昭衍新药 20250429 摘要 • 昭衍新药一季度营收 4.11 亿元，同比增长 115.11%，扣非归母净利润 2,566.26 万元。实验室板块亏损 4,134.38 万元，主要受季度因素和行业 压力影响；生物资产价值变动收益 5,300 万元，资金管理贡献 1,662.3 万 元。需关注实验室板块利润压力及行业竞争态势。 • 一季度新签订单约 4.3 亿元，同比增加，在手订单 22 亿元，与上季度持 平。订单取消情况减少，客户状态回归正常。关注新签订单的持续性和在 手订单的执行情况，以及客户信誉度对现金流的影响。 • 国内 IND 数量增速放缓至 2.54%，但仍维持高位，订单价格稳定。FDA 拟用 AI 和类器官替代动物实验，短期内影响有限，需关注国内外政策推进 及技术差距，以及对公司长期战略的影响。 • 猴价稳定，受供需关系影响。国内实验用猴供给稳定，供需平衡偏紧。关 注猴价波动对实验室服务板块利润的影响，以及公司对实验用猴供应的策 略调整。 • 非临床业务产能利用率高，广州设施竣工验收。公司积极进行国内外收并 购，关注实验室服务能力。美国子公司 Bellmore 及离岸外包业务发展稳 定，离岸外 ...

Core Viewpoint - WuXi AppTec (药明康德) has reported significant growth in its Q1 2025 financial results, with revenue and net profit reaching historical highs, driven by increased production capacity and operational efficiency [2][4]. Financial Performance - In Q1 2025, WuXi AppTec achieved revenue of 96.55 billion yuan, a year-on-year increase of 20.96%, and net profit of 36.72 billion yuan, up 89.06% [2][4]. - The company’s ongoing business orders reached 523.3 billion yuan as of March 31, 2025, reflecting a 47.1% year-on-year growth [3][10]. Business Segments - The TIDES (oligonucleotide and peptide) business generated revenue of 22.4 billion yuan in Q1 2025, marking a substantial year-on-year increase of 187.6% [3][10]. - The chemical business reported revenue of 73.91 billion yuan, up 32.87% year-on-year, with over 460,000 new compounds synthesized and delivered in the past 12 months [9]. - The small molecule D&M (Development and Manufacturing) business achieved revenue of 38.5 billion yuan, a 13.8% increase year-on-year [9]. Operational Efficiency - WuXi AppTec has optimized production processes and operational efficiency, contributing to improved profitability [4][10]. - The company has successfully passed FDA inspections for its Changzhou and Taixing API bases, with plans to increase small molecule API reactor capacity to over 4,000 KL by the end of 2025 [9]. Future Outlook - WuXi AppTec maintains its annual guidance, expecting a revenue growth of 10% to 15% for its ongoing business in 2025 [11].

Investment Rating - The report maintains a "Buy" rating for WuXi AppTec (603259) [2] Core Insights - WuXi AppTec reported a significant revenue increase of 21.0% year-on-year, reaching 9.65 billion yuan in Q1 2025, with a notable 89.1% growth in net profit attributed to one-time investment gains [5][8] - The company has a strong order backlog of 52.33 billion yuan, reflecting a 47.1% year-on-year increase, with TIDES orders growing by 105.5% [8] - The company plans to distribute a special dividend of 1 billion yuan in addition to maintaining a 30% annual cash dividend ratio, alongside a share buyback of 1 billion yuan [8] Financial Data and Profit Forecast - Total revenue projections for 2025 are estimated at 42.77 billion yuan, with a year-on-year growth rate of 9.0% [7] - The forecasted net profit for 2025 is 11.27 billion yuan, representing a 19.3% increase compared to the previous year [7] - The report anticipates a continued double-digit growth trajectory for the company's core business, with overall revenue expected to reach between 41.5 billion and 43 billion yuan [8]

Financial Performance - Revenue for Q1 2025 reached RMB 3,099 million, a 16.0% increase from RMB 2,671 million in Q1 2024 [9] - Net profit attributable to shareholders was RMB 306 million, up 32.5% from RMB 231 million in Q1 2024 [9] - Non-IFRS adjusted net profit increased by 3.1% to RMB 349 million from RMB 339 million [9] - Operating cash flow for Q1 2025 was RMB 853 million, a 14.4% increase from RMB 746 million in Q1 2024 [9] Revenue Composition - Revenue from China delivery business grew by 15.7% [11] - Revenue from overseas delivery business increased by 18.3% [11] - Laboratory services contributed 60% to revenue, with clinical research services at 14% and CDMO at 22% [11] - Revenue from top 20 pharmaceutical companies grew by 29.1% [14] Customer Growth - Revenue from North American clients increased by 16.8% [12] - Revenue from European clients rose by 26.6% [12] - Revenue from Chinese clients grew by 13.1% [12] Cost and Margin Analysis - Gross margin for laboratory services improved to 45.5% in Q1 2025 from 44.1% in Q1 2024 [17] - Gross margin for clinical services increased to 11.8% from 9.3% [19] - Gross margin for large molecule services improved despite being in a construction phase [20] Strategic Outlook - The company aims for a revenue growth target of 10-15% for the full year 2025 [33] - The company emphasizes the importance of health demand and technological innovation in driving industry growth [33]

2024 年，公司仿制药业务受集采、MAH 制度等政策的影响，营业收入下降，2024 年实现收入8.02 亿 元，同比下降21.18%；归母净利润-0.53 亿元，同比下降119.39%；扣非归母净利润-0.73 亿元，同比下 降128.07%。25Q1实现收入1.29 亿元，归母净利润-0.26 亿元，扣非归母净利润-0.36 亿元。 盈利预测与评级：我们预计公司2025-2027 年收入分别为7.04/7.78/8.75 亿元，同比增 长-12.2%/10.6%/12.4%；归母净利润分别为0.55/1.03/1.19 亿元，同比增长204.4%/87.9%/15.0%。考虑到 公司受政策影响短期业绩不确定性加大，短期利润承压，但25 年有望扭亏，下调至"增持"评级。 风险提示：成果转化不及预期，新签订单不及预期，行业竞争加剧。 截至24 年底，自主研发项目已经立项尚未转化的自主研发项目近300 项，完成小试阶段91 项，完成中 试放大阶段53 项，在验证生产阶段78 项，2024年研发成果技术转化58 个。创新驱动技术转化，新药研 发团队已逾200 人，截至年报披露公司已取得1 类新药的2 个IND 批 ...

NO.1 赛力斯向港交所递交上市申请 4月28日，港交所文件显示，赛力斯集团股份有限公司向港交所提交上市申请书。今年3月底，赛力斯就宣布拟赴港上市，其彼时表示，发行H 股股票并上市是为了深入推进全球化战略布局，打造国际化资本运作平台，提高综合竞争力。H股募资将用于新能源汽车技术研发、海外市场 拓展及供应链优化。 点评：此次赴港上市旨在打造国际化资本运作平台，提高综合竞争力。H股募资将用于新能源汽车技术研发、海外市场拓展及供应链优化，这 将有助于赛力斯在全球新能源汽车市场中占据更有利的位置。 NO.2 昭衍新药一季度业绩同比扭亏为盈 4月28日，昭衍新药（HK06127，股价15.26港元）公布2025年第一季度业绩，公司实现营业收入约2.87亿元，同比减少11.54%；归属于上市公司 股东的净利润约4111.95万元，同比扭亏为盈；基本每股收益0.05元。公告称，净利增长主要系上年同期生物资产公允价值变动损失较多所致。 点评：尽管昭衍新药一季度营业收入有所下降，但净利润实现扭亏为盈，主要得益于上年同期生物资产公允价值变动损失的减少。这表明公司 在成本控制和运营效率方面取得了一定成效。 NO.3 耀才证券金融复 ...

但随着这个瓜的剧情发酵，舆情开始关注起了那位被医生搞大肚子的董医生，她的经历有些特殊。 父亲是某央企的总经理\党委副书记（副厅级），母亲是北京211高校的副院长（副处级），女儿高中就去美国读书，之后在哥伦比亚大学读了 一个经济学本科。 到这其实都还算正常，但之后回国通过协和4+4项目，四年后获得医学博士学位（M.D.）。看到这估计很多人就懵逼了，之前还是经济学本 科，回国读4年就变成医学博士了？ 我一开始也以为是通过父母权力寻租开的后门，结果去搜了一下发现协和这个4+4项目，专门收 非医学 类本科毕业生，但是要求本科是全球前 100的名校毕业，这个董医生是符合的，另外需要有2位医学领域的副教授写推荐信，学费也不便宜，一年15万。每年招30-45人。 感觉这个项目...是专门给背景人士的孩子留的后门，海外本科和高昂学费把普通家庭筛掉了，还要2个副教授写推荐信，这要不是在那个圈子里 的可不好找。 普通医学生的路径是5+3+3，5年本科，3年专硕，后面再规培3年当苦力。相比之下这位董医生国外回来4年就拿到博士学位，规培时间也压缩 到1年，之后就临床做手术了，而且还是在北京知名医院工作，直接把普通医学生羡慕坏了。 最 ...

Core Viewpoint - 凯莱英 (002821) reported a robust growth in revenue and profit margin for Q1 2025, with a year-on-year revenue increase of 10.1% and a net profit increase of 15.8%, leading to an "overweight" rating from Tianfeng Securities [1][2]. Financial Performance - In Q1 2025, the company achieved a revenue of 1.541 billion yuan and a net profit of 327 million yuan, with gross profit margin and net profit margin at 42.5% and 21.2% respectively [2]. - The net profit growth rate outpaced revenue growth by 5.7 percentage points, indicating effective cost control measures [3]. Cost Control and Efficiency - The company implemented cost reduction and efficiency improvement measures, resulting in a decrease in all expense ratios year-on-year and quarter-on-quarter [3]. - Sales expenses were 44.15 million yuan with a sales expense ratio of 2.9%, down 0.3 percentage points year-on-year and 1.7 percentage points quarter-on-quarter [3]. - Management expenses totaled 184 million yuan with a management expense ratio of 11.9%, down 0.4 percentage points year-on-year and 5.5 percentage points quarter-on-quarter [3]. - R&D expenses were 138 million yuan with a ratio of 8.9%, down 3.2 percentage points year-on-year and 1.1 percentage points quarter-on-quarter [3]. Business Segments - The small molecule CDMO business remained stable with a gross profit margin of 45.17%, and 12 projects expected to reach the PPQ stage in 2025 [3]. - Emerging business revenue grew over 80% year-on-year, with a gross profit margin of 33.05%, indicating a recovery compared to the previous year [3]. - The company plans to add a new OEB5 facility and R&D building to support the growing demand for toxin-linker projects [3]. Employee Incentives - The company launched a restricted stock incentive plan, granting 4.896 million shares at a price of 37.52 yuan per share to 648 individuals, including directors and key personnel [4]. - The plan includes performance-based vesting conditions tied to revenue and profit growth targets from 2025 to 2028 [4]. Profit Forecast and Investment Rating - The company forecasts revenues of 6.617 billion yuan, 7.617 billion yuan, and 8.782 billion yuan for 2025, 2026, and 2027 respectively, with net profits of 1.114 billion yuan, 1.310 billion yuan, and 1.532 billion yuan [5]. - The investment rating remains "overweight" based on the positive financial outlook and growth potential [5].

证券代码：300404 证券简称：博济医药 博济医药科技股份有限公司 投资者关系活动记录表 | | □特定对象调研 □分析师会议 | | --- | --- | | 投资者关系活 | □媒体采访 □业绩说明会 | | 动类别 | □新闻发布会 □路演活动 | | | □现场参观 | | | ■其他（投资者电话交流会） | | 参与单位名称 | | | | 招商证券、开源证券、华安证券、申万宏源、信达证券、光大证 券、兴业证券、东北证券、太平洋证券、华鑫证券、银河证券、 | | | 华福证券、国泰海通、华创证券、源阖投资、健顺投资、华源医 | | | 药、中信资管、磐松私募、国联民生、尚诚资产、华西医药、鸿 | | 及人员姓名 | 运私募、宜宾发展创投、九祥资产、星允投资、平安证券、中泰 | | | 证券、杭贵投资、泰山财保、香港沪光国际投资、大家资产、明 | | | 达资产、天驷资产、前海明辉、中融汇信、中航赛维 | | 时间 | 2025 年 4 月 27 日（星期日） | | 地点 | 广州 | | 上市公司接待 | 董事长、总经理：王廷春 | | 人员姓名 | 副总经理、财务总监：欧秀清 | | | 副 ...

Group 1 - The core viewpoint emphasizes the ongoing reforms and opening-up initiatives in Shanghai, particularly in the Pudong New Area, aimed at enhancing its role as a leading area for modern socialist construction and high-level institutional opening-up [2][4]. - The Shanghai International Business Cooperation Zone is under construction, expected to become one of the most open regions internationally [1]. - The Shanghai Auto Show in 2025 attracted nearly 1,000 renowned enterprises from 26 countries and regions, showcasing over a hundred new models, reflecting confidence in China's vast market and development [1]. Group 2 - The "One Industry, One License" reform has significantly streamlined the process for businesses, reducing the time to open a store from over 20 days to just a few hours, allowing a coffee chain to open 130 new stores in a year [3]. - The establishment of a joint regulatory mechanism for special biomedical items in Shanghai has facilitated the first cross-border transport and use of CAR-T cell therapy in the country, demonstrating the effectiveness of policy innovation [4]. - Shanghai has developed 23 local regulations and 34 management measures to support market entities and enhance the legal framework for business operations, contributing to a more favorable business environment [6].