BeOne Medicines AG (BeOne Medicines Ltd.) (BeOne Medicines SA) 百济神州有限公司 之 组织章程细则 （根据于2025年4月28日通过的特别决议案予以采纳） Abschnitt 1 第一章 Firma, Sitz, Zweck und Dauer der 公司名称、注册地、经营宗旨和存续期限 Gesellschaft Artikel 1 第1条 Name, Sitz Unter der Firma BeOne Medicines AG 公司名称、 BeOne Medicines Ltd. (BeOne Medicines AG) (BeOne Medicines Ltd) (BeOne Medicines 注册地 (BeOne Medicines SA)（"本公司"）系一家公 SA) (die Gesellschaft) besteht eine 司，注册地为瑞士巴塞尔城市州巴塞尔。 Aktiengesellschaft mit Sitz in Basel, Kanton Basel-Stadt, Schweiz. Artikel 2 第2条 Zwe ...

每经记者｜叶峰 每经编辑｜肖芮冬 市场早盘震荡调整，创业板指领跌。盘面上热点集中在消费和医药两大方向。在ETF市场，与创新药相关的多只ETF涨幅居前。 | 代码 | 名称 | 现价 涨跌幅 17 | | --- | --- | --- | | 159570.SZ | 港股通创新药ETF | 1.297 2.61% | | 159567.SZ | 港股创新药ETF | 1.287 2.22% | | 513120.SH | 港股创新药ETF | 0.971 2.21% | | 513780.SH | 港股创新药50ETF | 1.241 1.97% | | 520700.SH > 港股创新药ETF基金 | | 1.194 - 1.88% | | 159217.SZ 港股通创新药ETF工银 | | 1.058 1.93% | | 样本代码 | 样本简称 | 所属行业 | 总市值* | | --- | --- | --- | --- | | 01801 | 信达生物 | 矢药卫生 | 885.89 | | 06160 | 百济神州 | 医药卫生 | 2034.42 | | 09926 | 康方生物 | 矢药卫生 | ...

Policy Developments - The National Medical Products Administration (NMPA) has announced the implementation of the "Quality Management Standards for Online Sales of Medical Devices," effective from October 1, 2025. Regulatory authorities are required to guide online sellers and e-commerce platforms in conducting internal training and assessments related to quality management systems, product information display, and risk monitoring [2]. Drug and Device Approvals - BeiGene announced positive results from the Phase 2 clinical trial (DeLLphi-307) of tarlatamab for treating extensive-stage small cell lung cancer (ES-SCLC) patients in China, with detailed data to be presented at an upcoming medical conference [4]. Capital Market Activities - Shanghai BoYin Biotechnology Co., Ltd. has completed a multi-million angel round financing, led by Zhangjiang Life and Health Industry Incubation Angel Fund, with funds aimed at advancing the company's product pipeline and early clinical validation of its first product [7]. Industry Developments - Yuheng Pharmaceutical has signed a co-promotion agreement with Xinghe Pharmaceutical for Pemafibrate, a novel selective PPARα modulator, which will take effect on June 1, 2025. This agreement is expected to enhance Yuheng's product pipeline and potential profit growth, although it will face competition from established products [9]. Shareholder Activities - Chengdu XianDao announced that shareholder Anji Dongfang Jiayu Enterprise Management Partnership reduced its stake by 1 million shares, decreasing its ownership from 6.2% to 5.95% [12]. - BioVeda China RMB Investment Limited plans to reduce its stake in AoJing Medical by up to 135,550 shares, having already reduced its holdings by 34,510 shares, representing 0.25% of the total shares [13].

金融界2025年5月26日消息，工银前沿医疗股票A(001717) 最新净值2.9540元，下跌1.86%。该基金近1个 月收益率4.79%，同类排名62|864；近3个月收益率9.08%，同类排名51|853；今年来收益率12.28%，同 类排名93|850。 工银前沿医疗股票A股票持仓前十占比合计59.05%，分别为：恒瑞医药（10.11%）、科伦药业 （8.01%）、药明康德（7.72%）、百济神州-U（6.85%）、信立泰（4.90%）、泽璟制药-U （4.77%）、鱼跃医疗（4.60%）、新诺威（4.36%）、华东医药（4.20%）、海思科（3.53%）。 来源：金融界 公开资料显示，工银前沿医疗股票A基金成立于2016年2月3日，截至2025年3月31日，工银前沿医疗股 票A规模90.81亿元，基金经理为赵蓓。 简历显示：赵蓓女士:硕士,曾在中再资产管理股份有限公司担任投资经理助理。2010年加入工银瑞信,现 任研究部副总监、医疗保健研究团队负责人,2014年11月18日至今,担任工银医疗保健行业股票型基金基 金经理;2015年4月28日至今,担任工银瑞信养老产业股票型基金基金经理;2016年2月 ...

Core Viewpoint - The article discusses the performance and holdings of the Industrial and Commercial Bank of China Medical Healthcare Stock Fund, highlighting its recent net value, returns, and top holdings [1]. Fund Performance - The latest net value of the ICBC Medical Healthcare Stock Fund is 2.5580 yuan, reflecting a decrease of 1.16% - The fund's return over the past month is 3.52%, ranking 172 out of 940 in its category - Over the last six months, the return is 9.79%, with a ranking of 202 out of 914 - Year-to-date, the return stands at 12.24%, ranking 98 out of 926 [1]. Fund Holdings - The top ten holdings of the ICBC Medical Healthcare Stock Fund account for a total of 39.79%, with the following key positions: - Heng Rui Medicine: 8.90% - WuXi AppTec: 5.12% - Aier Eye Hospital: 4.94% - BeiGene: 3.77% - Zai Lab: 3.52% - New Horizon Health: 3.27% - Mindray Medical: 2.80% - Yuwell Medical: 2.76% - United Imaging Healthcare: 2.47% - Innovent Biologics: 2.24% [1]. Fund Management - The ICBC Medical Healthcare Stock Fund was established on November 18, 2014, and as of March 31, 2025, it has a total scale of 2.724 billion yuan - The fund is managed by Zhao Bei and Ding Yang, both of whom have extensive experience in the healthcare sector [1][2].

Core Viewpoint - The recent developments in the innovative drug sector, particularly the record-breaking licensing deal and the upcoming ASCO conference, highlight the growing competitiveness and potential of Chinese pharmaceutical companies in the global market [4][5]. Group 1: Market Performance - The Hong Kong Innovative Drug ETF (159570) opened high but closed lower, experiencing a 1% pullback after four days of gains last week, with trading volume reaching 300 million, indicating strong liquidity [1]. - Major component stocks of the ETF mostly declined, with notable drops including a more than 4% decrease for 3SBio and over 3% for both WuXi AppTec and Rongchang Biopharmaceutical [2]. Group 2: Licensing Deal - A historic licensing agreement was reached where Pfizer will pay a $1.25 billion upfront fee to Chinese companies for the PD-1/VEGF dual antibody SSGJ-707, with potential total payments reaching $4.8 billion [4]. - This deal sets a new record for Chinese innovative drugs entering the international market and is expected to enhance market valuation expectations for the innovative drug sector [4]. Group 3: ASCO Conference Insights - The upcoming ASCO conference is anticipated to showcase the global competitiveness of Chinese pharmaceutical companies, with numerous clinical studies being presented [5]. - Key highlights include the performance of domestic drugs that have shown potential to outperform established treatments, such as the combination of Bemarituzumab and Anlotinib against Keytruda in NSCLC [5]. - CAR-T therapies are also making significant strides, with Kintor Pharmaceuticals presenting promising data for their CLDN18.2 CAR-T therapy [5]. Group 4: Innovative Drug ETF Characteristics - The Hong Kong Innovative Drug ETF (159570) has a high concentration in innovative drugs, with over 85% of its weight in this category, making it the highest among all pharmaceutical indices [6]. - The ETF features a low valuation, with a five-year price-to-sales ratio at the 48.5th percentile, indicating potential undervaluation in the innovative drug sector [6].

公开资料显示，工银前沿医疗股票C基金成立于2020年11月23日，截至2025年3月31日，工银前沿医疗 股票C规模13.80亿元，基金经理为赵蓓。 金融界2025年5月21日消息，工银前沿医疗股票C(010685) 最新净值2.9140元，增长1.53%。该基金近1个 月收益率4.11%，同类排名420|1001；近3个月收益率9.30%，同类排名81|988；今年来收益率13.47%， 同类排名116|978。 工银前沿医疗股票C股票持仓前十占比合计59.05%，分别为：恒瑞医药（10.11%）、科伦药业 （8.01%）、XD药明康（7.72%）、百济神州-U（6.85%）、信立泰（4.90%）、泽璟制药-U （4.77%）、鱼跃医疗（4.60%）、新诺威（4.36%）、华东医药（4.20%）、海思科（3.53%）。 来源：金融界 简历显示：赵蓓女士:硕士,曾在中再资产管理股份有限公司担任投资经理助理。2010年加入工银瑞信,现 任研究部副总监、医疗保健研究团队负责人,2014年11月18日至今,担任工银医疗保健行业股票型基金基 金经理;2015年4月28日至今,担任工银瑞信养老产业股票型基金基金经理;2 ...

风险提示：本文所提到的观点仅代表个人的意见，所涉及标的不作推荐，据此买卖，风险自负。 作者： 纸上谈钱 来源：雪球 01 救命大药 ： 中国创新药公司正不可阻挡的崛起 作为医药企业 ， 能够提供改善患者疾病的产品 ， 是永远的主题 。 我知道迄今为止 ， 仍有太多的人怀疑 中国的创新药公司产品力不够 ， 知识储备不够 ， 技术不够 ， 人才不够等等等等 。 但是 ， 我仅仅提供 以下几个例子 ： 百济神州为什么营业额从2022年95亿 ， 2023年174亿 ， 2024年272亿 ， 到2025年的指引380亿 ， 以 每年百亿级别的跨度在前进 。 如果你真的体会了泽布替尼对患者的帮助 ， 你就明白了 ， 简单说 ， 服用 泽布替尼的患者 ， 普遍生存周期超过了5年 ， 部分患者甚至痊愈了 。 这是多么令人欢欣鼓舞的消息啊 。 不仅仅百济神州 ， 请继续看以下几个例子 ： 这是远大医药 。 这是荣昌生物 这是科济药业 ， 丝毫不吹牛的说 ， 本人两年前就已经明白了科济产品的恐怖 ， 但是我总是担心中国的支 付能力 ， 因此今年错过了10倍的大牛股 ， 为此 ， 我每天都在打自己几个耳光 ， 我他妈得是有多蠢 ...

Group 1 - The core viewpoint of the news highlights the strong performance of the Hong Kong technology sector, with the CSI Hong Kong Stock Connect Technology Index rising by 1.68% as of May 20, 2025, and notable increases in individual stocks such as 33.24% for 3SBio and 5.31% for Li Auto [1] - The Hong Kong Technology ETF has shown a weekly increase of 0.30% and ranks in the top 1/5 among comparable funds, indicating a positive trend in the technology sector [1] - The trading volume of the Hong Kong Technology ETF reached 48.54 million yuan, with a turnover rate of 8.09%, reflecting strong liquidity in the market [1] Group 2 - 3SBio has entered into an exclusive licensing agreement with Pfizer for the PD-1/VEGF bispecific antibody, which is expected to enhance its market position and revenue potential [2] - The pharmaceutical industry is anticipated to experience valuation recovery in 2025, driven by factors such as innovative drug exports, optimization of domestic procurement policies, and the implementation of new medical insurance directories [2] - The CSI Hong Kong Stock Connect Technology Index comprises 50 large-cap technology companies with high R&D investment and revenue growth, indicating a focus on leading firms in the sector [2][3] Group 3 - As of April 30, 2025, the top ten weighted stocks in the CSI Hong Kong Stock Connect Technology Index account for 71.55% of the index, with major players including Xiaomi, Alibaba, and Tencent [3]

Group 1 - The Hong Kong pharmaceutical stocks are experiencing a strong performance, with notable gains in several companies [1] - Yiming Anke-B (01541.HK) has increased by 8.38%, while Cornerstone Pharmaceuticals-B (02616.HK) has risen by 7.82% [1] - Other companies such as Baijie Shenzhou (06160.HK), Jakes-B (01167.HK), and Ying'en Biotechnology-B (09606.HK) have also shown positive movements, with increases of 3.25%, 2.80%, and 2.68% respectively [1]