迈瑞医疗是全球领先、创新驱动的世界级医疗器械企业及医疗数智化引领者。根据弗若斯特沙利文的资 料，在中国医疗器械行业，公司2024年的市值规模超过境内主要龙头企业（第二到五名）之和，工业收 入是第二名的两倍有余。按2024年的收入计，在多个领域，公司均处于行业领先地位，已有6类产品市 场份额位居全球前三，9类产品市场份额位于中国第一。 此次赴港IPO，将会是迈瑞医疗继2006年登陆纽交所、2018年回归A股后的第三次上市。 回顾此前两次上市，2006年，迈瑞医疗成功赴美上市，募资2.7亿美元，成为了中国首家在美股上市的 医疗器械企业，随后通过并购美国Datascope等公司初步拓展了全球渠道。不过，因估值考量，迈瑞医 疗选择从美股回流，在2016年私有化退市。2018年，其回归A股创业板，募资约60亿元，创下当时创业 板最大IPO纪录。 长江商报消息 迈瑞医疗（300760.SZ）持续加码国际化布局。 11月10日晚间，迈瑞医疗发布公告，公司已于11月10日向香港联交所递交了发行境外上市外资股并在香 港联交所主板挂牌上市的申请。 据公告，公司本次募集资金拟用于全球研发投入，进一步提升全球销售网络及供应链能力等。 ...

Group 1 - The Hong Kong IPO market has seen 87 new listings this year, raising over 240 billion HKD, making it the leading exchange globally for IPO fundraising [1][2] - A total of 16 A-share companies have successfully listed on the Hong Kong Stock Exchange this year, with over 80 more in the pipeline, indicating a significant trend of A+H listings [1][3] - The successful listings are predominantly from leading companies in their respective industries, with most having a market capitalization exceeding 20 billion HKD [3][4] Group 2 - Notable companies like CATL, Heng Rui Pharmaceutical, and Sai Lisi have raised substantial funds, with CATL alone accounting for over 30% of the total fundraising from A+H listed companies [4][5] - The majority of the A+H listed companies are concentrated in the technology and consumer sectors, reflecting a strategic focus on these core areas [4][9] - The performance of newly listed companies has been strong, with 12 out of 16 stocks rising or remaining stable on their first trading day [4][10] Group 3 - There has been a notable trend of H-shares trading at a premium over A-shares for some leading companies, indicating strong international investor confidence [5][9] - A record 302 companies have submitted IPO applications to the Hong Kong Stock Exchange this year, highlighting a robust interest in the market [6][8] - The influx of A-share companies seeking to list in Hong Kong is expected to enhance the quality and liquidity of the Hong Kong market [9][11]

Core Insights - The report emphasizes the investment strategy for the pharmaceutical and biotechnology industry, particularly focusing on undervalued stocks in the medical device and pharmacy sectors, which are expected to experience a valuation reversal [1][5]. - The overall investment rating for the sector is maintained at "outperform the market" [2]. Industry Overview - The pharmaceutical manufacturing industry showed a cumulative revenue of 18,211 billion yuan with a year-on-year decline of 2.0% for the first nine months of 2025 [8]. - The total profit for the industry during the same period was 2,535 billion yuan, reflecting a decrease of 0.7% [8]. - The retail sales of Western and Chinese medicines reached 535.1 billion yuan, with a growth of 1.3% year-on-year [8]. Sector Performance - In October 2025, the pharmaceutical sector experienced an overall decline of 1.83%, underperforming the CSI 300 index by the same margin [9]. - Among sub-sectors, the pharmaceutical commercial sector saw an increase of 2.81%, while the medical services sector faced a decline of 4.14% [14]. Investment Strategy - The report recommends focusing on low-valuation stocks in the medical device and pharmacy sectors, highlighting companies such as Weigao Group, Yifeng Pharmacy, and Mindray Medical [5]. - The CXO sector is identified as having global competitiveness, with a strong long-term growth trajectory [5]. Company Recommendations - The investment portfolio for November 2025 includes A-shares such as Mindray Medical, WuXi AppTec, and Yeye Medical, and H-shares like Kangfang Biologics and Kelun-Botai [5][6]. - Specific companies are highlighted for their growth potential, including WuXi AppTec, which is expected to see significant revenue growth in the coming quarters [5]. Regulatory Environment - The report tracks ongoing centralized procurement projects for medical devices, indicating a structured approach to managing costs and ensuring compliance within the industry [29].

Core Insights - The report emphasizes the investment strategy for the pharmaceutical and biotechnology industry, focusing on undervalued targets in the medical device and pharmacy sectors, which are expected to experience a valuation reversal [1][5]. - The overall investment rating for the sector is maintained at "outperform the market" [2]. Industry Performance Review - The pharmaceutical industry experienced a decline of 1.83% in October, underperforming the CSI 300 index by the same margin [9]. - The medical manufacturing sector reported a cumulative revenue of 1.8211 trillion yuan, down 2.0% year-on-year, with a total profit of 253.5 billion yuan, a decrease of 0.7% [8]. Sector Analysis - The report categorizes the CXO sector into three segments: CDMO, preclinical and clinical CRO, and generic drug CXO, highlighting the growth potential in each area [5]. - The CDMO segment shows promising growth with significant increases in new orders and emerging business areas such as peptides and oligonucleotides [5]. - The preclinical and clinical CRO segment is recovering with new order prices showing an upward trend [5]. - The generic drug CXO segment is facing challenges due to a reduced number of MAH clients and is actively seeking new growth points through innovation [5]. Investment Strategy - The report recommends focusing on undervalued medical device and distribution stocks, as well as the long-term positive trend in innovative drugs and their supply chains [5]. - A specific investment portfolio for November 2025 includes companies such as Mindray Medical, WuXi AppTec, and Aier Eye Hospital, among others [5][6]. Recent Developments - In October 2025, six innovative drugs or biosimilars were approved for market entry, indicating a robust pipeline for the industry [23][24]. - The report tracks ongoing centralized procurement initiatives for medical devices, which are expected to impact pricing and market dynamics [29]. Valuation Insights - The overall valuation of the pharmaceutical sector is currently at a PE (TTM) of 38.80, which is at the 81.52% historical percentile over the past five years, indicating a relatively high valuation compared to historical averages [17].

Investment Rating - The investment rating for the biopharmaceutical industry is "Outperform the Market" (maintained) [2] Core Insights - The biopharmaceutical industry in A-shares has shown marginal improvement in revenue and profit performance in Q3 2025, with a continued high prosperity in innovative drugs and the industry chain [6][7] - The innovative drug sector has demonstrated robust growth, with a revenue increase of 21.41% year-on-year in the first three quarters of 2025, while the CXO sector also showed significant growth [6][10] - There is a focus on undervalued turnaround targets in the medical device and pharmacy sectors, which have shown signs of stabilization and recovery [6][20] Summary by Sections Financial Summary - In the first three quarters of 2025, A-share pharmaceutical companies achieved a total revenue of 17,480.2 billion yuan, a year-on-year decrease of 1.22%, and a net profit of 1,355.8 billion yuan, down 1.00% year-on-year [6][7] - The innovative drug sector generated revenue of 485.6 billion yuan (+21.41%) and a net profit of -4.6 billion yuan, significantly reducing losses [6][10] - The CXO sector reported revenue of 698.7 billion yuan (+11.66%) and a net profit of 163.9 billion yuan (+56.78%) [6][15] Innovative Drug Sector - The innovative drug sector's revenue for Q3 2025 reached 191.7 billion yuan (+50.66%), with a net profit of 13.1 billion yuan (+155.49%) [10] - The growth in revenue is attributed to the rapid commercialization of innovative drug products and milestone payments from product licensing [10][11] CXO Sector - The CXO sector's revenue for Q3 2025 was 247.5 billion yuan (+10.03%), with a net profit of 51.1 billion yuan (+47.69%) [15] - The sector continues to show mid-to-high-speed growth, although there is some internal differentiation among companies [15] Medical Device Sector - The medical device sector reported revenue of 1,776.8 billion yuan (-2.26%) and a net profit of 265.9 billion yuan (-14.05%) in the first three quarters of 2025 [20] - The sector is expected to recover gradually, with recommendations to focus on leading companies benefiting from domestic demand and international expansion [20] Traditional Chinese Medicine Sector - The traditional Chinese medicine sector achieved revenue of 2,548.7 billion yuan (-3.58%) and a net profit of 302.6 billion yuan (-0.85%) in the first three quarters of 2025 [18] - The sector is stabilizing, with ongoing risks from national procurement policies [18] Life Sciences Upstream - The life sciences upstream sector reported revenue of 96.6 billion yuan (+7.96%) and a net profit of 8.6 billion yuan (+32.08%) in the first three quarters of 2025 [24] - The sector is expected to see improvements in demand as inventory depletion phases out and companies increase R&D investments [25]

Core Insights - The article highlights the significant net inflow of main funds into various stocks, with a total of 94 stocks experiencing a net inflow for five consecutive days or more as of November 11 [1] Group 1: Main Fund Inflows - Han's Meditech (寒武纪-U) leads with a continuous net inflow for 54 days, totaling 6.722 billion yuan [1] - Industrial and Commercial Bank of China (工商银行) follows with a net inflow of 1.225 billion yuan over 7 days [1] - The top stocks by net inflow days include: - Han's Meditech (54 days) - CITIC Bank (中信银行) (10 days) - China Communications Construction (交通银行) (8 days) [1] Group 2: Performance Metrics - Han's Meditech (寒武纪-U) has a cumulative increase of 42.40% during the inflow period [1] - Huazhong City A (华侨城A) shows a significant increase of 22.08% over the last 6 days [1] - Other notable performers include: - Wanhua Chemical (万华化学) with a 10.31% increase - China Film (中国电影) with a 34.51% increase [1] Group 3: Fund Inflow Proportions - Huazhong City A (华侨城A) has the highest proportion of net inflow to trading volume at 15.29% [1] - Other stocks with notable inflow proportions include: - Shenzhou Digital (神州数字) at 8.05% - CITIC Bank (中信银行) at 12.50% [1]

Market Overview - The medical device sector experienced a slight decline of 0.13% on November 11, with Danaher Biomedical leading the drop [1] - The Shanghai Composite Index closed at 4002.76, down 0.39%, while the Shenzhen Component Index closed at 13289.0, down 1.03% [1] Top Performers - Anxu Bio (688075) saw a closing price of 42.54, with an increase of 4.39% and a trading volume of 23,700 [1] - Nanwei Medical (688029) closed at 86.17, up 3.89% with a trading volume of 31,700 [1] - Yirui Technology (688301) closed at 109.90, increasing by 2.65% with a trading volume of 22,000 [1] Underperformers - Danaher Biomedical (920009) closed at 77.69, down 4.91% with a trading volume of 16,300 [2] - Ruimait (301367) closed at 86.41, down 4.32% with a trading volume of 18,600 [2] - Tianchen Medical (688013) closed at 52.68, down 3.59% with a trading volume of 26,900 [2] Capital Flow - The medical device sector saw a net outflow of 642 million yuan from institutional investors, while retail investors contributed a net inflow of 463 million yuan [2][3] - The top net inflows from retail investors were observed in Nanwei Medical (688029) with 46.22 million yuan, and Tianchen Medical (688013) with 24.78 million yuan [3]

Core Insights - The core initiative "Project 2025" by Mindray Medical aims to enhance global ultrasound accessibility through education, technology exchange, and research collaboration, addressing disparities in ultrasound training and resources across regions [2][3][4] Group 1: Project 2025 Achievements - Over the past three years, Mindray has established 68 ultrasound schools, benefiting thousands of medical professionals, and hosted over 2,000 academic exchanges, resulting in more than 100 published research papers [1][2] - The future goal for the next five years includes expanding training centers to 150, reaching 50,000 medical professionals, and facilitating 5,500 academic exchanges along with 300 research papers [1][7] Group 2: Global Market Position - Mindray's revenue for the first three quarters of 2025 reached 25.834 billion yuan, with a net profit of 7.570 billion yuan, highlighting significant growth in international business, which accounted for 50.6% of total revenue [4][5] - The international medical imaging product line saw high single-digit growth, with international revenue contributing 61% to this segment, and ultra-high-end ultrasound products experiencing a doubling in revenue [4][5] Group 3: Strategic Vision - "Project 2030" was launched at the ISUOG conference, continuing the focus on education, technology exchange, and research collaboration to deepen clinical research and expand regional coverage [3][7] - Mindray aims to redefine the global ultrasound landscape by creating a sustainable ecosystem that addresses clinical needs and fosters innovation through collaboration with global experts [3][7] Group 4: Market Expansion Plans - Mindray plans to enhance its presence in high-end markets, with local production projects already initiated in 11 out of 14 targeted countries [5][6] - The company has set a clear goal to double its market share in five years to match current domestic levels, indicating a strong commitment to growth in international markets [6]

Group 1 - Huayang Intelligent's shareholder, Fosun Weiying, plans to reduce its stake by up to 285.42 million shares, representing no more than 5% of the company [1] - Kangtai Biological's controlling shareholder's concerted actor, Du Xinglian, intends to reduce its stake by up to 272.4 million shares, which is no more than 0.24% of the total share capital [2] - Mindray Medical has submitted an application for H-share issuance and listing on the Hong Kong Stock Exchange [4] Group 2 - Junpu Intelligent's chairman, Liu Yuan, resigned for personal reasons, and Wang Jianfeng was elected as the new chairman [6] - Mingchen Health's actual controller and executives plan to collectively reduce their stake by up to 8.61 million shares, accounting for 3.27% of the total share capital [7] - Zhongheng Design's directors and executives plan to reduce their stake by up to 151.57 million shares, representing no more than 0.55% of the total share capital [9] Group 3 - ST Erya and its actual controller, Zheng Jiping, are still under investigation by the China Securities Regulatory Commission [10] - Qicai Chemical's shareholder, Beijing Fengyan, plans to reduce its stake by up to 399.12 million shares, accounting for 0.98% of the total share capital [11] - Aier Eye Hospital plans to distribute a cash dividend of 0.8 yuan per 10 shares to all shareholders, totaling approximately 744 million yuan [12] Group 4 - Meiri Interactive's actual controller's concerted actor plans to reduce its stake by up to 394.74 million shares, which is 1% of the total share capital [13] - Maipu Medical's pre-IPO shareholder plans to reduce its stake by up to 67.05 million shares, representing no more than 1% of the total share capital [15] - Qinchuan Machine Tool's subsidiary plans to increase its registered capital from 50 million yuan to 200 million yuan, introducing new investors [17] Group 5 - Guiyang Bank's proposed director, Yu Rui, has resigned due to work reasons [19] - Guiyang Bank plans to acquire Xifeng Development Village Bank and establish a branch [20] - Aojing Medical's directors and executives plan to collectively reduce their stake by up to 25.28 million shares, accounting for no more than 0.19% of the total share capital [21] Group 6 - Zhongji Xuchuang intends to issue H-shares and list on the Hong Kong Stock Exchange [22] - ST Huatuo's stock will have its risk warning lifted, changing its name to Shiji Huatuo [25] - *ST Gaohong's stock has been delisted from the Shenzhen Stock Exchange [27] Group 7 - Tianwo Technology plans to publicly transfer a 7.12% stake in Qinghai Haihe Railway Transportation Co., with an assessed value of approximately 8.54 million yuan [28] - Xingye Technology's major shareholder plans to reduce its stake by up to 886.65 million shares, representing no more than 3% of the total share capital [29] - Jiangnan Chemical has successfully acquired 100% equity of Chongqing Shun'an Explosive Materials Co., with a transfer base price of 1 billion yuan [31]

Market Performance - A-shares saw a rise with the Shanghai Composite Index closing up 0.53% at 4018.6 points, while the Shenzhen Component Index increased by 0.18%[1] - The Hang Seng Index in Hong Kong closed up 1.55% at 26649.06 points, with the Hang Seng Tech Index rising 1.34% and the Hang Seng China Enterprises Index up 1.90%[1] - The total market turnover in Hong Kong decreased to 2147.878 million HKD[1] Economic Indicators - The U.S. government shutdown is expected to end soon, with the Senate likely to vote on a temporary funding bill[1] - China's passenger car sales fell for the first time in over a year, with a 0.8% year-on-year decline in October due to the withdrawal of trade-in subsidies[1][12] International Trade - Switzerland is reportedly close to reaching an agreement with the U.S. to reduce export tax rates from 39% to 15%, with a potential deal expected in the next two weeks[12] - The U.S. trade representative is optimistic about reaching a trade agreement with India, which may involve lowering tariffs on Indian goods[12]