"作为一家科技型药企，我们在新药研发、药品生产、市场推广等方面需要持续稳定的资金支持。自2017年成立以来，从初创期到成长期，在我们每次需要 资金周转的时候，农商银行总能及时给予我们帮助，第一时间给我们递上'接力棒'，是我们成长路上的'好伙伴''好帮手'。"山东出有限公司行政总监王群表 示。 近年来，利津农商银行聚焦战略新兴行业，不断创新金融产品，持续提高服务能力，全力构建贯穿科技型企业全生命周期的"接力式"金融产品供给体系，以 高质量的金融供给激发科技型企业新活力，助力发展新质生产力。根据支持小微企业融资协调工作机制要求，利津农商银行组织精干力量，通过"千企万户 大走访"重点对接服务全县高新技术企业、专精特新企业、科技型中小企业，为创新能力强、市场潜力大的科技型企业提供全生命周期金融服务。截至6月 末，该行共计为全县35家科创企业投放贷款近7亿元。 （通讯员 徐鹏升 庄瑞莉） 日前，国家专精特新"小巨人"企业—山东道合药业有限公司年产1400吨特色原料药项目建设投产，实现了塞来昔布、利伐沙班等原料药和医药中间体的质量 提升、降本增效和链条延伸。 在项目筹备初期，该企业因资金回笼不及时，能不能顺利申请到一笔流 ...

Group 1: Sales and Revenue Projections - The projected revenue for the new pharmaceutical raw materials market in 2024 is 180 million, with expectations for 2025 being similarly optimistic [1] - The total sales revenue for the company in 2025 is estimated to be around 850 million, with a growth rate of approximately 10% expected due to new capacity being released [3] - The revenue from old products may see a slight decline in 2025, but overall income is expected to grow in 2026 after the expansion of Celecoxib [2] Group 2: Production Capacity and Utilization - The production capacity for Celecoxib is set to increase from 170 tons to 500-600 tons by the end of this year [1] - The utilization rate for the first phase of the second plant is expected to be around 60-70% in 2025, with one workshop having completed expansion in May [2] - Two workshops in the second phase of the second plant are expected to begin trial production in the second half of this year, with full capacity release anticipated in 2026 [2] Group 3: Market and Competitive Landscape - The company faces competition from Indian firms, with varying cost advantages across different products; however, the company excels in synthesis process maturity and R&D speed [3] - The company anticipates strong sales performance for new products such as Rivaroxaban, Apixaban, and others in the future [3] Group 4: Research and Development - The company plans to maintain a high level of R&D investment, projected to be over 7% of revenue in 2025 and beyond [2] - The new R&D building is expected to be operational this year, leading to an increase in personnel and corresponding R&D expenditure [2]

Core Viewpoint - Lu Kang Pharmaceutical has received approval from the National Medical Products Administration for the market entry of Celecoxib, marking a significant milestone after substantial R&D investment [1][5]. Group 1: Product Approval and Market Potential - Celecoxib, developed by Pfizer, is the first selective COX-2 inhibitor approved globally, used for treating conditions like osteoarthritis, rheumatoid arthritis, acute pain, and ankylosing spondylitis [5]. - In 2023, sales of Celecoxib capsules in China's major markets exceeded 800 million yuan, ranking among the top 8 products in the category of oral anti-inflammatory and anti-rheumatic drugs, with a projected growth of 5.05% in the first half of 2024 [5]. - The demand for Celecoxib raw materials in China has been increasing, with usage rising from 91.62 tons in 2022 to 109.7 tons in 2023, reflecting a year-on-year growth rate of 19.7% [5]. Group 2: Competitive Landscape and Company Strategy - There are currently 53 registered raw material drug numbers for Celecoxib in China, with 38 passing the review process, indicating a competitive market [5]. - Companies like Hengrui Medicine and CSPC Pharmaceutical have already secured bids in the third batch of national centralized procurement for Celecoxib capsules [5]. - Lu Kang Pharmaceutical has invested a total of 14.899 million yuan in the R&D of Celecoxib raw materials, positioning itself for future product quality control and cost management advantages [5][7]. Group 3: Company Performance and Market Response - Lu Kang Pharmaceutical has shown steady revenue growth, with projected revenue of 6.233 billion yuan in 2024, a year-on-year increase of 1.41%, and a net profit of 408 million yuan, up 59.02% [7]. - The company's stock price has increased by 8.16% year-to-date, closing at 10.33 yuan per share on May 8, 2023, despite a slight daily decline [7].

Investment Rating - The report indicates a positive outlook for the pharmaceutical raw materials sector, highlighting a significant profit growth in Q1 and an expected improvement in industry supply and demand dynamics [3][4]. Core Insights - The pharmaceutical raw materials sector experienced a revenue of CNY 1176.77 billion in 2024, a year-on-year increase of 6.74%, with a net profit of CNY 150.46 billion, reflecting a growth of 27.89% [3][4][21]. - In Q1 2025, the sector's revenue was CNY 295.46 billion, a slight decline of 0.48% year-on-year, but net profit increased by 20.87% to CNY 45.62 billion [3][4][21]. - The report emphasizes that the rapid profit growth is attributed to several factors, including a low base in H2 2023, the end of inventory destocking by global downstream manufacturers, and improved product pricing stability [3][4][21][23]. Summary by Sections Q1 Performance - The raw materials sector's revenue was stable year-on-year, with a slight decline in Q1 2025 compared to the previous year, while profits showed significant growth [3][4][21]. - The sector's gross margin improved to 38.14% in Q1 2025, up 1.76 percentage points year-on-year, and the net margin reached 15.41%, an increase of 2.63 percentage points [4][25]. Industry Concentration - The top 10 companies in the raw materials sector contributed over 73% of total revenue in 2024, with significant contributions from companies like New and Cheng and Pro Pharmaceutical [31][33]. - In Q1 2025, the top 10 companies accounted for 73.19% of total revenue, indicating a slight decrease in concentration compared to the previous year [33][34]. Valuation and Construction Projects - The report notes that the valuation of the raw materials sector remains at historical lows, with a PE ratio of 30.26x at the end of 2024 and 33.97x at the end of Q1 2025 [5][42]. - The total construction projects in the sector decreased to CNY 163.57 billion by Q1 2025, reflecting a decline of 4.31% year-on-year, indicating a slowdown in capacity expansion [9][44]. Investment Recommendations - The report suggests focusing on companies with strong performance certainty in the formulation and CDMO sectors, such as Aorite and Pro Pharmaceutical, as well as those with significant new product contributions [10][38]. - It highlights the potential for increased demand for raw materials due to the expiration of patents for top-selling small molecule drugs in the coming years [6][42].

Core Viewpoint - The approval of Celecoxib by the National Medical Products Administration enhances the company's market competitiveness and is expected to positively impact its operating performance [1] Company Summary - The company has received the approval notice for the marketing application of Celecoxib from the National Medical Products Administration [1] - Cumulative investment in the research and development of this drug amounts to approximately RMB 14.899 million [1] - The approval of Celecoxib is seen as a significant boost for the company's market position [1]

Group 1: Company Overview and Market Position - The company is a leading player in the nitroimidazole antibiotic sector, particularly known for its metronidazole raw materials, with the longest industrial chain and the most product varieties globally [2][3] - The main products include metronidazole and its derivatives, with the largest global production capacity and market share, recognized for product quality and cost competitiveness [2][3] Group 2: Performance and Challenges - In 2024, the company faced a significant decline in performance, primarily due to the lithium hexafluorophosphate and metronidazole businesses, with a notable drop in sales prices despite increased sales volume [3][4] - The lithium battery materials sector experienced intensified competition, leading to lower sales prices for lithium hexafluorophosphate, which adversely affected profitability [3][4] - The decline in metronidazole profitability was attributed to increased competition and a decrease in product unit prices, which fell more than the reduction in unit costs [3][4] Group 3: Strategic Responses - The company has implemented a multi-faceted strategy to address current challenges, including cost optimization through production line upgrades and supply chain management [3][4] - Increased investment in research and development to accelerate product technology upgrades and new product development is a key focus [3][4] - Efforts to expand into high-margin product markets are underway to enhance overall profitability [3][4] Group 4: Financial Health and Future Outlook - The company maintains a healthy cash flow and robust financial structure, ensuring sufficient reserves for future operations and investment plans [4] - There are no current risks of delisting as per the Shenzhen Stock Exchange regulations [4] - The company has received approvals for new drug applications, including for sitagliptin phosphate and celecoxib, indicating ongoing product development [4]

以下文章来源于每日人物 ，作者每人作者 每日人物 . 轻商业，懂生活。 文 ｜ 饶桐语 宋春光 编辑 ｜ Yang 来源｜ 每日人物（ID： meirirenwu） 封面来源 ｜ Pixabay "口袋里就这么点钱， 你让我囤更多，我也没办法。" 红果果，媒体人，囤苹果手机，坐标中国 我唯一囤的东西，是一台iPhone 16。给我送货的快递员说，这几天苹果的订单涨得非常猛，就连说话间，他的手机还不断冒出新的接单提醒，一看，全 是买苹果的。 不止我，就这两天，我身边所有有换苹果手机、电脑意愿的朋友们，都连夜赶在关税落地前下单了。一个9人的好友群，加起来一共买了3台电脑，2台手 机。其中一个朋友，特意去线下买电脑，她告诉我，"跑了两家店，都断货了"，好不容易才买到。我们都开玩笑说，"这是牛马抓紧给自己配最好的鞍 鞯"。 一天一个价。 毕竟，对于一个普通的年轻人来说，最容易接触到、相对最需要的美国品牌，或许只有苹果了。着急下单，确实是因为关税的刺激。我是典型的"等等 党"。去年11月，我就已经很想换手机了，老手机用了四五年，变得很卡顿。但是我一直没买，刚开始想等等今年的新款，后来又盘算着等一个更好的价 格。社交平台 ...

证券简称： 海昇药业 证券代码： 870656 浙江海昇药业股份有限公司 1-1-0 浙江省衢州市高新技术产业园区华阳路 36 号 中国证监会和北京证券交易所对本次发行所作的任何决定或意见，均不表明其对注册申 请文件及所披露信息的真实性、准确性、完整性作出保证，也不表明其对发行人的盈利能力、 投资价值或者对投资者的收益作出实质性判断或者保证。任何与之相反的声明均属虚假不实 陈述。 浙江海昇药业股份有限公司招股说明书（申报稿） 根据《证券法》的规定，股票依法发行后，发行人经营与收益的变化，由发行人自行负 责；投资者自主判断发行人的投资价值，自主作出投资决策，自行承担股票依法发行后因发 行人经营与收益变化或者股票价格变动引致的投资风险。 本公司的发行申请尚未经中国证监会注册。本招股说明书申报稿不具有据以发行股票的法律效 力，投资者应当以正式公告的招股说明书全文作为投资决定的依据。 1-1-1 声明 发行人及全体董事、监事、高级管理人员承诺招股说明书及其他信息披露资料不存在虚 假记载、误导性陈述或者重大遗漏，并对其真实性、准确性、完整性承担相应的法律责任。 本次股票发行后拟在北京证券交易所上市，该市场具有较高的投资 ...

浙江海森药业股份有限公司 首次公开发行股票并在主板上市发行公告 保荐人（主承销商）：中信证券股份有限公司 特别提示 浙江海森药业股份有限公司（以下简称"海森药业"、"发行人"或"公司"） 根据《证券发行与承销管理办法》（证监会令【第 208 号】）（以下简称"《管 理办法》"）、《首次公开发行股票注册管理办法》（证监会令【第 205 号】） （以下简称"《注册办法》"）、《深圳证券交易所首次公开发行证券发行与承 销业务实施细则》（深证上〔2023〕100 号）（以下简称"《业务实施细则》"）、 《深圳市场首次公开发行股票网上发行实施细则》（深证上〔2018〕279 号）（以 下简称"《网上发行实施细则》"）及《深圳市场首次公开发行股票网下发行实 施细则（2023 年修订）》（深证上〔2023〕110 号）（以下简称"《网下发行实 施细则》"）、《首次公开发行证券承销业务规则》（中证协发〔2023〕18 号） （以下简称"《承销业务规则》"）、《首次公开发行证券网下投资者管理规则》 （中证协发〔2023〕19 号）（以下简称"《网下投资者管理规则》"）等有关股 票发行上市规则和最新操作指引等相关法律法规、监管规 ...

证券简称： 峆一药业 证券代码： 430478 安徽峆一药业股份有限公司 安徽省天长市杨村工业区 安徽峆一药业股份有限公司招股说明书（申报稿） 本公司的发行申请尚未经中国证监会注册。本招股说明书申报稿不具有据以发行股票的法律 效力，投资者应当以正式公告的招股说明书全文作为投资决定的依据。 本次股票发行后拟在北京证券交易所上市，该市场具有较高的投资风险。北京证券交易所主 要服务创新型中小企业，上市公司具有经营风险高、业绩不稳定、退市风险高等特点，投资者面 临较大的市场风险。投资者应充分了解北京证券交易所市场的投资风险及本公司所披露的风险因 素，审慎作出投资决定。 保荐机构（主承销商） （安徽省合肥市梅山路 18 号） 联席主承销商 （中国（四川）自由贸易试验区成都市高新区交子大道 177 号中 1-1-0 海国际中心 B 座 17 楼） 中国证监会和北京证券交易所对本次发行所作的任何决定或意见，均不表明其对注册申 请文件及所披露信息的真实性、准确性、完整性作出保证，也不表明其对发行人的盈利能力、 投资价值或者对投资者的收益作出实质性判断或者保证。任何与之相反的声明均属虚假不实 陈述。 根据《证券法》的规定，股票 ...