates that the share reduction plan by General Manager Cao Xiaochun has been completed, with a total of 347,600 shares reduced, which is significantly below the upper limit of the original plan [1] Summary by Relevant Sections Share Reduction Details - Cao Xiaochun, a major shareholder and General Manager, completed the share reduction plan on November 18, reducing a total of 347,600 shares, which accounts for 0.0475% of the company's total A-share capital [1] - The reduction was well within the limits set by the original plan, indicating a controlled approach to share divestment [1] Impact on Company Structure - The company stated that this share reduction will not lead to any change in control and will not affect the governance structure or the ongoing operations of the company [1] Company Background - Tigermed was listed on the Shenzhen Stock Exchange on August 17, 2012, and is one of the earliest listed CRO (Contract Research Organization) companies in China [1] - In 2020, the company also completed a secondary listing on the main board of the Hong Kong Stock Exchange [1]