Investment Rating - The report maintains an "Outperform" rating for the pharmaceutical and biotechnology sector [5]. Core Insights - The pharmaceutical sector has shown weaker performance compared to the overall market, with the biopharmaceutical sector outperforming with a 7.81% increase [1]. - The brain-computer interface (BCI) industry is experiencing significant breakthroughs and commercialization opportunities, driven by favorable policies and technological advancements [2][18]. - The AI healthcare market is projected to grow substantially, with the global market size expected to increase from USD 13.7 billion in 2022 to USD 155.3 billion by 2030, reflecting a CAGR of 35.5% [23][28]. Summary by Sections Market Performance - The overall A-share market increased by 4.09%, while the biopharmaceutical sector rose by 7.81%, indicating strong sector performance [1]. - The TTM price-to-earnings ratio for the biopharmaceutical sector is at 38.96x, which is at the 85.59th percentile of the past five years [1]. Brain-Computer Interface (BCI) - The BCI market is expected to see explosive growth due to policy support, including the "14th Five-Year Plan" and the establishment of independent billing codes for BCI devices [2][18]. - Key investment opportunities include upstream hardware suppliers, midstream companies with core patents, and downstream firms that create commercial applications in rehabilitation and industrial control [2][18]. AI in Healthcare - AI is identified as a critical application area in healthcare, with various themes such as AI in drug development, multi-omics, precision diagnostics, imaging devices, and smart healthcare being highlighted for investment [3][22]. - The launch of ChatGPTHealth by OpenAI signifies a growing trend in integrating AI with healthcare applications, enhancing patient interaction with health data [29]. Company Earnings Forecasts - Several companies in the sector have been rated as "Outperform," with projected net profits for 2024 ranging from CNY 1.4 billion to CNY 116.7 billion [4]. - Notable companies include Mindray Medical (CNY 116.7 billion), WuXi AppTec (CNY 93.5 billion), and Aier Eye Hospital (CNY 35.6 billion), all showing strong growth potential [4].

Core Insights - The report continues to recommend innovative drugs and the related industry chain, highlighting the strong growth potential in the pharmaceutical sector through 2026 [1][4]. Investment Strategy - The investment strategy emphasizes the focus on the CXO sector, particularly in chemical CDMO, where Chinese companies hold significant advantages in talent, chemical capabilities, compliance production, and intellectual property protection [4]. - The report suggests that the upcoming JPM conference will provide updates on the operational progress of Chinese innovative drug companies, which have shown a long-term positive development trend [4]. - The recommended investment portfolio includes A-shares such as Mindray Medical, WuXi AppTec, and Aier Eye Hospital, as well as H-shares like Kangfang Biologics and WuXi Biologics [4][5]. Industry Performance - The pharmaceutical industry experienced a decline of 4.10% in December, underperforming the CSI 300 index by 6.38% [8]. - The report notes that the chemical pharmaceutical sector saw the largest declines among sub-sectors, with a drop of 5.80% [12]. Market Data - For the period from January to November 2025, the pharmaceutical manufacturing industry's total revenue was 220.65 billion yuan, reflecting a year-on-year decrease of 2.0% [7]. - The total retail sales of consumer goods reached 45.61 trillion yuan, with retail sales of Western and Chinese medicines amounting to 660.4 billion yuan, a year-on-year increase of 1.8% [7]. Regulatory Environment - The report discusses the impact of the U.S. "Biological Safety Act," which is expected to have a limited short-term effect on Chinese CXO companies, while emphasizing the need to monitor the long-term implications of international competition and regulatory changes [22]. Recent Drug Approvals - In December 2025, a total of 16 innovative drugs or biosimilars were approved for market entry, including six domestic and ten imported products [24][25].

Summary of Shenzhen Mindray (300760.SZ) Conference Call Company Overview - Shenzhen Mindray is a leading medical device manufacturer in China, with three core segments: Patient Monitoring and Life Support (PMLS), In Vitro Diagnostics (IVD), and Medical Imaging, contributing 37%, 38%, and 20% of total revenue respectively in FY24 [24][25]. Key Industry Insights - The China medtech sector is a strategic focus for the government, driven by an aging population and increasing healthcare spending. The sector is expected to recover in 2026 after facing challenges in 2024 [3]. - Mindray's overseas business accounts for over 50% of its revenue, with a target to double market share in emerging markets within five years [1][3]. Financial Performance and Projections - **Earnings Summary**: - FY2023: Net Profit of Rmb 11,582 million, Diluted EPS of Rmb 9.558, P/E ratio of 21.3 [5]. - FY2025E: Projected Net Profit of Rmb 9,488 million, a decline of 18.7% YoY, with a P/E ratio of 26.2 [5]. - FY2026E: Expected recovery with Net Profit of Rmb 10,982 million, a growth of 15.7% YoY, and a P/E ratio of 22.6 [5]. - **Valuation**: - Target price set at Rmb 285, indicating a potential upside of 39.9% from the current price of Rmb 203.68 [6][10]. - Mindray appears undervalued compared to domestic peers, trading at approximately 23x FY26 P/E versus 38x for peers [2]. Strategic Initiatives - **Growth Acceleration**: Management anticipates a return to positive domestic growth in 2026 and further acceleration in 2027 [1]. - **Innovation Focus**: Shift towards high-end, higher-margin products and a recurring revenue model, particularly in IVD reagents [1]. - **Digital Ecosystem**: Development of integrated solutions combining equipment, IT, and AI to enhance competitive advantage [1][19]. Risks and Challenges - Potential margin pressure in FY25 due to strategic investments aimed at long-term growth [2]. - Geopolitical risks, particularly U.S.-China trade tensions, could impact revenue and sourcing [27]. - Challenges in maintaining competitive positioning if unable to adapt to technological trends and customer needs [27]. Conclusion - Mindray is positioned as a top pick in the medtech sector, with a strong growth trajectory supported by strategic initiatives and a favorable market outlook. The company is expected to leverage its leading market position to capitalize on emerging opportunities while navigating potential risks [4][25].

（文章来源：证券日报） 证券日报网讯 1月9日，迈瑞医疗在互动平台回答投资者提问时表示，公司高度重视中小投资者的利益 保护。公司将通过如下措施加强投资者利益保护：1、以业绩增长筑牢利益根基：聚焦主业，通过持续 研发投入推动技术突破，深化境内外业务布局，释放增长潜力，以高质量经营提升公司内在价值，为中 小股东利益提供根本保障。2、以稳定分红实现股东回报：公司高度重视投资者回报，在兼顾全体股东 共同利益和公司长远发展的基础上，实施可持续的利润分配政策。公司已经编制、并经股东会审议通过 了《未来三年（2025—2027年）股东回报规划》，在具备利润分配条件的前提下，公司原则上每年度至 少进行一次利润分配，公司每年以现金方式分配的利润不少于当年实现的可供分配利润的65%。自公司 2018年上市以来，公司未进行过再融资，并连续七年实施分红，累计分红总额已达到373亿元（包含回 购股份20亿元），6倍于IPO募资额59.34亿元。未来，公司将继续兼顾战略发展规划和股东回报，在保 障公司内外部业务拓展的前提下，持续加大对股东的回报力度，以此为股东创造更大的价值。3、透 明、及时的信息披露机制：公司注重信息披露的重要性、针对 ...

从资金流向上来看，当日医疗器械板块主力资金净流出6.29亿元，游资资金净流出1.68亿元，散户资金净 流入7.97亿元。医疗器械板块个股资金流向见下表： 证券之星消息，1月9日医疗器械板块较上一交易日上涨1.47%，安必平领涨。当日上证指数报收于 4120.43，上涨0.92%。深证成指报收于14120.15，上涨1.15%。医疗器械板块个股涨跌见下表： | 代码 | 名称 | 收盘价 | 涨跌幅 | 成交量(手) | 成交额(元) | | | --- | --- | --- | --- | --- | --- | --- | | 688393 | 安必平 | 33.04 | 19.71% | 15.70万 | | 4.91亿 | | 688114 | 华大智造 | 75.00 | 10.21% | 11.27万 | | 8.19亿 | | 600807 | 济高发展 | 3.47 | 10.16% | 87.79万 | | 2.93亿 | | 688358 | 祥生医疗 | 35.45 | 9.58% | 1 5.24万 | | 1.82亿 | | 688068 | 热景生物 | 205.95 | 7.28 ...

Core Insights - The cell counter industry in China is projected to reach a market size of approximately 11.24 billion yuan in 2024, with a year-on-year growth of 6.30% [1][6][8] - Traditional manual or semi-automatic counting devices are being rapidly phased out in favor of multifunctional intelligent cell analyzers that can monitor live cells and possess fluorescence analysis capabilities [1][6][8] Industry Overview - Cell counters are laboratory devices used to accurately measure the number of cells in liquid samples and analyze cell characteristics such as viability, size, morphology, and fluorescence labeling [2] - They are widely applied in fields such as biology, medicine, pharmaceuticals, cell culture, clinical diagnostics, drug screening, and cell therapy, characterized by efficiency, precision, and reduced human error [2] Industry Chain - The upstream of the cell counter industry includes raw materials and components such as lenses, filters, lasers, LED light sources, sensors, chips, and precision mechanical parts [4] - The midstream involves the production and manufacturing of cell counters, while the downstream applications span clinical diagnostics, scientific research, biopharmaceuticals, and environmental monitoring [4] Market Size - The cell counter market is a fundamental tool in the in vitro diagnostics (IVD) sector, which is expected to reach a market size of approximately 120 billion yuan in 2024, growing by 1.27% year-on-year [6] - The demand for fully automated cell counters is increasing due to the push for laboratory automation upgrades, particularly in the context of new healthcare projects [7] Key Companies - The market is characterized by a concentration of leading companies, with products from companies like Ruiwo De and Highpoint Bio being highly recognized [8] - Shenzhen Mindray Biomedical Electronics Co., Ltd. has made significant technological advancements in flow cytometry, enhancing its market position [10] Industry Development Trends 1. The technology is moving towards high integration and intelligence, evolving from mere counting tools to comprehensive intelligent analysis systems [12] 2. Market demand is shifting from general-purpose instruments to specialized solutions tailored for specific applications, leading to a more segmented market [13] 3. The industry is undergoing structural adjustments, with a focus on high-quality products and domestic alternatives gaining traction in the mid-to-high-end market [14]

Core Viewpoint - The brain-computer interface (BCI) sector is experiencing significant growth, driven by technological advancements and increased investment, particularly in the A-share market, with related stocks showing strong performance [1][5]. Group 1: Market Performance - The medical device index ETF (159898) has seen a rise of over 1.94%, with approximately 37 million yuan in net inflow as of the report [1]. - Key stocks in the BCI sector include Kewei Medical, which surged over 19%, and Shuoshi Bio, which increased over 13%, among others [3]. Group 2: Industry Growth - The global BCI market has grown from $1.2 billion in 2019 to nearly $2 billion in 2023, with a compound annual growth rate (CAGR) exceeding 13% [5]. - Projections indicate that the global BCI industry could reach $7.63 billion by 2029, with a CAGR of over 25% from 2024 to 2029 [5]. Group 3: Investment Opportunities - The BCI sector is positioned at a critical juncture with strong policy support, rapid technological iteration, and accelerated commercialization, making it a promising area for investment [8]. - The medical device index ETF (159898) tracks a broad range of medical device sectors, with leading companies like Mindray Medical and United Imaging Healthcare, providing a pure representation of the A-share medical device sector [8][9].

Core Viewpoint - The article discusses the performance of the ChiNext 50 ETF (159682) as of January 8, highlighting a decline in its value and the performance of its major holdings [1] Group 1: ETF Performance - As of the midday close, the ChiNext 50 ETF (159682) decreased by 0.92%, priced at 1.515 yuan, with a trading volume of 140 million yuan [1] - Since its inception on December 23, 2022, the fund has achieved a return of 53.15%, with a monthly return of 6.35% [1] Group 2: Major Holdings Performance - Key stocks within the ChiNext 50 ETF include: - Ningde Times: down 0.12% - Zhongji Xuchuang: down 2.72% - Dongfang Wealth: down 2.00% - Xinyi Sheng: down 1.74% - Sunshine Power: down 2.38% - Shenghong Technology: down 2.58% - Huichuan Technology: down 0.15% - Mindray Medical: up 0.33% - Yiwei Lithium Energy: down 0.72% - Tonghuashun: down 4.28% [1]

Investment Rating - The report does not explicitly state an investment rating for the industry Core Insights - The treatment equipment industry in China has experienced significant growth, with the market size increasing from 375.23 billion RMB in 2019 to 621.39 billion RMB in 2023, reflecting a compound annual growth rate (CAGR) of 13.44% [9] - The market is expected to continue growing, with projections indicating an increase to 872.09 billion RMB by 2028, at a CAGR of 6.12% [10] - The integration of AI and advanced technologies is driving innovation and efficiency in treatment devices, enhancing diagnostic accuracy and treatment precision [31] Market Background - The medical device sector includes instruments and software for diagnosis, monitoring, and treatment, with a notable increase in clinical trial institutions from 1,176 in 2022 to 1,340 in 2023, a growth of 13.8% [5] - The treatment equipment category encompasses surgical instruments and rehabilitation devices, which are crucial for patient recovery [6][7] Market Status - The treatment equipment market is expanding due to improved regulatory frameworks and increased domestic innovation, with a total of 13,260 medical device registrations in 2023, a 25.4% increase from 2022 [9] - The demand for treatment devices is rising, driven by an aging population and increased surgical procedures, with PCI surgeries growing from 915,000 in 2018 to 1,636,000 in 2023, a 26.4% year-on-year increase [13] Market Competition - The competitive landscape features a tiered structure, with leading companies like Mindray Medical and MicroPort in the first tier, and others like Qizhi Laser and Yuyue Medical in subsequent tiers [17][18] - The total R&D investment among the top 20 listed medical device companies reached 11.18 billion RMB in 2023, up 14.9% from 2022, indicating a strong focus on innovation [18] Recommended Brands - Mindray Medical is recognized for its leadership in ultrasound imaging and life information support, with a significant market share in high-end ultrasound products [19] - MicroPort specializes in minimally invasive intervention technologies, particularly in cardiovascular and neurological fields [20] - Yuyue Medical leads in home medical devices, with a dominant market position in respiratory therapy and blood glucose monitoring [22] Development Trends - The industry is undergoing a technological revolution with AI, 5G, and IoT integration, enhancing diagnostic and treatment capabilities [31] - The shift towards tiered medical services is optimizing the structure of healthcare consumption, with increased procurement of high-end devices by tertiary hospitals [32] - National policies are fostering domestic innovation and internationalization in the medical device sector, with a focus on streamlining approval processes for innovative products [33]

本报讯 （记者袁传玺）天眼查工商信息显示，近日，济南迈瑞科技有限公司成立，注册资本2000万元，经营范围含仪器仪 表制造、第一类医疗器械生产、仪器仪表销售、货物进出口、技术进出口、进出口代理等。股东信息显示，该公司由迈瑞医疗 （300760）全资持股。 （编辑 黄力） ...