Core Viewpoint - The Hong Kong pharmaceutical sector is experiencing a significant rebound, particularly in innovative drugs, with several companies reporting strong earnings forecasts and positive growth trends [1][8]. Group 1: Innovative Drug Sector - The Hong Kong Stock Connect Innovative Drug ETF (520880) saw a rise of nearly 2% after opening lower, indicating strong investor interest [1][8]. - Innovent Biologics (诺诚健华) led the gains with a rise of over 12%, projecting revenues of 2.37 billion yuan for 2025, a year-on-year increase of approximately 134%, and an expected net profit of around 630 million yuan, marking its first profit [1][8]. - Other companies like Rongchang Biopharmaceutical and CanSino Biologics also reported profitability, with net profit growth exceeding 100% year-on-year [1][8]. Group 2: Medical Sector - The medical sector is also showing positive momentum, with AI healthcare and CXO-related stocks active; Ark Health (方舟健客) led with a 4.71% increase [3][10]. - Ark Health forecasts a profit of 7 to 10 million yuan for 2025, indicating a turnaround from previous losses, and raised approximately 144.3 million HKD to accelerate the development of its AI-driven chronic disease management platform [3][10]. - Among the 10 component stocks of the Hong Kong Stock Connect Medical ETF (159137) that disclosed earnings forecasts, 9 are expected to be profitable, with several companies anticipating net profit growth of over 100% [3][10]. Group 3: Market Trends and Investment Opportunities - Despite the positive earnings outlook, the recent performance of the pharmaceutical sector has diverged from these fundamentals, with the Hong Kong Stock Connect Innovative Drug ETF (520880) experiencing four consecutive weeks of declines [5][12]. - The current market conditions may present a favorable opportunity for accumulation in the Hong Kong pharmaceutical sector, particularly through ETFs, which offer higher efficiency and flexibility [5][12]. - Investors are encouraged to consider the Hong Kong Stock Connect Innovative Drug ETF (520880) and its associated funds for a comprehensive exposure to innovative drug companies, with the top ten holdings accounting for over 73% of the portfolio [6][12].

Market Overview - A-shares experienced volatility on February 6, with the Shanghai Composite Index closing down 0.25% at 4065.58 points, and the ChiNext Index down 0.73% [1] - The overall market turnover decreased to 2.16 trillion yuan, marking a continuous six-day decline in trading volume [1] Sector Performance - The chemical and new energy sectors led the market, while the pharmaceutical sector showed relative resilience. Consumer goods experienced a pullback, and technology continued to be sluggish [1] - The chemical ETF (516020) saw a significant inflow of 199 billion yuan, with a daily gain of 2.37% after reaching a peak increase of 3.45% during the day [2][5][6][8] Chemical Sector Insights - The chemical sector is experiencing a strong upward cycle, driven by increased demand for lithium batteries and phosphorous chemicals, with key materials seeing a surge in prices [9][10] - Major stocks in the chemical sector, such as Enjie Co., Ltd. and Zhejiang Longsheng, reported significant gains, with some stocks rising over 6% [6][8] Non-Ferrous Metals Sector - The non-ferrous metals ETF (159876) demonstrated resilience, closing up 0.18% despite initial declines, supported by over 100 billion yuan in inflows [3][11] - The sector is expected to maintain high profitability over the next 3-5 years, driven by supply-demand dynamics and macroeconomic conditions [11] Hong Kong Market Dynamics - The Hong Kong market saw a significant influx of southbound capital, with purchases reaching 133.7 billion HKD, 249.8 billion HKD, and 148.6 billion HKD over three days [4] - The pharmaceutical sector in Hong Kong showed signs of recovery, with the Hong Kong Innovation Drug ETF (520880) rising by 2% during the day, driven by strong earnings forecasts from key companies [15][16] Investment Opportunities - Analysts suggest focusing on leading companies in the chemical sector and those benefiting from rising prices, with recommendations to invest through the chemical ETF (516020) for higher efficiency [10][21] - The Hong Kong Innovation Drug ETF (520880) and the Hong Kong Medical ETF (159137) are highlighted as attractive options for investors looking to capitalize on the pharmaceutical sector's growth [20][21]

Group 1: JPM Conference Overview - The J.P. Morgan Healthcare Conference is one of the largest and most influential gatherings in the global healthcare sector, covering pharmaceuticals, biotechnology, medical devices, diagnostics, digital health, and healthcare services [3] - The conference serves as a platform for multinational corporations (MNCs), biotech firms, and investment institutions to connect, providing clear signals for industry development over the coming year [4] - The 2026 JPM Conference will be held from January 12 to 15 in San Francisco, California [5] Group 2: MNC Strategic Positioning and BD Strategies - In 2026, MNCs are focusing on four key areas: neuroscience, immunology, oncology, and cardiovascular diseases [6] - Business development (BD) transactions are becoming a core strategy for MNCs, with a shift towards precision and rationality in BD deals, emphasizing next-generation immunotherapies, cell therapies, and gene therapies [6] - AI is increasingly integrated into drug development, clinical design, and operational management across the industry [6][18] Group 3: Investment Opportunities in Innovative Drugs - The acceleration of BD transactions abroad is expected to inject new performance growth and market value elasticity, with a notable increase in projects and upfront payments in 2025 [8] - Policy support for innovative drugs is improving, with recent measures from health authorities aimed at fostering high-quality development in the sector [8] - Key clinical data releases and commercialization milestones for several innovative drugs are anticipated in 2025, which could significantly impact market valuations [8] Group 4: Key Domestic Companies and Their Focus - Companies like Hengrui Medicine and BeiGene are expected to achieve significant milestones in 2026, including multiple new drug applications and clinical data releases [24][25] - Hengrui Medicine aims to leverage a dual strategy of R&D and BD, with over 25 ongoing Phase III clinical trials and a target of more than 10 new drug approvals [24] - BeiGene is positioned to capitalize on its leading products in the chronic lymphocytic leukemia (CLL) space, with several key regulatory submissions and clinical trials planned for 2026 [29][35]

Core Viewpoint - The China Securities 1000 Enhanced ETF (159680) has shown a positive performance with a 0.96% increase in value, reaching 1.681 yuan, and a trading volume of 50.22 million yuan as of the midday close on February 6 [1] Group 1: Fund Performance - The fund's performance benchmark is the China Securities 1000 Index return rate [1] - Since its establishment on November 18, 2022, the fund has achieved a return of 66.24% [1] - The fund has recorded a return of 6.24% over the past month [1] Group 2: Top Holdings - Key holdings in the fund include: - O-film Technology: down 0.10% - Yiyuan Communication: up 0.14% - Zhenyu Technology: up 7.53% - Jucheng Technology: down 1.00% - Tiannai Technology: up 1.51% - Rongchang Biology: up 2.44% - Nanxin Technology: up 0.12% - Aikedi: down 0.47% - Huayang Group: up 0.03% - Maiwei Biology: up 0.89% [1]

证券分析师 022-28451618 SAC NO：S1150511010016 cuijian@bhzq.com 晨会纪要（2026/02/06） 市场处于震荡整固阶段，结构性行情将是重点——A 股市场 2026 年 2 月投资 策略报告 行业研究 关注年报业绩催化与创新药械产业链——医药生物行业 2 月投资策略展望 崔健 渤海证券研究所晨会纪要（2026.02.06） 宏观及策略研究 晨会纪要（2026/02/06） 宏观及策略研究 市场处于震荡整固阶段，结构性行情将是重点——A 股市场 2026 年 2 月投资策略报告 请务必阅读正文之后的声明 渤海证券股份有限公司具备证券投资咨询业务资格 1 of 6 要 宋亦威（证券分析师，SAC NO：S1150514080001） 云计算提价印证高景气，AI 应用迎来多点催化——计算机行业 2 月投资策略 展望 证 券 研 究 报 告 晨 会 纪 严佩佩（证券分析师，SAC NO：S1150520110001） 靳沛芃（研究助理，SAC NO：S1150124030005） 1、宏观方面 2026 年年初，出口端在结构优化、产品竞争优势以及经贸环境改善的支撑下将 ...

Investment Rating - The report maintains a "Buy" rating for Rongchang Biologics (09995) with a target price of HKD 136 [1] Core Insights - The report is optimistic about the company's upcoming milestones, including the enrollment of MGIII for Taitasip and the initiation of SSIII, as well as the first overseas BLA submission for Vedisit and the data readout for 1LUCIII [1] - The inclusion of Taitasip's indications in the mainland's medical insurance is expected to drive significant sales growth, alongside the anticipated approvals for major indications like SS and IgAN [1] - Early-stage products (RC148, RC118, new ADCRC278) are progressing towards more indications, with data readouts likely to continue catalyzing the stock price [1] Financial Performance - Rongchang Biologics has issued a positive earnings forecast, expecting approximately RMB 3.25 billion in revenue for the previous year, representing a year-on-year growth of about 89% [1] - The net profit is projected to be around RMB 716 million, with a non-deductible net profit of approximately RMB 78.5 million, both showing a turnaround from losses year-on-year [1] - The performance significantly exceeded previous expectations from both the report and the market, with the timing of the profitability inflection point occurring earlier than previously anticipated [1] - Excluding contributions from external licensing and fair value gains, the report estimates that the company's core business achieved or approached breakeven in the fourth quarter, ahead of prior expectations [1] - With Taitasip and RC148 expanding internationally and more R&D costs being borne by overseas partners, there is optimism for further improvement in the company's profit margins this year [1]

智通财经APP获悉，花旗发布研报称，在暂停评级一段时间后，重新给予荣昌生物(09995)"买入/高风 险"评级，目标价为105港元。因集团与艾伯维就PD-1/VEGF双特异性药物RC148达成合作，进一步拓展 其管线候选药物的全球潜力。 总体而言，花旗认为此次业务拓展合作展示了荣昌生物创新资产的高品质及其业务发展能力，但考虑到 PD-1/VEGF领域及全身型重症肌无力领域的激烈竞争，认为其全球商业化进程仍存在不确定性。花旗将 荣昌生物上述合作的6.5亿美元首付款计入今年收入，并预估RC148经风险调整后的峰值销售额为27亿 美元。 花旗认为，合作完成后，市场焦点应转移至基于临床数据和竞争格局的未来全球三期临床研究及商业化 潜力。关于泰它西普的全球开发，其治疗全身型重症肌无力的三期临床研究顶线数据或于2027年上半年 公布，而针对干燥症的三期临床试验将于今年上半年启动。泰它西普在国内的销售趋势积极，公司管理 层目标于2026年实现收支平衡。 ...

股份發行人及根據《上市規則》第十九B章上市的香港預託證券發行人的證券變動月報表 截至月份: 2026年1月31日 狀態: 新提交 致：香港交易及結算所有限公司 公司名稱: 榮昌生物製藥（煙台）股份有限公司 呈交日期: 2026年2月5日 I. 法定/註冊股本變動 | 1. 股份分類 | 普通股 | 股份類別 | H | | 於香港聯交所上市 (註1) | | 是 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 證券代號 (如上市) | 09995 | 說明 | | | | | | | | | | 法定/註冊股份數目 | | | 面值 | | 法定/註冊股本 | | | 上月底結存 | | | 208,581,239 | RMB | | 1 RMB | | 208,581,239 | | 增加 / 減少 (-) | | | 0 | | | RMB | | 0 | | 本月底結存 | | | 208,581,239 | RMB | | 1 RMB | | 208,581,239 | | 2. 股份分類 | 普通股 | 股份類別 | A | ...

Industry Overview - The report highlights the recent release of the "Implementation Regulations of the Drug Administration Law of the People's Republic of China" and the issuance of opinions by nine departments to promote high-quality development in the drug retail industry [21][23][25] - The sixth batch of national procurement for high-value medical consumables has been opened for bidding, indicating ongoing efforts to regulate and enhance the medical supply chain [21][22] Industry Data - In December, the Consumer Price Index (CPI) for healthcare was 101.8, with a year-on-year increase of 1.8% and a month-on-month increase of 0.1% [26] - The Producer Price Index (PPI) for pharmaceutical manufacturing was 96.1, showing a year-on-year decrease of 3.9% and a month-on-month decrease of 0.2% [37] - For the entire year of 2025, the cumulative operating income of the pharmaceutical manufacturing industry was 24,870.0 billion, a year-on-year decrease of 1.2%, while the cumulative total profit was 3,490.0 billion, a year-on-year increase of 2.7% [39] Company Announcements - Hengrui Medicine received drug registration approval and had several drugs included in the list of breakthrough therapy designations, indicating a strong pipeline and regulatory progress [62][67] - Zai Lab entered a global strategic cooperation and licensing agreement with AbbVie for the development and commercialization of ZG006, which includes significant upfront and milestone payments [68] - Rongchang Bio signed an exclusive licensing agreement with AbbVie for RC148, a dual-specific antibody drug, which includes substantial upfront and potential milestone payments [69] Market Performance - In January, the Shanghai Composite Index rose by 3.76%, while the Shenzhen Component Index increased by 5.03%. The SW Pharmaceutical and Biological Index rose by 3.14%, with all sub-sectors showing positive growth [74] - The SW Pharmaceutical and Biological Industry's price-to-earnings ratio (TTM) was 50.97, with a valuation premium of 258% relative to the CSI 300 [77] Monthly Strategy - The report suggests focusing on investment opportunities in innovative drugs, CXO, and upstream life sciences, particularly in light of recent developments in brain-computer interfaces and AI applications [84] - The report maintains a "neutral" rating for the industry and recommends a "buy" rating for Hengrui Medicine and an "accumulate" rating for WuXi AppTec [84]

近日，阿斯利康公司一款治疗系统性红斑狼疮的生物制剂阿伏利尤单抗（anifrolumab）的三期临床试验 结果显示，针对亚洲成年中重度系统性红斑狼疮患者，与安慰剂组相比，在降低疾病活动度和减少口服 糖皮质激素用量方面均显示出统计学和临床意义上的改善。 阿斯利康援引数据称，全球约有超过340万的系统性红斑狼疮患者，其中，中国的疾病负担最重，患者 人数约100万，创新药市场前景广阔。 红斑狼疮创新疗法研发壁垒高，是全球公认的药物研发"黑洞"，此前，包括优时比、强生、礼来在内的 多家制药巨头都有过研发失败经历。 系统性红斑狼疮（SLE）作为一种自身免疫性疾病，目前尚无法治愈。长期以来，针对该疾病的创新疗 法也备受关注。 尽管红斑狼疮目前尚无法治愈，但该疾病可以长期控制。目前，针对狼疮肾炎的治疗主要是基于激素联 合免疫抑制剂的⽅案。口服糖皮质激素虽常用于缓解疾病症状，但长期使用会引发严重的全身性副作 用，且无法针对疾病核心发病机制进行精准干预，导致患者往往难以实现充分的疾病控制并达到缓解。 红斑狼疮创新疗法研发壁垒高，是全球公认的药物研发"黑洞"，此前，包括优时比、强生、礼来在内的 多家制药巨头都有过研发失败经历。 2 ...