Group 1: Company Research - The company, CSPC Pharmaceutical Group (01093), is rated as "Buy" with a target price of HKD 10.03, representing a potential upside of 31.3% from the current price of HKD 7.64[5][6]. - The market capitalization of CSPC Pharmaceutical Group is HKD 880.32 billion, with 11.522 billion shares issued[5]. - The adjusted net profit for the first three quarters of 2025 decreased by 15.2%, with revenue at HKD 19.89 billion, down 12.3% year-on-year[6]. Group 2: Financial Performance - The gross profit margin for the company is 65.6%, with a decrease in sales and administrative expense ratios by 4.4 and 0.8 percentage points to 31.1% and 3.1%, respectively[6]. - R&D expenses as a percentage of revenue increased by 6.3 percentage points to 27.1%[6]. - The net profit attributable to shareholders was HKD 3.51 billion, down 7.1%, with a net profit margin of 15.5%, a decrease of 2.1 percentage points[6]. Group 3: Segment Performance - The revenue from the finished drug segment was HKD 15.45 billion, down 17.2%, with a 25.5% decline in drug revenue to HKD 13.91 billion[6][7]. - The raw material drug segment saw revenue of HKD 1.79 billion, up 22.3%, while the functional food segment reported revenue of HKD 1.43 billion, up 11.2%[6][7]. - The profit margin for the finished drug segment was 20.9%, down 1.8 percentage points, while the vitamin C segment's profit margin increased by 3.6 percentage points to 11.0%[6][7]. Group 4: Future Outlook - The company plans to maintain dividends in the second half of the year at least at the same level as the first half, which was HKD 0.14 per share[6]. - The target market value for CSPC Pharmaceutical Group is estimated at HKD 116.5 billion, with a corresponding price-to-earnings ratio of 25.2 times for 2025 and 29.4 times for 2026[9].

两份药品清单，让新药、好药更加触手可及。 聚焦临床急需、医保可负担——进医保的114种药品中，有36个肿瘤用药、12个糖尿病等慢性病用药、 13个抗感染类药品、10个罕见病用药等，29种临床用不上、或有更好替代的药品被调出目录。 一些能够弥补基本医保保障空白的药品进入医保目录，用于治疗三阴性乳腺癌的芦康沙妥珠、胰腺癌用 药伊立替康脂质体、套细胞淋巴瘤用药匹妥布替尼片等"救命药"入围；一年仅需两针就可以有效降低血 脂水平的英克司兰钠、糖尿病用药替尔泊肽等慢性病新药也进了医保。 此次调整中，一款用于治疗KRAS靶点肺癌的新药格外引人关注，这款药有多新？它在2025年5月刚刚 获批。 查询新版医保药品目录，不乏刚获批不久的新药，如流感用药昂拉地韦片、玛舒拉沙韦片等。此次调整 有50种药品为一类创新药，创新药正以更快速度惠及患者。 人力资源社会保障部工伤保险司司长郑玄波介绍，此次调整后，新版国家医保目录内药品总数增至3253 种，其中西药1857种、中成药1396种。 近年来，医保目录持续扩容，但部分救急、救命的创新药在刚上市时价格高昂，基本医保目录难以覆 盖，不少患者依然难以负担。 新华财经广州12月8日电（记者彭 ...

一年一度的国家医保药品目录调整，始终牵动着万千百姓的心。 12月7日，在2025创新药高质量发展大会上，新版国家医保药品目录及首版商保创新药目录正式发布，114种药品成功纳入医保、19种新药进 商保创新药目录，对参保人"药篮子"全面升级。 人力资源社会保障部工伤保险司司长郑玄波介绍，此次调整后，新版国家医保目录内药品总数增至3253种，其中西药1857种、中成药1396 种。 近年来，医保目录持续扩容，但部分救急、救命的创新药在刚上市时价格高昂，基本医保目录难以覆盖，不少患者依然难以负担。 今年，对这些患者来说，也许希望能够被重新定义。 聚焦创新程度高、临床价值大、患者获益显著且超出基本医保保障范围的创新药，商保创新药目录纳入了CAR-T、TCE疗法、双特异性抗体 等靶点肿瘤药物，也有短肠综合征、戈谢病等罕见病药物，阿尔茨海默症治疗药物等，共计19种新药。 两份药品清单，让新药、好药更加触手可及。 聚焦临床急需、医保可负担——进医保的114种药品中，有36个肿瘤用药、12个糖尿病等慢性病用药、13个抗感染类药品、10个罕见病用药 等，29种临床用不上、或有更好替代的药品被调出目录。 一些能够弥补基本医保保障空 ...

海通国际发布研报称，维持石药集团(01093)"优于大市"评级与目标价11.34港元，前三季度营收同比有 所下滑，但第三季度单季业绩已显现回暖迹象，成药收入环比增长10%，归母净利润同比增长27%，公 司通过加大研发投入并优化销售费用，积极推动创新药放量及资产出海(如SYS6010等)，管理层对2026 年成药业务恢复正增长及未来BD成果持乐观态度。 海通国际主要观点如下： 业绩表现 -神经系统收入19.1亿元(同比-4%，环比+4%) -抗肿瘤收入5.9亿元(同比-47%，环比+19%) -抗感染收入8.3亿元(同比-9%，环比+12%) 9M25石药集团实现收入199亿元(同比-12%)，其中成药收入155亿元(同比-17%)，原料药收入30亿元(同 比+10%)，功能食品及其他业务14亿元(同比+11%)。公司实现毛利率65.6%(同比下滑4.9ppts)；研发费用 42亿元(同比+8%)，研发费用率21.0%(同比提高3.9ppts)；销售费用率24.1%(同比减少5.1ppts)。前三季度 石药集团实现归母净利润35亿元(同比-7%)。管理层预计2026年成药销售有望恢复正增长，但同时也表 示仿制药 ...

智通财经APP获悉，海通国际发布研报称，维持石药集团(01093)"优于大市"评级与目标价11.34港元， 前三季度营收同比有所下滑，但第三季度单季业绩已显现回暖迹象，成药收入环比增长10%，归母净利 润同比增长27%，公司通过加大研发投入并优化销售费用，积极推动创新药放量及资产出海(如SYS6010 等)，管理层对2026年成药业务恢复正增长及未来BD成果持乐观态度。 海通国际主要观点如下： 业绩表现 -呼吸系统收入3.2亿元(同比+73%，环比+28%) -消化代谢收入2.5亿元(同比+14%，环比+8%) 9M25石药集团实现收入199亿元(同比-12%)，其中成药收入155亿元(同比-17%)，原料药收入30亿元(同 比+10%)，功能食品及其他业务14亿元(同比+11%)。公司实现毛利率65.6%(同比下滑4.9ppts)；研发费用 42亿元(同比+8%)，研发费用率21.0%(同比提高3.9ppts)；销售费用率24.1%(同比减少5.1ppts)。前三季度 石药集团实现归母净利润35亿元(同比-7%)。管理层预计2026年成药销售有望恢复正增长，但同时也表 示仿制药集采续约规则目前仍有不确定性。 ...

Investment Rating - The report maintains an "Outperform" rating for CSPC Pharmaceutical Group [2][12][23] Core Insights - In 9M25, CSPC achieved revenue of CNY 19.9 billion, a year-on-year decrease of 12%, with finished drug revenue at CNY 15.5 billion, down 17% year-on-year [3][16] - The gross profit margin (GPM) was reported at 65.6%, a decline of 4.9 percentage points year-on-year [3][16] - Management anticipates a return to positive growth in finished drug sales by 2026, despite uncertainties surrounding the renewal rules for generic drug procurement [3][16] Financial Performance Summary - Revenue projections for FY25 and FY26 have been adjusted to CNY 27.3 billion and CNY 30.1 billion, respectively, reflecting slower-than-expected out-licensing income recognition [9][23] - Net profit attributable to shareholders is forecasted at CNY 5.0 billion for FY25 and CNY 5.1 billion for FY26, down from previous estimates [9][23] - The company reported a net profit of CNY 3.5 billion in 9M25, a decrease of 7% year-on-year [3][16] Segment Performance - In 3Q25, all segments of finished drugs showed quarter-on-quarter improvement, with total finished drug revenue reaching CNY 4.7 billion, an increase of 8% quarter-on-quarter [5][18] - Notable revenue contributions in 3Q25 included CNY 1.91 billion from the nervous system segment and CNY 0.32 billion from the respiratory system, which saw a 73% year-on-year increase [21][18] Research and Development - R&D expenses for 9M25 were CNY 4.2 billion, an increase of 8% year-on-year, with an R&D expense ratio of 21.0% [3][16] - The company is advancing multiple clinical pipelines, including SYS6010, with clinical data expected to be released in 2026 [20][22] Out-Licensing Opportunities - The report highlights significant potential for out-licensing multiple assets, including SYS6010, which is progressing well in clinical trials [6][19] - The company's business development strategy is entering a phase of tangible results, with expectations for continuous deals that will enhance net profit [6][19]

Core Viewpoint - The report from CMB International indicates that the revenue of CSPC Pharmaceutical Group in the third quarter was 6.62 billion yuan, slightly below expectations, but showed significant improvement compared to the second quarter, with a more pronounced recovery expected in the fourth quarter [1] Revenue and Growth Forecast - The management anticipates a return to positive growth by 2026, driven by key new products such as Mingfule, Irinotecan Liposome, and biosimilars (Omalizumab and the upcoming Pertuzumab) [1] - By 2027, growth expectations are expected to become clearer as the impact of centralized procurement dissipates [1] Research and Development - As the innovative pipeline progresses into late-stage clinical development, R&D expenses are projected to increase rapidly [1] Financial Adjustments - Based on the third-quarter performance and management outlook, the revenue forecasts for 2025 to 2027 have been reduced by 5% to 8%, and net profit forecasts have been lowered by 16% to 21% [1] - The target price has been adjusted to 7.3 HKD, with the company facing both positive catalysts and risks in the short term, leading to a reasonable stock valuation and a "Neutral" rating [1]

Core Viewpoint - The report from Open Source Securities highlights that CSPC Pharmaceutical Group (01093) is intensifying its focus on innovation, establishing eight major technology platforms, and has over 130 projects in its pipeline, indicating a period of concentrated value realization for its innovations [1] Financial Projections - The firm forecasts the net profit attributable to the parent company for 2025-2027 to be 4.915 billion, 5.272 billion, and 5.714 billion yuan respectively, with EPS projected at 0.4, 0.5, and 0.5 yuan, corresponding to PE ratios of 21.4, 20.0, and 18.4 times [1] Innovation and Collaborations - CSPC has achieved multiple external licensing agreements for several innovative products in recent years, including Lp(a), MAT2A, ROR1ADC, and irinotecan liposome, with expected revenue recognition from these licenses in 2025 [1] - The company is currently in discussions with international pharmaceutical firms regarding various innovative drug projects, including a collaboration with AstraZeneca in June to co-develop a new oral small molecule candidate using an AI-driven drug discovery platform [1] - In July, CSPC announced the global licensing of its small molecule GLP-1 receptor agonist SYH2086 to Madrigal Pharmaceuticals, which includes a $120 million upfront payment [1] R&D Platform and Growth Potential - The company's R&D platform is entering a realization phase, and the achievement of multiple licensing agreements is expected to become its second growth curve [1]

Core Viewpoint - The report from Kaiyuan Securities highlights that CSPC Pharmaceutical Group (01093) is intensifying its focus on innovation, establishing eight major technology platforms, and has over 130 projects in its pipeline, indicating that the value of its innovations is entering a concentrated realization phase [1] Financial Projections - The company is expected to achieve net profit attributable to shareholders of 4.915 billion, 5.272 billion, and 5.714 billion yuan for the years 2025 to 2027, respectively [1] - Earnings per share (EPS) are projected to be 0.4, 0.5, and 0.5 yuan for the same years, with corresponding price-to-earnings (PE) ratios of 21.4, 20.0, and 18.4 times [1] Innovation and Collaborations - CSPC has recently entered into multiple external licensing agreements for several innovative products, including Lp(a), MAT2A, ROR1 ADC, and irinotecan liposome, with expected revenue recognition from these licenses in 2025 [1] - The company is actively negotiating licensing agreements for various innovative drug projects with international pharmaceutical companies, including a collaboration with AstraZeneca in June to develop a new oral small molecule candidate driven by AI [1] - In July, CSPC announced the global licensing of its small molecule GLP-1 receptor agonist SYH2086 to Madrigal Pharmaceuticals, which includes a $120 million upfront payment [1] - The realization of revenue from multiple pipelines is anticipated to become a second growth curve for the company [1]

Investment Rating - The report maintains an "OUTPERFORM" rating for CSPC Pharmaceutical Group [2]. Core Views - The company's performance in 1H25 showed a revenue of CNY 13.3 billion, a year-on-year decrease of 18.5%, with a focus on licensing deals to enhance profits [14][16]. - The report anticipates that the second quarter of 2025 marked the bottom of the company's performance, with expectations for improvement in the second half of the year [4][16]. Financial Performance Summary - **1H25 Results**: Revenue was CNY 13.3 billion (-18.5% y-o-y), with finished drug revenue at CNY 10.2 billion (-24% y-o-y) and API revenue at CNY 2.1 billion (+12% y-o-y). Gross profit margin (GPM) was 65.6% (-5.9 percentage points) [14][15]. - **2Q25 Results**: Revenue reached CNY 6.3 billion (-14% y-o-y), with finished drug revenue at CNY 4.7 billion (-21% y-o-y). GPM was 64.0% (-6.7 percentage points) [15][16]. - **Net Profit**: Net profit attributable to shareholders was CNY 2.5 billion (-24% y-o-y) in 1H25 and CNY 1.1 billion (-24% y-o-y) in 2Q25 [14][15]. Business Development and Licensing Opportunities - The company is expected to secure three major out-licensing deals totaling over USD 5 billion within the year, with SYS6010 (EGFR ADC) anticipated to be a significant transaction [17][21]. - The report highlights the potential for the oral GLP-1 drug to expand into global markets, tapping into obesity, diabetes, and metabolic dysfunction-associated steatohepatitis (MASH) markets [17][21]. Clinical Development Progress - SYS6010 is progressing well in both domestic and international clinical trials, with over 1,000 patients enrolled globally [18][19]. - The management is actively pursuing multiple indications for SYS6010, including breast cancer and gastrointestinal tumors, with clinical trial plans expected to commence soon [18][19]. Valuation and Forecast Adjustments - Revenue forecasts for FY25 and FY26 have been adjusted to CNY 29.4 billion and CNY 31.2 billion, respectively, reflecting the impact of volume-based procurement and negotiations [21]. - The target price is set at HKD 13.11, based on a 2026 P/E ratio of 29.1x and an EPS forecast of HKD 0.45 [21].